Clinical trials: Contact Lens Solutions
Contact Lens Complication, Debris in Post Lens Tear Reservoir
Evaluation of Contact Lens Saline Solutions With Scleral GP Contact Lens Wearers Experiencing Fogging
Evaluation of saline solutions used with scleral rigid gas permeable contact lens wearers experiencing debris in the post lens tear reservoir
- Trial name
- NCT03525704
- Testing
- Saline Solution Enriched, Saline Rinse Solution
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Contact Lens Dry Eye
Use of 5.0% Lifitegrast Ophthalmic Solution for the Treatment of Dry Eye Disease in Contact Lens Wearers
Discomfort with contact lens wear is the biggest reason why people stop wearing contact lenses. The investigators believe that inflammation is one of the causes of discomfort, and by blocking the inflammation using lifitegrast…
- Trial name
- NCT03431272
- Testing
- Lifitegrast
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Contact Lens Wearer
2-Hour Dispensing Evaluation of Samfilcon A Lenses With EPG01 Packaging Solution Compared to Commercially Available B+L Ultra Lenses
The objective of this 2 hour study is to evaluate the clinical performance of samfilcon A lenses with an alternate packaging solution (EPG01) compared to commercially available B+L Ultra lenses.
- Trial name
- NCT05126953
- Testing
- samfilcon A Lenses with EPG01 Packaging Solution, Commercially Available B+L Ultra Lenses
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Bausch & Lomb Incorporated
Contact Lens Solutions
Safety and Efficacy of a Bausch & Lomb Multipurpose Solution When Compared to Ciba Vision Aquify Multipurpose Solution
To the safety and efficacy of a Bausch \& Lomb Multipurpose Solution when compared to Ciba vision Aquify Multipurpose solution
- Trial name
- NCT00636363
- Testing
- Bausch & Lomb Multipurpose Solution - Rub Care, Bausch & Lomb Multipurpose Solution - No Rub Care, Ciba Vision Aquify Multipurpose Solution
- Where
- United States
- Volunteers
- 541 people
- Sponsor
- Bausch & Lomb Incorporated
Contact Lens Care
OPTI-FREE Family STUDY
The purpose of this post-market clinical follow-up (PMCF) study is to evaluate the long-term safety and performance of 3 commercially available contact lens cleaning and disinfecting solutions in a pediatric population.
- Trial name
- NCT06592521
- Testing
- OPTI-FREE EXPRESS MPDS and Alcon contact lens case, OPTI-FREE PureMoist MPDS and Alcon contact lens case, OPTI-FREE REPLENISH MPDS and Alcon contact lens case
- Where
- United States
- Sponsor
- Alcon Research
Myopia, Hyperopia
Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 1
The purpose of this study was to evaluate the performance of Opti-Free® PureMoist® Multi-Purpose Disinfecting Solution (MPDS) compared to Biotrue™ Multipurpose Solution (MPS) in silicone hydrogel contact lens wearers.
- Conditions
- Myopia, Hyperopia, Contact Lens Comfort
- Trial name
- NCT01684033
- Testing
- Opti-Free® PureMoist® MPDS, Biotrue™ MPS, Habitual contact lenses
- Volunteers
- 207 people
- Sponsor
- Alcon Research
Contact Lens Solution Toxicity
Efficacy and Safety of cleadewGP for Rigid Contact Lenses
Multipurpose solutions (MPS) are the most commonly prescribed regimen to clean, disinfect and rinse rigid lenses. The preservatives used in MPS may cause hypersensitivity and the presence of quaternary ammonium compounds (QAC)…
- Trial name
- NCT03193255
- Testing
- OPHTECS cleadew GP
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Visual Acuity, Slit Lamp Biomicroscopy (Corneal Staining Assessment)
Clinical Evaluation of 3 Contact Lens Materials With 3 Solution Types
This is a multi-site, randomized, double-masked, contralateral, 2 treatment x 2 period crossover, dispensing, five-visit study to gain clinical insights of the study lenses and solutions.
