Clinical trials: Contrast Agent
Thyroid Nodule
Artificial Intelligence-assisted Contrast-enhanced Ultrasound Diagnosis of Thyroid Nodules
The goal of this intervention study is to learn about the diagnostic performance of artificial intelligence to assist the contrast-enhanced ultrasound diagnosis of thyroid nodules. The main questions it aims to answer are: 1.
- Trial name
- AIA-CEUD-TN (NCT05982821)
- Testing
- Artificial Intelligence
- Where
- China
- Volunteers
- 1,955 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Retroperitoneal Neoplasms
Contrast-enhanced vs. B-mode Ultrasound-guided Percutaneous Biopsy of Retroperitoneal Tumors
Background: Retroperitoneal tumors are typically large and inhomogeneous, with a variable amount of necrosis within the tumor mass which decreases the diagnostic yield of biopsy (false negative or inadequate).
- Trial name
- NCT05659433
- Testing
- CEUS-guided percutaneous biopsy, B-mode US-guided percutaneous biopsy
- Where
- Romania
- Volunteers
- 160 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Abdominal Trauma
Contrast Enhanced Ultrasound for Evaluation of Pediatric Abdominal Trauma
The research protocol aims to compare the utility of contrast enhanced abdominal sonography with computerized tomography in the evaluation of children with blunt abdominal trauma.
- Trial name
- NCT01763840
- Testing
- Contrast enhanced Ultrasound
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- David Mooney
Hepatocellular Carcinoma, Cholangiocarcinoma, Intrahepatic
Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study
Aim of this prospective national multicenter study is to improve standardization of contrast-enhanced ultrasound (CEUS) in the non-invasive diagnosis of hepatocellular carcinoma (HCC) in high-risk patients.
- Conditions
- Hepatocellular Carcinoma, Cholangiocarcinoma, Intrahepatic, Liver Cirrhosis, Liver Cancer
- Trial name
- ESCULAP (NCT03405909)
- Testing
- contrast enhanced ultrasound (CEUS), MRI, Histology
- Where
- Germany
- Volunteers
- 517 people
- Sponsor
- University Hospital Erlangen
Macular Degeneration
Evaluation of Visual Function and Driving Health Using Ocusweep in Patients Suffering From Wet Age-related Macular Degeneration
The aim is to study the use of Ocusweep system especially in driving health evaluation and compare the results produced by Ocusweep system to those of conventional devices.
- Trial name
- NCT02747368
- Testing
- Ocusweep system
- Volunteers
- 600 people
- Sponsor
- Turku University Hospital
Non Mass Breast Lesions
Diagnostic Accuracy of Multiparametric Dynamic Contrast Enhanced Magnetic Resonance Imaging in Improving Detection of Ultrasound Non-mass Breast Lesions According to ACR BI-RADS v2025
this study aims To evaluate the diagnostic performance of Ultrasound (US) in correlation with Dynamic Magnetic Resonance Imaging (MRI) for the assessment, characterization, and evaluation of non-mass breast lesions.
- Trial name
- NCT07679308
- Testing
- multiparametric DCE- MRI and US for all patients
- Volunteers
- 60 people
- Sponsor
- Sohag University
Hepatocellular Cancer, Liver Cirrhoses
Comparing the Diagnostic Efficiencies of CEUS and EOB-MRI in Patients With High Risk of HCC
HCC is a serious threat to the health of people. Accurate diagnosis of early HCC by imaging allows patients to obtain proper treatment.
- Conditions
- Hepatocellular Cancer, Liver Cirrhoses, Diagnoses Disease
- Trial name
- NCT04212286
- Testing
- Diagnostic CEUS and EOB-MRI
- Where
- China
- Volunteers
- 115 people
- Sponsor
- Tianjin Third Central Hospital
Coronary Artery Disease
Safety and Efficacy Study of PB127 Ultrasound Contrast Agent in Patients With Suspected Coronary Artery Disease 007
This trial is to compare PB127 echocardiography to other heart imaging studies.
- Trial name
- NCT00595673
- Testing
- PB127 for injectable suspension
- Where
- 19 sites in United States
- Volunteers
- 428 people
- Sponsor
- Point Biomedical
Non-small Cell Lung Cancer
Predictive Value of FDG PET/CT, DWI and DCE-MRI Scans for Non-small Cell Lung Cancer Patients Receiving Chemotherapy
In this prospective study, the investigators will evaluate and compare the usefulness of functional and volumetric informations obtained by 18F-FDG PET and MRI before and after the palliative chemotherapy with the aim of…
- Trial name
- NCT01482182
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Samsung Medical Center
Healthy Volunteers
Dynamic Magnetic Resonance Imaging of Human Subarachnoid Space Using Intrathecal Gadolinium Contrast
Background: Cerebrospinal fluid (CSF) is the liquid that fills the space around the brain and spinal cord. Researchers do not fully understand how CSF flows and drains around the brain.
