Clinical trials: Contrast Agent
Heart Failure, Pulmonary Vascular Disease
Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume
The purpose of this study is to evaluate whether pulmonary blood volume (PBV) derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise.
- Trial name
- NCT06195059
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Mayo Clinic
Healthy
A Healthy Volunteer Trial Investigating MR-enterography Image Quality of Lumentin® 44
A healthy volunteer, open, PoC single center trial investigating a new oral contrast agent for use in combination of MR examination of the abdomen and pelvis.
- Trial name
- NCT05781490
- Testing
- Lumentin® 44 Powder for oral foam
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lument AB
Sepsis Induced Myocardial Dysfunction
The Treatment of Sepsis Induced Myocardial Dysfunction With Yiqilishui Formula
The goal of this clinical trial is to learn if Chinese medicine - Yiqilishui formula works to treat sepsis-induced myocardial dysfunction (SIMD). It will also learn about the safety of Yiqilishui formula.
- Trial name
- YQSIMD (NCT06686355)
- Testing
- Yiqilishui formula
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Dongzhimen Hospital, Beijing
Amblyopia, Anisometropic Amblyopia
Augmented Reality-Based Binocular Therapy for Visual Rehabilitation in Adults With Amblyopia
The goal of this clinical trial is to evaluate a home-based augmented reality-based binocular therapy designed to improve visual function in adults aged 18 to 40 years with unilateral anisometropic amblyopia, commonly called…
- Trial name
- Ambly4Home (NCT07819552)
- Testing
- Active Augmented Reality-Based Binocular Therapy
- Where
- 2 sites in Portugal
- Volunteers
- 60 people
- Sponsor
- Polytechnic Institute of Porto
Breast Cancer
Fluorescent Dyes for Lymph Node Mapping
The goal of this clinical research study is to find lymph nodes before surgery using a dye called indocyanine green (IC-Green). Objectives: 1.
- Trial name
- NCT01095913
- Testing
- Indocyanine green (ICG)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Focal Liver Lesions, Liver Cancer
Characterization of Focal Liver Lesions by Real-time Contrast-enhanced Ultrasound Imaging (CEUS)
The conventional sonography is frequently used to detect incidental focal liver lesions because of its availability, innocuity and low cost.
- Conditions
- Focal Liver Lesions, Liver Cancer, Liver Cirrhosis
- Trial name
- NCT00243633
- Testing
- Real-time contrast-enhanced ultrasound sonography
- Where
- 15 sites in France
- Volunteers
- 878 people
- Sponsor
- University Hospital, Tours
Infertility
Warm Contrast Media for Pain Reduction During Hystersalpingography
The aim of this study is to compare between body-temperature to room-temperature contrast media used during hysterosalpingography. We hypothesize that warmed medium will reduce pain associated with the procedure.
- Trial name
- NCT00391781
- Testing
- Temperature of contrast medium
- Where
- Israel
- Sponsor
- Shaare Zedek Medical Center
Rheumatoid Arthritis
Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Measure Response to Etanercept in Rheumatoid Arthritis
The purpose of this study is to assess whether DCE-MRI can detect changes of active disease in rheumatoid arthritis (RA) patients after 4, 8 and 12 weeks of etanercept.
- Trial name
- NCT00361634
- Testing
- Etanercept
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 14 people
- Sponsor
- Amgen
Aneurysm, AVM
Intraoperative Laser Speckle Contrast Imaging to Assess Blood Flow During Neurosurgery
Cerebral blood flow (CBF) is of paramount importance to human brain function, as the brain relies on a continuous blood supply to meet its energy needs.
- Conditions
- Aneurysm, AVM, Dural Arteriovenous Fistula, Glioma
- Trial name
- LSCI-NSURG (NCT05028400)
- Testing
- Laser speckle contrast imaging (LSCI)
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Contrast Echocardiography Imaging
Contrast Specific Echocardiogram Versus Left Ventricular Opacification (LVO) Imaging Settings
This study compares "contrast specific imaging setting" images with "left ventricular opacification (LVO)" images taken on the same group of patients at different points in time, to see if one is more effective at assessing the…
- Trial name
- ELVIS (NCT04286100)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- London North West Healthcare NHS Trust
Breast Cancer
The C-MERIT Screening Cohort: Contrast-enhanced Mammography for Breast Cancer Screening and Risk Assessment in Women With Dense Breasts
To learn whether a new imaging technology, Contrast-Enhanced Mammography (CEM), compared to standard mammography, can better detect breast cancers in women with dense breasts
- Trial name
- NCT05667532
- Testing
- Contrast Enhanced Mammography
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- M.D. Anderson Cancer Center
HCC - Hepatocellular Carcinoma
Comparison of Gd-EOB-DTPA-enhanced MRI and Contrast-enhanced Ultrasound for Measuring Tumor Size of Solitary Hepatocellular Carcinoma ≤ 5cm:A Retrospective Study
Knowing the tumor size before operation is of great significance to the choice of treatment methods of surgeons and the prognosis of patients.
