Clinical trials: Consumption, Tobacco
Smoking
The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With Abstinence
This study will evaluate the compliance with a daily kava regimen among active smokers who have an intention to quit smoking. This study will also investigate whether kava use can facilitate tobacco cessation, reduce stress, and…
- Trial name
- NCT05814055
- Testing
- AB-free kava
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Florida
Smoking, Tobacco Use Disorder
QuitAdvisorMD: A Point-of-care Tool for Brief Smoking Cessation Interventions
QuitAdvisorMD: A point-of-care tool for brief smoking cessation interventions Under a Phase II SBIR grant supported by NIH/NIDA, we are developing QUITAdvisorMD: a point-of-care, patient-centered resource for counseling patients…
- Trial name
- NCT01065493
- Testing
- QuitAdvisorMD Software Algorithm, Standard Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Silverchair Science & Communications, LLC
Smokeless Tobacco Cessation
A Text-based Reduction Intervention for Smokeless Tobacco Cessation- Pilot Study
All participants will receive the EnufSnuff.TXT scheduled gradual reduction (SGR) intervention for 6 weeks and, for those who do not reach the point of quit, includes getting randomized (like the flip of a coin) into either an…
- Trial name
- NCT06637358
- Testing
- Extended Scheduled Gradual Reduction (SGR), Quit Coach
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Duke University
Tobacco Use Cessation
Optimizing the Tobacco Cessation Clinical Decision Support Tool.
The existing tobacco cessation best practice advisory (BPA) fires for providers (physicians, residents, fellows, midwives, nurse practitioners, physician assistants) during outpatient encounters when a patient is identified as a…
- Trial name
- NCT03714191
- Testing
- Patient Outcomes, Billing documentation, Regulatory
- Where
- United States
- Volunteers
- 54,417 people
- Sponsor
- NYU Langone Health
Cigarette Smoking
Pharmacogenetics of Nicotine Metabolism in African-Americans
The investigators hypothesize that African Americans (AAs) smoke more for positive reinforcement from nicotine with a "peak-seeking" pattern of smoking (smoking individual cigarettes more intensively with greater intake of…
- Trial name
- 5075-AAPK1 (NCT00879918)
- Testing
- Deuterated nicotine and cotinine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cigarette Smoking, Schizophrenia
rTMS Effects on Smoking Cessation and Cognition in Schizophrenia
Patients with schizophrenia have high rates of cigarette smoking and tobacco dependence, and great difficulties in quitting smoking.
- Trial name
- NCT00736710
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Centre for Addiction and Mental Health
Nicotine Dependence, Nicotine Dependence, Cigarettes
United States Pre-Market Tobacco Application Pharmacokinetics
A Randomized, Open-Label, Cross-Over Study to Assess Nicotine Uptake and Subjective Measures with Use of JUUL 5% Electronic Nicotine Delivery Systems (ENDS) Compared to Usual Brand Combustible Cigarettes, a Comparator…
- Conditions
- Nicotine Dependence, Nicotine Dependence, Cigarettes, Tobacco Use, Tobacco Smoking
- Trial name
- US-PMTA-PK (NCT03719391)
- Testing
- Virginia Tobacco flavored JUUL 5% ENDS, Cool Mint flavored JUUL 5% ENDS, Mango flavored JUUL 5% ENDS
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Smoking, Cigarette
FDA Cigarette Warning Labels: Eye Tracking Study
The purpose of this study is to examine the effect of cigarette pictorial warning label content (lesser-known vs well-known risks) on visual engagement, recall, and knowledge of tobacco use harms.
- Trial name
- FLT (NCT04936724)
- Testing
- Pictorial Warning Labels
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Cigarette Smoking, Nicotine Dependence
Nicotine Withdrawal and Reward Processing
This study is designed to find out how smoking affects the way the brain responds to pleasure and how this impacts smokers' behavior. Participants will complete three sessions.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Nicotine Withdrawal
- Trial name
- NicWith (NCT05041959)
- Testing
- Smoking Abstinence, Ad Lib Smoking
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Tobacco Dependence
A Bioequivalence Study Between Two Nicotine Replacement Therapies in Adult Healthy Smokers Motivated to Quit.
