Clinical trials: Consumption, Tobacco
Tobacco Dependence
Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence
The purpose of this study is to test the safety, tolerability, compliance and efficacy of two different forms of nicotine replacement therapy (NRT) (the nicotine transdermal patch and the nicotine gum) in a nicotine-dependent…
- Trial name
- NCT01208935
- Testing
- Nicotine Patch, Nicotine Gum
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Nicotine Addiction, Smoking Cessation
Evaluation of a Smoking Cessation Program for Long-Term Abstinence
This observational study evaluates a structured smoking cessation program delivered via weekly group sessions. The primary objective is to assess participant-reported smoking abstinence following completion of the program and at…
- Trial name
- ESCaPe (NCT06746025)
- Testing
- Quit Center cessation program
- Where
- United States
- Volunteers
- 371 people
- Sponsor
- Quit Center LLC
Smoking Cessation, Food Insecurity
An Intervention to Promote Smoking Cessation Among Adults With Food Insecurity
This is a two-arm randomized controlled study with 60 participants. The study has two aims. The first aim is to determine the feasibility and acceptability of a food assistance intervention to alleviate food insecurity during a…
- Trial name
- NCT05259852
- Testing
- Food Assistance and Cessation Resources Navigation Plus Economic Assistance, Food Assistance and Cessation Resources Navigation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Case Western Reserve University
Tobacco Use
A Study to Evaluate Changes in Smokers Using Oral Tobacco-derived Nicotine Products.
The purpose of this study is to evaluate changes in exposure to selected harmful and potentially harmful constituents (HPHC) by measuring biomarkers in adult smokers who partially or completely switch from smoking cigarettes to…
- Trial name
- NCT03692078
- Testing
- OTDN product 1, OTDN product 2, Tobacco Cessation
- Where
- 2 sites in United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Altria Client Services LLC
Tobacco Use Disorder, Smoking Cessation
Tobacco Treatment Medical Education in 10 Medical Schools
This study compares two methods of teaching the 5As (Ask, Advise, Assess, Assist, Arrange) for tobacco dependence treatment to medical students: 1) traditional medical education (TE), and 2) multi-modal education (MME).
- Trial name
- MSQuit (NCT01905618)
- Testing
- Web-based curriculum on tobacco dependence treatment, Tobacco Counseling Role Play, Preceptor Training and Teaching Medical Students
- Where
- 13 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Massachusetts, Worcester
Tobacco Dependence, Veterans
Identifying Effective Treatment for Veterans Unwilling to Quit Smoking
This project will generate knowledge about the effectiveness of Enhanced Chronic Care, an intervention designed to enhance treatment use and smoking abstinence in Veterans who are initially unwilling to quit.
- Trial name
- NCT04061720
- Testing
- Enhanced Chronic Care, Standard Care
- Where
- United States
- Volunteers
- 502 people
- Sponsor
- VA Office of Research and Development
Tobacco Dependence
Prolonged Smoking Cessation Using Prescription Step Care
Smoking is the number one preventable cause of morbidity and mortality in this nation. Unfortunately, more than 50% of those who quit following a smoking cessation intervention typically relapse within two weeks, with…
- Trial name
- NCT00170079
- Testing
- Smoking Cessation Intervention
- Where
- 2 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Smoking, E-cigarette Use
Impact of New Product Standards for JUUL Among Dual JUUL/Combusted Cigarette Users
To date the majority of experimental tobacco regulatory science has focused specifically on the impact of possible tobacco product standards (e.g.
- Conditions
- Smoking, E-cigarette Use, Cigarette Smoking
- Trial name
- NCT04179617
- Testing
- 5% nicotine content JUUL pod, 3% nicotine content JUUL pod
- Sponsor
- Duke University
Tobacco Cessation, HIV
Tobacco Assessment and Intervention With Low-Income Persons Living With HIV-AIDS (PLWHA) in Community-Based AIDS Service Organizations
"A treatment session especially for PLWHA to help them discuss and take action about their smoking may be useful."
