Clinical trials: Contact Lens Wear
Myopia
Clinical Evaluation of Stenfilcon A Soft Contact Lens When Compared to Ocufilcon B Soft Contact Lens
This study seeks to evaluate a new daily disposable contact lens compared to an existing daily disposable contact lens.
- Trial name
- NCT01354223
- Testing
- stenfilcon A contact lens, ocufilcon B contact lens
- Where
- 4 sites in United States
- Volunteers
- 90 people
- Sponsor
- CooperVision, Inc.
Astigmatism
Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear
This is a prospective, multi-site, 4-visit, bilateral, dispensing, randomized, controlled, double-masked, 2x2 crossover study to evaluate subjective comfort, overall opinion and end of day comfort following wear of two different…
- Trial name
- NCT06749496
- Testing
- Test Lens, Control Lens
- Where
- 12 sites in United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Performance and Safety of Silicone Hydrogel Soft Contact Lenses
To demonstrate substantial equivalence of the new Silicone Hydrogel Soft Contact Lenses(SHSCL) to the commercially available ACUVUE® VITA™ contact lens
- Trial name
- NCT04226560
- Testing
- 41% Silicone Hydrogel Soft Contact Lenses(SHSCL), ACUVUE® VITA™ (senofilcon C) Brand (Soft) Contact Lens, Contact Lens Care Product
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- ApexLens Co., Ltd.
Refractive Errors
Clinical Evaluation of a Daily Wear Frequent Replacement Silicone Hydrogel Lens
The purpose of this clinical study is to demonstrate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in a daily wear modality.
- Trial name
- NCT03920280
- Testing
- LID015385 contact lenses, Comfilcon A soft contact lenses, CLEAR CARE
- Where
- 8 sites in United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Ocular Physiology
Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over Two Weeks of Wear
This will be a multi-site, bilateral, dispensing, randomized, controlled, double-masked, 2×2 crossover study to evaluate ocular physiological response.
- Trial name
- NCT06161012
- Testing
- Senofilcon A contact lenses (TEST), Delefilcon A contact lenses (CONTROL)
- Where
- 6 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors
Safety and Effectiveness of the Qualis Contact Lens
Three-month, open-label, bilateral, parallel group, randomized, daily wear contact lens dispensing study.
- Trial name
- NCT04295499
- Testing
- soft (hydrophilic) contact lens
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Unicon Optical Co. Ltd.
Refractive Errors
Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations
The purpose of this study is to evaluate corneal staining observed after 2 hours of wear with an investigational contact lens against both PureVision contact lenses pre-cycled with Biotrue and Biofinity contact lenses pre-cycled…
- Trial name
- NCT04789382
- Testing
- LID018869+RepleniSH, LID018869+Biotrue, Biofinity+RepleniSH
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Adverse Effect of Contact Lens Solution
Comparative Performance of a Bausch & Lomb Multipurpose Solution and Alcon OptiFree Replenish Multipurpose Solution
To evaluate the product performance of a Bausch \& Lomb Multipurpose solution when compared to Alcon OptiFree Replenish Multipurpose Solution
- Trial name
- NCT00636194
- Testing
- Bausch & Lomb Multipurpose Solution, Alcon OptiFree Replenish Multipurpose Solution
- Where
- Malaysia
- Volunteers
- 361 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Acuity 200™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
The objective of this clinical investigation is to collect scientifically valid safety and effectiveness data on the Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear.
- Trial name
- Acuity200OK (NCT06009458)
- Testing
- Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 387 people
- Sponsor
- Acuity Polymers, Inc.
Myopia
A 6-Hour Clinical Evaluation of New Daily-Wear Soft Contact Lenses
The purpose of this study is to validate the clinical performance of a new contact lens design when worn over a period of 6 hours compared to nelfilcon A (control).
- Trial name
- NCT03235089
- Testing
- Test Lens, Control Lens
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- CooperVision, Inc.
Refractive Errors
Clinical Evaluation of a Daily Wear Monthly Replacement Silicone Hydrogel Lens
The purpose of this clinical study is to evaluate the safety and effectiveness of an investigational soft contact lens compared to a commercially available soft contact lens when worn for daily wear and replaced monthly.
