Clinical trials: Congestive Heart Failure Treated
Heart Failure, Acute Kidney Injury
Treatment According to Venous Excess Ultrasound Score in Patients With Heart Failure
Heart failure is a syndrome that progresses with symptoms and signs caused by cardiac dysfunction and results in a shortened life expectancy (1).
- Trial name
- NCT06341816
- Testing
- VEXUS score, NGAL
- Volunteers
- 100 people
- Sponsor
- Inonu University
Heart Failure, Prefrail Elderly
High-technology TeleRehabilitation for the Treatment of the FRAgile Patient
The aim of this randomized controlled clinical trial is to evaluate the efficacy of an 8-week sensorimotor and cognitive telerehabilitation program in frail and pre-frail older adults with stable chronic heart failure.
- Conditions
- Heart Failure, Prefrail Elderly, Frail Elderly Syndrome
- Trial name
- TeleRiab4Fra (NCT07561021)
- Testing
- Telerehabilitation, Caregiver-Supervised Home Exercise Program
- Volunteers
- 70 people
- Sponsor
- University of Salerno
Acute Heart Failure, Acute Decompensation of Chronic Heart Failure
Tezosentan in the Treatment of Acute Heart Failure
The randomized patients with acute heart failure will be stratified based on the presence or absence of a Swan-Ganz catheter and assigned to receive either tezosentan 5 mg/h for the first 30 minutes and 1 mg/h thereafter or…
- Conditions
- Acute Heart Failure, Acute Decompensation of Chronic Heart Failure, New Onset of Heart Failure
- Trial name
- VERITAS 2 (NCT00524433)
- Testing
- tezosentan
- Where
- 42 sites in United States, Australia and 6 more
- Volunteers
- 713 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Heart Failure With Reduced Ejection Fraction
EHR Nudges to Improve Quality of Care in HF
The purpose of this pilot feasibility study is to test a pharmacist-facing clinical decision support tool designed to increase adherence to guideline-directed medical therapy and evaluate the tool using the Reach, Effectiveness…
- Trial name
- NCT06103565
- Testing
- Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Northwestern University
Heart Failure With Preserved Ejection Fraction, Hypertension
BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF
Heart failure with preserved ejection fraction (HFpEF) is a critical public health problem. Heart failure (HF) affects over 5 million adults in the United States (US), and is a major source of morbidity, mortality, and impaired…
- Trial name
- BLOCK HFpEF (NCT04434664)
- Testing
- Amlodipine Besylate, Metoprolol Succinate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Ischemic Heart Failure, Chronic Heart Failure
Allogeneic iPSC-derived Cardiomyocyte Therapy in Patients With Worsening Ischemic Heart Failure
This study is designed to evaluate the safety and efficacy of allogeneic induced pluripotent cell derived cardiomyocytes (iPSC-CMs) in treating patients with worsening ischemic heart failure undergoing coronary artery bypass…
- Trial name
- NCT05566600
- Testing
- Human (allogeneic) iPS-cell-derived cardiomyocyte
- Where
- 2 sites in China
- Volunteers
- 32 people
- Sponsor
- HELP Therapeutics Co., Ltd.
Chronic Obstructive Pulmonary Disease, Heart Failure
Adjusting to Chronic Conditions Using Education, Support, and Skills
The current study seeks to test the effectiveness of a talk-therapy intervention designed to better meet the needs of chronically ill Veterans.
- Conditions
- Chronic Obstructive Pulmonary Disease, Heart Failure, Anxiety, Depression
- Trial name
- ACCESS (NCT01149772)
- Testing
- ACCESS
- Where
- 2 sites in United States
- Volunteers
- 302 people
- Sponsor
- VA Office of Research and Development
Chronic Heart Failure, Central Sleep Apnea
Nocturnal Oxygen Needs and Central Sleep Apnea in Patients With Chronic Heart Failure.
The aims of this study are to 1) determine the optimal levels of O2 flow which prevent nocturnal O2 desaturation while minimizing periods of hyperoxia during the course of nocturnal oxygen therapy (NOXT) in heart failure patients…
- Trial name
- HO2F (NCT03254212)
- Testing
- Titration of nocturnal oxygen needs to prevent desaturations
- Where
- 2 sites in Canada
- Volunteers
- 14 people
- Sponsor
- Laval University
Chronic Kidney Disease, Heart Failure With Preserved Ejection Fraction (HFPEF)
Optimised Cardiovascular and Renal Protection in Patients With Chronic Kidney Disease and Cardiovascular Disease
The goal of this clinical trial is to investigate whether care in a specialised Cardio-Renal Clinic can improve the health of people living with both cardiovascular disease and chronic kidney disease.
- Conditions
- Chronic Kidney Disease, Heart Failure With Preserved Ejection Fraction (HFPEF), Cardiovascular Diseases
- Trial name
- OPTICARE (NCT07835828)
- Testing
- Multidisciplinary Cardio-Renal Care
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Odense University Hospital
Obesity, Hypertension
A Study of the Effects of Eplerenone and Amlodipine on Blood Pressure and Basal Metabolic Rate in Obese Hypertensives
Obesity and hypertension are independent risks for congestive heart failure (CHF) and chronic kidney disease. In obesity induced hypertension, the most common cause of human essential hypertension, the potential importance of…
- Trial name
- NCT00825188
- Testing
- eplerenone, amlodipine, eplerenone, amlodipine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Mississippi Medical Center
Chronic Heart Failure
VitamIN D Treating patIents With Chronic heArT failurE
Despite recent advances and even when receiving optimal therapy, patients with chronic heart failure (CHF) suffer poor quality of life, with recurrent hospitalisations and persistent symptoms.
- Trial name
- VINDICATE (NCT01619891)
- Testing
- Vitamin D
- Where
- United Kingdom
- Volunteers
- 253 people
- Sponsor
- University of Leeds
Acute Heart Failure
First In Human Study of the Doraya Catheter for the Treatment of AHF Patients
Safety and performance evaluation of the Doraya catheter in patients admitted with AHF.
- Trial name
- NCT03234647
- Testing
- Doraya catheter
- Where
- 7 sites in Belgium, Israel and 1 more
- Volunteers
- 9 people
- Sponsor
- Revamp Medical Ltd.
Chronic Heart Failure
A Phase IIa Clinical Trial on TSG-01 in the Treatment of Chronic Heart Failure in Patients With Coronary Heart Disease.
The purpose of this study is to assess the safety, efficacy and optimal dose of TSG-01, an innovative drug with ginsenosides as its main components, in the treatment of patients with chronic heart failure(CHF).
- Trial name
- NCT04515290
- Testing
- TSG-01
- Where
- 5 sites in China
- Volunteers
- 85 people
- Sponsor
- Shanghai Hongyitang Biopharmaceutical Technology Co. Ltd.