This is a research study to verify the same effectiveness and safety profile for the test product, Nicorette Strongmint lozenge, as for an already approved product, NiQuitin® Minimint lozenge (reference product), in a…
- Trial name
- NCT03130179
- Testing
- Nicorette Strongmint lozenge 4 mg, Niquitin MiniMint lozenge 4 mg
- Where
- Russia
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- McNeil AB
Smoking
Reducing Tobacco-associated Lung Cancer Risk: A Randomized Clinical Trial of AB-free Kava
Tobacco use is the leading cause of many preventable diseases, particularly lung cancer. Based on the national cancer data in 2020, Florida has the highest lung cancer incidence (18,150 cases) with the most deaths (10,580 deaths)…
- Trial name
- NCT05081882
- Testing
- Kava
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Florida
Smoking Cessation
Message Priming and Enrollment in, and Response to, a Smoking Cessation Program: A Pilot Study
The proposed study has been designed to examine the effect of a message that primes genetic susceptibility on actual enrollment in a smoking cessation program, actual response to smoking cessation treatment, and potential…
- Trial name
- NCT00596882
- Testing
- Message Prime
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Use
Mechanisms of Ethnic/Racial Differences in Lung Cancer Due to Cigarette Smoking Clinical and Biomarkers Core
The purpose of the study is to collect human biological samples and measurements from people of various ethnic and racial backgrounds for projects related to the "Mechanisms of Ethnic/Racial Differences in Lung Cancer Due to…
- Trial name
- NCT03352635
- Where
- 2 sites in United States
- Sponsor
- University of Minnesota
Tobacco Smoking
The SMOKE Telehealth Study
The goal of this clinical trial is to develop two health-focused interventions for tobacco smokers with chronic pain. The main questions it aims to answer are: Are the interventions feasible for delivery via telehealth? Are the…
- Trial name
- NCT07743710
- Testing
- Smoking and Health Telehealth Intervention 1, Smoking and Health Telehealth Intervention 2
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Binghamton University
Obesity, Sedentary Lifestyle
The Healthy Options Feasibility Study
The investigators hypothesize that having health care providers other than physicians within a "Groupe de Médecine de Famille" conduct cardiovascular risk assessments and teach lifestyle interventions to primary prevention…
- Conditions
- Obesity, Sedentary Lifestyle, Dyslipidemia, Hypertension
- Trial name
- NCT00746460
- Testing
- CVD risk profile
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University
Smoking Cessation, Tobacco Use Cessation
Safety and Effectiveness of NicVAX in Treating Nicotine Dependent Individuals
Nicotine is highly addictive and many individuals are unable to quit smoking even with treatment. The purpose of this study is to determine the effectiveness of various doses of NicVAX in treating nicotine dependent individuals.
- Trial name
- NCT00218413
- Testing
- NicVAX
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Nabi Biopharmaceuticals
Prescription Drug Abuse, Substance Abuse
A High School Program for Preventing Prescription Drug Misuse
This project will develop and evaluate a program to prevent prescription drug misuse in high school students
- Conditions
- Prescription Drug Abuse, Substance Abuse, Substance Use (Drugs, Alcohol)
- Trial name
- NCT03219190
- Testing
- LST High School Hybrid
- Where
- United States
- Volunteers
- 1,804 people, healthy volunteers welcome
- Sponsor
- National Health Promotion Associates, Inc.
Smokeless Tobacco, Nicotine Dependence
Treating Smokeless Tobacco Use in Rural Veterans
This is a pilot study designed in an effort to develop and improve access to effective treatments for tobacco use in rural Veterans using a tailored intervention approach.
- Trial name
- NCT02994082
- Testing
- Tailored behavioral intervention, Behavioral activation for elevated depressive symptoms, Post-cessation weight gain management
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Mark Vander Weg
Tobacco Smoking
Tobacco and Socioeconomic Disadvantage
Randomized clinical trial comparing 3 brief interventions designed to increase motivation to quit smoking in socioeconomically disadvantaged smokers.
- Trial name
- NCT03620708
- Testing
- Motivational Interviewing, Nicotine Replacement Therapy Sampling, Referral Only
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Nicotine Dependence
Baclofen Effects in Cigarette Smokers
The proposed project will utilize perfusion functional magnetic resonance imaging (fMRI), a functional candidate gene association approach (of dopaminergic addictions-targeted polymorphisms), and the dopamine-modulating and…
- Trial name
- BAC (NCT01821560)
- Testing
- Baclofen
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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