Clinical trials: Contact Lens Wear
Myopia
Clinical Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens
The purpose of this study is to assess the clinical performance of an investigational contact lens over 30 days of daily wear.
- Trial name
- NCT04476784
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 66 people
- Sponsor
- Alcon Research
Dry Eye
A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear
Assess the impact of concomitant Miebo use while wearing contact lenses
- Trial name
- NCT07054606
- Testing
- Perfluorohexyloctane ophthalmic solution
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- Bausch & Lomb Incorporated
Contact Lens Wear
A Safety and Effectiveness Study of BL-ABT12 Multi-Purpose Solution for Use by Participants With Soft Contact Lenses
This study is to evaluate the safety and effectiveness of ABT12 Multi-Purpose solution (Test) compared to COMPLETE® Multi-Purpose Solution Easy Rub® Formula ("COMPLETE Multi-Purpose Solution") when used by participants who are…
- Trial name
- NCT03897751
- Testing
- ABT12 Multi-Purpose Solution, COMPLETE Multi-Purpose Solution, Sensitive Eyes® Rewetting Drops
- Where
- 17 sites in United States
- Volunteers
- 252 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Errors
Air Optix® Night and Day® Aqua Continuous Wear
The purpose of this retrospective, Post-Market Clinical Follow-Up (PMCF) study is to assess the long term performance and safety of Air Optix® Night and Day® Aqua (AONDA) contact lenses in a real-world setting when worn as 30…
- Trial name
- NCT05992675
- Testing
- Lotrafilcon A contact lenses, Balafilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 1,256 people
- Sponsor
- Alcon Research
Ametropia
Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear
Testing the Safety and Acceptability of Using a Rewetting Drop with Contact Lenses
- Trial name
- NCT00691197
- Testing
- Carboxymethylcellulose sodium and Glycerin, Carboxymethylcellulose sodium
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Allergan
Refractive Error
Clinical Performance of a Silicone Hydrogel for Daily Disposable Wear
The purpose of this study is to compare the visual acuity of an investigational silicone hydrogel to a commercially available silicone hydrogel in contact lens wearers.
- Trial name
- NCT03095027
- Testing
- FID122819 contact lenses, Stenfilcon A contact lenses
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Astigmatism
Performance of Two Toric Silicone Hydrogel Contact Lenses
Prospective study to evaluate the clinical performance of fanfilcon A toric contact lens and senofilcon A toric contact lens after two weeks of wear.
- Trial name
- NCT03578926
- Testing
- fanfilcon A toric lens, senofilcon A toric lens
- Where
- Mexico
- Volunteers
- 45 people
- Sponsor
- CooperVision, Inc.
Myopia
Acute Clinical Evaluation of Multi-purpose Solutions (MPS) in Soft Contact Lens Wearers
The purpose of this study was to clinically evaluate lens care solutions used with soft contact lenses.
- Trial name
- NCT00929487
- Testing
- Contact lens multi-purpose solution, Saline/blister pack solution, Contact lenses
- Where
- United Kingdom
- Volunteers
- 278 people
- Sponsor
- Alcon Research
Contact Lenses
Subjective and Conjunctival Response to Edge Design of Different Silicone Hydrogels
The purpose of this study was to evaluate the effect of different contact lens edge designs on the circumlimbal conjunctiva.
- Trial name
- NCT00940459
- Testing
- Senofilcon A contact lens (Acuvue Oasys), Comfilcon A contact lens (Biofinity), Lotrafilcon B contact lens (Air Optix)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Myopia
A One-Week Crossover Dispensing Evaluation of New Daily Wear Soft Contact Lenses
The purpose of this study is to validate the clinical performance of a new contact lens design when worn over a period 1 week compared to nelfilcon A (control).
- Trial name
- NCT03306641
- Testing
- Test Contact Lens, Nelfilcon A
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- CooperVision, Inc.
