Clinical trials: Continuous Positive Airway Pressure
Sleep Apnea Syndromes
Race And CPAP Effectiveness
Obstructive sleep apnea (OSA) is a major public health problem in the U.S. and more than 35% of Veterans are at high risk for OSA. OSA is associated with progression of hypertension, an important health problem in Veterans.
- Trial name
- RACE (NCT01960465)
- Testing
- Continuous positive airway pressure
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea, Obstructive
Study to Predict the Need for Humidification Use and Comparison of the Effect of ThermoSmart™ and no Humidification on Adherence
Despite the effectiveness of continuous positive airway pressure (CPAP) in abolishing upper airway obstruction, acceptance of and adherence with therapy has been sub-optimal.
- Trial name
- NCT01517750
- Testing
- ICON Auto CPAP™ with Thermosmart heated tube, ICON Auto CPAP™ without Thermosmart heated tube
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Fisher and Paykel Healthcare
Sleep Disordered Breathing
Continuous Positive Airway Pressure and Cardiometabolic Risk
The hypothesis for this study is that children with sleep disordered breathing will benefit from treatment with Continuous Positive Airway Pressure (CPAP) or Bi-level Positive Airway Pressure (BiPAP) in terms of reduction in…
- Trial name
- NCT01403194
- Testing
- CPAP/BiPAP
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Mayo Clinic
Obstructive Sleep Apnea, Type 2 Diabetes
Effects of Continuous Positive Airway Pressure (CPAP) Treatment on Glucose Control in Patients With Type 2 Diabetes
The overall goal of the proposed protocol is to rigorously test the hypothesis that CPAP treatment has beneficial effects on glycemic control in patients with both type 2 diabetes (T2DM) and obstructive sleep apnea (OSA).
- Trial name
- CPAP (NCT01136785)
- Testing
- active CPAP Therapy
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Chicago
Obstructive Sleep Apnea
Improving the Frequency and Quality of Sleep Apnea Care Management
OSA is a major chronic condition affecting the quality of life of millions of Americans. Per the Institute of Medicine new treatment adherence strategies are needed to help improve the quality of care, reduce social and economic…
- Trial name
- NCT01916655
- Testing
- Self-Management Care, Self-Management Mobile Care, Usual Care
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea Syndromes, Oxidative Stress
Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea
Sleep-disordered breathing (SDB) is a condition in which a person experiences frequent breathing pauses during sleep, also known as sleep apnea.
- Conditions
- Sleep Apnea Syndromes, Oxidative Stress, Cardiovascular Diseases
- Trial name
- SASS (NCT00607893)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
COVID-19, COVID
Early CPAP in COVID-19 Confirmed or Suspected Patients
There is surge in COVID infected patients in New York City with a shortage of hospital beds, ICU beds and ventilators. Strategies to reduce the need for all of the above are immediately needed.
- Conditions
- COVID-19, COVID, Coronavirus
- Trial name
- PAP-COVID (NCT04390191)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Apnea, Sleep, Chronic Fatigue Syndrome
Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
The purpose of this study is to determine any sleep disordered breathing in veterans with Gulf War Syndrome (GWS) and compare it to healthy normal asymptomatic Gulf War veterans.
