Clinical trials: Contact Lens Solutions
Symptomatic Contact Lens Wearers
Alcon Multi-Purpose Disinfecting Solution Versus Renu Fresh Multi-Purpose Solution in Symptomatic Contact Lens Wearers
The purpose of this study is to compare two contact lens care solutions in symptomatic wearers of silicone hydrogel contact lenses.
- Trial name
- NCT01187355
- Testing
- FID 114675A Multi-Purpose Disinfecting Solution (MPDS), renu fresh Multi-Purpose Solution (MPS), Contact lenses
- Where
- United States
- Volunteers
- 591 people
- Sponsor
- Alcon Research
Normal Contact Lens Wearers
Comparison of a New Abbott Medical Optics (AMO) Multi-Purpose Solution (MPS) to Existing Contact Lens Regimens
Crossover clinical evaluation three contact lens care regimens used for one month with Acuvue Oasys lenses.
- Trial name
- NCT01294917
- Testing
- Multi-purpose disinfecting solution, Clear Care, Opti-Free RepleniSH
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Patient Comfort, Lens Cleanliness
Comfort and Cleaning Evaluation of Multipurpose Solutions in Contact Lens Patients
To compare patient comfort and overall lens cleanliness with consecutive use of two multipurpose lens solutions.
- Trial name
- NCT00519948
- Testing
- new MPS, opti-free express no rub MPS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Innovative Medical
Healthy Contact Lens Wearers
Safety and Efficacy of an Investigational Multi-Purpose Disinfecting Solution
The purpose of this study is to determine if Alcon MPDS is safe and effective for silicone hydrogel and soft hydrogel contact lens wearers.
- Trial name
- NCT01341977
- Testing
- Alcon MPDS, ReNu Fresh MPS
- Where
- United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Care
Single Site Study of the Wettability of Contact Lenses With an Investigational Multi-Purpose Disinfecting Solution vs. a Marketed Multi-Purpose Solution
The purpose of this study is to clinically evaluate an investigational multi-purpose disinfecting solution (MPDS) compared to a commercial MPDS with respect to wettability of silicone hydrogel contact lenses.
- Trial name
- NCT00885092
- Testing
- FID 114675A Multi-Purpose Disinfecting Solution (MPDS), RepleniSH Multi-Purpose Disinfecting Solution (MPDS) (OPTI-FREE® RepleniSH®), Senofilcon A contact lens (ACUVUE® Oasys™)
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Contact Lenses
A Clinical Comparison of Three Contact Lens Care Systems and Their Effect on Contact Lenses
The purpose of this study was to evaluate the clinical performance of three differing contact lens care solutions when used in conjunction with three contact lenses.
- Trial name
- NCT00982046
- Testing
- Opti-Free RepleniSH multi-purpose disinfecting solution, ReNu MultiPlus multi-purpose solution, Clear Care cleaning and disinfecting system
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- Alcon Research
Study Focus is Healthy Contact Lens Wearers
Evaluation of an Investigational Multi-Purpose Solution (MPS)
The purpose of this study is to evaluate the safety and effectiveness of an investigational multi-purpose contact lens solution.
- Trial name
- NCT00961051
- Testing
- Investigational MPS, Opti-Free
- Where
- 9 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Contact Lens Dry Eye
A Four Week Study of Azithromycin Ophthalmic Solution, 1% Versus Rewetting Drops in Subjects With History and Current Complaint of Contact Lens-Related Dry Eye (CLDE)
The primary objective of this study is to compare the duration of subject reported comfortable contact lens daily wear time in subjects with a history and current complaint of CLDE during a 29-day treatment period of azithromycin…
- Trial name
- NCT01105624
- Testing
- azithromycin ophthalmic solution, 1%, Visine® for Contacts®
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Merck Sharp & Dohme LLC
Contact Lens Care
Effect of Multi-Purpose Solutions on Ex-Vivo Wetting Angles
To clinically evaluate the effect of a new multi-purpose disinfecting solution compared to a marketed multi-purpose solution on wettability of soft contact lenses worn for 30 days.
- Trial name
- NCT00383201
- Testing
- OptiFree Multi-Purpose Disinfecting Solution
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Solutions
A Range of Contact Lenses and Care System Combinations
The objective of this study is to compare the short-term clinical response to all combinations of two lens types: fanfilcon A and comfilcon A with two care systems: Hy-Care and Lite.
