Clinical trials: Contact Lenses
Corneal Staining
Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
An investigational multi-purpose solution (MPS)was clinically evaluated against Biotrue MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Trial name
- NCT01240122
- Testing
- Biotrue MPS, Investigational MPS
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Keratoconus
Twelve Month Clinical Evaluation of KeraSoft IC Soft Contact Lenses
The objective of this twelve month dispensing study is to evaluate the clinical performance, particularly comfort and vision, of KeraSoft IC Soft Contact Lenses.
- Trial name
- NCT01416272
- Testing
- KeraSoft IC Soft Contact Lenses
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error
Evaluation of a Johnson & Johnson Vision Care Investigational Contact Lens Compared to a Marketed Monthly Replacement Contact Lens
Randomized, double-masked, controlled, 2-arm parallel group, multi-site, 3-month dispensing study of Johnson \& Johnson Vision Care, Inc.
- Trial name
- NCT02515994
- Testing
- senofilcon C, comfilcon A
- Where
- 10 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia, Myopia
Comparison of Two Multifocal Contact Lenses Worn on a Daily Disposable Basis
The purpose of this trial is to evaluate and compare the clinical performance of two multifocal contact lenses.
- Trial name
- NCT01254760
- Testing
- Nelfilcon A multifocal contact lens, investigational, Nelfilcon A multifocal contact lens, commercial
- Volunteers
- 79 people
- Sponsor
- CIBA VISION
Visual Acuity
Evaluation of Toric Soft Contact Lenses Containing a Chromophore to Block High-Energy Visible Light
This will be a 4-visit, randomized, controlled, single-masked, bilateral wear, dispensing, 2-treament, 2-sequence, 3-period crossover study to evalulate overall vision and comfort..
- Trial name
- NCT05344560
- Testing
- soft contact lens in senofilcon A (C3) with HEVL-blocking chromophore, ACUVUE OASYS 1-Day for Astigmatism
- Where
- 10 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
DAILIES TOTAL1® - Comparative Assessment of Tear Film Evaporation
The purpose of this study is to evaluate the tear film evaporation of symptomatic soft contact lens wearers in the absence of contact lens wear and after at least 8 hours of contact lens wear.
- Trial name
- NCT02517567
- Testing
- Delefilcon A contact lenses, Narafilcon A contact lenses, Somofilcon A contact lenses
- Volunteers
- 37 people
- Sponsor
- Alcon Research
Ametropia
Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Roflufocon D
This will be an up to six months, subject-masked, contralateral, parallel-group, randomised, daily wear study. All subjects will wear the Test lens in one eye and the Control lens in the other eye.
- Trial name
- NCT02553681
- Testing
- roflufocon D contact lenses, RGP contact lenses made from roflufocon D
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Myopia
Feasibility of a New Silicone Hydrogel Lens
The objective of this study is to determine the product feasibility of the investigational contact lens (Test) when compared to the currently marketed Acuvue Oasys contact lens (Control) and the Air Optix Aqua contact lens…
- Trial name
- NCT01131130
- Testing
- Investigational contact lens, Acuvue Oasys Contact Lens, Air Optix Aqua
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Bausch & Lomb Incorporated
Ametropia
Evaluation of Monthly Replacement Lenses in Habitual Soft Contact Lens Wearers Who Report Frequent Digital Devise Use
To evaluate the clinical performance of two monthly silicone hydrogel contact lenses in habitual wearers of frequent replacement (FRP) lenses when worn for 1-month.
- Trial name
- NCT05166902
- Testing
- Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
- Where
- 4 sites in United States, Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Visual Acuity
Evaluation of Electronic LogMar Visual Acuity and Contrast Sensitivity in a Population of Contact Lens Wearers
This is a bilateral, non-dispensing, randomized, cross-over, single-masked study. There are a total of 3 visits where all study endpoints will be measured in all subjects at baseline with habitual lenses and under the two testing…
- Trial name
- NCT03222037
- Testing
- senofilcon A, Control
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Clinical Performance Comparison of Several Different Contact Lenses
The purpose of the study is to evaluate the possible benefits of second generation silicone hydrogel contact lenses.
