Clinical trials: Consumption, Tobacco
Tobacco Cessation
Adaptation and Evaluation of a Tobacco Cessation Program: An Integrated mHealth Approach
We developed and established the efficacy of a theory-based, culturally- and gender-relevant Community Health Worker (CHW) intervention for low-income Brazilian women that augments the tobacco cessation program offered through…
- Trial name
- NCT04865276
- Testing
- Integrated tobacco cessation intervention delivered by Community Health Workers with the support of an App (mHealth) + Tobacco cessation program at the public health system
- Where
- Brazil
- Volunteers
- 431 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cigarette Smoking, Nicotine Vaping
Promotion and Mitigation Factors Leading to Illegal Tobacco Purchases
This study will investigate the effects of promotion factors and mitigation strategies on legal and illegal tobacco purchases for different tobacco-user types.
- Trial name
- NCT06001840
- Testing
- Promotion factors, Mitigation strategies
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Virginia Polytechnic Institute and State University
THC, Cannabis
THC Crossover Study
This is a randomized, crossover study enrolling experienced dual cannabis-tobacco smokers (N=18) to describe the differences in THC and toxicant exposure, examining pharmacokinetic, subjective, and cardiovascular effects from…
- Conditions
- THC, Cannabis, Cannabis Smoking, Cannabis Use, Unspecified
- Trial name
- TRDRP (NCT04429568)
- Testing
- Smoked Cannabis, Vaped Cannabis, Tobacco Cigarette
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Substance Use Disorders
Technologically-Augmented Referrals to Mitigate Addiction Consequences
The implementation of screening and intervention for substance use disorders, such as Screening Brief Intervention Referral to Treatment (SBIRT), in the primary care setting has faced several challenges.
- Trial name
- TARMAC (NCT04401215)
- Testing
- Technology Augmented Treatment for Screening, Brief Intervention, Referral, and Treatment (SBIRT)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Washington State University
Social Anxiety Disorder, Tobacco Use Disorder
Adaptive Treatment Strategies for Improving Engagement With a Web-Based Smoking Intervention in Socially Anxious Smokers
This phase I trial will use a pilot sequential multiple assignment randomized trial (SMART) to examine protocol feasibility and acceptability of new components of a web-based intervention for socially anxious smokers.
- Trial name
- NCT04260776
- Testing
- Phase 1: Web-based intervention (MyWebQuit) with 1-way text messages, Phase 1: Web-based intervention (MyWebQuit) with interactive, 2-way text messages, Phase 2: re-engagement text messages
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cigarette Smoking
The Impact of Innovative Tax Proposals on Purchase Patterns
This study will investigate the effect of four tax proposals (i.e. Tobacco Parity, Nicotine-Content, Harm-Reduction, and Modified Risk Tobacco Product-related taxes) on tobacco product purchasing patterns.
- Trial name
- NCT05370313
- Testing
- Market Price Condition (control), Tobacco Parity Tax Condition, Nicotine-Content Tax Condition
- Where
- 2 sites in United States
- Volunteers
- 285 people
- Sponsor
- Virginia Polytechnic Institute and State University
Cigarette Smoking
Smoking Interventions for Hospital Patients
Cigarette smoking is the leading preventable cause of death in the U.S. Nearly 4 million U.S. smokers are hospitalized each year, many of them at high risk for tobacco-related disease or death.
- Trial name
- Helping HAND (NCT01177176)
- Testing
- Extended Care Management, Standard Care
- Where
- United States
- Volunteers
- 397 people
- Sponsor
- Massachusetts General Hospital
Acute Respiratory Distress Syndrome, Tobacco; Use, Rehabilitation
Rehabilitation Techniques on Survivors of Acute Respiratory Distress Syndrome
A randomized controlled blinded study in patients treated for Acute Respiratory Distress Syndrome (ARDS) in the mixed medical-surgical intensive care units (ICU) of four academic teaching hospitals in Tehran, Iran were conducted…
- Trial name
- NCT02787720
- Testing
- Family centered empowerment model, Continuous care model
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Baqiyatallah Medical Sciences University
Nicotine Dependence, Schizophrenia
Extended Duration Nicotine Replacement Therapy and Bupropion in Smokers With Schizophrenia
After successfully quitting smoking, smokers with schizophrenia are vulnerable to relapse shortly after discontinuation of treatment.
- Trial name
- NCT01576640
- Testing
- NRT, Bupropion SR 150mg bid, Relapse Prevention-Oriented Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Massachusetts General Hospital
Smoking
Medical Student INtervention to Promote Effective Nicotine Dependence and Tobacco HEalthcare
Background: Smoking counselling during hospitalisation with post-discharge follow-up increases quitting. However, provision of cessation care for hospitalised patients is suboptimal.
