Clinical trials: Contact Lens Solution
Contact Lens Solution
Comparison of 3 Novel Contact Lens Solutions on the Basal Lamina
Three arm study comparing three novel contact lens solutions.
- Trial name
- NCT00691457
- Testing
- Opti-Free contact lens solution, ReNu Multiplus contact lens solution, Clear Care contact lens solution
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Alcon Research
Contact Lens Solution
Evaluation of Tangible Boost Replenishing System
This study will evaluate Tangible Boost, a new contact lens care product which is designed to replenish the hydrogel layer on fluorosilicone acrylate lenses with Hydra-PEG.
- Trial name
- NCT03073148
- Testing
- Tangible Boost
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Tangible Science
Contact Lens Wear
Evaluation of Silicone Hydrogel Lens Wettability With Marketed Lens Care Solutions
The purpose of this study is to assess ex vivo wettability of a commonly prescribed silicone hydrogel (SiH) contact lens with three marketed contact lens care solutions.
- Trial name
- SILVER (NCT01252134)
- Testing
- Biotrue multipurpose solution, Sauflon Synergi multipurpose solution, OTE Elements multipurpose solution
- Volunteers
- 22 people
- Sponsor
- Alcon Research
Contact Lens Complication, Debris in Post Lens Tear Reservoir
Evaluation of Contact Lens Saline Solutions With Scleral GP Contact Lens Wearers Experiencing Fogging
Evaluation of saline solutions used with scleral rigid gas permeable contact lens wearers experiencing debris in the post lens tear reservoir
- Trial name
- NCT03525704
- Testing
- Saline Solution Enriched, Saline Rinse Solution
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Myopia
A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)
The purpose of this study was to demonstrate that current successful fulltime daily wear soft contact lens wearers using competitive multi-purpose solutions will note improved comfort when using OPTI-FREE RepleniSH®.
- Trial name
- NCT00772707
- Testing
- Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH), Contact Lenses
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Myopia, Hyperopia
Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 1
The purpose of this study was to evaluate the performance of Opti-Free® PureMoist® Multi-Purpose Disinfecting Solution (MPDS) compared to Biotrue™ Multipurpose Solution (MPS) in silicone hydrogel contact lens wearers.
- Conditions
- Myopia, Hyperopia, Contact Lens Comfort
- Trial name
- NCT01684033
- Testing
- Opti-Free® PureMoist® MPDS, Biotrue™ MPS, Habitual contact lenses
- Volunteers
- 207 people
- Sponsor
- Alcon Research
Normal Contact Lens Wearers
Comparison of a New Abbott Medical Optics (AMO) Multi-Purpose Solution (MPS) to Existing Contact Lens Regimens
Crossover clinical evaluation three contact lens care regimens used for one month with Acuvue Oasys lenses.
- Trial name
- NCT01294917
- Testing
- Multi-purpose disinfecting solution, Clear Care, Opti-Free RepleniSH
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Myopia, Astigmatism
Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers
The purpose of this study was to assess the comfort of OPTI-FREE RepleniSH in soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01211535
- Testing
- OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Contact Lens Disinfecting Solutions
Comparison of Two Multi-Purpose Solution and Lens Material Combinations on Corneal Barrier Function
The purpose of this study is to measure the relative "barrier" function of the top layer of the cornea (called the epithelium), or the degree to which the cornea can prevent the penetration of the colored dye sodium fluorescein…
- Trial name
- NCT00560898
- Testing
- ProClear Lens Material soaked in ReNu Multiplus Multipurpose Solution, Acuvue Advance Lens Material soaked in ReNu Multiplus Multipurpose Solution, Acuvue Advance Lens Material soaked in Optifree RepleniSH Multipurpose Solution
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Contact Lens Care
Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Silicone Hydrogel Soft Contact Lenses
The objective of the study was to clinically evaluate the safety and effectiveness of a new multi-purpose disinfecting solution in patients wearing silicone hydrogel soft contact lenses.
- Trial name
- NCT00382902
- Testing
- OptiFree Multi-Purpose Disinfecting Solution
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Moisture
Effect of an Investigational Multi-Purpose Solution on Lens Moisture
The purpose of the study is to evaluate the effect of an investigational multi-purpose disinfecting solution (MPDS) compared to a marketed multi-purpose solution on the moisture of silicone hydrogel contact lenses.