- Trial name
- NCT00912028
- Testing
- senofilcon A, lotrafilcon B, balafilcon A
- Where
- 11 sites in Brazil
- Volunteers
- 71 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Daily Disposable Silicone Hydrogel Contact Lens, Stenfilcon A, Clinical Study
Clinical evaluation of stenfilcon A compared with narafilcon A and delefilcon A This is a total 120 subject, randomized, open label, bilateral wear, two week crossover study (each lens for 1 week) evaluating the clinical…
- Trial name
- NCT02637804
- Testing
- stenfilcon A, narafilcon A, delefilcon A
- Volunteers
- 106 people
- Sponsor
- CooperVision, Inc.
Myopia, Refractive Errors
A Clinical Trial to Evaluate the Vision Correction Safety and Efficacy of MSiHy Silicone Hydrogel Soft Contact Lens
This is a prospective, randomized, double-blind, parallel, active-controlled, multi-center clinical study. The purpose is to evaluate the safety and effectiveness wearing "MSiHy Silicone Hydrogel Soft Contact Lens".
- Trial name
- NCT06716385
- Testing
- MSiHy Silicone Hydrogel Soft Contact Lens, Monthly Silicone Hydrogel Contact Lenses (oA)
- Where
- 3 sites in Taiwan
- Volunteers
- 134 people
- Sponsor
- Visco Vision Inc.
Myopia
A Study to Assess the Safety and Efficacy of a Daily Disposable Contact Lens
The objective of this study is to evaluate the safety and efficacy of the Bausch \& Lomb daily disposable tint contact lens (Test) compared to a currently marketed daily disposable cosmetic tint contact lens (Control).
- Trial name
- NCT01130974
- Testing
- Bausch & Lomb contact lens, Marketed daily disposable contact lens
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error
Evaluation of Vision Effects of a Cosmetic Tinted Hydrogel Contact Lens
Subjects will wear 2 of 2 study contact lenses for a wearing time of approximately three to four hours at each of the visits in order to take measurements on binocular functional visual performance.
- Trial name
- NCT02886923
- Testing
- Hioxifilcon A Test, Hioxifilcon A With Cosmetic Ring Control
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Investigational Contact Lenses
Single-visit, unmasked, non-dispensing study where subjects will wear three different lenses bilaterally in one visit, each lens being worn for approximately 30-60 minutes.
- Trial name
- NCT02801396
- Testing
- Etafilcon A Design 1 (Test 1), Etafilcon A Design 2 (Test 2), Etafilcon A (Control)
- Where
- Hong Kong
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cosmetic Appearance
Lotrafilcon B Plano Cosmetic Contact Lenses Study
The purpose of this study is to gather long-term performance and safety data on AIR OPTIX™ COLORS (lotrafilcon B) plano cosmetic contact lenses in subjects 12 years of age and older.
- Trial name
- NCT06493383
- Testing
- Lotrafilcon B plano cosmetic contact lenses
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Care
Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
The purpose of this study was to assess and compare the effect of the repeated usage of two different contact lens care systems (one hydrogen peroxide-based cleaning and disinfecting system, and one polyaminopropyl biguanide…
- Trial name
- NCT01494818
- Testing
- Hydrogen peroxide-based contact lens care system, PHMB-containing contact lens solution, Soft contact lenses
- Volunteers
- 79 people
- Sponsor
- Alcon Research
Refractive Error, Myopia
A Comparative Study of Two Daily Disposable Contact Lenses in Higher Myopia Subjects
The purpose of this study is to compare the change from baseline in central corneal curvature at one week, between 2 silicone hydrogel lenses, in higher myopic subjects.
- Trial name
- NCT02066922
- Testing
- Delefilcon A contact lens, Narafilcon A contact lens, Spectacles
- Volunteers
- 19 people
- Sponsor
- Alcon Research
Visual Acuity
Evaluation of Approved Contact Lenses
This is a prospective, randomized, controlled, subject-masked, bilateral, dispensing, multi-site, 2 lenses × 3 wearing periods crossover study to evaluate visual acuity.
- Trial name
- NCT07174596
- Testing
- B+L Infuse spherical soft contact lenses, J&J ACUVUE OASYS 1-Day spherical soft contact lenses
- Where
- 4 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.