Clinical trials: Contrast Agent
Diabetes Mellitus, Coronary Artery Disease
Metformin in Diabetic Patients Undergoing Coronary Angiography
The present study aims to evaluate the strict application of the 2018 European Society of Cardiology guidelines on myocardial revascularization, that recommends to check renal function if patients have taken metformin immediately…
- Conditions
- Diabetes Mellitus, Coronary Artery Disease, Lactic Acidosis With Diabetes Mellitus, Contrast-induced Nephropathy
- Trial name
- NO-STOP (NCT04766008)
- Testing
- Metformin
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Humanitas Hospital, Italy
Metastasis to Liver, Colorectal Cancer
Comparison of Image Quality Between "Double Low Dose" Liver CT and Standard Liver CT
In patients with malignancies, contrast-enhanced abdominal CT (hereafter abdominal CT) plays an important role in detecting carcinoma recurrence and assessing treatment response.
- Trial name
- NCT05790590
- Testing
- Double low dose CT, Standard dose CT
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Seoul National University Hospital
Heart; Functional Disturbance
Hand Injected Ventriculography vs. Power Injected Left Ventriculography
The purpose of the study is to directly compare two methods of evaluating heart function at the time of your angiogram. In both methods contrast dye is injected into the main heart chamber during the angiogram while x-ray images…
- Trial name
- NCT01310517
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Loma Linda University
Patient and Staff Radiation Exposure During Aorto-iliac Endovascular Revascularization
Patient and Staff Safety During Aorto-iliac Revascularization Procedures Under Automated Fusion Imaging Guidance With Controls
Endovascular revascularization has revolutionized the field of vascular surgery and has become the first-choice treatment for peripheral arteries occlusive disease.
- Trial name
- CYDAR ILIAC (NCT03713450)
- Testing
- Control with imaging guidance, Control without imaging guidance
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Nantes University Hospital
Breast Cancer Diagnosis, Breast Cancer Detection
Second-Look Ultrasound Post Contrast-Enhanced Mammography for Additional Lesions Characterization
This study investigates the utility of second-look ultrasound (US) following contrast-enhanced mammography (CEM) to characterize additional lesions detected during routine breast imaging.
- Trial name
- NCT06846814
- Testing
- CEM protocol
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Graziella di Grezia
Cardiac Disease
Validation of Multi-contrast, High-resolution Cardiac Magnetic Resonance Imaging
Cardiovascular disease (CVD) causes at least 1.8 million European deaths annually, exceeding fatalities from cancer, chronic respiratory disease, and diabetes.
- Trial name
- CARDIO-IRM (NCT05877755)
- Testing
- Cardiac MRI acquisition
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Complex Renal Cyst
Contrast-enhanced Ultrasound for the Evaluation of Complex Renal Cysts
Complex renal cysts are often incidentally detected on imaging. The differential diagnosis of the complex renal cyst includes various benign cystic lesions, which are based on the Bosniak classification scheme.
- Trial name
- NCT01353521
- Testing
- Contrast-enhanced ultrasound
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Coronary Artery Disease, Angina, Unstable
Contrast-associated Acute Kidney Injury in Patients With Different Types of Coronary Artery Disease
The goal of the study is to assess the prevalence of contrast-associated acute kidney injury in patients with stable coronary artery disease, ST-elevation myocardial infarction and unstable angina/NSTEMI, assess the risk factors…
- Conditions
- Coronary Artery Disease, Angina, Unstable, Angina, Stable, STEMI - ST Elevation Myocardial Infarction
- Trial name
- NCT04163484
- Testing
- Iodinated contrast
- Where
- Russia
- Volunteers
- 156 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Breast Cancer
Red Clover and Lifestyle Changes to Contrast Menopausal Symptoms in Premenopausal Breast Cancer Patients Given Tamoxifen
A prospective double-blind randomized trial of red clover extract (Promensil) vs placebo in surgically-treated premenopausal women with estrogen receptor-positive breast cancer taking tamoxifen
- Trial name
- NCT03844685
- Testing
- Promensil
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Pancreas Neoplasm
Multicentered Prospective Randomized Controlled Trial For Solid Pancreatic Lesions
Endoscopic ultrasound (EUS) is an indispensable tool for tissue acquisition for pancreatic lesions. Fine needle aspiration (FNA) is once considered as the first line diagnostic method especially when rapid on-site evaluation…
- Trial name
- NCT04841616
- Testing
- Endoscopic Ultrasound -Guided Fine Needle Biopsy, Contrast-Enhanced Harmonic Endoscopic Ultrasound
- Where
- Hong Kong
- Volunteers
- 128 people
- Sponsor
- Chinese University of Hong Kong
Stenosis
Application of Contrast Enhance Ultrasound to Evaluate Hemodynamics Change in MCA With Moderate to Severe Stenosis
Objective: To monitor and evaluate the change of intracranial hemodynamics and MCA stenosis after 24-week atorvastatin treatment using CEUS, CTA and DSA.
