Clinical trials: Contrast Agent
Ischemic Stroke
Contrast Enhanced Sonothrombolysis and Sonolysis in Stroke - a Swedish Study (CE-5S)
Patients with acute ischemic stroke in anterior circulation within 4,5 hours of symptom onset, has a bone window and Trombolysis In Brain Ischemia (TIBI) <=4 in a relevant artery eligible.
- Trial name
- CE-5S (NCT03290053)
- Testing
- SonoVue, Sodium chloride, Transcranial Ultrasound
- Where
- Sweden
- Volunteers
- 1 people
- Sponsor
- Umeå University
Hepatocellular Carcinoma (HCC)
Contrast (Sonazoid)-Enhanced US as a Screening Tool for Hepatocellular Carcinoma in Cirrhosis: An Exploratory Cross-sectional Study
B-mode ultrasonography (B-US), a standard method of surveillance of hepatocellular carcinoma (HCC), has a fair sensitivity of 63% in detecting early stage HCC.
- Trial name
- NCT02188901
- Testing
- Sonazoid-enhanced ultrasonography
- Where
- South Korea
- Volunteers
- 523 people
- Sponsor
- Yonsei University
Contrast-Associated Acute Kidney Injury, Acute Kidney Injury
Contrast Volume as a Predictor of Kidney Injury Following Contrast-Enhanced CT
Iodinated contrast dye used during computed tomography (CT) scans can sometimes cause kidney stress or damage, known as contrast-associated acute kidney injury (CA-AKI).
- Conditions
- Contrast-Associated Acute Kidney Injury, Acute Kidney Injury, Contrast-Induced Nephropathy, Acute Renal Failure
- Trial name
- NCT07813819
- Volunteers
- 1,112 people
- Sponsor
- Assiut University
Crohn Disease
Evaluation of a New Oral Contrast Agent for MR Enterography in the Assessment of Crohn Disease in the Small Bowel
The purpose of this study is to assess the exam quality and accuracy of MR using a new oral contrast agent for the evaluation of Crohn Disease in the small bowel.
- Trial name
- NCT00587210
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Mayo Clinic
Pancreatic Neoplasms, Pancreatitis
Contrast EUS of the Pancreas
RATIONALE: Endoscopic Ultrasound (EUS) is the leading method to evaluate the pancreas but there may be difficulty characterizing small lesions, tumors which are not adenocarcinomas and neoplasia in the setting of pancreatitis.
- Conditions
- Pancreatic Neoplasms, Pancreatitis, Pancreatic Cyst
- Trial name
- NCT02863770
- Testing
- EUS enhanced with contrast to evaluate pancreas
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Southern California
Liver Tumors
Evaluation of Intra-operative Ultrasound Contrast Enhancement in the Evaluation of Liver Tumors
The primary purpose of this study is to demonstrate the safety and effectiveness of using an intra-operative ultrasound contrast agent(Definity®) for the identification of known liver tumors.
- Trial name
- Definity® (NCT00955097)
- Testing
- Definity®
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Louisville
Interventional Neuroradiology
Optimizing Reduced-Flow, Low-Volume Contrast Protocols for Cerebral Angiography in Unruptured Aneurysms
Over the past two decades, interventional neuroradiology (INR) has seen significant advances in terms of safety and radiation protection.
- Trial name
- OPIAC (NCT07302646)
- Testing
- Standard (Reference), Reduced volume - standard flow rate, Standard volume - Reduced flow rate
- Where
- France
- Volunteers
- 244 people
- Sponsor
- University Hospital, Strasbourg, France
Hypothyroidism
Thyroid Function of Pediatric Subjects Following Isovue® Administration
This is a Phase IV prospective, multicenter, observational study to estimate the proportion of subjects 0 to 3 years of age who develop abnormal thyroid function after exposure to intravascular administration of ISOVUE for the…
- Trial name
- NCT03779906
- Testing
- Isovue
- Where
- 4 sites in United States
- Volunteers
- 17 people
- Sponsor
- Bracco Diagnostics, Inc
Coronary Artery Disease
Short-Term Exposure to Lipophilic Anti-proliferative Drugs Delivered by Angiographic Contrast Media
This was a randomized, placebo-controlled, multi-centre study, double-blind within each dose level, with four ascending dose levels to test the tolerability and safety of iopromide-paclitaxel in patients with de novo lesions in…
- Trial name
- NCT01140204
- Testing
- Implantation of a bare metal stent
- Where
- 2 sites in Germany
- Volunteers
- 32 people
- Sponsor
- University Hospital, Saarland
NET, Radionucleide Therapy
DCEUS to Assess Treatment Response to PRRT in GEP-NET
Neuroendocrine tumors (NETs) are a wide group of neoplasms arising from the diffuse neuroendocrine cell system that features significant molecular and biological heterogeneity.
