Clinical trials: Constipation Chronic Idiopathic
Constipation, Chronic Idiopathic Constipation
An Open Label Study of Chronic Use of BLI400 Laxative in Constipated Adults
The objective of this study is to evaluate the safety of chronic use of BLI400 laxative in constipated adults.
- Conditions
- Constipation, Chronic Idiopathic Constipation, CIC
- Trial name
- NCT02819310
- Testing
- BLI400 Laxative
- Where
- 24 sites in United States
- Volunteers
- 330 people
- Sponsor
- Braintree Laboratories
Constipation
Trial to Evaluate the Efficacy and Safety of R093877 in Patients With Chronic Idiopathic Constipation
The purpose of the study is to determine whether prucalopride is safe and effective in patients with chronic idiopathic constipation.
- Trial name
- NCT00596596
- Testing
- prucalopride, 2 mg prucalopride, 4 mg prucalopride
- Volunteers
- 313 people
- Sponsor
- Movetis
Chronic Idiopathic Constipation
12-Week Study of Plecanatide for CIC (The CIC3 Study)
The purpose of this study is to confirm that the investigational medication, plecanatide, is safe and effective in treating chronic idiopathic constipation.
- Trial name
- NCT01982240
- Testing
- Plecanatide, Bisacodyl
- Where
- 189 sites in United States, Canada
- Volunteers
- 1,394 people
- Sponsor
- Bausch Health Americas, Inc.
Chronic Idiopathic Constipation
Open-label Extension (OLE) Study of Plecanatide for Chronic Idiopathic Constipation (CIC)
This is a multi-center, open-label, 52-week safety and tolerability study of plecanatide in patients with Chronic Idiopathic Constipation (CIC).
- Trial name
- NCT01919697
- Testing
- Plecanatide
- Where
- 220 sites in United States, Canada
- Volunteers
- 2,370 people
- Sponsor
- Bausch Health Americas, Inc.
Constipation, Chronic Constipation
Study of Elobixibat (A3309) in Patients With Chronic Idiopathic Constipation
The purpose of this trial is to determine the efficacy and safety of A3309 administered to patients with chronic idiopathic constipation.
- Trial name
- ACCESS (NCT01007123)
- Testing
- A3309
- Where
- 44 sites in United States
- Volunteers
- 190 people
- Sponsor
- Albireo
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Gastroparesis, GERD
Domperidone for Relief of Gastrointestinal Disorders
The purpose of this study is to make Domperidone available to patients with gastrointestinal disorders who have failed standard therapy and who might benefit from it.
- Conditions
- Gastroparesis, GERD, Esophagitis, Dyspepsia
- Trial name
- NCT00761254
- Testing
- Domperidone
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Carle Physician Group
Fecal Incontinence and Constipation
Sacral Nerve Stimulation for Anal Incontinence and Bowel Control
Multicenter European study to evaluate efficacy and safety of sacral nerve stimulation with InterStim Therapy to treat fecal incontinence or constipation
- Trial name
- MDT-301 (NCT00200005)
- Testing
- Type: Implantable neurostimulator; InterStim
- Where
- 9 sites in United States, Austria and 6 more
- Volunteers
- 140 people
- Sponsor
- MedtronicNeuro
Chronic Idiopathic Constipation, Irritable Bowel Syndrome (IBS-C)
"Efficacy and Safety of Linaclotide in Chronic Constipation"
Goal of this study is to evaluate the efficacy and safety of two different doses of Linaclotide in improving bowel function and patient-reported outcomes among Bangladeshi patients with chronic constipation for 8 weeks along with…
- Conditions
- Chronic Idiopathic Constipation, Irritable Bowel Syndrome (IBS-C), Chronic Constipation, CIC
- Trial name
- LIN-CC-BD (NCT07431957)
- Testing
- Linaclotide 72 micrograms, Linaclotide 145 micrograms
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Md Mehedi Shahriar
Chronic Idiopathic Constipation (CIC)
Post-Marketing Study of Prucalopride Safety In Pregnancy
This study collects information on pregnant women with ongoing constipation who took prucalopride and those who did not take prucalopride.
