Clinical trials: Constipation, completed
Chronic Constipation
Effects of Oral PEG 3350 on Electrolyte Balance
The study is to evaluate the influence of three different doses of PEG 3350 with or without electrolytes on the electrolyte balance in patient volunteers with confirmed chronic constipation.
- Trial name
- NCT00868985
- Testing
- PEG 3350 plus electrolytes, PEG 3350 without electrolytes
- Where
- Romania
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Norgine
Constipation
Phase 2 Study of MD-1100 Acetate Administered for 14 Days to Patients Meeting Criteria for Chronic Constipation
The purpose of this study is to determine the safety and gastrointestinal pharmacodynamics (stool frequency, stool consistency, stool ease of passage, stool completeness of evacuation) of MD-1100 acetate administered daily for 14…
- Trial name
- NCT00306748
- Testing
- MD-1100 Acetate
- Where
- 14 sites in United States
- Volunteers
- 40 people
- Sponsor
- Ironwood Pharmaceuticals, Inc.
Diarrhea, Constipation
Probiotics and Hospital Outcome in the Elderly
Probiotics have been shown to reduce the rate of diarrhea and constipation. The purpose of this study was to investigate if probiotics could improve outcome of hospitalized orthopedic elderly patients.
- Trial name
- PROAGE (NCT00794924)
- Testing
- VSL#3
- Volunteers
- 345 people
- Sponsor
- Kaplan-Harzfeld Medical Center
Constipation
Comparison of PEG Solutions With and Without Electrolytes in the Treatment of Constipation
The aim of the study is to show that new polyethylene glycol (PEG) solution without electrolytes is as effective in the treatment of constipation as PEG solution with electrolytes in the elderly institutionalized people.
- Trial name
- PEGorion (NCT00603681)
- Testing
- Polyethylene glycol 4000, Polyethylene glycol 4000 with electrolytes
- Where
- 10 sites in Finland
- Volunteers
- 67 people
- Sponsor
- Orion Corporation, Orion Pharma
Constipation
Assessment of Whole Gut Transit Time Using the SmartPill Capsule
Our null hypothesis states that the two techniques (Sitzmarks radioopaque markers and SmartPill) are equivalent and is demonstrated if the study population shows a correlation of 0.7 or higher.
- Trial name
- WholeGut (NCT00603707)
- Where
- 8 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- The SmartPill Corporation
Chronic Constipation
Effect of Chinese Herb on Chronic Constipation for Residents in Long-Term Care Units
The purpose of our study is to improve the problem of constipation and increase the quality of long-term care by the regimen of Chinese herb prescribed by professional doctors of Chinese medicine.
- Trial name
- NCT00354575
- Testing
- Chinese Herb: CCH1
- Where
- Taiwan
- Volunteers
- 168 people
- Sponsor
- National Taiwan University Hospital
Postoperative Constipation
Prevention of Constipation: Systematic Nursing Interventions to Reduce Postoperative Constipation After Thoracic Surgery
The purpose of the study is to reduce the incidence of postoperative constipation by systematic nurse assessment, interventions and evaluation, in the first month after thoracic surgery.
- Trial name
- NCT00364169
- Testing
- Degree of constipation
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Surgery, Constipation
Stapled Trans Anal Rectal Resection (STARR) for Outlet Obstruction: Functional and Morphological Outcome
This study compares pre- and postoperative (at 6 month) quality of life and pathomorphology of the pelvis (by MRI defecation) after a STARR procedure for outlet obstruction. Trial with surgical intervention
- Trial name
- NCT00521872
- Testing
- STARR Operation
- Where
- Switzerland
- Sponsor
- University of Zurich
Constipation
Efficacy and Safety Study of Prucalopride for the Treatment of Elderly Patients With Chronic Constipation
The purpose of this study is to determine whether prucalopride is safe and effective in the treatment of chronic constipation in elderly patients.
