Clinical trials: Consumption, Tobacco
Smoking, Tobacco, Vaping
Investigating Exposure to Toxicants From Smoking and Vaping
Background: Many people who smoke use vaping products to help them quit. Levels of toxicants in urine samples are substantially lower in those who exclusively vape compared to those who smoke, suggesting that vaping poses only a…
- Conditions
- Smoking, Tobacco, Vaping, Mental Health Disorder
- Trial name
- NCT05953220
- Testing
- Exclusive tobacco smoking, Exclusive e-cigarette use, Dual use of e-cigarettes and tobacco smoking
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King's College London
Bladder Cancer, Cervical Cancer
Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking
RATIONALE: Stop-smoking plans, including counseling and nicotine replacement therapy, may help smokers quit smoking. It is not yet known whether counseling and the nicotine lozenge is more effective than counseling and the…
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00365508
- Testing
- nicotine lozenge, nicotine patch
- Where
- 10 sites in United States
- Volunteers
- 642 people
- Sponsor
- Fox Chase Cancer Center
Nicotine Dependence
Tobacco Use in Opioid Agonist Treated Pregnant Women
The primary objective of the proposed study is to evaluate the efficacy of tobacco abstinence-contingent voucher incentives versus non-tobacco abstinence-contingent incentives for reducing or eliminating tobacco use during…
- Trial name
- ROSE (NCT00497068)
- Testing
- tobacco abstinent contingent, non-contingent, control
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Johns Hopkins University
Smoking Cigarette, Smoking Behaviors
Vape Use Among Younger & Older Smokers
The study aims to recruit 100 current cigarette smokers (50 young adults ages 21-34; 50 older adults ages 35-65) who have tried vaping or are currently vaping (dual users).
- Conditions
- Smoking Cigarette, Smoking Behaviors, Vaping, Vaping Behaviors
- Trial name
- ENDS (NCT07214168)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Cannabis Dependence, Tobacco Use
Characterization of the Pattern of Consumption and Withdrawal Syndrome From Dual Cannabis and Tobacco Use
Aims: To characterize the pattern of cannabis and tobacco use and withdrawal symptoms in people who start treatment for cannabis use disorders (exclusive cannabis, concurrent and/or simultaneous with various tobacco products)…
- Conditions
- Cannabis Dependence, Tobacco Use, Withdrawal Syndrome, Substance Abuse
- Trial name
- DuCATA_GAMCaT (NCT05512091)
- Volunteers
- 282 people
- Sponsor
- Cristina Martínez Martínez
Tobacco Use Cessation
Targeting Mailed Nicotine Patch Distribution Interventions to Rural Regions of Canada
This study will examine the impact of mailed distribution of free Nicotine Replacement Therapy to smokers in rural regions. Telephone numbers will be randomly selected from across Canada in order to recruit adult smokers…
- Trial name
- NCT04606797
- Testing
- Nicotine patch
- Where
- Canada
- Volunteers
- 498 people
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Smoking, Vaping
Testing a School-Based E-cigarette, Tobacco, and Betel (Areca) Nut Use Prevention Curriculum for Guam Youths
The people of the U.S. Affiliated Pacific Islands (USAPI) face higher cancer incidence, especially lung/bronchia and head-and-neck cancer, and poorer cancer outcomes, compared with the U.S. nationally.
- Conditions
- Tobacco Smoking, Vaping, Tobacco Chewing
- Trial name
- NCT05037656
- Testing
- School-based curriculum
- Where
- Guam
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Guam
Nicotine Dependence, Major Depressive Disorder
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
Persons who struggle with depression smoke at high rates and experience low quit rates in treatment. The best way to improve cessation treatment for this underserved population remains unknown.
- Trial name
- NCT02378714
- Testing
- Varenicline, BASC, Standard treatment
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Smoking Cessation, Smoking
Testing the Efficacy of A Scalable, Telephone-Delivered, Guided Imagery Tobacco Cessation Intervention
The objective of this R01 application is to conduct a randomized controlled trial to test the efficacy of the Be Smoke Free, telephone-based, guided imagery (GI) intervention (IC) for smoking cessation compared to active…
- Conditions
- Smoking Cessation, Smoking, Smoking Reduction, Smoking, Cigarette
- Trial name
- NCT05277831
- Testing
- Guided Imagery Intervention, Standard Behavioral Control
- Where
- United States
- Volunteers
- 1,209 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Smoking Cessation, Tobacco Use
Mobile-based Peer Mentoring for Smoking Cessation
Despite the availability of a variety of effective treatments for smoking cessation, uptake of treatments is low. The increasing use of smartphone technology presents an exceptional opportunity to expand access to low-cost…
- Trial name
- NCT03048786
- Testing
- Control, Peer Mentoring
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use
Cross-Sectional Survey on the Use of Tobacco Products - London (UK)
The main purpose of the research study is to estimate the prevalence of tobacco product use and describe the tobacco use patterns in adults in London, United Kingdom.
