Clinical trials: Constipation, completed
Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction
Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction
RATIONALE: The use of endoscopy to place metal stents in the duodenum is less invasive than surgery for treating cancer-related duodenal obstruction and may have fewer side effects and improve recovery.
- Conditions
- Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction, Extrahepatic Bile Duct Cancer, Gastric Cancer
- Trial name
- NCT00004910
- Testing
- bowel obstruction management, quality-of-life assessment
- Where
- United States
- Sponsor
- Northwestern University
Chronic Constipation
Connective Tissue Manipulation Improves Symptoms and Quality of Life in Patients With Chronic Constipation
Connective tissue manipulation (CTM) is a manual reflex therapy, which increases intestinal motility by stimulating autonomic nervous system to re-balance the parasympathetic and sympathetic functions.
- Trial name
- NCT02321124
- Testing
- connective tissue manipulation, life style advice
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Irritable Bowel Syndrome With Constipation, Functional Constipation
Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C
LIN-MD-66 is a Phase 3 open-label study with 24 weeks (Functional Constipation participants) or 52 weeks (Irritable bowel syndrome with constipation participants) of linaclotide exposure that will enroll pediatric participants…
- Trial name
- NCT04166058
- Testing
- Irritable Bowel Syndrome with Constipation (IBS-C) participants (LIN-MD-63 and LIN-MD-64 completers), Functional Constipation (FC) participants (LIN-MD-62 and LIN-MD-64 completers)
- Where
- 72 sites in United States, Canada and 2 more
- Volunteers
- 381 people
- Sponsor
- AbbVie
Constipation
Phase 2 Study of MD-1100 Acetate Administered for 14 Days to Patients Meeting Criteria for Chronic Constipation
The purpose of this study is to determine the safety and gastrointestinal pharmacodynamics (stool frequency, stool consistency, stool ease of passage, stool completeness of evacuation) of MD-1100 acetate administered daily for 14…
- Trial name
- NCT00306748
- Testing
- MD-1100 Acetate
- Where
- 14 sites in United States
- Volunteers
- 40 people
- Sponsor
- Ironwood Pharmaceuticals, Inc.
Chronic Constipation
Acupuncture for Chronic Constipation
Since there have been few advances for constipation in laxative treatment in the last 50 years, this study is designed to evaluate the efficacy and safety of acupuncture for patients with chronic constipation based on the theory…
- Trial name
- NCT00746200
- Testing
- (electro)acupuncture
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Neoplasms, Constipation
Methylnaltrexone for Opioid-induced Constipation in Cancer Patients
The purpose of this study is to evaluate the efficacy of methylnaltrexone in relieving opioid-induced constipation in cancer patients at various stages of disease.
- Conditions
- Neoplasms, Constipation, Opioid-Related Disorders
- Trial name
- NCT01004393
- Testing
- Methylnaltrexone bromide
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Vermont
Constipation
Clinical Trial on Palliative Cancer Patients With Constipation
It is a double-blinded, randomized, placebo-controlled trial for advanced cancer patients with constipation. 60 patients will be randomly assigned to have individualized herbal intervention (treatment group) or placebo (control…
- Trial name
- NCT02795390
- Testing
- Chinese herbal medicine
- Where
- 3 sites in Hong Kong
- Volunteers
- 60 people
- Sponsor
- Hong Kong Baptist University
Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction
Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction
RATIONALE: The use of endoscopy to place a metal stent in the large intestine is less invasive than surgery for treating cancer-related bowel obstruction and may have fewer side effects and improve recovery.
- Conditions
- Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction, Gastric Cancer, Gastrointestinal Carcinoid Tumor
- Trial name
- NCT00004911
- Testing
- bowel obstruction management, quality-of-life assessment
- Where
- United States
- Sponsor
- Northwestern University
Constipation
Abdominal Massage With TENS on Parasacral Versus Sacral Area on Symptom,Severity & QOL in Chronic Constipation Females.
Constipation is Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders…
- Trial name
- NCT06303011
- Testing
- Transcutaneous Electrical Nerve Stimulator, TENS on para sacral area with Abdominal Massage
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Constipation Chronic Idiopathic
Evaluation of the Triple Management Program in the Management of Functional Chronic Constipation in Children
Abstract Background: Chronic constipation is a common disease in children, 3% all children visit gastroenterology clinics with different types and complains.
