Clinical trials: Contact Lens Dry Eye
Dry Eye
Optimization of Assessment and Grading for Lid Wiper Epitheliopathy
The purpose of this study is to assess eyelid margin staining, termed "lid wiper epitheliopathy" (LWE), in three populations. The hypothesis is LWE will be more prevalent in symptomatic contact lens wearers than non-symptomatic…
- Trial name
- BURNABY (NCT01611922)
- Testing
- Ophthalmic dye, Contact lenses
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Dry Eye
A Four Week Study of Azithromycin Ophthalmic Solution, 1% Versus Rewetting Drops in Subjects With History and Current Complaint of Contact Lens-Related Dry Eye (CLDE)
The primary objective of this study is to compare the duration of subject reported comfortable contact lens daily wear time in subjects with a history and current complaint of CLDE during a 29-day treatment period of azithromycin…
- Trial name
- NCT01105624
- Testing
- azithromycin ophthalmic solution, 1%, Visine® for Contacts®
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Merck Sharp & Dohme LLC
Dry Eye
A 2-week Clinical Comparison of SYSTANE® Ultra to Sensitive Eyes Rewetting Drops in Contact Lens Wearing Patients.
To evaluate safety with the use of Systane Ultra in contact lens wearers. A comparison to a currently marketed contact lens rewetting drop will be included as a control.
- Trial name
- NCT00769665
- Testing
- Systane Ultra, Sensitive Eyes Rewetting Drops
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Myopia, Dry Eye
Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber
The purpose of this study is to evaluate two different types of contact lenses and their effect on dry eyes when compared to wearing glasses in a controlled, low humidity chamber.
- Trial name
- NCT01482312
- Testing
- lotrafilcon A contact lenses, comfilcon A contact lenses, Glasses
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- CIBA VISION
Dry Eye Syndrome, Myopia
Clinical Evaluation of a Daily Disposable Contact Lens in Symptomatic Weekly/Monthly Lens Wearers
The purpose of this study was to evaluate the reduction of contact lens-related dryness symptoms when symptomatic weekly/monthly contact lens wearers were switched to DAILIES® AquaComfort Plus® lenses for a two-week period using…
- Trial name
- NCT01614600
- Testing
- Nelfilcon A contact lenses
- Volunteers
- 88 people
- Sponsor
- Alcon Research
Stevens-Johnson Syndrome, Graft Versus Host Disease in Eye
Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease
The goal of this research is to determine if the Tangible Boost system adequately replenishes the Hydra-PEG coating on the surface of a rigid contact lens.
- Conditions
- Stevens-Johnson Syndrome, Graft Versus Host Disease in Eye, Sjogren's Syndrome, Dry Eye
- Trial name
- NCT04313725
- Testing
- Tangible Boost
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Tangible Science
Dry Eye
Evaluation of Comfort of Ocular Lubricants in Symptomatic Contact Lens Wearers
The purpose of this study is to evaluate the ocular comfort of 3 ocular lubricants and a comparator.
- Trial name
- NCT05741216
- Testing
- OTF Ocular Lubricant, Ocular Lubricant
- Where
- 3 sites in Australia, Canada
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Dry Eye
A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear
Assess the impact of concomitant Miebo use while wearing contact lenses
- Trial name
- NCT07054606
- Testing
- Perfluorohexyloctane ophthalmic solution
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye, Dry Eye Syndromes
Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye
Tangible Hydra-PEG is a novel coating technology designed to improve lens wettability, deposit resistance, and tear film breakup time.
- Trial name
- NCT03417505
- Testing
- Scleral lenses treated with Tangible Hydra-PEG, Untreated scleral lenses
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Tangible Science
Dry Eye
Study to Evaluate a Contact Lens Lubricating and Rewetting Drop
The objective of this study is to evaluate the product performance of investigational lubricating and rewetting drops.
- Trial name
- NCT01267656
- Testing
- Lubricating and Rewetting Drops, AMO Blink Contacts Lubricant Eye Drops
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Eye Dryness
Clinical Trial for the Evaluation of Safety and Efficacy of Drop 0.4%
The aim of the trial is to compare the safety and efficacy of the moisturizing solution DROP 0.4% with the moisturizing solution AVIZOR EYE DROPS 0.2% PRESERVED in relieving the symptoms of dry eye over one month of use.