- Trial name
- NCT03466060
- Testing
- Opti-Free : RevitaLens / Clear Care : RevitaLens, Opti-Free : RevitaLens / RevitaLens : Clear Care, Clear Care : RevitaLens/ Opti-Free : RevitaLens
- Where
- 5 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Wear
A Safety and Effectiveness Study of a New Contact Lens Cleaning and Disinfecting Solution
The objective of this study is to evaluate the safety and effectiveness of NNR06 Multi-Purpose Solution cleaning and disinfecting solution (Test) compared to COMPLETE Multi-Purpose Solution cleaning and disinfecting solution…
- Trial name
- NCT02701556
- Testing
- Complete MPS, NNR06
- Where
- United States
- Volunteers
- 396 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
An Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
The purpose of this study was to assess and compare the effect of the repeated usage of 2 different care systems (one hydrogen peroxide based cleaning and disinfecting system and one PHMB containing multipurpose system) with…
- Trial name
- ID11-56 (NCT01594294)
- Testing
- AOSEPT® Plus contact lens solution, ReNu MultiPlus® contact lens solution, Etafilcon A contact lenses
- Volunteers
- 100 people
- Sponsor
- Alcon Research
Contact Lens Care
Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
The purpose of this study was to assess and compare the effect of the repeated usage of two different contact lens care systems (one hydrogen peroxide-based cleaning and disinfecting system, and one polyaminopropyl biguanide…
- Trial name
- NCT01494818
- Testing
- Hydrogen peroxide-based contact lens care system, PHMB-containing contact lens solution, Soft contact lenses
- Volunteers
- 79 people
- Sponsor
- Alcon Research
Symptomatic Contact Lens Wearers
Alcon Multi-Purpose Disinfecting Solution Versus Renu Fresh Multi-Purpose Solution in Symptomatic Contact Lens Wearers
The purpose of this study is to compare two contact lens care solutions in symptomatic wearers of silicone hydrogel contact lenses.
- Trial name
- NCT01187355
- Testing
- FID 114675A Multi-Purpose Disinfecting Solution (MPDS), renu fresh Multi-Purpose Solution (MPS), Contact lenses
- Where
- United States
- Volunteers
- 591 people
- Sponsor
- Alcon Research
Dry Eye
Treating Contact Lens Discomfort With Varenicline Solution Nasal Spray 0.03mg
The objective of this study is to evaluate whether twice-daily use of Tyrvaya improves contact lens comfort in contact lens wearers.
- Trial name
- NCT07705893
- Testing
- Tyrvaya
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ocular Aesthetics, LLC dba Ocular Clinical Trials
Normal Contact Lens Wearers
Comparison of a New Abbott Medical Optics (AMO) Multi-Purpose Solution (MPS) to Existing Contact Lens Regimens
Crossover clinical evaluation three contact lens care regimens used for one month with Acuvue Oasys lenses.
- Trial name
- NCT01294917
- Testing
- Multi-purpose disinfecting solution, Clear Care, Opti-Free RepleniSH
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Allergic Conjunctivitis
Use of BEPREVE (Bepotastine Besilate Ophthalmic Solution) 1.5% for Allergic Conjunctivitis and Contact Lenses
The purpose of this study is to assess if BEPREVE (bepotastine besilate ophthalmic solution) 1.5% will have an effect on contact lens wear in patients with contact lens intolerance due to allergic conjunctivitis.
- Trial name
- NCT01337557
- Testing
- Bepotastine
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hom, Milton M., OD, FAAO
Contact Lens Solutions
Objective Testing of Tear Film Stability
The purpose of this study is to evaluate the in-vivo wettability of soft contact lenses when cared with two different multi-purpose solutions over a two week wearing period.
- Trial name
- NCT00789529
- Testing
- Opti-Free® RepleniSH® MPDS, ReNu MultiPlus®
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Manhattan Vision Associates
Patient Comfort, Lens Cleanliness
Comfort and Cleaning Evaluation of Multipurpose Solutions in Contact Lens Patients
To compare patient comfort and overall lens cleanliness with consecutive use of two multipurpose lens solutions.
- Trial name
- NCT00519948
- Testing
- new MPS, opti-free express no rub MPS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Innovative Medical
Myopia, Hyperopia
Multipurpose Disinfecting Solution Compatibility With a Silicone Hydrogel Contact Lens
The purpose of this study is to verify the compatibility of a silicone hydrogel lens when used with four multipurpose disinfecting solutions (OPTI-FREE® RepleniSH®, ReNu MultiPlus®, Solo-Care Aqua™ and MeniCareTM Soft).
- Trial name
- Amethyst (NCT00520689)
- Testing
- Silicone Hydrogel Contact Lens
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Healthy Contact Lens Wearers
Safety and Efficacy of an Investigational Multi-Purpose Disinfecting Solution
The purpose of this study is to determine if Alcon MPDS is safe and effective for silicone hydrogel and soft hydrogel contact lens wearers.
- Trial name
- NCT01341977
- Testing
- Alcon MPDS, ReNu Fresh MPS
- Where
- United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Care
Single Site Study of the Wettability of Contact Lenses With an Investigational Multi-Purpose Disinfecting Solution vs. a Marketed Multi-Purpose Solution
The purpose of this study is to clinically evaluate an investigational multi-purpose disinfecting solution (MPDS) compared to a commercial MPDS with respect to wettability of silicone hydrogel contact lenses.
- Trial name
- NCT00885092
- Testing
- FID 114675A Multi-Purpose Disinfecting Solution (MPDS), RepleniSH Multi-Purpose Disinfecting Solution (MPDS) (OPTI-FREE® RepleniSH®), Senofilcon A contact lens (ACUVUE® Oasys™)
- Volunteers
- 40 people
- Sponsor
- Alcon Research