- Trial name
- NCT01341990
- Testing
- FID 114675A Multi-Purpose Disinfecting Solution (MPDS), ReNu Fresh Lens Comfort Multi-Purpose Solution (MPS), Silicone Hydrogel Contact Lenses
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
The purpose of this study is to evaluate the lipid uptake, wetting characteristics, and visual performance of AIR OPTIX® AQUA and ACUVUE® OASYS® with HYDRACLEAR® contact lenses when used in conjunction with two contact lens care…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01699750
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE® PUREMOIST® MPDS
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Alcon Research
Contact Lens Solutions
Safety and Efficacy of a Bausch & Lomb Multipurpose Solution When Compared to Ciba Vision Aquify Multipurpose Solution
To the safety and efficacy of a Bausch \& Lomb Multipurpose Solution when compared to Ciba vision Aquify Multipurpose solution
- Trial name
- NCT00636363
- Testing
- Bausch & Lomb Multipurpose Solution - Rub Care, Bausch & Lomb Multipurpose Solution - No Rub Care, Ciba Vision Aquify Multipurpose Solution
- Where
- United States
- Volunteers
- 541 people
- Sponsor
- Bausch & Lomb Incorporated
Contact Lens Wearer
2-Hour Dispensing Evaluation of Samfilcon A Lenses With EPG01 Packaging Solution Compared to Commercially Available B+L Ultra Lenses
The objective of this 2 hour study is to evaluate the clinical performance of samfilcon A lenses with an alternate packaging solution (EPG01) compared to commercially available B+L Ultra lenses.
- Trial name
- NCT05126953
- Testing
- samfilcon A Lenses with EPG01 Packaging Solution, Commercially Available B+L Ultra Lenses
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Bausch & Lomb Incorporated
Contact Lens-induced Corneal Fluorescein Staining
Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear
The purpose of this study is to assess corneal staining and to measure the relative corneal epithelial "barrier" function (the degree to which the cornea can prevent penetration of colored sodium fluorescein dye into the eye)…
- Trial name
- NCT01015768
- Testing
- ReNu Multiplus multipurpose disinfecting solution, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Refractive Error
Clear Care® Plus vs. PeroxiClear™
The purpose of this study is to evaluate Clear Care® Plus compared to PeroxiClear™ for mean residual peroxide in used lens cases collected at Day 30 after neutralization at recommended storage time.
- Trial name
- NCT02413333
- Testing
- Clear Care Plus contact lens solution, PeroxiClear contact lens solution, Silicone hydrogel contact lenses
- Volunteers
- 133 people
- Sponsor
- Alcon Research
Contact Lens Care
Single Site Study of the Wettability of Contact Lenses With an Investigational Multi-Purpose Disinfecting Solution vs. a Marketed Multi-Purpose Solution
The purpose of this study is to clinically evaluate an investigational multi-purpose disinfecting solution (MPDS) compared to a commercial MPDS with respect to wettability of silicone hydrogel contact lenses.
- Trial name
- NCT00885092
- Testing
- FID 114675A Multi-Purpose Disinfecting Solution (MPDS), RepleniSH Multi-Purpose Disinfecting Solution (MPDS) (OPTI-FREE® RepleniSH®), Senofilcon A contact lens (ACUVUE® Oasys™)
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Adverse Effect of Contact Lens Solution
Comparative Performance of a Bausch & Lomb Multipurpose Solution and Alcon OptiFree Replenish Multipurpose Solution
To evaluate the product performance of a Bausch \& Lomb Multipurpose solution when compared to Alcon OptiFree Replenish Multipurpose Solution
- Trial name
- NCT00636194
- Testing
- Bausch & Lomb Multipurpose Solution, Alcon OptiFree Replenish Multipurpose Solution
- Where
- Malaysia
- Volunteers
- 361 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Hyperopia
Multipurpose Disinfecting Solution Compatibility With a Silicone Hydrogel Contact Lens
The purpose of this study is to verify the compatibility of a silicone hydrogel lens when used with four multipurpose disinfecting solutions (OPTI-FREE® RepleniSH®, ReNu MultiPlus®, Solo-Care Aqua™ and MeniCareTM Soft).
- Trial name
- Amethyst (NCT00520689)
- Testing
- Silicone Hydrogel Contact Lens
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia, Hyperopia
Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 2
The purpose of this study was to evaluate the performance of Opti-Free® PureMoist® Multi-purpose Disinfecting Solution (MPDS) compared to AMO RevitaLens OcuTec® MPDS (US brand name)/COMPLETE RevitaLens (Europe brand name) in…
- Conditions
- Myopia, Hyperopia, Contact Lens Comfort
- Trial name
- NCT01684046
- Testing
- Opti-Free® PureMoist® MPDS, RevitaLens MPDS, Habitual Contact Lenses
- Volunteers
- 196 people
- Sponsor
- Alcon Research