Clinical trials: Contraceptive Methods
Body Weight, Contraceptive Usage
Oral Contraceptives and Body Mass Index
The main hypothesis for this study is that increased Body Mass Index (BMI) alters oral contraceptive metabolism in a manner which results in decreased effectiveness in obese women.
- Trial name
- NCT01170390
- Testing
- All participants (Aviane), Portia, Aviane
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Open-label Study to Evaluate the Efficacy and Safety of an Extended-cycle, Low Dose Combination Oral Contraceptive
This is an open-label, single treatment study. All subjects will receive one year of oral contraceptive therapy with DR-1011. Study participants will receive physical and gynecological exams, including Pap smear.
- Trial name
- NCT00196326
- Testing
- DR-1011
- Where
- 55 sites in United States
- Volunteers
- 2,235 people, healthy volunteers welcome
- Sponsor
- Duramed Research
Bleeding, Implants
Treatment of Unfavorable Bleeding Patterns in Contraceptive Implant Users
The etonogestrel (ENG) subdermal contraceptive implant (ENG implant) is a highly effective method of preventing pregnancy, but it has bleeding side effects that make it unappealing for many women.
- Conditions
- Bleeding, Implants, Breakthrough Bleeding
- Trial name
- Tamoxifen/BTB (NCT02903121)
- Testing
- Tamoxifen, Tamoxifen (open label)
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception, Contraceptive Behavior
Patient-Centered Support for Contraceptive Decision-Making
The investigators have designed a tablet-based decision support tool to help women learn more about their birth control options and support them in choosing a method they are happy with.
- Trial name
- NCT02078713
- Testing
- Contraceptive Decision Support Tool
- Where
- 4 sites in United States
- Volunteers
- 786 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pregnancy in Adolescence, Counseling
Reducing Adolescent Pregnancy
This multi-site study is employing a brief contraception counseling intervention in the Emergency Department (ED) to shed light on factors that affect decision making as well as barriers and facilitators to conception initiation…
- Conditions
- Pregnancy in Adolescence, Counseling, Contraception Behavior
- Trial name
- NCT04120376
- Testing
- Contraception Counseling
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Pregnancy Prevention
Oral Levonorgestrel Plus Meloxicam, IG-002 Delays Ovulation in Normal Menstruating Women by Seven Days
This clinical trial determines if an oral medication taken within 2 days of anticipated ovulation will delay ovulation by 7 days.
- Trial name
- OVULATION (NCT05695352)
- Testing
- Levonorgestrel 1.5mg, Meloxicam 15 mg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- InnovaGyn, Inc.
Contraception, Body Weight
Emergency Contraception and Body Weight: Pilot Study
The purpose of this research study is to determine how body weight changes the drug level of an emergency contraceptive pill containing a hormone called levonorgestrel (LNG).
- Trial name
- NCT02408692
- Testing
- ECx1, ECx2
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Levonorgestrel Contraceptive Intrauterine Systems (LCS) Pearl Index Study
This is a study on a new low dose levonorgestrel contraceptive intrauterine systems (LCS). The purpose of the study is to investigate which of the 2 administered doses is the lowest effective intrauterine dose of Levonorgestrel…
- Trial name
- NCT00528112
- Testing
- LCS12, LCS16
- Where
- 136 sites in United States, Argentina and 9 more
- Volunteers
- 2,885 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
Pharmacokinetic and Pharmacodynamic Study of Cyclofem
Cyclofem® is a monthly injectable contraceptive containing 25 mg of medroxyprogesterone acetate (MPA) and 5 mg of estradiol cypionate (E2C), a long-acting ester of estradiol.
- Trial name
- NCT01699022
- Testing
- Injection Cyclofem
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries Limited
Contraception
Safety, Efficacy, Tolerability and Pharmacokinetics of LF111 (Drospirenone 4.0 mg) During 13 Cycles
To demonstrate the contraceptive efficacy of LF111 . To demonstrate the safety and tolerability of LF111 and assessment of pharmacokinetics of LF111.
- Trial name
- NCT02269241
- Testing
- LF111 (drospirenone)
- Where
- 37 sites in United States
- Volunteers
- 1,552 people, healthy volunteers welcome
- Sponsor
- Laboratories Leon Farma, S.A.
