Clinical trials: Contact Lens Dry Eye
Dry Eye
A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear
Assess the impact of concomitant Miebo use while wearing contact lenses
- Trial name
- NCT07054606
- Testing
- Perfluorohexyloctane ophthalmic solution
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye, Contact Lens Complication
Dailies Total 1 Sphere Contact Lenses
CL discomfort is a complex phenomenon that has been defined by the Tear Film and Ocular Surface Society in their seminal report on contact lens (CL) discomfort as a condition that results in "episodic or persistent adverse ocular…
- Trial name
- NCT05239494
- Testing
- DT1 Sphere Contact Lenses
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Contact Lens Complication, Dry Eye
Total30 Sphere Contact Lenses
The purpose of this study is to map comfort over the full wear day in established, asymptomatic, soft CL wearers who are refit in Total30 Sphere CLs.
- Trial name
- NCT05183022
- Testing
- Total30 Sphere Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Myopia, Dry Eye
Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber
The purpose of this study is to evaluate two different types of contact lenses and their effect on dry eyes when compared to wearing glasses in a controlled, low humidity chamber.
- Trial name
- NCT01482312
- Testing
- lotrafilcon A contact lenses, comfilcon A contact lenses, Glasses
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- CIBA VISION
Dry Eye Syndromes, Meibomian Gland Dysfunction
The Effect of Tear Supplements on Contact Lens Comfort
The primary goal of this investigation is to determine if lipid based artificial tear supplementation has an impact on contact lens discomfort (CLD).
- Trial name
- NCT02956083
- Testing
- Systane Balance eye drops, Systane Contacts eye drops, saline
- Volunteers
- 30 people
- Sponsor
- University of the Incarnate Word
Dry Eye, Dry Eye Syndromes
Assessment of Tear Production, Corneal Staining, and Comfort Level Wearing Different Types of Contact Lenses
This research assesses the tear performance of five distinct types of soft contact lenses commonly found in the market. The study involves contact lens participants, all of whom are students enrolled at UKM.
- Conditions
- Dry Eye, Dry Eye Syndromes, Contact Lens-induced Corneal Fluorescein Staining
- Trial name
- NCT06351410
- Testing
- Eye Wearing Contact Lens
- Where
- Malaysia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Dry Eye
Evaluation of Comfort of Ocular Lubricants in Symptomatic Contact Lens Wearers
The purpose of this study is to evaluate the ocular comfort of 3 ocular lubricants and a comparator.
- Trial name
- NCT05741216
- Testing
- OTF Ocular Lubricant, Ocular Lubricant
- Where
- 3 sites in Australia, Canada
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Contact Lens Discomfort, Dry Eye
Evaluation of Systane Complete for the Treatment of Contact Lens Discomfort
Clinicians commonly use artificial tears off label for treating contact lens (CL) discomfort and the dry eye associated with CLs because new artificial tear formulations have the potential to outperform the available CL rewetting…
- Trial name
- NCT03682809
- Testing
- Systane Complete
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Dry Eye Syndrome
Assessment of Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Subjects While Wearing Contact Lenses and Before Insertion of Contact Lenses
The "dry eye syndrome" DES is a highly prevalent ocular disease, in particular in the elderly population. One mainstay of therapy for patients suffering from DES is the use of topically administered lubricants.
- Trial name
- NCT01747616
- Testing
- Chitosan-N-acetylcysteine eye drops (concentration of 0.1%), Physiological saline solution
- Where
- Austria
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Contact Lens Related Dry Eye Syndrome
Efficacy Study of a New Eyedrop on Silicone Hydrogel Contact Lens Wearers With Dry Eye Complaints
The objectives of the investigation will be to assess the effect of the repeated usage of a new eye drop on the tear film characteristics of silicone hydrogel contact lens wearers with contact lens related comfort problems and to…
- Trial name
- NCT01543061
- Testing
- OPTIVEtm Plus, No treatment, Blink Contacts® Eye Drops
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Optometric Technology Group Ltd
Dry Eye
Safety and Efficacy of Optive in Contact Lens Wearers With Dry Eyes
The purpose of this study is to determine if Optive®eye drops are safe for people who wear contact lenses and have dry eyes. The second goal of the study is to determine if using Optive®eye drops can improve my dry eye scores on…
- Trial name
- NCT00469573
- Testing
- 1. Optive
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Cataract, Lens Subluxation
Efficacy of an Ocular Bandage Contact Lens for the Treatment of Dry Eye After Complicated and Combined Cataract Surgery
To study the efficacy of an ocular bandage contact lens for the treatment of dry eye after complicated and combined cataract surgery
- Conditions
- Cataract, Lens Subluxation, Hypermature Cataract, Corneal Opacity
- Trial name
- NCT04120389
- Testing
- bandage contact lenses(PureVision; Bausch & Lomb Inc., Rochester, NY), phacoemulsification
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Dry Eye
The Effect of Xiidra on Comfort and Dryness in Symptomatic Contact Lens Wearers
The purpose of this study to evaluate changes in comfort and dryness in symptomatic contact lens (CL) wearers after using Xiidra (lifitegrast 5.0% ophthalmic solution) for 12 weeks.