- Trial name
- NCT03527030
- Testing
- Survey on Use of Tobacco Products in the General Population, Survey on Use of Tobacco Products in IQOS Users
- Where
- Switzerland
- Volunteers
- 6,116 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
E-cigarette Use, Cigarette Smoking
Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
This between-subjects study aims to evaluate whether e-cigarettes (ECIGS) versus oral nicotine pouches (ONPS) more readily substitute for combustible cigarettes among 200 cigarette smokers.
- Conditions
- E-cigarette Use, Cigarette Smoking, Harm Reduction, Tobacco Use
- Trial name
- NCT06372899
- Testing
- E-cigarettes, Oral nicotine pouches
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
HIV/AIDS, Smoking Cessation
Learn to Quit-HIV Pilot Study
The study team will conduct a feasibility, acceptability, and preliminary efficacy trial comparing Learn to Quit-HIV (n=30) to an app based on U.S.
- Conditions
- HIV/AIDS, Smoking Cessation, Tobacco Use Disorder
- Trial name
- NCT04609514
- Testing
- Learn to Quit-HIV, QuitGuide, Nicotine patch
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Duke University
Nicotine Addiction
tDCS Effects on Resisting Smoking: Dose Ranging Study
Behaviors such as tobacco use, unhealthy diet, and sedentary behavior have far-reaching health implications. These modifiable behaviors account for a substantial proportion of deaths from cancer, cardiovascular disease and…
- Trial name
- RDR (NCT02624284)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking, Nicotine Addiction
The END Perioperative Smoking Pilot Study
The purpose of this pilot randomized trial is to determine the feasibility of e-cigarettes and telephone counselling (compared to transdermal nicotine replacement and telephone counselling) as a harm-reduction tool that may lead…
- Conditions
- Smoking, Nicotine Addiction, Surgery
- Trial name
- NCT02482233
- Testing
- ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Healthy Smokers
Nicotine Patch - Multidose Bioequivalence Study
The purpose of this study is to compare the relative bioavailability of nicotine following repeated applications of a new transdermal formulation to that of a reference formulation. Up to day 7
- Trial name
- NCT01658215
- Testing
- V0116 transdermal patch (Test treatment ), Nicotine transdermal patch (Reference treatment )
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Medicament
Breast Cancer, Psychology, Social
Effectiveness of Screening and Brief Interventions for Alcohol and Tobacco During Breast Cancer Treatment (ONKODETOX)
Despite scientific, clinical and political incentives, alcohol and/or tobacco screening and brief intervention (SBI) services are poorly implemented in oncology settings.
- Trial name
- ONKODETOX (NCT03371732)
- Testing
- Motivational Intervention group, Educational advises group
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Institut Bergonié
Nicotine Vaping, Nicotine Dependence
Assess the Influence of Nicotine Flux and Nicotine Form on Subjective Effects Related to Dependency
Electronic nicotine delivery systems (ENDS) heat and vaporize a nicotine-containing liquid to produce an aerosol that can deliver nicotine to the blood and the brain.
- Conditions
- Nicotine Vaping, Nicotine Dependence, Nicotine Addiction
- Trial name
- NCT05430334
- Testing
- e-liquid 1, e-liquid 2, e-liquid 3
- Where
- Lebanon
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Cigarette Smoking, Tobacco Use
Electronic Cigarette Use in Young Adult Men and Women
This one-year pilot study of 30 non-treatment seeking young adult e-cigarette/combustible tobacco product dual users (15 males/15 females) will use smartphone-based ecological momentary assessment (EMA) to gather real-time data…
- Trial name
- NCT03089541
- Testing
- Survey Arm
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University
Tobacco Use Disorder
Naltrexone Augmentation of Nicotine Patch Therapy - 1
Naltrexone Augmentation of Nicotine Patch Therapy
- Trial name
- NCT00218153
- Testing
- Naltrexone
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
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