Contraception
Study of the Safety, and Sperm and Gonadotropin Suppression of a Contraceptive Gel in Normal Men
To determine the number of men who have suppression of sperm production when using a daily regimen of Nestorone® Gel (0, 8 or 12 mg) and Testosterone Gel applied transdermally.
- Trial name
- CCN007 (NCT00891228)
- Testing
- Testosterone, Nestorone®
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Premier Research
Contraception, Hypogonadism
ORAL T-6: Oral Androgens in Man-6
We propose a study to determine the single-dose pharmacokinetics of these two novel formulations of testosterone in normal men with experimentally induced hypogonadism.
- Trial name
- ORAL-T-6 (NCT00663793)
- Testing
- Acyline, Testosterone, Finasteride
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Washington
Contraception
Enhancing Male Participation in Interventions to Prevent Unintended Pregnancy
Globally, 41% of all pregnancies are unintended, increasing risk for maternal and infant morbidity and mortality. Most unintended pregnancies occur in the context of contraceptive non-use or failure.
- Trial name
- CHARM2 (NCT03514914)
- Testing
- The CHARM2 Intervention
- Where
- India
- Volunteers
- 2,402 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Weight Gain, Disorder of Bone Density and Structure, Unspecified
Drug Exposure and Depot Medroxyprogesterone Acetate (DMPA) in Adolescent Subjects
The investigators are doing this study to look at how different doses of the Depot medroxyprogesterone acetate (DMPA) shot effect weight gain and bone mineral density in teens.
- Conditions
- Weight Gain, Disorder of Bone Density and Structure, Unspecified, Uterine Bleeding
- Trial name
- NCT01461824
- Testing
- Depot medroxyprogesterone acetate (DMPA)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Pain Due to Intrauterine Contraceptive Device
Pain Control for Intrauterine Device Placement Using Paracervical Block
Intrauterine device (IUD) placement can be painful for patients during and after the procedure. Fear of pain from IUD insertion can be a barrier to obtaining this highly effective long acting reversible contraception.
- Trial name
- NCT02219308
- Testing
- Paracervical Block (PCB)
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breastfeeding, Contraception
Safety of the Etonogestrel-releasing Implant During the Puerperium of Healthy Women
The purpose of this study to assess the safety of the etonogestrel-releasing subdermal implant (Implanon) inserted during the immediate puerperium of healthy women.
- Trial name
- NCT00828542
- Testing
- etonogestrel implant, depot medroxyprogesterone acetate
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Contraception
Naproxen for Pain Control With Intrauterine Device Insertion
The purpose of this study is: 1. To evaluate whether 550 mg of naproxen sodium reduces pain scores with IUD insertion on a 0-10cm visual analogue scale compared to placebo (primary outcome). 2.
- Trial name
- NCT02388191
- Testing
- Naproxen sodium
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Contraception
Study of the Use of a Contraceptive Vaginal Ring (NuvaRing) in Normal Daily Practice in Indian Women (P07733)
This study will collect information on cycle control, acceptability and tolerability of the vaginal contraceptive ring (NuvaRing) as used in normal daily practice by Indian women.
- Trial name
- NCT01490190
- Testing
- Ethinylestradiol + Etonogestrel Vaginal Ring (NuvaRing)
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Contraception
Continuation of Subcutaneous and Intramuscular Depot Medroxyprogesterone Acetate in Post-abortion Patients
Multiple prior studies have compared self-administered Subcutaneous Depot Medroxyprogesterone Acetate(DMPA-SC) to both provider-administered DMPA-SC and Intramuscular Depot Medroxyprogesterone Acetate (DMPA-IM) and found that…
- Trial name
- NCT05505435
- Testing
- Depot-Medroxyprogestereone Acetate
- Where
- United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Contraceptive Usage, Alcohol Use Complicating Childbirth
Native-Changing High-risk Alcohol Use and Increasing Contraception Effectiveness Study
Native CHOICES is a randomized controlled trial of an adapted intervention to reduce the risk of alcohol exposed pregnancies in American Indians and Alaska Natives (AI/ANs).
- Conditions
- Contraceptive Usage, Alcohol Use Complicating Childbirth, Alcohol Drinking
- Trial name
- Native-CHOICES (NCT03930342)
- Testing
- Native-CHOICES
- Where
- 2 sites in United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Washington State University