- Trial name
- NCT04869280
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Takeda
Constipation and Dyspepsia
The Effects of Tegaserod vs. Placebo on Whole Gut Transit Time in Patients With Chronic Constipation and Dyspepsia
To demonstrate the effects of tegaserod on gastrointestinal scintigraphic orocecal transit in female patients with CC and upper GI symptoms of dyspepsia
- Trial name
- NCT00277550
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novartis
Chronic Idiopathic Constipation
Evaluation of Clinical Equivalence Between Two Lubiprostone Products
The objective of this study is to evaluate the clinical equivalence and safety of the Test formulation of lubiprostone 24 mcg capsules compared to the marketed formulation AMITIZA® (lubiprostone) 24 mcg capsules (Sucampo…
- Trial name
- NCT01372423
- Testing
- Lubiprostone
- Where
- 79 sites in United States
- Volunteers
- 808 people
- Sponsor
- Anchen Pharmaceuticals, Inc
Chronic Idiopathic Constipation
A Multicenter, Double-Blind, Randomized, Placebo-Controlled, 12-Week, Dose-Range-Finding Trial of YKP10811 Capsules Administered Once Daily to Subjects With Chronic Idiopathic Constipation
This will be a multi-center, randomized, double-blind, placebo-controlled study of YKP10811 capsules in patients with chronic idiopathic constipation.
- Trial name
- NCT01989234
- Testing
- YKP10811
- Where
- 69 sites in United States
- Volunteers
- 334 people
- Sponsor
- SK Life Science, Inc.
Constipation
Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation
The purpose of this study is to determine which dose of prucalopride is safe and effective in patients with chronic constipation.
- Trial name
- NCT00631813
- Testing
- Prucalopride
- Volunteers
- 253 people
- Sponsor
- Movetis
Chronic Idiopathic Constipation
SP-304 Dose Ranging Study in Patients With Chronic Idiopathic Constipation
This is a Phase 2a, randomized, double-blind, placebo-controlled, 14-day repeat oral, dose ranging study to determine the safety, pharmacokinetics (PK) and pharmacodynamics (PD) effects of SP-304 in patients with chronic…
- Trial name
- CIC (NCT01053962)
- Testing
- SP-304 0.3 mg, SP-304 1.0 mg, SP-304 3.0 mg
- Where
- 14 sites in United States
- Volunteers
- 84 people
- Sponsor
- Bausch Health Americas, Inc.
Functional Constipation (FC)
This is a Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel-group Study of the Efficacy and Safety of 2 Weight-based Treatment Groups of Plecanatide Versus Placebo in Children and Adolescent Participants 6 to Less Than 18 Years of Age With FC
The goal of this clinical trial is to learn if plecanatide can treat functional constipation in children and adolescents aged 6 to less than 18 years.
- Trial name
- Trulance (NCT07723924)
- Testing
- plecanatide
- Where
- 29 sites in United States
- Volunteers
- 180 people
- Sponsor
- Bausch Health Americas, Inc.
Constipation Chronic Idiopathic
Efficacy of a Dietary Intervention for the Treatment of Constipation in Institutionalized Older Adults. Medellín, 2023-2024.
The objective of this clinical trial is to determine if a dietary intervention for the treatment of chronic idiopathic constipation in older adults in the city of Medellin is effective (works well), focusing on the population in…
- Trial name
- NCT05923723
- Testing
- FIBNUTRITION
- Where
- 2 sites in Colombia
- Volunteers
- 56 people
- Sponsor
- CES University
Pediatric Functional Constipation
ROLE OF PELVIC ULTRASOUND IN THE TREATMENT MONITORING OF CHILDREN WITH CHRONIC Idiopathic Constipation
Constipation is a frequently encountered problem in childhood, with a prevalence ranging between 1 and 30%. Several studies have proposed pelvic ultrasound, (simple, non-invasive and reproducible) both to define the presence of…
- Trial name
- NCT05787093
- Testing
- transabdominal rectal ultrasound
- Where
- Italy
- Volunteers
- 123 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Idiopathic Constipation
A Postmarketing Study of Plecanatide in Breast Milk of Lactating Women Treated With TRULANCE®
This is a multi-center, open-label study evaluating pharmacokinetics of TRULANCE® (plecanatide) in breast milk of lactating women treated with TRULANCE
- Trial name
- NCT03551873
- Testing
- Plecanatide
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Bausch Health Americas, Inc.
Irritable Bowel Syndrome With Constipation, Chronic Idiopathic Constipation
A Treatment Investigational New Drug (tIND) Program of Tegaserod in Women With Irritable Bowel Syndrome With Constipation or With Chronic Idiopathic Constipation
To provide tegaserod to eligible women adult patients who did not have satisfactory improvement of their irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC) symptoms with other available…
- Trial name
- NCT00511771
- Testing
- Tegaserod
- Sponsor
- Novartis