Clinical trials: Contrast Agent
Peripheral Arterial Disease, Intermittent Claudication
Non-Contrast Enhanced Peripheral Magnetic Resonance Angiography
To systematically develop, test, and refine peripheral vascular electrocardiography-gated fast spin echo magnetic resonance imaging for the accurate diagnosis of peripheral arterial disease without gadolinium contrast.
- Conditions
- Peripheral Arterial Disease, Intermittent Claudication, Peripheral Vascular Disease
- Trial name
- NCT02823444
- Testing
- Magnetic Resonance Angiography
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Utah
Acute ST Segment Elevation Myocardial Infarction
Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention
The aim of this study is to evaluate the effects of N-acetyl cysteine on major cardiac and cerebral events in patients undergoing primary percutaneous coronary intervention who have moderate to high risk for contrast induced…
- Trial name
- EASE-PRM-PCI (NCT01878344)
- Testing
- NAC, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Suleyman Demirel University
Contrast Induced Nephropathy, Metabolic Syndrome
Metabolic Syndrome and Contrast Induced Nephropathy
Prevention of contrast induced nephropathy after interventional cardiologic procedures deserves close interest because of its association with prolonged hospitalization, increased cost and increased in hospital and long term…
- Trial name
- NCT02192372
- Where
- Turkey (Türkiye)
- Volunteers
- 599 people
- Sponsor
- Ankara University
Crohn Disease (CD), Intestine Ultrasonography
Use of Water Ingestion in Small Intestine Ultrasound
Small Intestine Contrast Ultrasonography (SICUS) is an ultrasound-based method that explores bowel loops, and is able to identify wall thickness, intestinal motility, bowel wall vascularity and complications such as stenosis or…
- Trial name
- NCT07079007
- Testing
- Water
- Where
- Australia
- Volunteers
- 55 people
- Sponsor
- Austin Health
Carcinoma, Hepatocellular
Dynamic Contrast Enhanced HCC SABR Liver Study
The high dose per fraction (>10Gy/fraction) used in Stereotactic Ablative Body Radiotherapy (SABR) has been shown to be more effective at local tumor control than treatments employing more conventional dose fractions.
- Trial name
- NCT02847767
- Testing
- Perfusion Imaging
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- British Columbia Cancer Agency
Myocardial Infarction
Reproducibility of Magnetic Resonance Myocardial Salvage Index
The myocardial salvage assessed by using multimodal cardiac magnetic resonance imaging is a rather new technique which can be used as a surrogate endpoint to reduce the sample size in studies comparing different reperfusion…
- Trial name
- NCT00794300
- Testing
- second magnetic resonance imaging scan
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- University of Leipzig
Heart Disease
Evaluation of Safety and Efficacy of Lumason in Pediatric Echocardiography
Safety and Efficacy Study in pediatric subjects aged 9 to 17 years of age with suboptimal LV EBD on non-contrast 2D echocardiography.
- Trial name
- NCT02282163
- Testing
- sulphur hexafluoride lipid-type A microspheres
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Bracco Diagnostics, Inc
Clear Cell Renal Cell Carcinoma, Prognostic Cancer Model
Contrast-enhanced CT-based Deep Learning Model for Preoperative Prediction of Disease-free Survival (DFS) in Localized Clear Cell Renal Cell Carcinoma (ccRCC)
This study aims to preoperatively predict DFS of patients with localised ccRCC using a deep learning prognostic model based on enhanced contrast CT images, validate it's predictive ability in multicentre data and compare it's…
- Conditions
- Clear Cell Renal Cell Carcinoma, Prognostic Cancer Model, Recurrent Renal Cell Cancer
- Trial name
- NCT06088134
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Mingzhao Xiao
Small Bowel Adhesion, Small Bowel Obstruction
Low-osmolar Water Soluble Contrast Agent in Management of Adhesive Small Bowel Obstruction
Adhesive small bowel obstruction (ASBO) is a condition that is commonly found in patients with history of abdominal surgery. The management for such condition can be controversial.
- Trial name
- NCT06140173
- Testing
- Low osmolar contrast, Sterile water
- Volunteers
- 66 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Non STEMI, Unstable Angina
Safety and Efficacy of CMX-2043 for Protection of the Heart and Kidneys in Subjects Undergoing Coronary Angiography
The objective of this study is to evaluate CMX-2043 for prevention of renal and cardiac injury associated with coronary angiography in patients with acute coronary syndrome (ACS), but excluding ST-elevation myocardial infarction…
- Trial name
- CARIN (NCT02103959)
- Testing
- CMX-2043
- Volunteers
- 361 people
- Sponsor
- Ischemix, LLC
Bladder Cancer, Staging
Bladder Cancer Staging and Prediction of New Adjuvant Chemotherapy Efficacy Based on Deep Learning and Transfer Learning in Ultrasound-Magnetic Resonance-Pathology Multimodal Multiscale
Bladder cancer is the most common malignant tumor of the urinary system. The presence or absence of muscle invasion in early bladder cancer is an independent prognostic factor.