- Trial name
- DROP04 (NCT06985875)
- Testing
- Multidose mosturizing solution DROP 0.4%, Multidose mosturizing solution Avizor Eye Drops 0.2% Preserved
- Volunteers
- 79 people
- Sponsor
- Avizor SA
Myopia
A Prospective Study of Two Daily Disposable Contact Lenses
The purpose of this study was to evaluate the performance of a novel silicone hydrogel contact lens, DAILIES TOTAL1® (DT1) compared to the standard hydrogel material in 1-DAY ACUVUE® MOIST® (1DAVM) contact lens in contact lens…
- Trial name
- NCT01636986
- Testing
- Delefilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Dry Eye
Clinical Evaluation of a Multidose Preservative-free Lubricating Eye Drops Contained in Novelia® Eye Dropper in Non-Contact Lens Wearing Patients
This is a 30-Day, multi-site, single-masked, bilateral, active- controlled, 2-Arm parallel group study to evaluate the safety and efficacy of an Investigational product.
- Trial name
- NCT05661851
- Testing
- Investigational Lubricating Eye Drop in a Novelia® bottle, Blink® Tears eye Drops
- Where
- 8 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
OPTI-FREE® PureMoist® for Presbyopic Contact Lens Wearers
The purpose of this study is to evaluate OPTI-FREE® PureMoist® (OFPM) compared to non-HYDRAGLYDE® multi-purpose contact lens solutions in presbyopes currently wearing soft contact lenses and experiencing symptoms of dryness.
- Trial name
- NCT02965820
- Testing
- Opti-Free® PureMoist® contact lens solution, Habitual Multi-Purpose Contact Lens Solution, Habitual Contact Lenses
- Volunteers
- 122 people
- Sponsor
- Alcon, a Novartis Company
Dry Eye
Safety and Efficacy of Optive in Contact Lens Wearers With Dry Eyes
The purpose of this study is to determine if Optive®eye drops are safe for people who wear contact lenses and have dry eyes. The second goal of the study is to determine if using Optive®eye drops can improve my dry eye scores on…
- Trial name
- NCT00469573
- Testing
- 1. Optive
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Presbyopia
CLEAR CARE® PLUS for Presbyopic Contact Lens Wearers
The purpose of this study is to evaluate CLEAR CARE® PLUS (CCP) compared to non-HYDRAGLYDE® multi-purpose contact lens solutions in presbyopes currently wearing soft contact lenses and experiencing symptoms of dryness.
- Trial name
- NCT02965833
- Testing
- 3% hydrogen peroxide solution with HydraGlyde® Moisture Matrix, Habitual Multi-Purpose Contact Lens Solution, Habitual Contact Lenses
- Volunteers
- 126 people
- Sponsor
- Alcon, a Novartis Company
Dry Eye
Tear Evaluation Between Habitual Contact Lens Wearers and Non Contact Lens Wearers
to evaluate tears between habitual contact lens wearers and non contact lens wearers
- Trial name
- NCT01317030
- Testing
- Contact Lens Wear, Non-Contact Lens Wear
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye and Contact Lens Wear
Evaluation of Corneal Epithelial Thickness Mapping
Optovue has developed a new feature for mapping corneal epithelial thickness. The purpose of the study is to evaluate the accuracy and repeatability of the epithelial thickness measurement.
- Trial name
- NCT01712022
- Where
- 3 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Optovue
Contact Lens Wear
An Evaluation of a Marketed Lubricated Eye Drop in Soft Contact Lens Wearers Who Experience Ocular Dryness
Study to evaluate subjective comfort associated with the use of a marketed lubricant eye drop, by subjects reporting ocular dryness and wearing soft contact lenses on a daily disposable replacement schedule.
- Trial name
- NCT01132287
- Testing
- FID 112903
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Dry Eye, Contact Lens Acute Red Eye
Performance and Tolerability of the Medical Device LACRIACT
The goal of this study is testing LACRIACT® eye drops, a medical device, to see how well it works and if people can use it safely.
- Conditions
- Dry Eye, Contact Lens Acute Red Eye, Photophobia, Discomfort
- Trial name
- NCT06159569
- Testing
- LACRIACT
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Laboratórios Baldacci S.A