Clinical trials: Contact Lens Dry Eye
Contact Lens Complication, Astigmatism
Total30 for Astigmatism Contact Lenses
Determine if Total30 for Astigmatism contact lenses (CLs) provide a comfortable wearing experience all day. CL discomfort affects most CL wearers with discomfort consistently topping the reasons why established CL wearers drop…
- Conditions
- Contact Lens Complication, Astigmatism, Refractive Errors
- Trial name
- NCT06052046
- Testing
- TOTAL30 for Astigmatism Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Dry Eye
Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses
This research study is to see if using Lacrifill is safe, easy to use, and helpful for people who wear contact lenses but can't wear them comfortably for long.
- Trial name
- NCT07510620
- Testing
- Lacrifill
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists
Contact Lens Dry Eye
Use of 5.0% Lifitegrast Ophthalmic Solution for the Treatment of Dry Eye Disease in Contact Lens Wearers
Discomfort with contact lens wear is the biggest reason why people stop wearing contact lenses. The investigators believe that inflammation is one of the causes of discomfort, and by blocking the inflammation using lifitegrast…
- Trial name
- NCT03431272
- Testing
- Lifitegrast
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Contact Lens Discomfort, Dry Eye Disease
Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers
The purpose of this prospective study is to evaluate the benefits of using the Bruder Moist Heat Compress in contact lens wearers who report reduced comfortable wear time.
- Conditions
- Contact Lens Discomfort, Dry Eye Disease, Meibomian Gland Dysfunction
- Trial name
- NCT02848222
- Testing
- Bruder Moist Heat Compress, Washcloth
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Contact Lens Wearers With Dry Eye Syndrome
Efficacy of Cyclosporine Ophthalmic Emulsion in the Treatment of Dry Eye Syndrome in Contact Lens Wearers
Cyclosporine Ophthalmic Emulsion is currently used in the treatment of dry eye syndrome. Contact lens wearers frequently suffer from dry eye syndrome.
- Trial name
- NCT00335114
- Testing
- cyclosporine ophthalmic emulsion
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Dry Eye, Dry Eye Syndromes
Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye
Tangible Hydra-PEG is a novel coating technology designed to improve lens wettability, deposit resistance, and tear film breakup time.
- Trial name
- NCT03417505
- Testing
- Scleral lenses treated with Tangible Hydra-PEG, Untreated scleral lenses
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Tangible Science
Presbyopia
OPTI-FREE® PureMoist® for Presbyopic Contact Lens Wearers
The purpose of this study is to evaluate OPTI-FREE® PureMoist® (OFPM) compared to non-HYDRAGLYDE® multi-purpose contact lens solutions in presbyopes currently wearing soft contact lenses and experiencing symptoms of dryness.
- Trial name
- NCT02965820
- Testing
- Opti-Free® PureMoist® contact lens solution, Habitual Multi-Purpose Contact Lens Solution, Habitual Contact Lenses
- Volunteers
- 122 people
- Sponsor
- Alcon, a Novartis Company
Contact Lens Wear
An Evaluation of a Marketed Lubricated Eye Drop in Soft Contact Lens Wearers Who Experience Ocular Dryness
Study to evaluate subjective comfort associated with the use of a marketed lubricant eye drop, by subjects reporting ocular dryness and wearing soft contact lenses on a daily disposable replacement schedule.
- Trial name
- NCT01132287
- Testing
- FID 112903
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Dry Eye, Meibomian Gland Dysfunction
Crosslinked Hyaluronic Acid With Liposomes and Crocin in Dry Eye
A total of 50 eyes were analyzed (25 patients). The subjects selected were over 18 years of age. No gender distinction was made in the choice of subjects. All subjects were carriers of silicone hydrogel contact lenses.
- Conditions
- Dry Eye, Meibomian Gland Dysfunction, Dry Eye Syndromes
- Trial name
- NCT03617315
- Testing
- Hylauronic Acid
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Seville
Dry Eye
Study to Evaluate a Contact Lens Lubricating and Rewetting Drop
The objective of this study is to evaluate the product performance of investigational lubricating and rewetting drops.