- Trial name
- NCT03632083
- Testing
- Hy-Care Contact Lens Solution, Lite Contact Lens Solution, fanfilcon A soft contact lens
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- CooperVision, Inc.
Contact Lens Wearer
Biotrue ONEday Contact Lenses With EPG03 Packaging Solution Compared to Biotrue ONEday Contact Lenses
The objective of this 2 hour study is to evaluate the clinical performance of Biotrue ONEday lenses with an alternate packaging solution (EPG03) compared to commercially available Biotrue ONEday lenses.
- Trial name
- NCT05129488
- Testing
- All participants received Biotrue ONEday lenses with and without an alternate packaging solution (EPG03)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error, Myopia
Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
The purpose of this study was to compare lens comfort on Day 30 for Air Optix® lenses cared for with OPTI-FREE® PureMoist® (OFPM) Multi Purpose Disinfecting Solution (MPDS) compared to Acuvue® Oasys® lenses cared for with…
- Conditions
- Refractive Error, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01809197
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)
- Volunteers
- 387 people
- Sponsor
- Alcon Research
Contact Lens Wettability
Effect of FID 114675A on Lens Wettability
The purpose of this study is to evaluate lens wettability of contact lenses when used with an investigational multi-purpose disinfecting solution.
- Trial name
- NCT01342107
- Testing
- FID 114675A multi-purpose disinfecting solution (MPDS), Soft contact lens, Blister pack solution
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Alcon Research
Contact Lens Care
Evaluation of an Investigational Multi-Purpose Disinfecting Solution for Care of Soft Contact Lenses
The objective of the study was to clinically evaluate the safety and effectiveness of a new multi-purpose disinfecting solution for soft contact lenses.
- Trial name
- NCT00382681
- Testing
- FID 107027 Multi-Purpose Disinfecting Solution, ReNu MultiPlus Multi-Purpose Solution No Rub Formula
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Fit, Myopia
Clinical Performance of a Silicone Hydrogel Lens With Use of FID 114675A
The purpose of this study is to evaluate the clinical performance of a silicone hydrogel contact lens when used with an investigational multi-purpose disinfecting solution (MPDS).
- Trial name
- NCT01240135
- Testing
- FID 114675A multi-purpose disinfecting solution (MPDS), renu fresh Multi-Purpose Solution (MPS), Galyfilcon A contact lenses (Acuvue Advance)
- Volunteers
- 89 people
- Sponsor
- Alcon Research
Vision
Wettability of Contact Lenses With a Multi-Purpose Solution
Measure wettability of hydrogel and silicone hydrogel contact lenses presoaked in a Multi-Purpose Solution.
- Trial name
- NCT00713076
- Testing
- Polyquaternium-preserved Multi-purpose Lens Cleaning Solution 109182
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Myopia
A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)
The purpose of this study was to demonstrate that current successful fulltime daily wear soft contact lens wearers using competitive multi-purpose solutions will note improved comfort when using OPTI-FREE RepleniSH®.
- Trial name
- NCT00772707
- Testing
- Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH), Contact Lenses
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Healthy
Lens Wearing Experience and Biocompatibility of a Multi-Purpose Disinfecting Solution (MPDS)
The purpose of this study was to evaluate the efficacy of a new multipurpose disinfecting solution in silicone hydrogel and soft contact lens wearers.
- Trial name
- NCT01476722
- Testing
- OPTI-FREE PureMoist multipurpose disinfecting solution
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Alcon Research
Dry Eye, Dry Eye Syndromes
Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye
Tangible Hydra-PEG is a novel coating technology designed to improve lens wettability, deposit resistance, and tear film breakup time.
- Trial name
- NCT03417505
- Testing
- Scleral lenses treated with Tangible Hydra-PEG, Untreated scleral lenses
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Tangible Science
Contact Lens Solution
Comparison of 3 Novel Contact Lens Solutions on the Basal Lamina
Three arm study comparing three novel contact lens solutions.
- Trial name
- NCT00691457
- Testing
- Opti-Free contact lens solution, ReNu Multiplus contact lens solution, Clear Care contact lens solution
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Alcon Research