Clinical trials: Congestive Heart Failure Acute
Chronic or Acute Advanced Heart Failure
South Of France Cardiac Assist Registry
Chronic heart failure is a common disease. It is also a serious disease with a mortality of 50% at 5 years, representing a significant cost in terms of public health expenditure.
- Trial name
- SOFCAR (NCT02877446)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Heart Failure
Carbohydrate Antigen 125-guided Therapy in Heart Failure
Preliminary data suggest a potential role for monitoring and up-titrate pharmacological therapy of plasma levels of antigen carbohydrate 125 (CA125) following and admission for acute heart failure (AHF).
- Trial name
- CHANCE-HF (NCT02008110)
- Testing
- CA125 guided strategy, Standard treatment strategy
- Where
- Spain
- Volunteers
- 360 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Heart Failure, Acute Heart Failure
Early or Non-revoked in Hospital-day in Patients With Acute Heart Failure
Heart failure is one of the major causes of hospitalization in Brazil and worldwide. Recent studies attempt to identify readmission and prognostic markers at the time of discharge from these patients.
- Trial name
- HospDia (NCT03717636)
- Testing
- medical evaluation
- Where
- Brazil
- Volunteers
- 720 people
- Sponsor
- University of Sao Paulo General Hospital
Congestive Heart Failure
Effects of Acute L-NMMA Treatment on Renal Hemodynamics and Vasoactive Hormones in Patients With Congestive Heart Failure
The study tests the hypothesis that nitric oxide availability is changed in congestive heart failure with regard to the regulation of renal hemodynamics, renal sodium excretion and release of vasoactive hormones.
- Trial name
- NCT00344734
- Testing
- Ng-monomethyl-L-arginine (drug)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Heart Failure
Low Level Laser Therapy in Heart Failure Patients.
Heart failure (HF) is an important public health problem being considered an emerging epidemic, therefore, strategies are essential to improve symptoms and to decrease the money expenditure on healthcare.
- Trial name
- NCT02508792
- Testing
- LASER
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Congestive Heart Failure
Hemodynamic Assessment in Acute Decompensated Heart Failure
This study will assess the ability of a novel optical measurement system to determine changes in the hemodynamic status of heart failure patients admitted to the hospital with a primary diagnosis of acute decompensated heart…
- Trial name
- NCT03535909
- Testing
- Noninvasive Hemodynamic Measurement System
- Where
- 2 sites in United States, Croatia
- Volunteers
- 5 people
- Sponsor
- Rodin Scientific LLC
Cardiogenic Shock, Ventricular Arrythmia
Innovative Technologies for the Treatment of Pulmonary and Heart Failure
The purpose of the program. Formulation of new treatments for heart and pulmonary failure through using organ-replacing technologies.
- Conditions
- Cardiogenic Shock, Ventricular Arrythmia, Cardiac Arrest With Successful Resuscitation, Sepsis
- Trial name
- NCT05090930
- Testing
- HA330 - Jafron Biomedical Co., Ltd., China - extracorporeal hemocorrection, CytoSorb (CytoSorbents Corp., USA) - an extracorporeal cytokine adsorber
- Where
- Kazakhstan
- Volunteers
- 100 people
- Sponsor
- National Research Center for Cardiac Surgery, Kazakhstan
Heart Failure, Systolic Heart Failure
Heart Failure (HF) Outpatient Monitoring Evaluation (HOME) Study
The purpose of this study is to determine if heart failure subjects whose treatment is assisted by home BNP measurements integrated into a home health management system will have better clinical outcomes than subjects whose…
- Conditions
- Heart Failure, Systolic Heart Failure, Acute Decompensated Heart Failure
- Trial name
- HOME (NCT01347567)
- Testing
- Interventions with heart failure medications
- Where
- 7 sites in Australia, Ireland and 4 more
- Volunteers
- 145 people
- Sponsor
- Alere San Diego
Heart Failure
A Multifaceted Nurse-based Strategy Reduces HEart FaiLure Morbidity in PatiENts Admitted for Acute Decompensated Heart Failure in Brazil
The home based intervention is a multidisciplinary approach that has shown benefit in the follow-up of patients with Heart Failure (HF).
