Clinical trials: Contact Dermatitis
Diaper Rash
Clinical Study to Evaluate the Efficacy and Safety of Two Marketed Investigational Products in Children With Diaper Rash
To evaluate whether Desitin; Zinc Oxide Diaper Rash Ointment (Desitin Original) and Desitin Creamy; Zinc Oxide Diaper Rash Ointment (Desitin Creamy) provide relief of the signs and symptoms associated with diaper rash after 12…
- Trial name
- NCT00219466
- Testing
- Zinc Oxide Diaper Rash Ointment, Aloe Vera/Tocopherol/Zinc Oxide Cream
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Ultraviolet Rays, Immunosuppression
Effect of RANKL Inhibition on UV-induced Immunosuppression
Ultraviolet (UV) light is part of normal sunlight and has many effects on human skin and health. One of the harmful effects of long-term UV light exposure is that it can cause skin cancer.
- Conditions
- Ultraviolet Rays, Immunosuppression, Hypersensitivity, Delayed, Immune Tolerance/Drug Effects
- Trial name
- NCT01978483
- Testing
- Denosumab, UVB exposure, Diphenylcyclopropenone
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Psoriasis, Atopic Dermatitis
Novel Skin Barrier Product Versus Petrolatum for Skin Barrier Dysfunction
The goal of this clinical trial is to learn if a novel barrier topical product works to treat barrier dysfunction in adults. It will also learn about the safety of the novel barrier topical product.
- Conditions
- Psoriasis, Atopic Dermatitis, Xerosis, Contact Dermatitis
- Trial name
- NCT07183423
- Testing
- Novel barrier repair topical product, Petrolatum
- Where
- Philippines
- Volunteers
- 26 people
- Sponsor
- Makati Medical Center
Surgical Incision
Silk Scaffold Surgical Incision Dressing
Interventional Study of the novel clinical application of SERI surgical silk scaffold affixed with dermaFLEX medical adhesive as a wound dressing, compared to two separate current standard of care for surgical incision closure…
- Trial name
- SSSID (NCT05508945)
- Testing
- Dermabond Prineo Skin Closure System, silk, 3M Steri-Strip
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Mehrdad Mark Mofid
Irritant Contact Dermatitis Due to Incontinence, Diaper Rash
Comparison of Wash Wipes and Standard Care in the Prevention of Incontinence-associated Dermatitis in Elderly
Incontinence is a widespread problem in all health care setting. One of the main complications of incontinence is inflammation of the skin in the genital and anal region, also known as incontinence-associated dermatitis (IAD).
- Conditions
- Irritant Contact Dermatitis Due to Incontinence, Diaper Rash, Pressure Ulcer, Incontinence-associated Dermatitis
- Trial name
- NCT02475512
- Testing
- Wash wipes (3M), water and pH neutral soap
- Where
- 11 sites in Belgium
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- University Ghent
Contact Dermatitis
DermAI to Evaluate Human Factor of Testing
The purpose of this research is to improve how well remote patch allergy testing works and make sure they are easy and practical for people to use from home.
- Trial name
- NCT06387472
- Testing
- AI algorithm to evaluate photographs of skin test patch regions, Allergen Patch
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Psoriasis, Contact Dermatitis of Hand
An Open-label Controlled Trial: Effectiveness of Balneotherapy in Palmoplantar Psoriasis and Contact Dermatitis.
Patients who had an indication for phototherapy were included in this study. The treatment was used as a monotherapy protocol. The standard protocol for bathing PUVA involved applying 0.01% bath psoralen for 15 minutes, while the…
- Trial name
- NCT06458868
- Testing
- salt water or tap water before UVA
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ankara University
Stevens-Johnson Syndrome, Graft Versus Host Disease in Eye
Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease
The goal of this research is to determine if the Tangible Boost system adequately replenishes the Hydra-PEG coating on the surface of a rigid contact lens.
- Conditions
- Stevens-Johnson Syndrome, Graft Versus Host Disease in Eye, Sjogren's Syndrome, Dry Eye
- Trial name
- NCT04313725
- Testing
- Tangible Boost
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Tangible Science
Skin Cancer
An Immunonutritional Approach to the Prevention of Skin Cancer
Skin cancer incidence continues to rise and ultraviolet radiation (UVR) in sunlight is the principal cause. Solar UVR can promote cancer development through its ability to suppress the immune system.
