Clinical trials: Contrast Agent
Crohn Disease, Ultrasound Therapy; Complications
Correlation of Cross Sectional Imaging and Small Intestinal Contrast Ultrasonography in Known Crohn's Disease
Small intestinal contrast ultrasound (SICUS) is a modality of intestinal ultrasound (IUS) which does not require any parenteral administration of contrast agent but requires ingestion of around 500 ml of polyethylene glycol…
- Conditions
- Crohn Disease, Ultrasound Therapy; Complications, Computed Tomography, Magnetic Resonance Imaging
- Trial name
- CACTUS-CD (NCT06125678)
- Testing
- Small intestinal contrast enhanced ultrasound followed by Computed tomography/Magnetic resonance enterography
- Where
- India
- Volunteers
- 407 people
- Sponsor
- Asian Institute of Gastroenterology, India
Chagas Cardiomyopathy
Microvascular Endothelial Function in a Cohort of Patients With the Cardiac Form of Chronic Chagas Disease.
The present study aims to evaluate the microvascular endothelial function of a single centre cohort of patients with the cardiac form of Chagas disease, and to search for associations with clinical and laboratory variables.
- Trial name
- NCT03524768
- Testing
- skin laser speckle contrast imaging and video-capillaroscopy
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Cataracts, Visual Acuity Reduced Transiently
The Incidence of Glistenings in the 2017 Intraocular Lenses Made by Alcon and Abbott Medical Optics
The purpose of this study is to seek academic/non-industry research funding support to independently investigate the incidence and density of lens glistenings in cataract patients who are implanted with the latest generations of…
- Conditions
- Cataracts, Visual Acuity Reduced Transiently, Loss of Visual Contrast Sensitivity, Functional Visual Loss
- Trial name
- NCT03409185
- Testing
- Alcon 1 piece SA60AT lens, AMO 1-piece AABOO lens
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Toronto
Contrast Enhanced Ultrasound
Diagnostic Value of Sonazoid Contrast-enhanced Ultrasound in Renal Tumors
The incidence and mortality of renal cell carcinoma are increasing year by year. Contrast-enhanced ultrasound is helpful for early diagnosis and treatment to renal tumor, and is of great importance to distinguish benign from…
- Trial name
- NCT04626115
- Where
- China
- Volunteers
- 223 people
- Sponsor
- Chinese PLA General Hospital
Carotid Atherosclerosis, Ultrasound
3D Contrast Enhanced Microvascular Ultrasound of Carotid Atherosclerosis for the Detection of Carotid Plaque Neo-Revascularisation.
Atherosclerotic plaques, the build-up of fatty materials within our arteries, can develop over a long period of time without causing any symptoms.
- Conditions
- Carotid Atherosclerosis, Ultrasound, Plaque Neovascularization
- Trial name
- Carotid Neo3D (NCT07298655)
- Testing
- 3D Contrast Enhanced Microvascular Carotid Ultrasound
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- London North West Healthcare NHS Trust
Acute Kidney Injury
Effect of Darbepoetin in Contrast-induced Nephropathy
The purpose of this study is to determine whether the drug that produce red blood cells is effective in the prevention of kidney dysfunction after coronary angiography in patients with chronic kidney disease.
- Trial name
- NCT01197235
- Testing
- darbepoetin-α, isotonic saline
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
Magnetic Resonance Angiography, Contrast Media
Improving the Concentration of MR Contrast in the Arteries
In Contrast-Enhanced Magnetic Resonance Angiography (CE-MRA) a contrast agent is injected into an arm vein using a programmable medical device called a power injector.
- Trial name
- NCT02155218
- Testing
- Standard Injection Rate, Patient Tailored Injection Rate, gadolinium contrast
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Washington
Healthy
Technical Development of Interventional Cardiovascular Magnetic Resonance Imaging in Normal Volunteers
This study will test new techniques to image the heart, blood vessels, and legs using magnetic resonance imaging (MRI). The techniques will be used to plan and guide treatments using minimally invasive methods.
- Trial name
- NCT00720460
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Liver Metastasis Colon Cancer
Sonazoid-enhanced Ultrasound for the Detection of Colorectal Liver Metastases Less Than 2 cm
Preoperative chemotherapy is often used for patients with colorectal cancer liver metastasis (CLM). Many small CLMs (<=2cm) may disappear after chemotherapy, while most of these are still alive.
- Trial name
- NCT04686942
- Testing
- After sonazoid
- Where
- China
- Volunteers
- 550 people
- Sponsor
- Sun Yat-sen University
Contrast Induced Nephropathy
Effect of Sodium Bicarbonate Solution in Decreasing the Incidence of Contrast Induced Nephropathy (CIN)
Radio Contrast Induced Nephropathy (RCIN) remains a well recognized complication in patients undergoing diagnostic or interventional procedures requiring radiographic contrast agents.
