Clinical trials: Consumption, Tobacco
Bipolar Disorder
Efficacy of N-Acetyl-Cysteine in Bipolar Disorder and Tobacco Use Disorder
Effects of N-Acetyl-Cysteine in patients with bipolar depression (primary outcome is Hamilton Depression Rating Scale) with and without tobacco use disorder and on inflammatory and oxidative stress biomarkers
- Trial name
- NACBD (NCT02252341)
- Testing
- N-Acetyl-Cysteine
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Universidade Estadual de Maringá
Tobacco Use Disorder, Nicotine Addiction
Cognitive Training for Nicotine Dependence
This randomized clinical trial tested the effects of a computerized (web-based) cognitive training intervention on smoking cessation.
- Trial name
- NCT01252966
- Testing
- Cognitive Training, Control training
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- University of Pennsylvania
Bladder Cancer, Breast Cancer
Physician-Initiated Stop-Smoking Program for Patients Receiving Treatment for Early-Stage Cancer
RATIONALE: Physician-initiated smoking cessation strategies may be effective in getting early-stage cancer patients to quit smoking.
- Conditions
- Bladder Cancer, Breast Cancer, Colorectal Cancer, Head and Neck Cancer
- Trial name
- NCT00002520
- Testing
- nicotine, Usual Care
- Where
- United States
- Volunteers
- 434 people
- Sponsor
- Eastern Cooperative Oncology Group
Tobacco Dependence
C-Raven, a Virtual Tobacco Cessation Intervention in the Community
In low-income housing units in Baltimore, the investigators propose to conduct a pilot two-arm hybrid type 1 effectiveness-implementation RCT comparing a) an avatar-delivered computerized intervention (CI) for tobacco cessation…
- Trial name
- NCT06545669
- Testing
- C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Smoking, Smoking Cessation
Addressing Parental Tobacco Use in Somali Immigrant Families: Adapting an Evidence-Based Intervention in Primary Care
This study will modify an existing evidence-based parental tobacco cessation intervention (the Clinical Effort Against Secondhand Smoke Exposure, or CEASE) delivered in pediatric primary care clinics to address shared tobacco use…
- Trial name
- NCT06839729
- Testing
- CEASE+
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use, Smoking
Salvation Army Tobacco Quit Line Referral Implementation Trial
The goal of this clinical trial is to understand how the Salvation Army staff can help people who use tobacco learn about and connect with no-cost treatments to help cut down or quit smoking.
- Conditions
- Tobacco Use, Smoking, Smoking Cessation
- Trial name
- NCT06689774
- Testing
- Cognitive-Motivational Feedback, Staff Tobacco Quit Line Referral Implementation Support, Consumer Incentives for Immediate Referral to a Tobacco Quit Line
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Wisconsin, Madison
Tobacco Use, HIV-1-infection
A Mobile Intervention to Promote Cessation in HIV-infected Smokers
The purpose of this study is to adapt an existing web-based tobacco treatment program for HIV-infected smokers into a mobile intervention delivered via smartphone.
- Trial name
- NCT02432482
- Testing
- mobile Positively Smoke Free (mPSF), Standard care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Montefiore Medical Center
Tobacco Dependence
Bioequivalence Between Two New Oral Nicotine Replacement Therapy Products and Nicorette® Microtab
The purpose of this study is to assess the bioequivalence between two new oral nicotine replacement therapy products and Nicorette® microtab.
- Trial name
- NCT01238640
- Testing
- Code STD, Code STE, Nicorette Microtab
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- McNeil AB
Smoking, Tobacco
Examining Brain Responses Linked to Emotion in Individuals Who Smoke Cigarettes
The study will use functional magnetic resonance imaging and facial coding methods to study individuals who smoke cigarettes. Smoking expectancy (the extent to which one perceives an opportunity to smoke a cigarette) will be…
- Trial name
- NCT04310735
- Testing
- Verbal smoking expectancy manipulation
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Penn State University
Tobacco Use
Testing Legally Feasible Options Studies 2/3
The overall aim of this research is to experimentally evaluate different, legally-viable approaches to reducing the impact of the point-of-sale (POS) retail environment on adolescent tobacco use risk.