- Trial name
- MIND-THE-GAP (NCT02601599)
- Testing
- Motivational interviewing
- Where
- Ireland
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Copd, Smoking
Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease that affects only a fraction of those who smoke tobacco.
- Conditions
- Copd, Smoking, Tobacco Use
- Trial name
- Pre-COPD Pilot (NCT04722835)
- Testing
- Bronchoscopy with Bronchoalveolar Lavage (BAL)
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Nicotine Addiction
Effect of Galantamine on Smoking Abstinence
This is a preliminary open-label study to determine whether a medication called galantamine (Brand Name: Razadyne) will help smokers quit and whether it reduces cognitive problems that smokers experience during a quit attempt.
- Trial name
- NCT01548638
- Testing
- Galantamine ER
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pennsylvania
Attention Deficit Hyperactivity Disorder, Nicotine Dependence
Attention Deficit Hyperactivity Disorder (ADHD) Smoking Cessation Study
The overall goal of the present project is to investigate whether lisdexamphetamine (LDX; Vyvanse) is an effective adjunct to nicotine replacement therapy (NRT) to promote smoking cessation in patients with comorbid Attention…
- Trial name
- NCT00736255
- Testing
- Transdermal Nicotine Patch, Lis-dexamphetamine (Vyvanse)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Duke University
Tobacco Prevention, Environmental Tobacco Smoke Exposure
The Impact of a Tobacco Control Intervention in African-American Families
The purpose of this randomized control trial is to evaluate the effects of a multi-component intervention aimed at: 1. preventing tobacco initiation in youth 2. promoting anti-tobacco socialization in the home 3.
- Conditions
- Tobacco Prevention, Environmental Tobacco Smoke Exposure, Tobacco Cessation
- Trial name
- NCT01164306
- Testing
- LifeSkills Training, Healthy Lifestyle Behavior Choices, NRT and Motivational Interviewing (MI)
- Where
- United States
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- Augusta University
Cigarette Smoking
A Virtual Arm to Stop Smoking
The investigators reported in a pilot study presented at last year's Cybertherapy Conference (Girard \& Turcotte, 2007) that using an action-cue exposure strategy in virtual reality (ACE-VR; crushing virtual cigarettes) might be…
- Trial name
- NCT00639093
- Testing
- psychoeducational / motivational combined with crushing, psychoeducational / motivational combined with control
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Universite du Quebec en Outaouais
Second Hand Tobacco Smoke, Nicotine Dependence
Kids Safe and Smokefree (KiSS)
The study's primary aim is to test the hypothesis that an intervention integrating pediatric clinic-level quality improvement with home-level behavioral counseling (CQI+BC) will result in greater reductions in child cotinine (a…
- Trial name
- KiSS (NCT01745393)
- Testing
- Clinic Quality Improvement + Behavioral Counseling, Clinic Quality Improvement + Attention Control
- Where
- 4 sites in United States
- Volunteers
- 327 people
- Sponsor
- Temple University
Bladder Cancer, Cervical Cancer
Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking
RATIONALE: A stop-smoking plan that includes health education counseling and bupropion may help African-American smokers stop smoking.
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00666978
- Testing
- smoking cessation intervention, bupropion hydrochloride, gene expression analysis
- Where
- 2 sites in United States
- Volunteers
- 540 people
- Sponsor
- Lisa Sanderson Cox, PhD
Obesity, Overweight
Semaglutide for Post-Smoking Cessation Weight Management
This trial will examine the effect of semaglutide 2.4mg on changes in body weight, body composition, and peripheral and central mechanisms that control appetite, satiety, and food intake in the context of smoking cessation.
- Conditions
- Obesity, Overweight, Cigarette Smoking
- Trial name
- NCT06173778
- Testing
- semaglutide 2.4mg, Nicotine Replacement Therapy (NRT, nicotine patch), Brief Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Tobacco Use
Telephone and Web-based Teen Tobacco Cessation in HMOs
The purpose of this study is to look at both the clinicians' ability to reach out to the teen smokers and to evaluate the efficacy of providing tobacco cessation support using a proactive telephone quitline combined with an…
- Trial name
- QWIThelper (NCT00311948)
- Testing
- Telephone counseling + interactive website = more abstinence, Behavioral: interactive website
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Kaiser Permanente
Nicotine Dependence
Trial on the Effectiveness of Mindfulness Training for Smokers
The Mindfulness Training for Smokers study follows a randomized controlled design with 240 total participants. Both the study group and the control group will be enrolled in the Wisconsin Tobacco Quit Line and will receive four…
- Trial name
- MTS (NCT01093599)
- Testing
- Quit Line plus MTS, Quit Line Only
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- University of Wisconsin, Madison
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