Clinical trials: Constipation, completed
Constipation
Single Dose Pharmacokinetics of Prucalopride in Paediatric Subjects, With Functional Faecal Retention
The purpose of this study is characterize the pharmacokinetics of a single oral dose of 0.03 mg/kg prucalopride in paediatric subjects aged >= 4 to <= 12 years with functional faecal retention.
- Trial name
- NCT01674166
- Testing
- prucalopride
- Volunteers
- 38 people
- Sponsor
- Movetis
Constipation
Fiber Regimens for Constipation Symptoms
The objective of the current study is to compare the effects of bowel recipe with psyllium on symptoms associated with constipation.
- Trial name
- constipation (NCT03845673)
- Testing
- Psyllium, Bowel recipe
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Constipation - Functional
Lubiprostone in Children With Functional Constipation
Study to determine if children (6-17 years old) with functional constipation will respond to being treated with lubiprostone for 12 weeks.
- Trial name
- NCT02042183
- Testing
- Lubiprostone
- Where
- 117 sites in United States, Belgium and 5 more
- Volunteers
- 606 people
- Sponsor
- Sucampo Pharma Americas, LLC
MASSAGE
Investigation of the Effect of Abdominal Massage Applied to Palliative Care Patients on Constipation and Quality of Life
The problem of constipation plays a very important role among these symptoms that patients experience intensely and negatively affect their quality of life.
- Trial name
- NCT05742672
- Testing
- ABDOMINAL MASSAGE APPLICATION
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
IBS, IBS - Irritable Bowel Syndrome
Effect of Tenapanor on the Metagenomics and Metabolomics of Patients With Irritable Bowel Syndrome With Constipation
The aim of this study is to better understand how tenapanor affects the metagenomics and metabolomics of patients with irritable bowel syndrome with constipation (IBS-C). Tenapanor is the newest FDA-approved agent for IBS-C.
- Trial name
- NCT05995899
- Testing
- Tenapanor
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kyle Staller, MD, MPH
Constipation
Efficacy and Safety Study of Prucalopride to Treat Chronic Constipation
The purpose of this study is to determine whether prucalopride is safe and effective in the treatment of chronic constipation. Hypothesis: Prucalopride 2 mg and 4 mg given once daily for 12 weeks is superior to placebo for the…
- Trial name
- NCT00488137
- Testing
- Prucalopride
- Volunteers
- 716 people
- Sponsor
- Movetis
Irritable Bowel Syndrome With Constipation
Electro-acupuncture for Irritable Bowel Syndrome With Constipation
The aim of the clinical trial is to evaluate the efficacy and safety of electro-acupuncture for irritable bowel syndrome with constipation (IBS-C) patients.
- Trial name
- NCT06219707
- Testing
- Acupuncture needles
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Irritable Bowel Syndrome With Constipation, Irritable Bowel Syndrome
A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of DDP733 for IBS-c
This study will evaluate the safety, tolerability and pharmacodynamics of the investigational drug DDP733 in treating subjects with IBS-c. A placebo control will be utilized.
- Trial name
- NCT00215566
- Testing
- DDP733
- Where
- 15 sites in Canada
- Volunteers
- 90 people
- Sponsor
- Dynogen Pharmaceuticals
Constipation
Extended Use of Polyethyleneglycol3350 Laxative in Constipated Patients
To evaluate the safety and efficacy of extended use of polyethyleneglycol3350 laxative as compared to placebo in constipated patients.
- Trial name
- NCT00153153
- Testing
- polyethyleneglycol3350
- Where
- 45 sites in United States
- Volunteers
- 300 people
- Sponsor
- Braintree Laboratories
Functional Constipation
Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation
A randomized, double-blind/open-label, placebo/active-controlled, single/multiple dose, parallel, phase 1/2a trial to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of YH12852 in healthy subjects and…
- Trial name
- NCT02538367
- Testing
- YH12852 IR 0.05mg, YH12852 IR 0.1mg, YH12852 IR 0.3mg
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Gut Function, Occasional Constipation
Probiotic Intervention for Occasional Constipation
The goal of this clinical trial is to study the effect of probiotics on gut function in subjects with occasional constipation. The main question it aim to answer is if intake of probiotics will decrease the transit time.
- Trial name
- NCT06444139
- Testing
- Probiotics
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Probi AB
Chronic Idiopathic Constipation
A Exploratory Study of KWA-0711 in Patients With Chronic Idiopathic Constipation (CIC)
The purpose of this study is to evaluate the efficacy and safety of KWA-0711 in Chronic Idiopathic Constipation (CIC) patients.
- Trial name
- NCT01600001
- Testing
- KWA-0711
- Where
- Japan
- Volunteers
- 75 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Chronic Constipation
Study to Examine the Efficacy and Safety of Movicol in the Treatment of Chronic Constipation in Children
A phase III, multi-centre, double blind, placebo controlled, crossover study, followed by an open label post study follow-up, to assess the efficacy and safety of Movicol in the treatment of chronic constipation in children
- Trial name
- NCT00403819
- Testing
- Polyethylene glycol 3350 Na bicarbonate NaCl KCl (Movicol)
- Where
- 6 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Norgine
Constipation, Distention
Determining the Effect of Breathing Exercise Applied to Children Aged 6-12 Before Enema on Anxiety, Fear and Pain
In this study, it was aimed to determine the effect of breathing exercise applied before the enema procedure, which causes fear, pain and anxiety in children aged 6-12 years who applied to the pediatric emergency service, on…
- Conditions
- Constipation, Distention, Child, Only
- Trial name
- NCT05508022
- Testing
- Breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Chronic Constipation
Connective Tissue Manipulation Improves Symptoms and Quality of Life in Patients With Chronic Constipation
Connective tissue manipulation (CTM) is a manual reflex therapy, which increases intestinal motility by stimulating autonomic nervous system to re-balance the parasympathetic and sympathetic functions.
- Trial name
- NCT02321124
- Testing
- connective tissue manipulation, life style advice
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Postoperative Constipation
Prevention of Constipation: Systematic Nursing Interventions to Reduce Postoperative Constipation After Thoracic Surgery
The purpose of the study is to reduce the incidence of postoperative constipation by systematic nurse assessment, interventions and evaluation, in the first month after thoracic surgery.
- Trial name
- NCT00364169
- Testing
- Degree of constipation
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Constipation
The Incidence, Risk Factors, and Effects of Constipation in Critical Patients
This study aimed to investigate the early, late, and total constipation frequency, related factors, and their effects on the hospitalization day, gastric residual volume, vomiting, distension, and diarrhea, the feeding type…
- Trial name
- NCT05683743
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Abant Izzet Baysal University
Constipation
Clinical Trial on Palliative Cancer Patients With Constipation
It is a double-blinded, randomized, placebo-controlled trial for advanced cancer patients with constipation. 60 patients will be randomly assigned to have individualized herbal intervention (treatment group) or placebo (control…
- Trial name
- NCT02795390
- Testing
- Chinese herbal medicine
- Where
- 3 sites in Hong Kong
- Volunteers
- 60 people
- Sponsor
- Hong Kong Baptist University
Constipation
Safety and Tolerability of Oral Polyethylene Glycol (PEG 3350) Solution in Participants With Constipation (MK-8114-003)
The purpose of this study is to compare the safety and tolerability of oral ingestion of PEG 3350 solution concentrate to oral ingestion of a placebo solution concentrate, in participants with constipation.
- Trial name
- NCT01885104
- Testing
- Polyethylene Glycol (PEG 3350), Bisacodyl laxative tablets (rescue medication)
- Volunteers
- 65 people
- Sponsor
- Bayer
Bladder Dysfunction, Bowel Dysfunction
Comparison of Transcutaneous Electrical Nerve Stimulation and Manual Therapy in Children With Cerebral Palsy
There are many studies in the literature on healthy children with lower urinary tract dysfunction (LUTD), but there are limited number of studies in children with cerebral palsy (CP) with LUTD.
- Conditions
- Bladder Dysfunction, Bowel Dysfunction, Cerebral Palsy, Neurogenic Bladder
- Trial name
- NCT05351138
- Testing
- TENS, Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Bahçeşehir University