- Trial name
- HELEN II (NCT01213875)
- Testing
- Home based education
- Where
- Brazil
- Volunteers
- 252 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Heart Disease, Heart Failure With Preserved Ejection Fraction
Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction
Heart failure with preserved ejection fraction (HFpEF) is a major public health problem that has no proven effective treatment. This study assessed the effects of acute nitrite administration on resting and exercise hemodynamics…
- Conditions
- Heart Disease, Heart Failure With Preserved Ejection Fraction, Exercise Intolerance, Pulmonary Hypertension
- Trial name
- NCT01932606
- Testing
- Nitrite
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Barry Borlaug
Heart Failure, Acute Coronary Syndrome
Platform Therapeutic Education in Heart Failure and Coronary Disease
A first therapeutic education is given before patient's discharge at the hospital, then a dedicated nurse follows patients through the phone,regularly according to patients' needs, continues to give advise on risk factors…
- Conditions
- Heart Failure, Acute Coronary Syndrome, Coronary Bypass Graft Stenosis of Native Artery Graft
- Trial name
- METISCARDIO (NCT01869452)
- Testing
- therapeutic education
- Where
- 4 sites in France
- Volunteers
- 555 people
- Sponsor
- Resicard
Acute Heart Failure, Acute Decompensation of Chronic Heart Failure
Tezosentan in Acute Heart Failure
The randomized patients with acute heart failure will be stratified based on the presence or absence of a Swan-Ganz catheter and assigned to receive either tezosentan 5 mg/h for the first 30 minutes and 1 mg/h thereafter or…
- Conditions
- Acute Heart Failure, Acute Decompensation of Chronic Heart Failure, New Onset of Heart Failure
- Trial name
- VERITAS 1 (NCT00525707)
- Testing
- tezosentan
- Where
- 35 sites in United States, Austria and 8 more
- Volunteers
- 735 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
ST Segment Elevation Myocardial Infarction, Heart Failure
Doxycycline to Protect Heart Muscle After Heart Attacks
Current medical treatment allows more people to survive heart attacks than in the past. However, some of the survivors suffer heart disease and require hospitalization later on.
- Trial name
- NCT03508232
- Testing
- Doxycycline Hyclate
- Where
- Canada
- Volunteers
- 174 people
- Sponsor
- University of Alberta
Acute Heart Failure
Investigating aCute heArt failuRe Decongestion Guided by Lung UltraSonography
The goal of this clinical trial is to investigate whether a lung ultrasonography (LUS)-guided decongestion strategy in adults hospitalized for acute heart failure (AHF) can improve patient-centered outcomes.
- Trial name
- IcarUS (NCT06465498)
- Testing
- LUS decongestive strategy, PE decongestive strategy
- Where
- 5 sites in Switzerland
- Volunteers
- 222 people
- Sponsor
- Antonio Leidi
Cardiovascular Diseases, Coronary Artery Disease
Optimising Secondary Prevention and Quality of Life in Early Cardiac Rehabilitation
The primary aim of this research is to explore the adherence and drop-out from early cardiac rehabilitation (CR), to inform interventions to support patient's adherence to CR and facilitate maintenance.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Myocardial Infarction, Acute Coronary Syndrome
- Trial name
- OSPREY-CR (NCT04781699)
- Where
- 6 sites in United Kingdom
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Acute Lung Injury, Pneumonia
Gases Humidification During Noninvasive Ventilation : Heat and Moisture Exchanger or Heated Humidifier ?
To humidify gases during non invasive ventilation, both to heated humidifier (HH) and heat and moisture exchanger (HME) are routinely used.
- Conditions
- Acute Lung Injury, Pneumonia, Chronic Obstructive Pulmonary Disease, Acute Heart Failure
- Trial name
- NCT00221819
- Testing
- heated humidifier (device), Heat and moisture exchanger (device)
- Where
- France
- Sponsor
- University Hospital, Bordeaux
Acute Decompensated Heart Failure
Readily Available Urinary Sodium Analysis in Patients With Acute Decompensated Heart Failure
The goal of this clinical trial is to compare physician-guided (SOC) versus nurse-led natriuresis-guided diuretic therapy in patients with acute decompensated heart failure (ADHF).
- Trial name
- EASY-HF (NCT06278792)
- Testing
- Diuretic protocol, Standard of Care
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Ziekenhuis Oost-Limburg
Heart Failure, Congestive, Heart Decompensation
Longitudinal Registry for Advanced Heart Failure Patients
The purpose of this study is to gather information to better understand the characteristics, medical management techniques and outcomes of patients with chronic severe Heart Failure (HF).
- Trial name
- NCT00364416
- Testing
- Any treatment used to treat CHF
- Volunteers
- 1,466 people
- Sponsor
- Scios, Inc.
Heart Failure
SAFEty and Efficacy of HOME-based Hospitalization Versus Inpatient Care for Patients With Acute Heart Failure in Chronic Heart Failure.
Evaluation of the efficacy, safety and and cost of home care versus conventional hospitalization care at 3-months in patients with worsening chronic heart failure.
- Trial name
- SAFE-HOME (NCT03156686)
- Testing
- HOME-based hospitalization
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- French Cardiology Society
Acute Heart Failure
Invasive Coronary Angiography Early in Ischemic Heart Failure
To compare the outcomes of patients with acute heart failure who undergo early coronary angiography vs. usual care
- Trial name
- ICE-HF (NCT04245605)
- Testing
- Coronary angiography
- Where
- Canada
- Volunteers
- 2,994 people
- Sponsor
- Institute for Clinical Evaluative Sciences