- Conditions
- Tobacco Cessation, HIV, AIDS
- Trial name
- NCT01482923
- Testing
- Treatment as usual, AIR (Aspirations, Inspiration, Respiration)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Smoking, Tobacco Use
CSD201004: An Actual Use Study of P10 and P13 Nicotine Pouches Among U.S. Adult Smokers
The purpose of this Actual Use Study (AUS) is to investigate how U.S. adult tobacco consumers 21-60 years of age) who are regular smokers (≥5 cigarettes/day) on at least 20 days out of the past 30 days will use P10 and P13…
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Trial name
- NCT05184920
- Testing
- P1012919 nicotine pouch, P1012915 nicotine pouch, P1012914 nicotine pouch
- Where
- 10 sites in United States
- Volunteers
- 1,105 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Smoking, Tobacco Smoking
Pilot Study of Contingency Management for Smoking Cessation
The purpose of this study is to see whether contingency management (CM) can be successfully added as an adjunct treatment to standard stop smoking services in outpatients undergoing treatment for opiate addiction.
- Conditions
- Smoking, Tobacco Smoking, Smoking, Tobacco, Smoking Cessation
- Trial name
- NCT03015597
- Testing
- Contingency Management
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- King's College London
Lung Cancer
Lung Cancer Screening Implementation Among Employees at Lyon Hospital
Several randomized studies have demonstrated the efficiency of lung cancer screening (LCS) on mortality rates. However, screening efficiency is related to the targeted population and the participation rate.
- Trial name
- ILYAD (NCT05452200)
- Testing
- Solicitation for lung cancer screening, added exams to the usual lung cancer screening
- Where
- 3 sites in France
- Volunteers
- 600 people
- Sponsor
- Hospices Civils de Lyon
Smoking, Tobacco Use
Linking Brain Network Dynamics to Imminent Smoking Lapse Risk and Behavior
Most attempts to quit smoking end in relapse, or a return to regular smoking. One of the biggest threats to cessation is a lapse (i.e., any cigarette use during a quit attempt).
- Trial name
- NCT05572671
- Testing
- Laboratory task modeling smoking lapse behavior
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Penn State University
Chronic Pain, Tobacco Use
Opioids, Low Nicotine Cigarettes, and Chronic Pain
The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on craving, withdrawal, and pain among individuals with chronic pain…
- Conditions
- Chronic Pain, Tobacco Use, Opioid Substitution Treatment
- Trial name
- NCT06747871
- Testing
- Very Low Nicotine Cigarettes (VLNC), Normal Nicotine Cigarettes (NNC)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Tobacco Use Disorder, Smoking Cessation
Deep rTMS and Varenicline for Smoking Cessation
The purpose of this study is to investigate the effect of deep repetitive transcranial magnetic stimulation (rTMS) using the insula H-coil on smoking outcomes in smokers receiving varenicline.
- Trial name
- NCT04083144
- Testing
- Deep Repetitive Transcranial Magnetic Stimulation (Active), Varenicline
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Dependence
Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study
Specific aims: 1. To obtain pilot data on 4-week continuous quit rates associated with 10 weeks of treatment with topiramate or placebo or topiramate plus nicotine patch for smoking cessation. 2.
- Trial name
- NCT00755716
- Testing
- Topiramate, Nicotine patch
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- UConn Health
Tobacco Dependence, COPD Asthma
Cytisine vs Nicotine Replacement Therapy
Tobacco is the most preventable cause of disease and death in Canada. Although the tobacco use rate has substantially gone down in the general population, significant differences exist between sub-populations in Canada, for…
- Conditions
- Tobacco Dependence, COPD Asthma, Mental Illness, Substance Use
- Trial name
- NCT03249428
- Testing
- Cytisine, Nicotine replacement therapy (NRT)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Tobacco Dependence
Project 1, Study 1: Investigating the Impact of Nicotine Using Spectrum Cigarettes
Project 1, Study 1 will evaluate the relationship between nicotine yield of very low nicotine content cigarettes and cigarettes smoked per day, nicotine exposure, discomfort/dysfunction, other health-related behaviors…
- Trial name
- P1S1 (NCT01681875)
- Testing
- very low nicotine content cigarettes
- Where
- 9 sites in United States
- Volunteers
- 839 people
- Sponsor
- Wake Forest University Health Sciences
Tobacco Use
Early Tobacco Abstinence - 5
This proposal will conduct a prospective examination of the clinical course (intensity, content and duration) of tobacco (nicotine) abstinence effects in male and female smokers who are either heavy/light alcohol drinkers…
- Trial name
- NCT00224965
- Testing
- Behavior Therapy
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Efficacy of Financial Incentives
Voucher Based Incentives to Treat Pregnant Smokers
The major goal of this project is to examine the efficacy of a voucher-based incentive program for promoting smoking cessation (Study 1) and preventing relapse (Study 2) during pregnancy and postpartum.
- Trial name
- NCT01801384
- Testing
- Voucher-based incentives
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- University of Vermont
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