Clinical trials: Consumption, Tobacco
Cigarette Smoking
Strengthening Instrumental Extinction to Prevent Smoking Relapse (VLNCCue)
The central objective of the project is to evaluate the effect of incorporating smoking related contexts into very low nicotine content (VLNC) cigarette extinction trials on clinically relevant, smoking-related outcomes.
- Trial name
- VLNCCue (NCT02538042)
- Testing
- Nicotine Patch, SPECTRUM Nicotine Research Cigarettes (0.07 mg), MCE+
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Francis McClernon, Ph.D.
Nicotine Dependence
Prize Reinforcement for Smoking Cessation
Nicotine dependence is prevalent in society, cigarette smoking is associated with several known health risks, and most dependent individuals find it very difficult to stop smoking cigarettes.
- Trial name
- NCT00865254
- Testing
- Standard Treatment, Traditional Contingency Management, Early Enhanced Contingency Management
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Smoking, Nicotine Dependence
Short Term Effects of Electronic Cigarettes in Tobacco Dependent Adults
This is a pilot human experimental study to evaluate whether the use of an e-cigarette affects lung function, exhaled CO levels, and quantitative tobacco cigarette consumption in active tobacco smokers.
- Trial name
- NCT02498145
- Testing
- Nicotine e-cigarette, Non-nicotine e-cigarette
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yale University
Nicotine Use Disorder
Pharmacokinetics and Acute Effects of Multiple Dose of Nicotine: Electronic Cigarette and Cigarette
The purposes of this study are 1) to determine the pharmacokinetics of nicotine after multiple dose administration by electronic cigarette and 2) to compare the acute effects of multiple dose of nicotine administrated by…
- Trial name
- NCT02511704
- Testing
- Nicotine
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Nicotine Addiction, E-Cig Use
Quit Smoking Study for People Who Use E-Cigarettes
The overarching aim of this proposed randomized controlled trial (RCT) is to test nicotine replacement therapy (NRT) with text message support for two smoking cessation approaches among young adult dual users of combustible…
- Conditions
- Nicotine Addiction, E-Cig Use, Quitting Smoking
- Trial name
- NCT04946825
- Testing
- Nicotine replacement therapy patch, Nicotine replacement therapy lozenge, Quit electronic cigarettes
- Where
- United States
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Healthy, Cigarette Smoking
A Study of Inhalation of 20,000 EU CCRE and Mucociliary Clearance (MCC) in Otherwise Healthy Individuals Who Are Current Cigarette Smokers
The purpose of this Phase 1 research study is to identify a dose of inhaled endotoxin that is safe (does not cause prolonged cough, shortness of breath or other problems), but causes changes in sputum cell samples that the…
- Trial name
- IRB 09-0259 (NCT00924768)
- Testing
- 20K EU CCRE
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Smoking, Smoking Cessation
Evaluation of National Cancer Institute Young Adult Stop-Smoking Program
Background: Researchers want to see how well the QuitTXT text-message program helps smokers ages 18 29 stop smoking. This is part of a larger online stop-smoking program by the National Cancer Institute.
- Conditions
- Smoking, Smoking Cessation, Cigarette Smoking, Tobacco, Smoking
- Trial name
- NCT01885052
- Testing
- QuitTXT Study, Low Contact
- Where
- United States
- Volunteers
- 4,432 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Smoking Cessation, Nicotine Addiction
Nicotine Receptor Levels and Smoking Cessation
The investigators propose to use positron emission tomography (PET) imaging to determine whether nicotinic receptor availability at pretreatment predicts smoking cessation success.
- Trial name
- NCT01788943
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Lung Carcinoma, Tobacco Use Disorder
Intermittent or Continuous Acetylsalicylic Acid and Gene Expression in the Nasal Tissue of Current Smokers
This randomized phase II trial studies the safety and effects of acetylsalicylic acid (aspirin) taken continuously or intermittently on gene expression in the nasal tissue of current smokers.
- Trial name
- NCT02123849
- Testing
- Aspirin, Laboratory Biomarker Analysis
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Tobacco Use, Smoking Cessation
Chatbot Counselling for Smoking Cessation in Youths
The goal of this pilot trial is to develop and examine the trial feasibility and acceptability of a chatbot for smoking cessation in youth smokers. Specific aims include: 1.
- Trial name
- NCT06470776
- Testing
- Chatbot counselling, Peer counselling
- Where
- Hong Kong
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking Reduction, Tobacco Use
Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment
This pragmatic trial will evaluate the value of routinely providing proactive smoking cessation support to current smokers as a part of participating in lung cancer screening within Veterans Health Administration.