- Trial name
- NCT04178720
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 8 sites in United States
- Volunteers
- 119 people
- Sponsor
- Alcon Research
Myopia
Evaluation Of One Silicone Hydrogel Contact Lens and Two Hydrogel Lenses in Daily Wear
To evaluate the comparative clinical performance of the fanfilcon A silicone hydrogel lens used in daily wear and to compare this with competitive hydrogel lens products.
- Trial name
- NCT04050618
- Testing
- fanfilcon A test lens, ocufilcon D control lens, etafilcon A control lens
- Where
- 6 sites in United States
- Volunteers
- 114 people
- Sponsor
- CooperVision, Inc.
Myopia, Progressive, Children, Only
Eleven Years of Menicon Z Night Contact Lens Wear in Reducing Myopia Progression in Children
To compare axial length growth of white European myopic children wearing Menicon Z Night orthokeratology contact lenses to a control group of distance, single-vision glasses and contact lenses over an 11-year period.
- Trial name
- MCOS11 (NCT04806711)
- Testing
- Menicon Z Night, Control
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia, Progressive, Children, Only
Long-term Efficacy of Orthokeratology Contact Lens Wear in Controlling the Progression of Childhood Myopia
To assess the long-term efficacy of the Menicon Z Night orthokeratology contact lens in controlling the progression of childhood myopia
- Trial name
- MCOS7 (NCT04806698)
- Testing
- Menicon Z Night, Control
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Contact Lens Wear
A Safety and Effectiveness Study of a New Preservative Free Rewetting Drop
The objective of this study is to evaluate the safety and effectiveness of lubricating and rewetting drop (Test) compared to OPTI-FREE® Replenish® Rewetting Drops (Control) when used by habitual contact lens wearers to…
- Trial name
- NCT04175340
- Testing
- BL-300-PFM04, OPTI-FREE
- Where
- 15 sites in United States
- Volunteers
- 369 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Changes in Invitro and ex Vivo Lens Metrology With Daily Wear Contact Lenses
The purpose of this study is to evaluate changes in contact lens geometry after lens wear
- Trial name
- NCT01100411
- Testing
- Air Optix Aqua, Biofinity, Proclear
- Where
- Australia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Myopia
Evaluation of the CooperVision, Inc. Fanfilcon A and Enfilcon A Daily Wear Contact Lenses When Used for Frequent Replacement for up to One (1) Month of Daily Wear
This study is a masked, multi-center, daily wear, monthly replacement, bilateral, randomized, lens blocked (subjects remain in the same lens brand throughout the study) concurrent control study enrolling up to 90 subjects with a…
- Trial name
- NCT02555722
- Testing
- fanfilcon A (test), enfilcon A (control)
- Where
- 6 sites in United States
- Volunteers
- 92 people
- Sponsor
- CooperVision, Inc.
Myopia
Study Intended to Evaluate the Safety and Effectiveness of a Johnson & Johnson Vision Care Inc, (JJVCI) Contact Lens for Use on an Extended-wear Basis for up to 7 Days (6 Nights).
Study in the US intended to evaluate the safety and effectiveness of a Johnson \& Johnson Vision Care Inc, (JJVCI) contact lens for use on an extended-wear basis for up to 7 days (6 nights).
- Trial name
- NCT00241280
- Testing
- etafilcon A, galyfilcon A
- Where
- 25 sites in United States
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Wear
A Safety and Effectiveness Study of a New Contact Lens Cleaning and Disinfecting Solution
The objective of this study is to evaluate the safety and effectiveness of NNR06 Multi-Purpose Solution cleaning and disinfecting solution (Test) compared to COMPLETE Multi-Purpose Solution cleaning and disinfecting solution…
- Trial name
- NCT02701556
- Testing
- Complete MPS, NNR06
- Where
- United States
- Volunteers
- 396 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
An Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
The purpose of this study was to assess and compare the effect of the repeated usage of 2 different care systems (one hydrogen peroxide based cleaning and disinfecting system and one PHMB containing multipurpose system) with…
- Trial name
- ID11-56 (NCT01594294)
- Testing
- AOSEPT® Plus contact lens solution, ReNu MultiPlus® contact lens solution, Etafilcon A contact lenses
- Volunteers
- 100 people
- Sponsor
- Alcon Research