- Trial name
- NCT07796360
- Testing
- Gadobutrol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Neuroendocrine Tumors
Nonfunctioning Small (≤2 cm) Neuroendocrine Pancreatic Incidentaloma
Neuroendocrine tumors (NETs) and carcinomas account for 10-15 % of all pancreatic incidentalomas. The management of pancreatic NETs depends on tumor stage and on presence or not of hormonal syndrome.
- Trial name
- NCT03022188
- Where
- 22 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- Société Française d'Endoscopie Digestive
Breast Cancer
Breast VCEUS to Evaluate Early Response to Neoadjuvant Chemotherapy
1. Evaluate quantitative VCEUS imaging for determining early breast cancer response to neoadjuvant chemotherapy and compare results to co-temporal volume change on grayscale ultrasound and post-treatment mammography findings…
- Trial name
- NCT01817374
- Testing
- 2D US grayscale plus quantitative VCEUS
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Alabama at Birmingham
Breast Cancer
A Study of Contrast-Enhanced Mammography (CEM) Scans in People With Breast Cancer
The purpose of this study is to find out whether Contrast-Enhanced Mammography/CEM scans performed 2 minutes and 6 minutes after receiving Iohexol contrast dye can be used to identify the amount of residual disease in the breast…
- Trial name
- NCT05990478
- Testing
- Contrast-Enhanced Mammography, Breast MRI
- Sponsor
- Memorial Sloan Kettering Cancer Center
Percutaneous Coronary Intervention
Adenosine Contrast CorrELations in Evaluating RevAscularizaTION
The purpose of this study is to compare FFR measurements done with adenosine to FFR measurements done with contrast, where the contrast is injected using the ACIST CVi automated contrast injector.
- Trial name
- ACCELERATION (NCT03557385)
- Testing
- Iopamidol, adenosine, Navvus® Catheter
- Where
- 5 sites in United States
- Volunteers
- 201 people
- Sponsor
- Duke University
Infertility
Warming Contrast Media for Hysterosalpingography
The purpose of this study is to compare the use of warm-media with cold-media in performing hysterosalpingography (HSG).
- Trial name
- NCT01339338
- Testing
- warming the contrast media
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Taizhou Hospital
Rheumatoid Arthritis
Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Measure Response to Etanercept in Rheumatoid Arthritis
The purpose of this study is to assess whether DCE-MRI can detect changes of active disease in rheumatoid arthritis (RA) patients after 4, 8 and 12 weeks of etanercept.
- Trial name
- NCT00361634
- Testing
- Etanercept
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 14 people
- Sponsor
- Amgen
Complications of Perfusion
Real-time Quantitative Optical Perfusion Imaging in Surgery
Surgeons are nowadays unable to visualize and quantitatively evaluate microvascularisation in real-time during surgery. Complications due to vascular compromise are a major problem, especially in reconstructive surgery.
- Trial name
- NCT02902549
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Glaucoma
Spaeth/Richman Contrast Sensitivity Test
The Spaeth-Richman Contrast Sensitivity (SPARCS) test is a new method of assessing contrast sensitivity. The test, another way to measure vision, is performed on any standard computer with internet access.
- Trial name
- SPARCS (NCT01300949)
- Testing
- Spaeth/Richman Contrast Sensitivity Test, Pelli-Robson Contrast Sensitivity Chart
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Left Cardiac Catheterization, Percutaneous Coronary Intervention
Dapagliflozin to Prevent the Incidence of Contrast Induced Nephropathy After Heart Catheterization and Percutaneous Coronary Intervention
Left heart catheterization and percutaneous coronary intervention (PCI) has become a useful tool in interventional cardiology, in which iodinated contrast media is used.
- Conditions
- Left Cardiac Catheterization, Percutaneous Coronary Intervention, Acute Kidney Injury, Sodium-glucose Co-transporter 2 Inhibitors
- Trial name
- NCT04806633
- Testing
- Dapagliflozin 5mg
- Where
- 2 sites in Greece
- Volunteers
- 1,722 people
- Sponsor
- G.Gennimatas General Hospital
Gastric Cancer Stage, Gastric Cancer Patients Undergoing Gastrectomy
AI-Assisted Detection and Staging of Gastric Cancer Using Contrast-Enhanced CT
Accurate preoperative assessment of gastric cancer stage guides eligibility for endoscopic resection, extent of gastrectomy and lymphadenectomy, selection for neoadjuvant therapy, and use of staging laparoscopy.
- Trial name
- NCT07250347
- Testing
- CT scan
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
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