- Conditions
- Smoking Reduction, Tobacco Use, Tobacco Smoking, Tomography
- Trial name
- PROACT (NCT03612804)
- Testing
- Unsigned note to provider about cessation medication prescription, Proactive Telephone Counseling from VA Quitline
- Where
- 3 sites in United States
- Volunteers
- 944 people
- Sponsor
- VA Office of Research and Development
Tobacco Use Cessation, Second Hand Tobacco Smoke
Community-Partnered Dominican Republic Tobacco Control
Tobacco use and tobacco-caused illnesses and death are increasing in developing countries globally, so it is critical to study these countries in order to effectively address the tobacco epidemic.
- Trial name
- NCT01228916
- Testing
- Tobacco Cessation and Secondhand Smoke Reduction
- Where
- Dominican Republic
- Volunteers
- 3,273 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Tobacco Cessation
Medium Vs Low Intensity Intervention in Tobacco Cessation and Control in Zari Workers
Zari workers in Mumbai city will be assessed for tobacco consumption habit. They will be divided into 3 arms as - 1) First arm will get Medium intensity tobacco cessation intervention 2) Second arm will get low intensity tobacco…
- Trial name
- ZARI (NCT02103868)
- Testing
- Tobacco Cessation Counseling
- Where
- India
- Volunteers
- 400 people
- Sponsor
- Tata Memorial Hospital
Alcohol Consumption, Tobacco Use
Interactive Psychopharmacologic Effects of Alcohol and Nicotine in Humans
The purpose of this study is to characterize the interactive effects of acute intravenous (IV) alcohol and nicotine administration in male and female smokers and nonsmokers who use alcohol.
- Trial name
- NCT00616746
- Testing
- Nicotine, Ethanol
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Yale University
Tobacco Use Disorder
Computer-Based Stop Smoking Program in Assisting Doctors in Helping Adults Stop Smoking
RATIONALE: Computer-based stop smoking programs may assist doctors in helping patients stop smoking. PURPOSE: This randomized clinical trial is studying how well a computer-based stop smoking program works in assisting doctors in…
- Trial name
- NCT00383461
- Testing
- smoking cessation intervention, counseling intervention
- Where
- 2 sites in United States
- Volunteers
- 4,314 people
- Sponsor
- Brigham and Women's Hospital
Nicotine Addiction
Nicotinic Receptor Levels After Stopping Smoking
This positron emission tomography (PET) study examines the effects of 24 hours abstinence from smoking on return to availability of neuronal nicotinic receptors in slow and fast metabolizers of nicotine.
- Trial name
- NCT01704573
- Testing
- 2-[18F]-fluro-3-[2(S)-2-azethidinylmethoxy]-pyridine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Environmental Tobacco Smoke Exposure, Depression
Healthy Outcomes of Pregnancy Education
The purpose of this study is to determine if an integrated intervention addressing active smoking, environmental tobacco smoke exposure, depression and intimate partner violence, would improve pregnancy outcome among African…
- Conditions
- Environmental Tobacco Smoke Exposure, Depression, Partner Abuse, Tobacco Smoking
- Trial name
- NCT00381823
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 1,750 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Tabacco Use Disorder, rTMS
Personalized Brain Stimulation to Help Veterans Quit Smoking
Cigarette smoking is a significant public health concern for Veterans. Encouraging smoking cessation continues to be a top priority for the Veterans' Administration as Veterans who use tobacco experience negative health effects…
- Trial name
- VICTOR (NCT07050862)
- Testing
- Transcranial Magnetic Stimulation, Personalized-image-guided and E-field-modeling dose rTMS (precision TMS)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- VA Office of Research and Development
Tobacco Smoking
Smoking Prevalence at a University Hospital
Tobacco is the leading risk factor for avoidable mortality in France and around the world. It is also the second cause of life with disability in the world and the leading preventable risk factor for cancer in France and…
- Trial name
- TABAC-HCL (NCT03268980)
- Testing
- Questionnaire Hospital Staff group, Questionnaire students and patients group
- Where
- France
- Volunteers
- 11,276 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
E-cigarette Use, Tobacco Use Cessation
Attentional Bias Modification Training for E-cigarette Users
Aims are to (1) evaluate attentional bias to e-cigarette cues between the intervention and control groups at post-intervention as compared to the pre-intervention; and (2) test the feasibility and efficacy of the intervention at…
- Trial name
- NCT05112562
- Testing
- Computerized attentional bias modification training
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Milwaukee
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