- Trial name
- COLLIE (NCT04297618)
- Testing
- Xiidra
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Stevens-Johnson Syndrome, Graft Versus Host Disease in Eye
Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease
The goal of this research is to determine if the Tangible Boost system adequately replenishes the Hydra-PEG coating on the surface of a rigid contact lens.
- Conditions
- Stevens-Johnson Syndrome, Graft Versus Host Disease in Eye, Sjogren's Syndrome, Dry Eye
- Trial name
- NCT04313725
- Testing
- Tangible Boost
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Tangible Science
Dry Eye, Contact Lens Discomfort
Contact Lens-Wearing Dry Eye Subjects Who Are Treated With Acoltremon 0.003%
Dry Eye Disease is a multifaceted condition which has symptoms such as eye dryness, burning, and stinging sensation in the eyes. As well as clinical diagnosis such as a decreased ability to create tear film.
- Conditions
- Dry Eye, Contact Lens Discomfort, Eye Drops
- Trial name
- NCT07848373
- Testing
- acoltremon 0.003%
- Volunteers
- 50 people
- Sponsor
- Eye Research Associates, LLC
Dry Eye
Lifitegrast 5% for the Treatment of Dry Eye In Habitual Soft Contact Lens Wearers
This is a prospective, single site, randomized, double masked, comparator-controlled study designed to evaluate the efficacy of lifitegrast ophthalmic solution 5% in treating the symptoms of dry eye in soft contact lens wearers…
- Trial name
- NCT05505292
- Testing
- Lifitegrast 5% Ophthalmic Solution, Lifitegrast Ophthalmic Solution Vehicle
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- State University of New York College of Optometry
Dry Eye
Optimization of Assessment and Grading for Lid Wiper Epitheliopathy
The purpose of this study is to assess eyelid margin staining, termed "lid wiper epitheliopathy" (LWE), in three populations. The hypothesis is LWE will be more prevalent in symptomatic contact lens wearers than non-symptomatic…
- Trial name
- BURNABY (NCT01611922)
- Testing
- Ophthalmic dye, Contact lenses
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens, Contact Lens Discomfort
Lifitegrast 5% Ophthalmic Solution and Contact Lens Dryness
The most common reason for contact lens discontinuation is contact lens discomfort. The investigators believe that inflammation plays a role in contact lens discomfort and the use of lifitegrast 5% ophthalmic solution may reduce…
- Conditions
- Contact Lens, Contact Lens Discomfort, Contact Lens Dryness
- Trial name
- NCT03686878
- Testing
- Lifitegrast
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- EV Clinical Trials
Contact Lens Complication, Dry Eye
Correlation Study of Corneal Nerve Changes and Dry Eye in Contact Lens Wearers
This study aims to analyze the changes of corneal nerve morphology and function in contact lens-related dry eye(CLADE) patients and further discuss the role of corneal nerve in the genesis and development of CLADE.
- Trial name
- NCT04663529
- Testing
- contact lens
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Dry Eye Disease (DED), Contact Lens Discomfort (CLD)
Treating Contact Lens Discomfort With Cyclosporine 0.1% Ophthalmic Solution
Of the 140 million contact lens (CL) wearers worldwide, most wear soft contact lenses. Despite major improvements in contact lens care, nearly 20% of wearers stop using lenses, with contact lens discomfort (CLD) being the main…
- Trial name
- NCT07904728
- Testing
- Cyclosporine 0.1% Ophthalmic Solution
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ocular Aesthetics, LLC dba Ocular Clinical Trials