- Trial name
- NCT01032343
- Testing
- Omega-3 PUFA, Gelatine
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Diaper Dermatitis, Urinary Tract Infections
Intervention to Reduce Diaper Need and Increase Use of Pediatric Preventive Care
Well-child care is the primary source of preventative health care for children. These visits provide an opportunity for physicians to assess an infant's biomedical health, development, and behavior, as well as help ensure timely…
- Conditions
- Diaper Dermatitis, Urinary Tract Infections, Infection, Depressive Symptoms
- Trial name
- NCT03490045
- Testing
- Diaper Incentive, Conditional Cash Transfer Condition
- Where
- 2 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Yale University
Sensitivity, Contact, Photosensitivity
Dermatological Assessment of Primary Dermal Irritability Accumulated, Sensitization, Photoallergy and Photosensitization of a Scar Gel
Evaluate the potential of Primary Dermal Irritability, Accumulated Dermal Irritability, Dermal Sensitization, Photoallergy and Photosensitization, of health products through the application of Patch Test, proving the safety of…
- Conditions
- Sensitivity, Contact, Photosensitivity, Phototoxicity
- Trial name
- NCT06723340
- Testing
- Scar gel
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Acceptance, Social, Sensitivity, Contact
Evaluation of Cutaneous Acceptability and Perceived Effectiveness of a Nasal Spray (Health Care Products)
This is a clinical study for health care product safety assessment. The research is going to conducted with 45 subjects, aged 18 to 70 years, women users of the product category, regardless of color/race, ethnicity, sexual…
- Trial name
- NCT05508230
- Testing
- Hyaluronic Nasal Spray
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Eczema, Allergic Contact Eczema Nos
Molecular Diagnosis of Allergic Contact Dermatitis (SMECA).
Allergic contact dermatitis (ACD) is a common inflammatory skin disease, which represents a major public health issue in industrialized countries.
- Trial name
- SMECA (NCT06124781)
- Testing
- Blood sample, Skin biopsies, ROAT test
- Where
- 5 sites in Belgium, France
- Volunteers
- 60 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Diaper Rash
Infant Microbiome in Diaper Rash
The objective of this study is to evaluate the microbiome composition of infant's (9-12 month) skin experiencing diaper rash in order to determine if the onset and severity of erythema associated with diaper rash is influenced by…
- Trial name
- NCT02893501
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Kimberly-Clark Corporation
Diaper Rash
CeraVe Cream Compared to Desitin Paste for Treating Diaper Dermatitis in Infants
This is a single-center, 1:1 randomized, double-blind, parallel-group, non-inferiority controlled trial to demonstrate non-inferiority of CeraVe Baby Diaper Rash Cream compared to Desitin Maximum Strength Original Paste when…
- Trial name
- NCT02299206
- Testing
- CeraVe Baby Diaper Rash Cream, Desitin Maximum Strength Original Paste
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Northwestern University
High-grade Dysplasia in Barrett Esophagus, Non Small Cell Lung Cancer
Efficacy and Safety of a Sunscreen Against Porfimer Sodium-induced Phototoxicity to Visible Light
Photodynamic therapy (PDT) uses a combination of a drug, porfimer sodium, and a light from a non heated laser. The activation of the drug is done by illuminating abnormal areas using a fiber optic device.
- Conditions
- High-grade Dysplasia in Barrett Esophagus, Non Small Cell Lung Cancer, Esophageal Cancer
- Trial name
- NCT01256203
- Testing
- Solar Protection Formula SPF® 60, Photobiological testing
- Sponsor
- Pinnacle Biologics Inc.
Diaper Rash
Determination of Safety and Consumers' Satisfaction of Moussik Versus Desitin Creamy Ointment in Diaper Rash Prophylaxis
The purpose of this clinical observation is to evaluate the safety and consumers' satisfaction of Moussik vs Desitin Creamy ointment as a diaper rash protection product.
- Trial name
- NCT01167465
- Testing
- Moussik Diaper Rash Mousse, Desitin Creamy Ointment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Trima, Israel Pharmaceutical Products
Dermatitis, Contact, Dermatitis
Post-Marketing Clinical Follow-Up Trial to Evaluate the Performance and Safety of the Medical Device 047 TD Dermatitis Cream in Adults and Children With Atopic and Contact Dermatitis Symptoms Confirmed by Clinical Parameters
The study aims to evaluate and confirm the performance of 047 TD Dermatitis cream in the improvement of eczematous dermatitis and contact dermatitis, throughout a reduction in disease severity and symptoms.
- Conditions
- Dermatitis, Contact, Dermatitis, Dermatitis, Chronic, Dermatitis, Eczematous
- Trial name
- NCT07056569
- Testing
- 047_TD Dermatitis cream twice a day for 28 days
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Biokosmes Srl
Diaper Rash
Effects of Argan Spinosa Oil in the Treatment of Diaper Dermatitis in Infants and Toddlers
The study hypothesized that using the traditional medicinal product of Argan spinosa oil is more effective than conventional topical steroid ointment on the speed up of the healing process and alleviation the symptoms in children…
- Trial name
- NCT04210674
- Testing
- The traditional medicinal product of Argan spinosa oil
- Where
- 3 sites in Jordan
- Volunteers
- 150 people
- Sponsor
- Jordan University of Science and Technology
Irritant Dermatitis, Stoma Site Dermatitis
Effectiveness of 3M Cavilon Advanced Skin Protectant in the Treatment of Moisture-associated Skin Damage in Hospitals
Objectives: The aim of this study is to evaluate the effectiveness of 3M™ Cavilon™ Advanced Skin Protectant in the treatment of partial-thickness wounds caused by moisture (MASD) compared to usual wound care treatment.
- Conditions
- Irritant Dermatitis, Stoma Site Dermatitis, Wound of Skin
- Trial name
- ISR-CASP-MASD (NCT06178289)
- Testing
- 3M Cavilon Advanced Skin Protectant, Standard hospital wound treatment protocol
- Where
- 3 sites in Belgium
- Volunteers
- 36 people
- Sponsor
- University Ghent