Clinical trials: Congestive Heart Failure Chronic
Chronic Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF)
Precision Subtyping and Prognostic Study of Heart Failure Based on Multi-Omics Integration and Clinical Indicators: A Prospective Single-Center Cohort Study
This is a prospective single-center cohort study conducted at The First Affiliated Hospital of Xinjiang Medical University, aiming to enroll 400 patients with chronic heart failure (including HFrEF, HFmrEF, HFpEF) and 200 healthy…
- Conditions
- Chronic Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
- Trial name
- HF-MultiOmics (NCT07355088)
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Xinjiang Medical University
Heart Failure
Safety Study of the Ventricular Partitioning Device (VPD) Implant System in Heart Failure Patients
The CardioKinetix Ventricular Partitioning Device (VPD) is intended to isolate the malfunctioning portion of the left ventricle in patients with symptoms of heart failure due to ischemic heart disease.
- Trial name
- PARACHUTE (NCT00573560)
- Testing
- VPD Implant System
- Where
- 7 sites in United States, Serbia
- Volunteers
- 20 people
- Sponsor
- CardioKinetix, Inc
Cachexia, Chronic Obstructive Pulmonary Disease
Safety, Tolerance and Efficacy of an Oral Nutritional Supplement in Chronic Heart Failure and Chronic Obstructive Pulmonary Disease Patients
To test the compliance, tolerance, safety and to get preliminary insights into the efficacy of a new oral nutritional supplement (containing n-3 fatty acids, amino acids and antioxidants) designed to prevent or delay cachexia and…
- Conditions
- Cachexia, Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
- Trial name
- NCT00852020
- Testing
- oral nutrition supplement, food for special medical purposes
- Where
- 4 sites in Germany, Poland
- Volunteers
- 60 people
- Sponsor
- Fresenius Kabi
Systolic Heart Failure, Iron Deficiency
Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality
The purpose of this study is to determine whether intravenous iron supplementation using ferric carboxymaltosis (FCM) extends the time-to-first-event of heart failure hospitalisations and cardiovascular (CV) death and reduces…
- Trial name
- FAIR-HF2 (NCT03036462)
- Testing
- Iron, Saline
- Where
- 51 sites in Germany, Hungary and 5 more
- Volunteers
- 1,105 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Heart Failure
V-LAP™ Left Atrium Monitoring systEm for Patients With Chronic sysTOlic & Diastolic Congestive heaRt Failure
The purpose of the trial is to evaluate the safety, usability and performance of the V-LAP™ System in adult subjects with New York Heart Association (NYHA) Class III Heart Failure.
- Trial name
- VECTOR-HF (NCT03775161)
- Testing
- V-LAP™ System
- Where
- 2 sites in Germany, Italy
- Volunteers
- 45 people
- Sponsor
- Vectorious Medical Technologies Ltd.
Ischemia, Cardiac Insufficiency
Detection and Treatment of Somatic Disease in Patients With Severe Mental Disease
In Denmark, around 2 % of the population live with severe mental disease. People with severe mental disease live 15-20 years less than the general population.
- Conditions
- Ischemia, Cardiac Insufficiency, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- NCT03428308
- Testing
- Screening, Treatment
- Volunteers
- 90 people
- Sponsor
- Intersectoral Research Unit for Health Services
Chronic Heart Failure, Fear of Movement (Fear of Physical Activity)
Fear of Activity in Situations (FActS) - Study 2016
The aim of the study is to evaluate the psychometric properties of the newly developed Fear of Activity in Situations - Heart Failure (FActS-HF 15) scale.
- Trial name
- NCT02898246
- Where
- 6 sites in Germany
- Volunteers
- 187 people
- Sponsor
- University of Trier
Chronic Heart Failure, Sleep Apnea
The Effect of Adaptive Servo Ventilation and Oxygen Therapy in Central Sleep Apnea Patients
The aim of this study is to compare the effects of Adaptive Servo Ventilation (Bipap® auto SV Advanced) and oxygen therapy in chronic heart failure patients complicated with central sleep apnea.
- Trial name
- NCT01187823
- Testing
- Adaptive servo ventilation, Nocturnal oxygen
- Where
- Japan
- Volunteers
- 43 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Heart Failure
Cohort Study of Chronic Heart Failure
The goal of this observational study is to learn about the influencing factors of chronic heart failure prognosis in heart failure patients.
- Trial name
- CHF (NCT05960890)
- Testing
- Remote monitoring assisted by community physicians
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Jiangsu Taizhou People's Hospital
Heart Failure, Kidney Failure
New Biomarkers in Heart- and Renal Failure
In this study, prognostically relevant biomarkers for cardiovascular / renal insufficiencies will be clinically evaluated, to improve the course of assessment of such disease and to gain new insights into the typical course of…
- Trial name
- IM19 Register (NCT02830464)
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- RWTH Aachen University
Chronic Systolic Heart Failure
Renal Artery Denervation in Chronic Heart Failure Study
The REACH study, is a prospective, double-blinded, randomised, controlled study of the safety and effectiveness of renal denervation in subjects with chronic systolic heart failure.