- Trial name
- NCT01267656
- Testing
- Lubricating and Rewetting Drops, AMO Blink Contacts Lubricant Eye Drops
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye, Contact Lens Complication
Effects of Supplementation With PUFAs and Antioxidants for Contact Lens Discomfort
HydroEye® is a dietary omega 3 fatty acid supplement that contains both EPA and DHA, as well as GLA and ALA in the form of black currant seed oil.
- Trial name
- NCT04163328
- Testing
- HydroEye®
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Alabama at Birmingham
Cataract, Dry Eye
Efficacy of an Ocular Bandage Contact Lens for the Treatment of Dry Eye After Cataract Surgery
To study the efficacy of an ocular bandage contact lens for the treatment of dry eye after cataract surgery
- Trial name
- NCT04100031
- Testing
- bandage contact lenses, phacoemulsification
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Contact Lens Complication, Astigmatism
T30 for Astigmatism in Digital Device Users
This study aims to determine if Total30 lenses for astigmatism can be successfully fit in participants who are heavy digital device users.
- Conditions
- Contact Lens Complication, Astigmatism, Refractive Errors
- Trial name
- T30FA (NCT06266728)
- Testing
- Total30 for Astigmatism Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Dry Eye, Contact Lens Complication
Total30 For Contact Lens Dropouts
Contact lens (CL) discomfort is a complex phenomenon that has been defined by the Tear Film and Ocular Surface Society (TFOS) in their seminal report on CL discomfort as a condition that results in "episodic or persistent adverse…
- Conditions
- Dry Eye, Contact Lens Complication, Contact Lenses
- Trial name
- T30DO (NCT06967298)
- Testing
- T30 Contact lenses
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Dry Eye Syndromes
A Pilot Study on the Use of a Sensory Panel to Assess Comfort Between Three Different Contact Lenses
As new contact lens products continue to be developed and improved, it's becoming harder for some individuals to tell whether one product is different from another.
- Trial name
- NAISMITH (NCT01840787)
- Testing
- balafilcon A (8.6), balafilcon A (8.3), senofilcon A
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Dry Eye, Contact Lens Complication
Direct Application of Systane Complete to Contact Lenses
A common first line treatment for patients with dryness symptoms or contact lens discomfort is the application of artificial tears or rewetting drops, respectively.
- Trial name
- NCT03848221
- Testing
- Systane Complete, Sensitive Eyes Rewetting Drops
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- University of Alabama at Birmingham
Dry Eye
Clinical Evaluation of a Multidose Preservative-free Lubricating Eye Drops Contained in Novelia® Eye Dropper in Non-Contact Lens Wearing Patients
This is a 30-Day, multi-site, single-masked, bilateral, active- controlled, 2-Arm parallel group study to evaluate the safety and efficacy of an Investigational product.
- Trial name
- NCT05661851
- Testing
- Investigational Lubricating Eye Drop in a Novelia® bottle, Blink® Tears eye Drops
- Where
- 8 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Dry Eyes
Effect of Contact Lens With Alginic Acid in Dry Eye Patients
Contact lens induced dry eyes leads to lens intolerance and discontinuation. Incidence of dry eye in contact lens wearer is significantly higher in Asian population compared to other ethnic group considering Asian has lower tear…
- Trial name
- NCT01918410
- Testing
- Contact Lens with alginic acid, Contact Lens without alginic acid
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Louis Tong
Dry Eye
Investigating iLux Efficacy in Contact Lens Wearers With Evaporative Dry Eye Disease
The purpose of this clinical trial is to investigate the efficacy of a single iLux® treatment in symptomatic CL wearers who have DED (according to the TFOS DEWS II diagnostic criteria), of the evaporative dry eye disease subtype…
- Trial name
- SHEEPDOG (NCT04159935)
- Testing
- iLux® system
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Keratoconus, Dry Eye
Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Keratoconus
Drug delivery platforms are an innovative exciting advancement in ophthalmology. They allow patients to eliminate topical medications which are generally associated with lack of compliance, difficulty of use and requiring help…
- Conditions
- Keratoconus, Dry Eye, Allergy
- Trial name
- NCT04418999
- Testing
- dexamethasone ophthalmic insert 0.4 mg, for intracanalicular use, Loteprednol Etabonate 0.38% Ophthalmic Gel/Jelly
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Illinois College of Optometry