- Trial name
- NCT05604508
- Testing
- Many posters with prices, Many posters, no prices, Fewer posters, no price restrictions
- Where
- United States
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- RAND
Nicotine Dependence, Nicotine Withdrawal
Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence
The objective of this proposal is to elucidate effects of bupropion SR + varenicline on smoking-cessation related processes in early abstinence using a human laboratory model.
- Trial name
- ChanBan (NCT00749658)
- Testing
- Bupropion, Varenicline
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use
Baby Albert: Electronic Cigarette Pharmacokinetics (PK) and Abuse Liability
The overall aim of the current research is to understand purchasing and product choice behaviors of tobacco/nicotine users if banning the sale of fully nicotinized cigarettes were to go into effect.
- Trial name
- NCT03637452
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Tobacco Dependence
Varenicline for Long-term Nicotine Replacement Therapy (NRT) Users
Primary aim: Will varenicline be better than placebo to get long-term users of NRT to stop? Secondary aim: To assess in details some side effects of varenicline i.e. nausea and abnormal dreams.
- Trial name
- NCT00977249
- Testing
- support and visits, varenicline
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Nicotine Use Disorder
Real Time fMRI and Quitting Smoking
This study will examine how real-time functional magnetic resonance imaging (rt-fMRI) feedback can be used to modulate brain activation in the context of smoking cues in order to resist craving.
- Trial name
- NCT03302026
- Testing
- Realtime biofeedback using fMRI
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Serious Mental Illness, Tobacco Use Disorder
Facilitation to Increase Tobacco Treatment
Smoking disproportionally impacts Veterans, and VA spends $2.7 billion annually on smoking-related health conditions. Veterans with serious mental illness (SMI) smoke tobacco products at triple the rate of Veterans without any…
- Trial name
- FITT (NCT07455526)
- Testing
- Multi-component facilitation
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- VA Office of Research and Development
Nicotine Dependence
Initial Screening of Gemfibrozil as a Novel Treatment for Tobacco Addiction
The purpose of this study is to investigate the effect of gemfibrozil on nicotine reinforcement and cue-elicited craving. Other objectives of this study include screening for the ability of gemfibrozil to aid smoking abstinence…
- Trial name
- NCT01876810
- Testing
- Gemfibrozil
- Where
- 2 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Smoking, Nicotine Dependence
Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace
This project will examine the impact of very low nicotine content (VLNC) cigarettes in a complex tobacco and nicotine product marketplace.
- Trial name
- NCT03272685
- Testing
- Very Low Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes
- Where
- 6 sites in United States
- Volunteers
- 799 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence
The Effect of Varenicline on D2/D3 Receptor Binding in Smokers
This study will evaluate effects of treatment with varenicline, a smoking cessation drug, on the dopaminergic system by using Positron Emission Tomography (PET) imaging with new radioligand, [11C]-(+)-PHNO.
- Trial name
- NCT01632189
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Centre for Addiction and Mental Health
Smoking Cessation, Nicotine Addiction
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from F8 coil or active rTMS from H coil for smoking cessation.
- Conditions
- Smoking Cessation, Nicotine Addiction, Schizophrenia
- Trial name
- NCT05276050
- Testing
- active F8-coil delivered rTMS, active H-coil delivered rTMS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston
Childhood Obesity, Smoking, Cigarette
Maternal Smoking Cessation and Pediatric Obesity Prevention
The objective of this study is to test the effect of smoking cessation in pregnancy or in lactation on preventing rapid infant adiposity gain.
- Conditions
- Childhood Obesity, Smoking, Cigarette, Pregnancy
- Trial name
- NCT03514602
- Testing
- Multicomponent behavioral intervention, Education only control
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
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