Clinical trials: Continuous Positive Airway Pressure (CPAP)
Obesity, Abdominal, Anesthesia Morbidity
CPAP in Patients With Severe Obesity After Anesthesia
The goal of this study is to compare two continuous positive airway pressure (CPAP) settings on heart and lung function in patients with severe obesity after anesthesia. The main questions it aims to answer are: 1.
- Conditions
- Obesity, Abdominal, Anesthesia Morbidity, Apnea, Obstructive Sleep, Atelectases, Postoperative Pulmonary
- Trial name
- NCT06287632
- Testing
- Recruitment/ITP-CPAP (Intervention A), Standard CPAP (Intervention B), Atmospheric Pressure
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Obstructive Sleep Apnea, Atherosclerosis
Early Signs of Atherosclerosis in Obstructive Sleep Apnea: Effects of Treatment
Obstructive sleep apnea (OSA) is associated with adverse cardiovascular outcomes, including acute myocardial infarction and stroke. Atherosclerosis is an important step for these events.
- Trial name
- NCT00400543
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo
Chronic Pain, Obstructive Sleep Apnea
Clinical Outcomes of Continuous Positive Airway Pressure Treatment in People With Obstructive Sleep Apnea and Chronic Pain
The bidirectional link between sleep and pain is a widely accepted concept. While there has been much focus on this in recent years, studies investigating obstructive sleep apnoea (OSA) and chronic pain are still not very common…
- Trial name
- NCT06834724
- Testing
- Standard OSA care
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Vrije Universiteit Brussel
Preterm Neonates
Trial of Weaning of Nasal Continuous Positive Airway Pressure (CPAP)
To compare the 2 methods of weaning of nasal CPAP in premature babies born at 32 weeks or less
- Trial name
- NCT01215591
- Testing
- Gradual weaning from Nasal CPAP in preterm neonates
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Maimonides Medical Center
COVID-19
Comparison of 2 Ventilatory Support Strategies During Coronavirus Disease 2019 (Covid-19) Pneumonia
This retrospective monocentric study compares 2 ventilatory support strategies on outcomes (length of stay, intubation, mortality) in patients admitted in Intensive Care Unit with Covid-19 related pneumonia : invasive strategy…
- Trial name
- STRATIC (NCT04799691)
- Testing
- Invasive ventilation strategy, Non-invasive ventilation strategies
- Where
- France
- Volunteers
- 133 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Heart Failure, Obstructive Sleep Apnea
ASV Effects on Myocardial Energetics and Sympathetic Nerve Function in Heart Failure and Sleep Apnea.
Obstructive sleep apnea (OSA), central sleep apnea (CSA) and heart failure (HF) are states of metabolic demand and sympathetic nervous system (SNS) activation.
- Conditions
- Heart Failure, Obstructive Sleep Apnea, Central Sleep Apnea
- Trial name
- AMEND (NCT02116140)
- Testing
- [C11]Acetate and HED PET
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Pneumonia, Pleural Effusion
Physiotherapy Technique Decreases Respiratory Complications After Cardiac Operation
The objective of this study is to assess whether there is a difference between a care protocol with the use of incentive spirometry (Voldyne ®) and another with the application of NIV (non invasive ventilation with single-level…
- Conditions
- Pneumonia, Pleural Effusion, Atelectasis
- Trial name
- NCT01416519
- Testing
- Continuous Positive Airway Pressure (CPAP) facial mask, Assisted deep inspiration technique
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Santa Casa de Votuporanga
Sarcoidosis, Sleep Apnea, Obstructive
Prevalence of Obstructive Sleep Apnea Syndrome in Sarcoidosis and Impact of CPAP Treatment on Associated Fatigue Status
Sarcoidosis is a multisystemic granulomatous disease that affects individuals worldwide without known pathogenesis, and the role of comorbidities has not been fully assessed in the scientific literature.
- Conditions
- Sarcoidosis, Sleep Apnea, Obstructive, Fatigue
- Trial name
- SARCOIDOSAS (NCT03926832)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Post Traumatic Stress Disorder, Anxiety
The Effect of Nasal Continuous Positive Airway Pressure Treatment on PTSD Symptoms.
We hypothesize that prevention of Sleep Disordered Breathing among PTSD patients with nasal CPAP will result improve their anxiety, insomnia and alcohol craving (among those who use alcohol to control their symptoms).
- Conditions
- Post Traumatic Stress Disorder, Anxiety, Nightmares, Unrefreshed Sleep
- Trial name
- PTSD (NCT01512771)
- Testing
- CPAP
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northport Veterans Affairs Medical Center
Sleep Apnea, Obstructive, Endothelial Dysfunction
Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal
Obstructive sleep apnea hypopnea syndrome (OSAS) is a frequent disease with neuropsychological and cardiovascular (CV) consequences.
- Trial name
- ORTAP (NCT05939934)
- Testing
- Mandibular advancement device treatment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Sleep Apnea, Obstructive, Stroke
Stroke and CPAP Outcome Study 2
Obstructive sleep apnea (OSA) is associated with impaired stroke recovery. Treatment with continuous positive airway pressure (CPAP) may prevent this but is limited by poor adherence.
- Conditions
- Sleep Apnea, Obstructive, Stroke, Patient Adherence
- Trial name
- SCOUTS2 (NCT02809430)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Washington
Sleep Apnea, Heart Failure
Cardiac Function After CPAP Therapy in Patients With Chronic Heart Failure and Sleep Apnea. A Multicenter Study
The role of continuous positive airway pressure (CPAP) in cardiac function in patients with CSA and OSA has been studied with varying results.
- Conditions
- Sleep Apnea, Heart Failure, Cardiovascular Diseases
- Trial name
- NCT00404807
- Testing
- CPAP(Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 245 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
COVID, Acute Hypoxemic Respiratory Failure
Helmet CPAP Versus HFNC in COVID-19
We aim to investigate whether the use of Continuous Positive Airway Pressure using a Helmet device (Helmet CPAP) will increase the number of days alive and free of ventilator within 28 days compared to the use of a High Flow…
- Trial name
- COVID HELMET (NCT04395807)
- Testing
- Helmet CPAP, HFNC
- Where
- Sweden
- Volunteers
- 2 people
- Sponsor
- Lund University
Respiratory Distress of Newborn
Comparison of Continuous Positive Airway Pressure and Non Invasive Positive Pressure Ventilation
The objective of the study is to compare the effectiveness of treatment with Non Invasive Positive Pressure Ventilation (NIPPV) and continuous positive airway pressure (CPAP) in decreasing the requirement for endotracheal…
- Trial name
- NCT03347136
- Testing
- CPAP, NIPPV
- Where
- Sri Lanka
- Volunteers
- 80 people
- Sponsor
- Ministry of Health, Sri Lanka
Acute Respiratory Failure
High Flow Nasal Cannulas in Children
Non-invasive Continuous Positive Airway Pressure (nCPAP) is widely recognized as an efficient respiratory support in infants with mild to moderate Acute Hypoxemic Respiratory Failure (AHRF).
- Trial name
- HFNC (NCT03689686)
- Testing
- Noninvasive Respiratory Support
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Obstructive Sleep Apnea
Effects of Humidity (During CPAP Treatment) on Mucociliary Clearance in Patients With Obstructive Sleep Apnea
That the level of humidification delivered to patients during CPAP treatment will alter the subjects mucociliary clearance rate and related mucus properties.
- Trial name
- CIA-6 (NCT00790166)
- Testing
- CPAP + ThermoSmart™ humidity, CPAP + Conventional humidity, CPAP + No added humidity
- Where
- Brazil
- Volunteers
- 4 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Revised Algorithm for Next Generation DeVilbiss Healthcare AutoAdjust Continuous Positive Airway Pressure (CPAP)
The purpose of this protocol is to improve the current FDA-approved continuous positive pressure auto-titration algorithm, including treatment precision, residual disease detection characteristics and phenotyping with the…
- Trial name
- NCT01797705
- Testing
- DeVilbiss AutoAdjust CPAP with revised algorithm
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- DeVilbiss Healthcare LLC
Quality of Life, Sleep Apnea Syndromes
Compare Outcomes of SMG and CPAP in OSA
The objectives of this study is to compare short-term outcomes of CPAP and Adjustable thermoplastic oral appliance in the treatment of obstructive sleep apnea.
- Trial name
- NCT02766179
- Testing
- CPAP, Somnoguard
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Carcinoma Liver, Carcinoma, Pancreatic
MRI Only Radiation Therapy With CPAP
The goal of this imaging study is to evaluate and improve the treatment planning techniques for abdominal radiation therapy. To accurately treat a tumor with radiation, Computed Tomography (CT) and Magnetic Resonance Images (MRI)…
- Trial name
- NCT03397342
- Testing
- CPAP machine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Albert Einstein College of Medicine
Obstructive Sleep Apnea
Transcutaneous Electrical Stimulation in Patients With Obstructive Sleep Apnoea
The objective of this trial is to assess efficacy and compliance of transcutaneous electrical stimulation of the upper airway dilator muscles in patients with obstructive sleep apnoea (TESLA) who do not tolerate continuous…
- Trial name
- TESLA-MICRON (NCT07343362)
- Testing
- ZeusOSA, CPAP
- Volunteers
- 186 people
- Sponsor
- Zeus Sleep Ltd