- Trial name
- NCT00252629
- Testing
- Nasal CPAP treatment during sleep
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- US Department of Veterans Affairs
Sleep Apnea, Obstructive
Group-based Peer Support Versus Individual Education for Patients Undergoing CPAP Treatment
The investigators will compare two alternatives designed to maximize adherence to continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) - peer-support administered in groups, versus individual…
- Trial name
- NCT02538419
- Testing
- CPAP + Peer Support, CPAP + Individual Education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea, Obstructive
Auto Continuous Positive Airway Pressure (CPAP) Based Energy Spectrum Analysis of Flow for Treatment of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Nasal Continuous Positive Airway Pressure (CPAP) is the standard therapy for obstructive sleep apnea hypopnea syndrome (OSAHS). This is most commonly administered as a single positive pressure that has been individualized for the…
- Trial name
- NCT00750165
- Testing
- SleepStyle 200 Auto Series CPAP Humidifier
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Fisher and Paykel Healthcare
Epilepsy, Sleep Apnea
Effects of Treating Obstructive Sleep Apnea in Epilepsy
The purpose of this trial is to work out design issues prior to conducting a definitive phase 3 trial to determine whether treating sleep-related breathing disorders in people with epilepsy results in improvement in seizure…
- Conditions
- Epilepsy, Sleep Apnea, Obstructive Sleep Apnea
- Trial name
- NCT00047463
- Testing
- continuous positive airway pressure (CPAP)
- Where
- 4 sites in United States
- Volunteers
- 68 people
- Sponsor
- Vanderbilt University
Sleep Apnea, Sleep Disordered Breathing
Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea
Patients with Obstructive Sleep Apnea Syndrome (OSAS) will evidence higher levels of salivary cortisol and alpha-amylase levels prior to use of placebo and continuous positive airway pressure (CPAP) and will evidence a decrease…
- Trial name
- NCT01196117
- Testing
- 14 days of CPAP therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Medical College of Wisconsin
Oropharyngeal Dysphagia, Laryngectomy; Status
CPAP to Improve Swallow Function Post Total Laryngectomy
Investigator initiated prospective study to determine whether use of Continuous Positive Airway Pressure (CPAP) can improve the swallow function in patients who underwent total laryngectomy and are experiencing difficulty…
- Trial name
- NCT03328702
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, Davis
Obstructive Sleep Apnea
Effects of CPAP on Visceral Fat Thickness
We hypothesize that patients with untreated OSAS will have more visceral fat, fatty liver and increased carotid artery thickness whereas treatment with CPAP may reduce the mesenteric and liver fat, plasma lipids, carotid artery…
- Trial name
- NCT01828281
- Testing
- CPAP
- Where
- China
- Volunteers
- 141 people
- Sponsor
- Chinese University of Hong Kong
Adherence
CPAP (Continuous Positive Airway Pressure) Study Educational Materials and Usage Feedback to Promote CPAP Adherence
The study hypothesis: in groups receiving tailored education and feedback in a style that matches their psychological profile, will show a higher CPAP adherence rates than groups receiving mismatched tailored education /…
- Trial name
- NCT02195531
- Testing
- Education and feedback
- Where
- 6 sites in United States
- Volunteers
- 169 people
- Sponsor
- Philips Respironics
Transient Tachypnea of the Newborn
High Flow Nasal Cannula Versus Bubble Nasal CPAP for the Treatment of Transient Tachypnea of the Newborn in Infants ≥ 35 Weeks Gestation
The primary objective is to determine whether High Flow Nasal Cannula (HFNC) is a superior respiratory modality for neonates ≥36 weeks with transient tachypnea of the newborn (TTN) when compared to the standard of care modality…
- Trial name
- NCT01270581
- Testing
- High Flow Nasal Cannula, Bubble Nasal CPAP
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obstructive Sleep Apnea
Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy
Prospective, randomized controlled trial. Pregnant women in early pregnancy will be randomized to either the Sleep Study + CPAP (Continuous Positive Airway Pressure Therapy) group or to a Standard Prenatal Care group.
- Trial name
- NCT02755831
- Testing
- CPAP, Pre-natal care
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Respiratory Distress Syndrome, Newborn
Delivery Room Management Trial of Premature Infants at High Risk of Respiratory Distress Syndrome
The best mode of delivery room stabilization for premature infants at high risk for respiratory distress syndrome is unknown. The protocol evaluates the impact of three distinct methods of post-delivery stabilization and…
- Trial name
- NCT00244101
- Testing
- PS Group, NCPAP Group, ISX Group
- Where
- United States
- Volunteers
- 648 people
- Sponsor
- Vermont Oxford Network
Lung Diseases, Sleep Apnea Syndromes
Continuous Positive Airway Pressure to Improve Milder Obstructive Sleep Apnea
The purpose of this study is to determine whether functional status improves in individuals with milder obstructive sleep apnea (OSA) following continuous positive airway pressure (CPAP) treatment.
- Conditions
- Lung Diseases, Sleep Apnea Syndromes, Hypertension
- Trial name
- CATNAP (NCT00089752)
- Testing
- Continuous Positive Airway Pressure (CPAP) Treatment
- Where
- 5 sites in United States, Canada
- Volunteers
- 281 people
- Sponsor
- University of Pennsylvania
Sleep Apnea, Obstructive, Brain Injuries, Traumatic
Feasibility of Improving Sleep Apnea Treatment Adherence After Brain Injury
Background: Obstructive sleep apnea (OSA) is a sleep disorder common among Veterans with moderate-to-severe traumatic brain injury (TBI).
- Trial name
- FISATABI (NCT04221009)
- Testing
- MI and CBT 4-session manualized intervention
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development