Clinical trials: Contact Lens Wear
Refractive Errors
Clinical Evaluation of a Daily Wear Monthly Replacement Silicone Hydrogel Lens
The purpose of this clinical study is to evaluate the safety and effectiveness of an investigational soft contact lens compared to a commercially available soft contact lens when worn for daily wear and replaced monthly.
- Trial name
- NCT04178720
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 8 sites in United States
- Volunteers
- 119 people
- Sponsor
- Alcon Research
Contact Lens Fit, Myopia
Clinical Performance of a Silicone Hydrogel Lens With Use of FID 114675A
The purpose of this study is to evaluate the clinical performance of a silicone hydrogel contact lens when used with an investigational multi-purpose disinfecting solution (MPDS).
- Trial name
- NCT01240135
- Testing
- FID 114675A multi-purpose disinfecting solution (MPDS), renu fresh Multi-Purpose Solution (MPS), Galyfilcon A contact lenses (Acuvue Advance)
- Volunteers
- 89 people
- Sponsor
- Alcon Research
Myopia
Vistakon Investigational Contact Lenses Worn for Daily Wear
This study compares the performance of an investigational contact lens to a currently marketed lens.
- Trial name
- NCT00717249
- Testing
- galyifilcon A control lens, galyfilcon A with a silver additive
- Where
- 20 sites in United States
- Volunteers
- 529 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
Lubricity Post-Wear - Competitive Lenses Pilot
The purpose of this study is to measure the coefficient of friction of three silicone hydrogel, daily disposable contact lenses after 16 hours of wear.
- Trial name
- NCT02402127
- Testing
- Narafilcon A contact lenses, Stenfilcon A contact lenses, Somofilcon A contact lenses
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Astigmatism
Evaluation of Two Toric Soft Contact Lenses After Two Weeks of Wear
The purpose of this study is to determine the relative performance of a new toric soft contact lens against a toric contact lens currently available in market, specifically with regards to the comfort and vision after two weeks…
- Trial name
- NCT00584220
- Testing
- senofilcon A toric, alphafilcon A toric
- Volunteers
- 96 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Wear
A Safety and Effectiveness Study of a New Contact Lens Cleaning and Disinfecting Solution
The objective of this study is to evaluate the safety and effectiveness of NNR06 Multi-Purpose Solution cleaning and disinfecting solution (Test) compared to COMPLETE Multi-Purpose Solution cleaning and disinfecting solution…
- Trial name
- NCT02701556
- Testing
- Complete MPS, NNR06
- Where
- United States
- Volunteers
- 396 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Refitting Somofilcon A Sphere Contact Lens Wearers Into Fanfilcon A Sphere Lenses for 4-Weeks of Wear
The aim of this subject-masked prospective study is to evaluate the clinical performance of habitual wearers of Clariti Elite sphere lenses after a refit with Avaira Vitality sphere lenses.
- Trial name
- NCT03974802
- Testing
- somofilcon A contact lens, fanfilcon A contact lens
- Where
- Mexico
- Volunteers
- 41 people
- Sponsor
- CooperVision, Inc.
Contact Lens
Evaluation of Wear Experience With Daily Contact Lenses
To evaluate the wear experience of current monthly replacement contact lens wearers after they have been fit into a daily disposable contact lens.
- Trial name
- NCT05096156
- Testing
- Precision1® Daily Disposable Contact Lens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Astigmatism
Clinical Performance of Toric Hydrogel Contact Lenses Following One Week of Daily Wear
The aim of this prospective study is to evaluate the clinical performance of filcon IV1 toric and ocufilcon D toric contact lenses after 1 week of wear in each pair.
- Trial name
- NCT02847169
- Testing
- filcon IV1 toric lens, ocufilcon D toric lens
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
An Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
The purpose of this study was to assess and compare the effect of the repeated usage of 2 different care systems (one hydrogen peroxide based cleaning and disinfecting system and one PHMB containing multipurpose system) with…
- Trial name
- ID11-56 (NCT01594294)
- Testing
- AOSEPT® Plus contact lens solution, ReNu MultiPlus® contact lens solution, Etafilcon A contact lenses
- Volunteers
- 100 people
- Sponsor
- Alcon Research
Ametropia
Endothelial Bleb Response With Toric Lenses
Evaluate the short-term corneal response of oxygen deprivation when using toric contact lenses. The response will be noted by endothelial bleb formation in both open eye and closed eye state.