- Trial name
- NCT06082622
- Testing
- laxatives
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Minia University
Spinal Cord Injuries, Traditional Chinese Medicine
Effect of Acupressure on Constipation in Community-dwelling Spinal Cord Injury Patients: a Randomized Controlled Trial
Spinal cord injury is a multi-sensory, motor and autonomic dysfunction, caused by various types of acute and chronic central nervous system injuries. And it will affect patient's ability to live normally and return to society.
- Trial name
- NCT05558657
- Testing
- Home-based, acupressure combined with nursing education, Home-based, manual light touch of the abdomen combined with nursing education
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- The Hong Kong Polytechnic University
Constipation, Diabetes
The Effectiveness of Lubiprostone in Constipated Diabetics
The investigators will recruit a total of 136 diabetic men and women with constipation into this study from both The Emory Clinic and The Atlanta Veteran's Administration Hospital.
- Trial name
- NCT01170039
- Testing
- Lubiprostone
- Where
- 2 sites in United States
- Volunteers
- 121 people
- Sponsor
- Emory University
MASSAGE
Investigation of the Effect of Abdominal Massage Applied to Palliative Care Patients on Constipation and Quality of Life
The problem of constipation plays a very important role among these symptoms that patients experience intensely and negatively affect their quality of life.
- Trial name
- NCT05742672
- Testing
- ABDOMINAL MASSAGE APPLICATION
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Constipation
The Function of Gastrointestinal Tract During Pregnancy
In this prospective study the function of gastrointestinal tract was assessed using constipation questionnaire (Rome criteria and bowel function index).
- Trial name
- umpiraskaus (NCT02577471)
- Where
- Finland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Constipation
A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adolescent Subjects
The objective of this study is to evaluate the safety and efficacy of BLI400 laxative in constipated adolescent subjects.
- Trial name
- NCT02665728
- Testing
- BLI400 Laxative
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Braintree Laboratories
Constipation
Effect of L. Reuteri on Bowel Movements in Children (BIOWELL Study)
A randomized, multicenter, placebo-controlled, double blind study in two parallel groups testing the efficacy of daily oral supplementation with the probiotic L.reuteri DSM17938 compared to placebo in increasing the number of…
- Trial name
- BIOWELL (NCT03030664)
- Testing
- L.reuteri
- Where
- 5 sites in France
- Volunteers
- 52 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Irritable Bowel Syndrome
Phase 2 Study of MD-1100 Acetate on Gastrointestinal Transit in Patients With C-IBS
The primary objective of this trial is to compare the dose-ranging pharmacodynamic effects of orally administered placebo, and 100 and 1000 ug qd of MD-1100 Acetate on gastrointestinal transit in patients with C-IBS.
- Trial name
- NCT00258193
- Testing
- MD-1100 Acetate
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Ironwood Pharmaceuticals, Inc.
Constipation
The Efficacy and Safety Study of Electro-acupuncture for Severe Chronic Functional Constipation
The main purpose of this study is to evaluate efficacy of electro-acupuncture for severe functional constipation compared with sham acupuncture, used as placebo; the secondary purpose is to evaluate the safety and post-treatment…
- Trial name
- NCT01726504
- Testing
- electro-acupuncture
- Where
- China
- Volunteers
- 1,075 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Chronic Pain, Opioid Induced Constipation
Naloxone SR Capsules in Patients With Opioid Induced Constipation
For many patients taking opioids for pain relief one of the most distressing side effects is constipation. Naloxone is effective in the reversal of the effects of opioids and is used following opioid overdose.
- Trial name
- NCT00984334
- Testing
- Naloxone SR 5 mg capsules, Naloxone SR 10 mg capsules, Naloxone SR 20mg capsules
- Where
- 8 sites in Germany, United Kingdom
- Volunteers
- 40 people
- Sponsor
- S.L.A. Pharma AG
Anal Incontinence or Constipation
Does Body Position Influence Pressure Recording by High-resolution Manometry ?
The anorectal manometry is the gold standard in the evaluation of anorectal function. Several techniques are currently used (balloons, perfused catheters) and are always performed in the supine position.
- Trial name
- NCT01946334
- Testing
- anorectal manometry and high-resolution three-dimensional
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille