Clinical trials: Constipation - Functional
Functional Constipation
Effect of Lactobacillus Gasseri DSM 27123 on Functional Constipation in Healthy Women
The primary objective is to determine the change in frequency of complete spontaneous bowel movements (CSBMs) after 4 weeks of oral supplementation with Lactobacillus gasseri DSM 27123 in healthy adult women with functional…
- Trial name
- NCT02592200
- Testing
- Lactobacillus gasseri DSM 27123
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Irritable Bowel Syndrome With Constipation, Functional Constipation
IBS-C Questionnaire Study
The study is a multi-centre, observational study which enrolls 150 IBS-C patients and 150 non-IBS-C patients in China.
- Trial name
- NCT04968652
- Where
- 10 sites in China
- Volunteers
- 300 people
- Sponsor
- AstraZeneca
IBS, Constipation Predominant
The Beneficial Effects on the Intestinal Function of a Food Supplement Based on an Extract of Green Tea and a Pool of Probiotics in Subjects With Irritable Bowel Syndrome With Predominance of Constipation
The study will aim to evaluate the effectiveness of the use of a food supplement, based on a green tea extract (Camellia sinensis (L.) Kuntze - folium) and a pool of probiotics (L. plantarum, L. rhamnosus and B. animalis subsp.
- Trial name
- NCT07094035
- Testing
- food supplement based on a mixture of green tea extract and a pool of probiotics.
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Adamas Biotech S.r.l.
Irritable Bowel Syndrome, Irritable Bowel Syndrome - Constipation
GOS to Reduce Symptom Severity in IBS
IBS is a highly prevalent bowel disorder, characterized by recurrent abdominal pain during bowel movements or a change in bowel habits.
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome - Constipation, Irritable Bowel Syndrome - Diarrhoea, Irritable Bowel Syndrome - Mixed
- Trial name
- EGIS (NCT05157061)
- Testing
- Galacto-oligosaccharides (GOS), Maltodextrine
- Where
- 9 sites in Belgium, Netherlands and 1 more
- Volunteers
- 153 people
- Sponsor
- Clasado
Functional Constipation (FC), Chronic Idiopathic Constipation (CIC)
A Study to Assess Adverse Events and Change in Symptoms With Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation
Functional constipation (FC) is a common healthcare problem in children of all ages, potentially due to genetic predisposition, inadequate fiber and fluid intake, and immobility.
- Trial name
- NCT05652205
- Testing
- Linaclotide
- Where
- 48 sites in United States, Bulgaria and 2 more
- Volunteers
- 123 people
- Sponsor
- AbbVie
Functional Constipation, Irritable Bowel Syndrome With Constipation
Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)
The objective of LIN-MD-64 is to evaluate the safety and efficacy of 12 weeks of linaclotide therapy (72 μg daily) in comparison with placebo in pediatric participants, 6 to 17 years of age, who fulfill modified Rome III Criteria…
- Trial name
- NCT04026113
- Testing
- Linaclotide
- Where
- 115 sites in United States, Belgium and 12 more
- Volunteers
- 438 people
- Sponsor
- AbbVie
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Fecal Calprotectin Collection Protocol
The primary objective is to obtain stool samples from subjects diagnosed with , and displaying signs and/or symptoms of IBD and/or IBS will be evaluated in this study.
- Conditions
- Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Ulcerative Colitis, Crohn Disease
- Trial name
- CALFE (NCT03143517)
- Testing
- Stool collection
- Where
- 13 sites in United States
- Volunteers
- 240 people
- Sponsor
- DiaSorin Inc.
Functional Constipation (FC)
The Beneficial Effect on the Bowel Function of a Food Supplement Based on Sea Buckthorn (Hippophae Rhamnoides L.) Extract in Subjects With Primary Functional Constipation
The study will aim to evaluate the efficacy and tolerability of a supplementation with Sea Buckthorn (Hippophae rhamnoides L.) at two different dosages for the management of the balance of intestinal function in subjects with…
- Trial name
- NCT07082673
- Testing
- Sea Buckthorn (Hippophae rhamnoides L.) botanical extract 500 mg., Sea buckthorn (Hippophae rhamnoides L.) 1500 mg.
- Where
- Italy
- Volunteers
- 135 people
- Sponsor
- ISTITUTO FARMOCHIMICO FITOTERAPICO: EPO SRL
Functional Constipation
Study of NGM282 in Subjects With Functional Constipation and Healthy Individuals
The purpose of this study is to determine the effect of NGM282 on colonic transit, bile acid homeostasis, and fecal fat in subjects with functional constipation and healthy individuals.
- Trial name
- NCT02649062
- Testing
- NGM282
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- NGM Biopharmaceuticals, Inc