- Trial name
- REACH (NCT01639378)
- Testing
- Renal Denervation
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- Imperial College London
Cardiomyopathy, Coronary Artery Disease
Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly
The overall aim of this trial is to study the safety and efficacy of ICD implantation as a primary prevention strategy of sudden cardiac death in patients 70 years and older.
- Conditions
- Cardiomyopathy, Coronary Artery Disease, Congestive Heart Failure, Myocardial Infarction
- Trial name
- I-70 (NCT02121158)
- Testing
- Implantable Cardioverter Defibrillator, Optimal Medical Therapy
- Where
- 5 sites in United States
- Volunteers
- 167 people
- Sponsor
- VA Office of Research and Development
Chronic Heart Failure (CHF)
Assessment of the Impact of Clinical Decision Support Systems Included in Electronic Health Records
A non--interventional study to assess the impact of clinical decision support systems included in electronic health records on compliance with guidelines, including routing of patients with CHF, follow-up care, prescription and…
- Trial name
- NCT06248658
- Where
- Russia
- Volunteers
- 66,166 people
- Sponsor
- National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Congenital Complete Atrioventricular Heart Block, High Grade Atrioventricular Block
Effects of Chronic Right Ventricular Pacing in Children With Advanced Atrioventricular Block
Recent studies have shown that chronic stimulation of the right ventricle can cause deleterious effects to cardiac function and synchronicity.
- Conditions
- Congenital Complete Atrioventricular Heart Block, High Grade Atrioventricular Block, Postoperative Complete Heart Block
- Trial name
- NCT01477658
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- University of Sao Paulo
Heart Failure, Cheyne Stokes Respiration
Chronic Heart Failure - Cheyne Stokes Respiration - CS2 (3C-study)
An investigation where patients with chronic heart failure and cheyne stokes respiration, treated with adapitve servo ventilator, will improve their cardiac function and quality of life.
- Trial name
- 3C (NCT00563693)
- Testing
- ASV, without Autoset CS2
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- University of Oslo
Decompensated Chronic Heart Failure, Heart Failure NYHA Class III
Epidemiology and Prognostic of the Acute Heart Failure
EPICAL 2 (Epidemiology and prognostic of the Acute Heart Failure) is an epidemiological, observational, prospective and multicenter study.
- Conditions
- Decompensated Chronic Heart Failure, Heart Failure NYHA Class III, Acute Pulmonary Edema, Cardiogenic Shock
- Trial name
- EPICAL2 (NCT02880358)
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- Central Hospital, Nancy, France
Pulmonary Disease, Chronic Obstructive, Heart Failure
Improving Medication Adherence Through a Transitional Care Pharmacy Practice Model
The purpose of this pilot study is to determine if medication adherence is improved by a transitional care pharmacy practice model designed to integrate hospital and community pharmacists in the care and education of patients…
- Trial name
- NCT02047448
- Testing
- Pharmacist Counseling
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Wilkes University
Ischemic Heart Disease, Heart Failure
Trial of an Internet-based Platform for Managing Chronic Diseases at a Distance
In 2005, more then one-third of Canadians were burdened with one or more chronic diseases. Patients with one chronic disease often have, or are at risk for, another chronic disease.
- Conditions
- Ischemic Heart Disease, Heart Failure, Chronic Kidney Disease, Diabetes
- Trial name
- iCDM (NCT01342263)
- Testing
- iCDM
- Where
- Canada
- Volunteers
- 234 people
- Sponsor
- Simon Fraser University
Lower Extremity Edema, Lower Extremity Edema Chronic
Pedal Pump Clinical Trial on Edema V2
Previous research on the osteopathic manual technique entitled "Pedal Pump" has shown health benefits, specifically increasing lymphatic flow, decreasing lower extremity edema, and decreasing serum lactic acid after maximal…
- Conditions
- Lower Extremity Edema, Lower Extremity Edema Chronic, CHF - Congestive Heart Failure, CHF Exacerbation
- Trial name
- NCT07809516
- Testing
- Pedal Pump
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hillcrest
Diabetes Mellitus, Chronic Heart Failure
Randomized Controlled Trial of Home Telemonitoring for Elderly People
The DREAMING clinical trial is part of the DREAMING project, which has the objective to demonstrate that the DREAMING platform consisting of integrated health monitoring, alarm handling and videoconferencing services produces…
- Conditions
- Diabetes Mellitus, Chronic Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- Dreaming (NCT00893685)
- Testing
- Wireless monitors for disease specific clinical parameters.
- Where
- 6 sites in Denmark, Estonia and 4 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Health Information Management, Belgium