Clinical trials: Congestive Heart Failure Acute
Heart Failure, Acute Myocardial Infarction
Carvedilol Vascular Efficacy Trial
Beta-blockers should be administered to all patients with heart failure stages II to IV NYHA. It should also be administered to patients with stage I after myocardial infarction.
- Trial name
- CARVEDIA (NCT01484327)
- Testing
- Carvedilol
- Where
- Greece
- Volunteers
- 415 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Acute Myocardial Infarction
Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI
The purpose of this study is to evaluate the efficacy and safety of LCZ696 titrated to a target dose of 200 mg twice daily, compared to ramipril titrated to a target dose of 5 mg twice daily.
- Trial name
- PARADISE-MI (NCT02924727)
- Testing
- LCZ696 (sacubitril/valsartan), Ramipril, Valsartan
- Where
- 486 sites in United States, Argentina and 39 more
- Volunteers
- 5,669 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure, Renal Insufficiency
Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure
The purpose of this study is to evaluate the effect of levosimendan infusion, in addition to standard therapy,on renal function in patients with Acute Heart Failure,compared with standard therapy alone.
- Trial name
- NCT00527059
- Testing
- Levosimendan in addition to standard therapy, spironolactone, beta-blockers,ecc
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- University of Roma La Sapienza
Heart Failure, Acupuncture
The Effect and Safety of Low-level Laser Therapy in Acute Decompensated Heart Failure Patients.
The advantages of laser acupuncture are a non-invasive, painless, low risk of infection and high safety. Laser acupuncture as a treatment tool has the following advantages1.Painless, 2.
- Trial name
- NCT04383080
- Testing
- Acupuncture, Low-level laser therapy
- Where
- Taiwan
- Volunteers
- 17 people
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Pneumonia, Heart Failure
Hospitalization at Home: The Acute Care Home Hospital Program for Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Pneumonia, Heart Failure, Cellulitis, Urinary Tract Infections
- Trial name
- NCT02864420
- Testing
- Home hospitalization, Inpatient Hospitalization
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Brigham and Women's Hospital
Acute Heart Failure
Preemptive Lung Impedance-guided Therapy of Evolving Acute Heart Failure in Acute Myocardial Infarction Patients
It is well known that 20-25% of patients hospitalized for acute myocardial infarction will develop acute heart failure during their hospitalization.
- Trial name
- NCT01264159
- Testing
- Lung impedence-guided therapy, Usual treatment of patients with developing acute heart failure
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Hillel Yaffe Medical Center
Blood Pressure, Depression
Essential Hypotension and Allostasis Registry
The essential arterial hypotension and allostasis registry is a prospective, observational research that has the purpose of demonstrating that essential blood pressure (BP) disorders and the associated comorbidities are a result…
- Conditions
- Blood Pressure, Depression, Panic Attack, Fibromyalgia
- Trial name
- ESSENTIAL (NCT02018497)
- Where
- Colombia
- Volunteers
- 5,000 people
- Sponsor
- CES University
Acute Respiratory Failure, Heart Failure
Tracheostomy in ICU With a Double Lumen Endotracheal Tube
Percutaneous tracheostomy in Intensive care unit (ICU) is performed with the use of flexible fiberoptic bronchoscope inside the conventional single lumen endotracheal tube owned by the patients.
- Conditions
- Acute Respiratory Failure, Heart Failure, Neurological Disease
- Trial name
- NCT01691222
- Testing
- Double lumen endotracheal tube tracheostomy
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- University of Genova
Acute Heart Failure (AHF)
Heart Risk 6 Scale in Emergency Department Acute Heart Failure Patients
Detect the predictive value of the HEARTRISK6 Scale in Predicting Short-Term Serious Outcomes in emergency department acute heart failure patients in Egyptian population
- Trial name
- NCT06664073
- Volunteers
- 125 people
- Sponsor
- Assiut University
Heart Failure
Effectiveness of Ultrafiltration in Treating People With Acute Decompensated Heart Failure and Cardiorenal Syndrome (The CARRESS Study)
Heart failure is a serious condition in which the heart's ability to pump blood through the body is impaired, often making a person feel weak or fatigued.