- Trial name
- NCT00487422
- Testing
- prucalopride
- Volunteers
- 303 people
- Sponsor
- Movetis
Constipation
A Trial in Healthy Volunteers, to Evaluate the Tolerability and Cardiac Safety of Prucalopride
An escalating dose of prucalopride up to a maximum of 20 mg was given once daily to 32 healthy volunteers to determine safety at the maximum tolerable dose or at 20 mg.
- Trial name
- NCT00488215
- Testing
- prucalopride
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Movetis
Constipation
Prucalopride in Patients With Chronic Idiopathic Constipation
The purpose of this study is to determine whether prucalopride is safe and effective in the treatment of chronic idiopathic constipation. Hypothesis: Prucalopride given at a dose of 1 mg o.d.
- Trial name
- NCT00575614
- Testing
- prucalopride
- Volunteers
- 87 people
- Sponsor
- Movetis
Chronic Constipation
Effect of Prucalopride in Patients With Severe Chronic Idiopathic Constipation
The purpose of this study is to determine whether prucalopride is safe and effective in patients with severe chronic constipation.
- Trial name
- NCT00576511
- Testing
- prucalopride
- Volunteers
- 53 people
- Sponsor
- Movetis
Constipation
Efficacy and Safety Study of the Effect of Dose-Titration of Prucalopride for The Treatment of Chronic Constipation
The purpose of this study is to determine the safety profile of 4 mg prucalopride in the treatment of chronic constipation.
- Trial name
- NCT00577018
- Testing
- Prucalopride
- Volunteers
- 755 people
- Sponsor
- Movetis
Constipation
Trial to Evaluate the Efficacy and Safety of R093877 in Patients With Chronic Idiopathic Constipation
The purpose of the study is to determine whether prucalopride is safe and effective in patients with chronic idiopathic constipation.
- Trial name
- NCT00596596
- Testing
- prucalopride, 2 mg prucalopride, 4 mg prucalopride
- Volunteers
- 313 people
- Sponsor
- Movetis
Constipation
Efficacy and Safety Study of Prucalopride for the Re-Treatment of Chronic Constipation
The purpose of this study is to determine whether prucalopride is safe and effective in the re-treatment of chronic constipation.
- Trial name
- NCT00598338
- Testing
- Prucalopride
- Volunteers
- 516 people
- Sponsor
- Movetis
Constipation
Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation
The purpose of this study is to determine which dose of prucalopride is safe and effective in patients with chronic idiopathic constipation.
- Trial name
- NCT00617513
- Testing
- Prucalopride
- Volunteers
- 174 people
- Sponsor
- Movetis
Constipation
Evaluation of the Safety and Tolerability of Prucalopride in Constipated Elderly Subjects Living in a Nursing Facility
The purpose of this study is to determine whether prucalopride is safe and effective in the treatment of constipation in elderly subjects living in a nursing facility.
- Trial name
- NCT00627692
- Testing
- Prucalopride
- Volunteers
- 100 people
- Sponsor
- Movetis
Constipation
Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation
The purpose of this study is to determine which dose of prucalopride is safe and effective in patients with chronic constipation.
- Trial name
- NCT00631813
- Testing
- Prucalopride
- Volunteers
- 253 people
- Sponsor
- Movetis
Chronic Constipation
An Open Single Centre Study To Assess Treatment of Chronic Constipation in Children
The purpose of this study was to evaluate the safety and efficacy of Movicol in the treatment of chronic constipation in children.
- Trial name
- NCT00403897
- Testing
- Polyethylene glycol 3350 Na bicarbonate NaCl KCl
- Where
- Australia
- Volunteers
- 81 people
- Sponsor
- Norgine
Cardiovascular Disease, Constipation
Dose-Response Study of Probiotic Bacteria BB-12 and CRL-431 in Healthy Young Adults
The purpose of the study was to investigate the dose-response effect of increasing doses of Bifidobacterium animalis ssp lactis (BB-12) and Lactobacillus paracasei ssp paracasei (CRL-431) on the immune response, blood lipids, gut…
- Trial name
- NCT00611299
- Testing
- BB-12 and CRL 431
- Where
- Denmark
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen