Clinical trials: Continuous Spinal Anesthesia
Octagenerian Population Undergoing Hip Surgeries
Effects of Continuous Versus Single Dose Spinal Anesthesia in Octagenerians Undergoing Hip Surgery
Continuous spinal anesthesia (CSA) is an anesthetic technique that offers several clinical advantages for anesthesia and analgesia in elderly patients.
- Trial name
- NCT05418374
- Testing
- Continous Spinal Anestheisa
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypotension Symptomatic, Obstetric Anesthesia Problems
Prevention of Hypotension During Cesarean Section
The aim of this double-blind randomized study will be to compare a fixed-rate prophylactic noradrenaline infusion to a fixed-rate prophylactic phenylephrine infusion during elective cesarean section under combined spinal-epidural…
- Conditions
- Hypotension Symptomatic, Obstetric Anesthesia Problems, Cesarean Section Complications, Vasoconstriction
- Trial name
- NOR-PHEN (NCT03842046)
- Testing
- phenylephrine infusion, norepinephrine infusion
- Where
- 2 sites in Greece
- Volunteers
- 82 people
- Sponsor
- Aretaieion University Hospital
Spinal Anesthesia
Ultrasound Guided Midline vs Landmark Paramedian Continous Spinal Anesthesia in the Elderly
Former clinical studies have reported the superiority of the landmark guided paramedian approach above the classical landmark guided midline approach for the continuous spinal anesthesia especially in the elderly.
- Trial name
- NCT06740994
- Testing
- conventional landmark paramedian technique, preprocedural ultrasound guided midline technique
- Where
- Tunisia
- Volunteers
- 110 people
- Sponsor
- University Tunis El Manar
Cesarean Section Complications, Spinal Anesthesia
Norepinephrine Versus Phenylephrine Continuous Variable Infusion in Cesarean Delivery
Comparison will be conducted between continuous variable infusions of Phenylephrine with starting dose of 0.75 mcg/Kg/min and Norepinephrine Bitartrate with starting dose of 0.1 mcg/Kg/min (with norepinephrine base of 0.05…
- Trial name
- NCT03328533
- Testing
- Phenylephrine, Norepinephrine, Bupivacaine
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Cairo University
Cesarean Section Complications, Spinal Anesthesia
Phenylephrine Versus Norepinephrine for Maintenance of Hemodynamic During Cesarean Section Under Spinal Anesthesia
Comparison between prophylactic continuous variable infusion of phenylephrine (starting dose 0,5mcg/kg/min) and norepinephrine tartrate (starting dose 0,1mcg/kg/min) to prevent hypotension and maintain cardiac output under spinal…
- Trial name
- PHENAD (NCT03849508)
- Testing
- Norepinephrine, Phenylephrine
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Maternal Hypotension After Spinal Anesthesia
Comparison of Prophylactic Continuous Infusion of Norepinephrine, Ephedrine, and Their Combination for Prevention of Hypotension During Spinal Anaesthesia for Caesarean Delivery
Background Spinal anaesthesia is the preferred anaesthetic technique for most elective Caesarean deliveries; however, maternal hypotension following spinal anaesthesia remains very common and may be associated with maternal…
- Trial name
- NCT07899216
- Testing
- continuous infusion of noreadrenaline at a fixed rate of 30 ml/min of 4ug/ml, continious ephedrine infusion at a rate of 30 ml/min, Patients will receive a combined infusion of norepinephrine 2 µg/min and ephedrine 2 mg/min.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Hypotension After Spinal Anesthesia, Hypotension During Cesarean Delivery
Comparison of the Efficacy of Continuous Metaraminol Infusion Versus Continuous Norepinephrine Infusion for the Prevention of Hypotension During Cesarean Section Under Spinal Anaesthesia. A Randomised Controlled Trial.
The aim of this double-blind randomised study will be to compare a fixed-rate prophylactic metaraminol infusion to a fixed-rate prophylactic norepinephrine infusion during elective cesarean section under combined spinal-epidural…
- Trial name
- NCT07363109
- Testing
- Metaraminol infusion, Norepinephrine infusion
- Volunteers
- 80 people
- Sponsor
- Aretaieion University Hospital
Analgesia, Patient-Controlled, Epidural Analgesia
Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.
The purpose of this study is to determine which postoperative analgesia is optimal after colorectal surgery. The investigators will compare intrathecal morphine, continuous epidural analgesia and standard systemic analgesia.
- Conditions
- Analgesia, Patient-Controlled, Epidural Analgesia, Anesthesia; Spinal, Morphine
- Trial name
- KOLORIT (NCT03007121)
- Testing
- Morphine intrathecal, Bupivacaine + Sufentanil epidural, Morphine intravenous
- Where
- Czechia
- Volunteers
- 75 people
- Sponsor
- Charles University, Czech Republic
Hemodynamic Instability
Hemodynamic Effects of Continuous Spinal Anesthesia in Patient Aged Over 65 Years
Compared to single-dose spinal anesthesia, continuous spinal anesthesia using small titrated doses of local anesthetic, was safe, efficient and provided better hemodynamic profile in elderly patients.