- Trial name
- NCT00630305
- Testing
- alphafilcon A toric, lotrafilcon B toric, senofilcon A toric
- Where
- Australia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Wear
A Safety and Effectiveness Study of BL-ABT12 Multi-Purpose Solution for Use by Participants With Soft Contact Lenses
This study is to evaluate the safety and effectiveness of ABT12 Multi-Purpose solution (Test) compared to COMPLETE® Multi-Purpose Solution Easy Rub® Formula ("COMPLETE Multi-Purpose Solution") when used by participants who are…
- Trial name
- NCT03897751
- Testing
- ABT12 Multi-Purpose Solution, COMPLETE Multi-Purpose Solution, Sensitive Eyes® Rewetting Drops
- Where
- 17 sites in United States
- Volunteers
- 252 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Errors
Clinical Performance of a Silicone Hydrogel Contact Lens Following Six Nights of Extended Wear
The purpose of this clinical study is to evaluate the on-eye performance of an investigational soft contact lens compared to a commercially available soft contact lens following 1 week of extended wear.
- Trial name
- NCT03614130
- Testing
- LID011121 contact lens, Comfilcon A contact lens
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Alcon Research
Scleral Lens Wearers
Efficacy of Scleral Contact Lenses for Daily Wear for Regular and Irregular Refractive Errors Compared to Habitually Worn Scleral Lenses
This study will be done with subjects who already habitually wear scleral contact lenses. The study lens is made with a material that is already widely available and has a new design.
- Trial name
- NCT02643095
- Testing
- scleral contact lens
- Volunteers
- 22 people
- Sponsor
- Jennifer Fogt
Refractive Errors
Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations
The purpose of this study is to evaluate corneal staining observed after 2 hours of wear with an investigational contact lens against both PureVision contact lenses pre-cycled with Biotrue and Biofinity contact lenses pre-cycled…
- Trial name
- NCT04789382
- Testing
- LID018869+RepleniSH, LID018869+Biotrue, Biofinity+RepleniSH
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Astigmatism
Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear
This is a prospective, multi-site, 4-visit, bilateral, dispensing, randomized, controlled, double-masked, 2x2 crossover study to evaluate subjective comfort, overall opinion and end of day comfort following wear of two different…
- Trial name
- NCT06749496
- Testing
- Test Lens, Control Lens
- Where
- 12 sites in United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors
Safety and Effectiveness of the Qualis Contact Lens
Three-month, open-label, bilateral, parallel group, randomized, daily wear contact lens dispensing study.
- Trial name
- NCT04295499
- Testing
- soft (hydrophilic) contact lens
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Unicon Optical Co. Ltd.
Contact Lens Wear
Vistakon Investigational Multi-purpose Contact Lens Care Solution.
This study compares an investigational contact lens care multi-purpose solution to a currently marketed multi-purpose solution.
- Trial name
- NCT01055457
- Testing
- Vistakon Investigational Multi-Purpose Solution II, ReNu MultiPlus Multi-Purpose Solution
- Where
- 14 sites in United States
- Volunteers
- 315 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors, Astigmatism
Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens
The purpose of this clinical study is to assess the clinical performance of an investigational toric soft contact lens compared to a commercially available toric contact lens in a crossover dispense trial when worn in a daily…
- Trial name
- NCT05211739
- Testing
- Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
- Where
- 7 sites in United States
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Astigmatism Bilateral
Evaluation of Wear Experience With Daily Disposable and Monthly Replacement Toric Contact Lenses
Comparison of wear experience with daily disposable and monthly replacement soft contact lenses in contact lens wearers who have astigmatism.
- Trial name
- NCT05580575
- Testing
- Daily disposable toric soft contact lens, Monthly replacement toric daily wear soft contact lens
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Ohio State University