- Trial name
- NCT00514150
- Testing
- Sodium Bicarbonate plus normal saline 0.9%, normal saline 0.9%
- Where
- Iran
- Volunteers
- 265 people
- Sponsor
- Tehran University of Medical Sciences
IV Contrast Dosing
Use of Electrical Impedence to Measure Lean Body Weight as a Determinant of the Dose of Contrast Media for Abdominal CT
There are several different methods that can be used to determine the dose of iodinated contrast material for a CT scan. These include a standard fixed dose, a dose based on total body weight, a dose based on body mass index, a…
- Trial name
- NCT02170688
- Testing
- Isovue 370, Weight calculation
- Volunteers
- 139 people
- Sponsor
- Duke University
Hearing in Noise
Speech Perception, Spatial Perception and Satisfaction Outcomes of Fitting Based on Hearing In Noise Ability
Hearing speech in the presence of background noise is a significant challenge for those with hearing loss. Being able to hear speech in noise has been rated as the most sought-after feature in hearing aids by hearing aid users.
- Trial name
- NCT07756970
- Testing
- ACT method in fitting, Traditional fitting
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul Aydın University
Contrast-induced Nephropathy, Kidney Injury
Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease
The use of contrast media (CM) poses a risk of post-contrast acute kidney injury (PC-AKI), especially among patients chronic kidney disease (CKD).
- Conditions
- Contrast-induced Nephropathy, Kidney Injury, Kidney Failure, Chronic, Risk Reduction
- Trial name
- ENRICH (NCT05283512)
- Testing
- Preventive treatment with IV-hydration, Preventive treatment with oral hydration
- Where
- Denmark
- Volunteers
- 254 people
- Sponsor
- Odense University Hospital
Prostate Cancer
Contrast Enhanced Transrectal Ultrasonography (TRUS) to Assess Prostatic Vascularity After Radiotherapy (XRT)
Solid tumors, including prostate cancer, commonly exhibit tumor-associated neovascularity (growth of new blood vessels to feed the tumor) with increased microvessel density.
- Trial name
- NCT00635167
- Testing
- Contrast Enhanced-Transrectal Ultrasound
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Ultrasonography, Carotid Stenosis
Prognostic Value of Carotid CEUS in Acute Ischemic Stroke Patients
Contrast-enhanced ultrasound(CEUS) of carotid artery plaque is a novel method that enabled direct visualization of neovessels in the vulnerable plaque.
- Conditions
- Ultrasonography, Carotid Stenosis, Ischemic Stroke
- Trial name
- NCT03283306
- Where
- South Korea
- Volunteers
- 667 people
- Sponsor
- Seoul National University Hospital
KIDNEY FAILURE, ACUTE
Prevention of Contrast Induced Nephropathy (NIC) by Intravenous Versus Oral Rehydration
The purpose of this study is to compare the efficacy of oral versus intravenous hydration in the prevention of the contrast-induced nephropathy.
- Trial name
- NIC (NCT00908843)
- Testing
- Intravenous hydration with bicarbonate, Oral hydration with Sodium solution
- Where
- Spain
- Volunteers
- 167 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Raynaud Disease, Scleroderma, Systemic
Laser Speckle Contrast Imaging for Cutaneous Microvascular Dysfunction Detection in Systemic Sclerosis.
The aim of the study is to determine if postocclusive hyperemia of palmar and dorsal face of the hand with Laser speckle contrast imaging discriminate between patients with systemic sclerosis, subjects with primary Raynaud's…
- Trial name
- SPECIES (NCT01743612)
- Testing
- laser speckle contrast imaging, Cooling
- Where
- 2 sites in France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Breast Cancer
Enhanced Ultrasound in Determining Extent of Disease in Women With Primary Breast Cancer
RATIONALE: New imaging procedures, such as enhanced ultrasound may improve the ability to determine the extent of breast cancer.
- Trial name
- NCT00005058
- Testing
- ultrasound imaging
- Where
- United Kingdom
- Sponsor
- Royal Marsden NHS Foundation Trust
Intraocular Lens
Visual Outcomes and Contrast Sensitivity in Patients Implanted With Tecnis Eyhance Intraocular Lens
To compare visual outcomes for various distances, reading speed, contrast sensitivity, glare occurence, defocus curve and subjective satisfaction in patients implanted with the extended depth of focus lens (Tecnis Eyhance) in one…
- Trial name
- NCT04800887
- Testing
- TECNIS Eyhance intraocular lens, Monofocal intraocular lens Tecnis ZCB00
- Where
- Czechia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Pain
The Effect of Pretreatment With Intravenous Lidocaine for Intravenous Contrast:
Intravenous contrast media is commonly used for CT scans for improved image clarity in pediatric emergency medicine. Children who feel discomfort during the administration of IV contrast media may not remain still during the CT…
- Trial name
- NCT05143489
- Testing
- Preservative Free Lidocaine, Saline
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Antonios Likourezos
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