- Conditions
- Bladder Cancer, Staging, Deep Learning, Neoadjuvant Chemotherapy
- Trial name
- MICS-BC (NCT07051083)
- Testing
- Risk Stratification
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Malignant Solid Tumor, Lymphomas
Safety and Pharmacokinetic Study of RRx-001 in Cancer Subjects
The purpose of this study is to evaluate the safety and pharmacokinetic profile of RRx-001 for injection in subjects with advanced solid tumors or lymphomas for which there are no currently accepted curative therapies.
- Trial name
- DINAMIC (NCT01359982)
- Testing
- RRx-001
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- EpicentRx, Inc.
Coronary Artery Disease, Chronic Kidney Diseases
IVUS Guided PCI for CKD to Reduce CI-AKI
Patients with Chronic kidney disease are most vulnerable to contrast induced nephropathy after Percutaneous coronary intervention, intravascular ultrasound guidance can be used to safely guide the procedure to reduce the contrast…
- Trial name
- IVUS-CKD (NCT05913362)
- Testing
- IVUS based ultralow contrast PCI
- Where
- 2 sites in China
- Volunteers
- 320 people
- Sponsor
- Jilin University
Prostate Cancer
Non-contrast MR Imaging for Whole Body Cancer Detection and Characterization
This study aims to learn how to improve MRIs (Magnetic Resonance Imaging) that do not require the patient to be injected with a contrast dye.
- Trial name
- NCT03440554
- Testing
- Whole Body Non-Contrast MRI
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Diego
Fibrosis, Kidney Failure
Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Moderate Renal Insufficiency After the Administration of Magnevist
Assess potential risk for NSF in subjects with renal impairment (moderate) post magnevist injection. Subjects will be screened within 48 hours of previously scheduled MRI, those meeting the enrollment criteria will be enrolled…
- Conditions
- Fibrosis, Kidney Failure, Renal Insufficiency
- Trial name
- NCT00744939
- Testing
- Gadopentetate dimeglumine (Magnevist, BAY86-4882)
- Where
- 26 sites in United States
- Volunteers
- 168 people
- Sponsor
- Bayer
Nephrogenic Fibrosing Dermopathy
Safety Evaluation of Linear and Macrocyclic Gadolinium Based Contrast Agents for Patients With Mild to Moderate Renal Insufficiency Undergoing Enhanced Magnetic Resonance Imaging
The purpose of this study is to evaluate the safety of linear and macrocyclic gadolinium-based contrast agents for patients with mild to moderate renal insufficiency.
- Trial name
- NCT04776187
- Testing
- Gadodiamide, Gadoteric Acid Meglumine Salt
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The Central Hospital of Lishui City
Liver Neoplasms
Contrast Enhanced Ultrasound to Evaluate Response to Chemoembolization in Patients With Liver Tumors
This phase II trial evaluates the diagnostic performance of contrast-enhanced ultrasound (CEUS) for assessing treatment response in patients undergoing transarterial chemoembolization (TACE) for liver tumors.
- Trial name
- NCT06261814
- Testing
- Sulfur Hexafluoride Lipid Microspheres, Contrast-Enhanced Ultrasound, Transarterial Chemoembolization
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- john eisenbrey
Acute Kidney Injury (Nontraumatic), Contrast-induced Nephropathy
Data on the Prevention of Complications of Prophylactic Intravenous Hydration in Patients With eGFR < 30
At Maastricht University Medical Centre (Maastricht UMC+) a specialised unit was established where a dual screening process including both renal and cardiac parameters is used to minimize the risk of contrast-induced acute kidney…
- Trial name
- CVP (NCT04592406)
- Testing
- CVP screening
- Where
- Netherlands
- Volunteers
- 443 people
- Sponsor
- Maastricht University Medical Center
Cardiovascular Disease
A Prospective, Phase IV, Surveillance Registry Study to Evaluate the Safety of DEFINITY® in Clinical Practice
The purpose of this registry study is to gather safety information on the current clinical use of and the safety of DEFINITY®
- Trial name
- NCT00625365
- Testing
- DEFINITY®
- Where
- 16 sites in United States
- Volunteers
- 1,060 people
- Sponsor
- Lantheus Medical Imaging
Healthy Volunteers, Patients
Magnetic Resonance Imaging (MRI) Ofl Volunteers
Magnetic resonance is an imaging technique that uses magnetic fields and radio waves to create images of the body. The technology used in magnetic resonance imaging continues to improve.
- Trial name
- NCT00001711
- Testing
- MRI
- Where
- United States
- Volunteers
- 1,229 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
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