- Trial name
- CARRESS (NCT00608491)
- Testing
- Stepped pharmacologic care, Ultrafiltration
- Where
- 9 sites in United States, Canada
- Volunteers
- 188 people
- Sponsor
- Duke University
Heart Failure Acute, Renal Dysfunction
Contrast-Induced Acute Kidney Injury Prevention in Acute Heart Failure
The K-PROSE study is a randomized clinical investigation evaluating strategies to prevent contrast-induced acute kidney injury (CI-AKI) in patients hospitalized with acute heart failure and moderate renal dysfunction (eGFR 30-75…
- Trial name
- K-PROSE (NCT07550790)
- Testing
- Furosemide, 0.9 % Normal Saline
- Where
- South Korea
- Volunteers
- 190 people
- Sponsor
- Jin Joo Park
Pulmonary Embolism With Acute Cor Pulmonale, Pulmonary Embolism
Standard-dose Apixaban AFtEr Very Low-dose ThromboLYSis for Acute Intermediate-high Risk Acute Pulmonary Embolism
The purpose of this study is to examine the degree to which pulmonary embolism (clot) can be dissolved when treated with a very low dose of a systemic thrombolytic drug (clot buster) along with standard anticoagulant therapy as…
- Conditions
- Pulmonary Embolism With Acute Cor Pulmonale, Pulmonary Embolism, Pulmonary Embolism With Pulmonary Infarction, Pulmonary Embolism Subacute Massive
- Trial name
- SAFE-LYSE (NCT03988842)
- Testing
- Alteplase, Unfractionated heparin, Apixaban
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Victor Tapson, MD
Advanced Heart Failure, Heart Transplantation
Non-invasive Evaluation of Heart Transplant Rejection- Pilot Study
The purpose of this research study is to apply new non-invasive, no-risk techniques to a cardiac transplant population for assessment of their reliability in detecting heart transplant rejection.
- Trial name
- NCT00572286
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Acute Right Heart Failure, Pulmonary Hypertension
Assessment of Peripheral Veins Doppler Ultrasound for Diagnosis of Acute Right Heart Failure in Suspicion or Follow-up of Pulmonary Hypertension
Occurrence of acute right heart failure (ARHF) remains common during pulmonary hypertension (PH). Right atrial pressure (RAP) invasive measurement is the gold standard to diagnose ARHF in order to improve diuretic treatment…
- Conditions
- Acute Right Heart Failure, Pulmonary Hypertension, Peripheral Veins Doppler Ultrasound
- Trial name
- CODOVEIN (NCT04792879)
- Testing
- Peripheral veins Doppler ultrasound
- Where
- France
- Volunteers
- 103 people
- Sponsor
- Poitiers University Hospital
Heart Failure
Strain Echo in Acute Heart Failure
The purpose of this project is to evaluate the utility of left ventricular strain as part of the assessment of patients in the emergency department with acute heart failure (HF).
- Trial name
- Strain Echo (NCT02371642)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Wayne State University
Acute Heart Failure
Rivaroxaban Once Daily Versus Dose-adjusted Vitamin K Antagonist on the Biomarkers in Acute Decompensated Heart Failure and Atrial Fibrillation (ROAD HF-AF)
Vitamin K antagonists (VKAs) are used to reduce the risk of stroke (cerebral vascular dysfunction) in AF patients. However, VKAs interact with drugs/food and the drug level is influenced by worsening of renal function, liver…
- Trial name
- NCT03490994
- Testing
- Rivaroxaban, Warfarin + LMWH
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Yonsei University
Heart Failure
Cardiac Rhythm Monitoring After Acute Decompensation for Heart Failure
The CARRYING ON for heart failure (HF) study is a national, prospective, post market interventional, multi-center, open-label, pilot trial.The purpose of the study is to assess a short term and a long term period, incidence of…
- Trial name
- CARRYINGON (NCT01216670)
- Testing
- remote patient's management
- Where
- 4 sites in Italy
- Volunteers
- 18 people
- Sponsor
- Medtronic Italia
Heart Failure
Patient Journey in Hospital With Heart Failure in Turkish Population
The purpose of this study is to compose a national database of the etiologies, clinical and demographic characteristics, using diagnostic tests, precipitating and risk factors, management of from intensive care unit or coronary…
- Trial name
- JournayHF-TR (NCT02487056)
- Testing
- Demographic and clinical characteristics, clinical history, symptoms and signs, initial emergency department evaluation, and subsequent inpatient management of HF patients
- Where
- Turkey (Türkiye)
- Volunteers
- 1,622 people
- Sponsor
- Ege University
Myocardial Infarction, Acute, Heart Failure, Left Sided
Study to Assess Efficacy and Safety of CDR132L in Patients With Reduced Left Ventricular Ejection Fraction After Myocardial Infarction
This is a Phase 2, multicenter, randomized, parallel, 3-arm, placebo-controlled study to assess efficacy and safety of CDR132L in patients with reduced Left Ventricular Ejection Fraction (LVEF) (≤ 45%) after myocardial infarction…
- Trial name
- HF-REVERT (NCT05350969)
- Testing
- CDR132L
- Where
- 49 sites in Czechia, Germany and 6 more
- Volunteers
- 294 people
- Sponsor
- Cardior Pharmaceuticals GmbH
Acute Decompensated Heart Failure (ADHF)
ExCR's Effects and Safety in Vulnerable ADHF Patients
Exercise-based cardiac rehabilitation has become a key component of the comprehensive care system for patients with stable heart failure (HF).
- Trial name
- NCT06795737
- Testing
- Exercise rehabilitation, Conventional rehabilitation
- Where
- China
- Volunteers
- 88 people
- Sponsor
- YE Jing