- Conditions
- NET, Radionucleide Therapy, Contrast Enhanced Ultrasound
- Trial name
- DCEUS-PRRT (NCT07319416)
- Testing
- Vuebox
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coronary Artery Disease
Familiarization and Safety Study of PB127 Ultrasound Contrast Agent
The purpose of this study is to evaluate preparation and administration of PB127, echocardiographic images obtained during PB127 administration, and evaluate the safety of PB127.
- Trial name
- NCT00594698
- Testing
- PB127 for injectable suspension
- Where
- 34 sites in United States
- Volunteers
- 150 people
- Sponsor
- Point Biomedical
Nicotine Dependence, Vaping
Influence of the Consumption of Conventional and Electric Cigarettes on Skin Circulation
The survey participants are divided into a smoking and non-smoking group. The smoker group is further divided according to the quantity and quality of nicotine ("normal" smoking, vaping).
- Conditions
- Nicotine Dependence, Vaping, Smoking
- Trial name
- NCT04645914
- Testing
- Use of nicotine product (smoking/vaping)
- Where
- Germany
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Brain Tumor, Primary
Intra-operative Variation in Size of Brain Tumors After Craniotomy
We planned to evaluate the change in tumor dimensions of intraaxial parenchymal tumors after craniotomy by comparing the tumor size on intraoperative ultrasonography (IOUSG) with pre-operative CECT and CEMRI brain.
- Trial name
- NCT04365647
- Where
- India
- Volunteers
- 51 people
- Sponsor
- Sheri Kashmir Institute of Medical Sciences
Primary CNS Lymphoma (PCNSL)
Treatment of Primary CNS Lymphoma
The purpose of this study is to evaluate the efficacy and safety of FVD regiment (fotemustine, teniposide and dexamethasone ) for patients with primary CNS lymphoma.
- Trial name
- FVD (NCT01960192)
- Testing
- HD-MTX-Ara-C regimen, FVD regimen
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Mingzhi Zhang
Colorectal Neoplasms, Neoplasm Metastasis
Health Economic Evaluation of Primovist-enhanced Liver MRI
Patients with a history of colorectal cancer and known or suspected liver metastases who are scheduled for contrast-enhanced tomographic imaging will be included in this study.
- Trial name
- NCT00764621
- Testing
- Primovist MRI, Extracellular contrast media (ECCM) MRI, Contrast-enhanced CT
- Where
- 44 sites in Austria, Germany and 7 more
- Volunteers
- 360 people
- Sponsor
- Bayer
Evaluation of Troponin I Levels
Prospective Analysis and Comparison of Stress Echo to Real-Time Myocardial Contrast Stress Echo
The purpose of this study is to prospectively analyze and compare conventional stress echocardiograms and real-time myocardial contrast stress echocardiograms; and to determine the effect of contrast agents used during real-time…
- Trial name
- NCT00575549
- Testing
- Dobutamine: Perflutren Lipid Microsphere
- Where
- United States
- Sponsor
- University of Nebraska
Adenocarcinoma Pancreas, Chronic Pancreatitis
Contrast Enhanced Harmonic Endoscopic Ultrasound (CEH-EUS) in Focal Pancreatic Masses
The aim of the study is to assess the accuracy of real-time perfusion imaging pattern of pancreatic focal lesions visualized by contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) for the differential diagnosis between…
- Trial name
- NCT01315548
- Where
- 14 sites in Denmark, France and 6 more
- Volunteers
- 210 people
- Sponsor
- University of Medicine and Pharmacy Craiova
Magnetic Resonance Imaging, Tetralogy of Fallot
4D Velocity Mapping of the Heart in rTOF Patients
MRI with 4D flow permits to assess the hemodynamic parameters in a parent vessel and its branches inside the same sequence.
- Trial name
- CARDIOFLUX (NCT02980614)
- Testing
- 4D flow imaging
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Acute Ischaemic Stroke
Magnetic Resonance Post-contrast Vascular Hyperintensities at 3 T: a Sensitive Sign of Vascular Occlusion in Acute Ischaemic Stroke
Magnetic resonance imaging (MRI) is the diagnostic cornerstone for precisely identifying acute ischaemic strokes and locating vascular occlusions.
- Trial name
- NCT03971526
- Testing
- MRI images review
- Volunteers
- 130 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Ischaemic Heart Disease, Contrast-induced Nephropathy
Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients
A large number of patients with symptomatic ischaemic heart disease undergo coronary artery bypass grafting (CABG) to alleviate their symptoms and improve prognosis.
- Trial name
- BYPASS-CTCA (NCT07022626)
- Testing
- CTCA
- Where
- 2 sites in United Kingdom
- Volunteers
- 688 people
- Sponsor
- Barts & The London NHS Trust
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