- Trial name
- NCT03195166
- Testing
- FloTrac sensor/Vigileo
- Where
- Tunisia
- Volunteers
- 20 people
- Sponsor
- University Tunis El Manar
Postoperative Pain
Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section
The cesarean section is considered as a painful surgery during the post operative period. Mothers may need to move immediately after the surgery to take care of their babies.
- Trial name
- NCT02279628
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Epidural Catheter
Continuous Spinal Anesthesia Versus Epidural Anesthesia in Geriatric
60 patients aged older than 60 years, American Society of Anesthesiologists (ASA) class II or III and scheduled for major hip surgery will be randomized, in to two groups anesthetized using continuous spinal anesthesia or using…
- Trial name
- NCT06340256
- Testing
- Continuous spinal anesthesia, Continuous epidural anesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hip Fracture, Hypotension
Continuous Spinal Anesthesia With Hypobaric Bupivacaine to Preserve Hemodynamics in Elderly
The study evaluates the potential beneficial effects on hemodynamics when hypobaric bupivacaine is used instead of isobaric bupivacaine in continuous spinal anesthesia for surgical repair of hip fracture in elderly patients.
- Trial name
- NCT02428257
- Testing
- continuous spinal anesthesia, hypobaric bupivacaine, isobaric bupivacaine
- Where
- Tunisia
- Volunteers
- 120 people
- Sponsor
- Institut Kassab d'Orthopédie
Supine Hypotensive Syndrome
Hemodynamic Management in Women With SHS
Supine hypotensive syndrome often occurs following spinal anesthesia for cesarean delivery.In our study we base the regulation and drug administration both on the regular monitor and on a novel monitor which reflects upon the…
- Trial name
- NCT05341362
- Testing
- LiDCOrapid
- Where
- China
- Volunteers
- 60 people
- Sponsor
- China Medical University, China
Shivering Caused by Spinal Anesthesia
Effect of Continuous Phenylephrine Infusion on Preventing Shivering After Spinal Anesthesia in Cesarean Section
This study aims to evaluate the effectiveness of continuous phenylephrine infusion at 50 mcg/min in preventing shivering after spinal anesthesia in cesarean section.
- Trial name
- NCT07663149
- Testing
- Phenylephrine
- Where
- Indonesia
- Volunteers
- 108 people
- Sponsor
- Universitas Indonesia
Pregnant Women
Estimation of the Effective Dose (ED) 95 of Intrathecal Hyperbaric Prilocaine 2% for Scheduled Cesarean Delivery.
Prilocaine is a local anesthetic drug which as an intermediate duration of action shorter than bupivacaine 0,5% that is usually used for spinal anesthesia in scheduled cesarean section.
- Trial name
- NCT03607916
- Testing
- Hyperbaric prilocaine 2%, Morphine
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Hypotension
The Effect of Intravenous Prehydration on the Hemodynamic Status of Healthy Parturients Undergoing Spinal Anesthesia for Cesarean Delivery
Regional anesthesia (spinal, epidural) is considered the method of choice for anesthesia obstetric deliveries because of the ability to use fewer drugs, a more direct experience of childbirth and the capability to provide…
- Trial name
- NCT01835873
- Testing
- Lactated Ringer's, HES 130/0.42
- Where
- Greece
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Total Hip Replacement
Hemodynamic Effect of Lumbosacral Plexus Blockade Versus Spinal Anesthesia
The study evaluates the hemodynamic effect of lumbosacral plexus blockades versus spinal anesthesia for hip replacement. Half of participants will receive lumbosacral plexus blockade and the other half will receive continuous…
- Trial name
- NCT02544269
- Testing
- Ropivacaine, Bupivacaine
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- University of Aarhus
Spinal Anesthesia, Hemodynamic Changes
Hemodynamic Effects of Bilateral and Unilateral Spinal Anesthesia Using the Continuous Pressure Recording Analytical Method.
This randomized controlled study aims to compare the intraoperative hemodynamic effects of unilateral and bilateral spinal anesthesia in elderly patients undergoing elective total hip arthroplasty.
- Trial name
- NCT07789795
- Testing
- Unilateral Spinal Anesthesia, Bilateral Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Kayseri City Hospital
Coxarthrosis, Pain, Postoperative
Lumbar ESPB in Hip Replacement Surgery
In this study, continuous erector spinae plane block (ESPB) will be compared to continuous epidural analgesia in patients undergoing elective hip replacement surgery.
- Conditions
- Coxarthrosis, Pain, Postoperative, Pain, Acute, Pain, Chronic
- Trial name
- ESPB_HIP (NCT06282666)
- Testing
- Spinal anesthesia, lumbar erector spinae plane block, Epidural analgesia
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lublin
Spinal Fusion Acquired, Spinal Stenosis
Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion
Major lumbar spine surgery causes inflammation, soreness and swelling that can delay discharge from the hospital. Dexmedetomidine (DEX) has been shown to have anti-inflammatory effects.
- Conditions
- Spinal Fusion Acquired, Spinal Stenosis, Lesions of Lumbosacral Intervertebral Disc, Spinal Diseases
- Trial name
- DEXREDLOS (NCT00808665)
- Testing
- Dexmedetomidine, 0.9% Saline
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Vanderbilt University Medical Center