- Trial name
- NCT06437457
- Testing
- ceus
- Where
- China
- Volunteers
- 194 people
- Sponsor
- Anhui Medical University
Patent Foramen Ovale, Cryptogenic Stroke
Long-term Outcomes After Percutaneous Patent Foramen Ovale Closure (Severance PFO Registry)
Patent foramen ovale (PFO) is a congenital interatrial communication present in about one quarter of the general population and is recognized as a major cause of cryptogenic stroke.
- Conditions
- Patent Foramen Ovale, Cryptogenic Stroke, Transient Ischemic Attack Due to Embolism, Atrial Fibrillation
- Trial name
- NCT07724171
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Yonsei University
Osteoarthritis, Obesity
Multi-parametric Imaging of the Knee in Obese Patients With Knee Osteoarthritis; Weight Loss
This is a substudy to a randomised trial investigating the effect of liraglutide on body weight and pain in overweight or obese patients with knee osteoarthritis (NCT02905864).
- Trial name
- IM-LOSEIT-I (NCT02928471)
- Testing
- Intensive dietary intervention
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Henrik Gudbergsen
Gallbladder Polyps or Masses Greater Than 8-10 mm in Size
Diagnostic Value of Endoscopic Ultrasound Elastography and Contrast Enhanced Endoscopic Ultrasound for Differential Diagnosis of Gallbladder Polyp
Gallbladder polyps are often detected incidentally by ultrasonography. The most of gallbladder polyps are non-neoplastic such as cholesterol polyps and do not need further treatments.
- Trial name
- NCT04416763
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Breast Cancer, Breast Cancer - Infiltrating Ductal Carcinoma
Percutaneous Cryoablation for the Treatment of Breast Cancer
The goal of this clinical trial is to study cryoablation as a treatment for selected adults with localized breast cancer. Cryoablation uses very low temperatures to destroy the tumor through thin needles placed through the skin…
- Trial name
- CRYSTAL (NCT07775014)
- Testing
- Ultrasound-Guided Percutaneous Cryoablation
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Ospedale Cottolengo
Contrast Induced Nephropathy
COmbined N-acetylcysteine and Bicarbonate in PCI To Reduce Adverse Side Effect of contrasT
This is a randomised controlled trial to investigate the efficacy of preventive regimen of hydration with high dose oral N-acetylcysteine and intravenous sodium bicarbonate pretreatment in patients with stable advanced renal…
- Trial name
- CONTRAST (NCT00497328)
- Testing
- N-acetylcysteine, Sodium Bicarbonate
- Where
- Singapore
- Volunteers
- 477 people
- Sponsor
- National University Hospital, Singapore
Coronary Artery Disease
Effects Contrast on Platelet Activity, Thrombosis and Fibrinolysis in Patients Undergoing Coronary Angiography
The aim of this study is to determine how two different types of iodinated contrast media (CM) agents, low-osmolar ionic ioxaglate and iso-osmolar non-ionic iodixanol, affect specific markers of thrombogenesis and platelet…
- Trial name
- NCT01848899
- Testing
- Iodixanol, Ioxaglate, Bivalirudin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Contrast Enhancement in Magnetic Resonance Imaging, Central Nervous System Pathology
A Study to Compare How Well Gadoquatrane Works and Its Safety With an Already Available Contrast Agent for MRI in People With Known or Suspected Brain or Spinal Cord-related Problems
Researchers are looking for a better way to help people with known or suspected brain or spinal cord-related problems scheduled for a "contrast-enhanced" Magnetic Resonance Imaging (MRI).
- Trial name
- Quanti CNS (NCT05915702)
- Testing
- Gadoquatrane (BAY1747846), Gadobutrol, Gadoterate meglumine
- Where
- 78 sites in United States, Argentina and 13 more
- Volunteers
- 321 people
- Sponsor
- Bayer
Trauma
Evaluation of Usefulness of Contrast Enhanced MRI in Evaluation of Spine Trauma: Prospective Study
Non-contrast MRI with T2 fat suppression has been a useful imaging modality in evaluation spinal trauma. However, the role of contrast enhancement has not investigated in patients with spinal trauma.
- Trial name
- NCT01880944
- Testing
- NC-MRI, CE-MRI
- Where
- 2 sites in South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Bundang Hospital
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