Myopia
Silicone Hydrogel Soft Contact Lens 7-Day Extended Wear Basis
The objective of this study is to evaluate the safety and effectiveness of the Bausch + Lomb samfilcon A soft (hydrophilic) contact lens, a new silicone hydrogel contact lens, compared to the Bausch + Lomb PureVision® soft…
- Trial name
- NCT02939950
- Testing
- Bausch + Lomb Samfilcon A Soft Contact Lens, Bausch + Lomb Pure Vision Soft Contact Lens
- Where
- United States
- Volunteers
- 816 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Contact Lens Wear
A Safety and Effectiveness Study of a New Multi-Purpose Contact Lens Care Solution
The objective of this study is to evaluate the safety and effectiveness of ASP-57 Multi-Purpose contact lens solution (Test) compared to ReNu® Multiplus Contact Lens Solution (Control) when used by habitual contact lens wearers…
- Trial name
- NCT03537248
- Testing
- ASP-57, ReNu® Multiplus
- Where
- 14 sites in United States
- Volunteers
- 315 people
- Sponsor
- Asepticys LLC
Lapsed Contact Lens Wear
Clinical Evaluation of Lapsed Contact Lens Wearers Who Are Re-fit Into Senofilcon A Contact Lenses
This study is an open-label, multi-site study. The total number of subjects was 200. The duration of this study was approximately four weeks.
- Trial name
- NCT01990664
- Testing
- senofilcon A, senofilcon A for Astigmatism
- Where
- 10 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Wear
Investigational Multi-purpose Contact Lens Care Solution.
This study compares an investigational contact lens care multi-purpose solution to a currently marketed multi-purpose solution.
- Trial name
- NCT01055613
- Testing
- Vistakon Investigational Multi-Purpose Solution I, ReNu MultiPlus Multi-Purpose Solution
- Where
- 15 sites in United States
- Volunteers
- 312 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
White Blood Cells
Study of the Cell Response in the Tear Film After Overnight Contact Lens Wear
The purpose of this study was to count and analyze the white blood cells in tear samples collected from study participants following sleep.
- Trial name
- CORNWALL (NCT01379768)
- Testing
- Lotrafilcon A contact lens, Lotrafilcon B contact lens, Clear Care Cleaning and Disinfection Solution
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- CIBA VISION
Astigmatism
Refitting Somofilcon A Toric Contact Lens Wearers Into Fanfilcon A Toric Lenses for 4-weeks of Wear
The aim of this prospective study is to evaluate the clinical performance of habitual wearers of Clariti Toric lenses after a refit with Avaira Vitality Toric lenses for 1-month of daily wear.
- Trial name
- NCT04050605
- Testing
- somofilcon A toric contact lens, fanfilcon A toric contact lens
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- CooperVision, Inc.
Ametropia
Study of Soft Contact Lens Use With 7 Day Extended Wear
To compare the safety and efficacy of the CVI silicone-hydrogel lens worn on an extended wear basis for a period of up to 7 days and 6 nights with the Acuvue 2 soft contact lenses.
- Trial name
- NCT00597467
- Testing
- VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
- Where
- 23 sites in United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Dry Eye and Contact Lens Wear
Evaluation of Corneal Epithelial Thickness Mapping
Optovue has developed a new feature for mapping corneal epithelial thickness. The purpose of the study is to evaluate the accuracy and repeatability of the epithelial thickness measurement.
- Trial name
- NCT01712022
- Where
- 3 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Optovue
Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder)
24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
The goal of this clinical trial is to learn if a new contact lens device can record patterns in eye pressure for 24 hours in adults with glaucoma and in healthy participants.
- Conditions
- Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder), Ocular Hypertension, Ocular Hypertension (OH)
- Trial name
- NCT06689696
- Testing
- miLens system
- Where
- 3 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Smartlens, Inc.
Contact Lens Wear
Compliance and Contamination in Soft Contact Lens Wearers
The purpose of this study is to assess the lens and lens case microbial colonization associated with marketed care solutions used by experienced soft lens wearers.
- Trial name
- NCT01069237
- Testing
- OPTI-FREE RepleniSH, Clear Care
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research