Clinical trials: Contact Lens Solution
Contact Lens-induced Corneal Fluorescein Staining
Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear
The purpose of this study is to assess corneal staining and to measure the relative corneal epithelial "barrier" function (the degree to which the cornea can prevent penetration of colored sodium fluorescein dye into the eye)…
- Trial name
- NCT01015768
- Testing
- ReNu Multiplus multipurpose disinfecting solution, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Keratitis
Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision Lenses
Corneal epithelial disruption, commonly termed "corneal staining" has been frequently associated with contact lens wear. Previous research has demonstrated higher levels of observed corneal staining when certain combinations of…
- Trial name
- NCT01268306
- Testing
- B+L Biotrue MPS and B+L PureVision
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Epstein, Arthur B., OD, FAAO
Vision Disorders
Study of A New Contact Lens Cleaning and Disinfecting Solution
The objective of this study is to evaluate the safety and efficacy of a new investigational cleaning and disinfecting solution (Test) compared to Clear Care cleaning and disinfecting solution (Control) when used by contact lens…
- Trial name
- NCT01318577
- Testing
- Investigational Cleaning & Disinfecting Solution, Clear Care Solution
- Where
- United States
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Normal Contact Lens Wear
Two Phase Clinical Study of the Impact of Contact Lenses and Solutions on Corneal Structure
Assess the usefulness of using confocal microscopy to examine changes to the structure of the cornea and to identify any potential consequences of contact lens wear and/or solution use.
- Trial name
- NCT00804999
- Testing
- Clear Care, ReNu, OPTI-FREE
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Christine Sindt
Contact Lens Solutions
Evaluation of a Multi-Purpose Solution
This study evaluates a multi-purpose solution when used on a daily wear basis by currently adapted soft contact lens wearers.
- Trial name
- NCT00710879
- Testing
- Bausch & Lomb Multi-Purpose Solution
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Visual Acuity, Slit Lamp Biomicroscopy (Corneal Staining Assessment)
Clinical Evaluation of 3 Contact Lens Materials With 3 Solution Types
This is a multi-site, randomized, double-masked, contralateral, 2 treatment x 2 period crossover, dispensing, five-visit study to gain clinical insights of the study lenses and solutions.
- Trial name
- NCT03466060
- Testing
- Opti-Free : RevitaLens / Clear Care : RevitaLens, Opti-Free : RevitaLens / RevitaLens : Clear Care, Clear Care : RevitaLens/ Opti-Free : RevitaLens
- Where
- 5 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Normal Contact Lens Wearers
Comparison of a New Abbott Medical Optics (AMO) Multi-Purpose Solution (MPS) to Existing Contact Lens Regimens
Crossover clinical evaluation three contact lens care regimens used for one month with Acuvue Oasys lenses.
- Trial name
- NCT01294917
- Testing
- Multi-purpose disinfecting solution, Clear Care, Opti-Free RepleniSH
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Corneal Staining
Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
An investigational multi-purpose solution (MPS)was clinically evaluated against Biotrue MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Trial name
- NCT01240122
- Testing
- Biotrue MPS, Investigational MPS
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Contact Lens Solutions
Clinical and Laboratory Evaluation of 3 Contact Lenses With 4 Contact Lens Solutions
The purpose of this study is to evaluate the clinical and laboratory performance of three brand name contact lenses with three recently introduced multipurpose lens care solutions (test solutions) as well as a peroxide…
- Trial name
- NCT01791517
- Testing
- Solution 1 (Test), Solution 2 (Test), Solution 3 (Test)
- Where
- 3 sites in United States, Canada and 1 more
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Study Focus is Healthy Contact Lens Wearers
Evaluation of an Investigational Multi-Purpose Solution (MPS)
The purpose of this study is to evaluate the safety and effectiveness of an investigational multi-purpose contact lens solution.
- Trial name
- NCT00961051
- Testing
- Investigational MPS, Opti-Free
- Where
- 9 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Myopia, Hyperopia
One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System
The purpose of this study is to evaluate the clinical performance of the contact lens care product Oté Sensation in a representative population of soft contact lens wearers.
- Trial name
- NCT03278223
- Testing
- Test solution, Control solution
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- OTE North America
Healthy Contact Lens Wearers
Safety and Efficacy of an Investigational Multi-Purpose Disinfecting Solution
The purpose of this study is to determine if Alcon MPDS is safe and effective for silicone hydrogel and soft hydrogel contact lens wearers.
- Trial name
- NCT01341977
- Testing
- Alcon MPDS, ReNu Fresh MPS
- Where
- United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Solutions
Objective Testing of Tear Film Stability
The purpose of this study is to evaluate the in-vivo wettability of soft contact lenses when cared with two different multi-purpose solutions over a two week wearing period.
- Trial name
- NCT00789529
- Testing
- Opti-Free® RepleniSH® MPDS, ReNu MultiPlus®
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Manhattan Vision Associates