- Trial name
- NCT01617538
- Testing
- atorvastatin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Brain Metastases, Adult
Multi -paramEtric Imaging to Assess Treatment REsponse After Stereotactic Radiosurgery of Brain Metastases
After stereotactic radiosurgery (SRS) of brain metastases, patients undergo a standard brain magnetic resonance imaging (MRI) to assess treatment response 12 weeks after completion of treatment.
- Trial name
- METRE (NCT04626206)
- Volunteers
- 12 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Breast Cancer, Locally Advanced Breast Cancer
Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer
The purpose of this study is to compare a special type of mammogram that uses a contrast agent called contrast-enhanced digital mammography with contrast-enhanced digital breast tomosynthesis (CEDM+CEDBT), with breast magnetic…
- Conditions
- Breast Cancer, Locally Advanced Breast Cancer, Neoadjuvant Chemotherapy, HER2-positive Breast Cancer
- Trial name
- NCT06220214
- Testing
- CEDM, CEDBT, Omnipaque 350mgI/mL Solution for Injection
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Alison Stopeck
Coronary Artery Disease
Safety and Efficacy Study of Dual-axis Rotational Versus Standard Coronary Angiography
The purpose of this study is to assess the clinical safety and efficacy of dual-axis rotational coronary angiography (DARCA) in the diagnosis of coronary artery disease by directly comparing it to standard coronary angiography…
- Trial name
- NCT01625533
- Testing
- Standard Coronary Angiography, Dual-axis Rotational Coronary Angiography
- Where
- China
- Volunteers
- 576 people
- Sponsor
- General Hospital of Chinese Armed Police Forces
Ventricular Tachycardia, Ischemic Cardiomyopathy
Contrast ICE for Myocardial Scar in VT Ablations
There is a high correlation between scar areas identified by contrast-enhanced ICE and scar areas identified by conventional electroanatomic mapping.
- Trial name
- NCT03212326
- Testing
- Perflutren Lipid Microsphere Intravenous Suspension [DEFINITY]
- Volunteers
- 24 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Kidney Disease, Pulmonary Embolism
Safety of Low Dose IV Contrast CT Scanning in Chronic Kidney Disease
The purpose of this study is to show that the use of low volume iso-osmolar non-ionic radio contrast medium (30 cc) in a thoracic CT Scanning procedure in a selected group of patients with chronic kidney disease (CKD) will avoid…
- Conditions
- Chronic Kidney Disease, Pulmonary Embolism, Renal Artery Stenosis, Pulmonary Cancer
- Trial name
- NCT02476526
- Testing
- Low Volume iso-osmolar non-ionic radio contrast medium, Acetylcysteine Inhalation, Sodium Bicarbonate Solution
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Ovarian Cancer, Adnexal Lesion
Contrast-enhanced Ultrasound Evaluation of Indeterminate Ovarian Lesions: Prospective Multicenter Study
The goal of this clinical trial is to learn how well contrast-enhanced ultrasound (CEUS) can diagnose ovarian cancer in patients with indeterminate or suspicious ovarian/adnexal lesions identified on routine ultrasound or MRI.
- Trial name
- NCT07849543
- Testing
- Contrast-Enhanced Ultrasound (CEUS)
- Volunteers
- 190 people
- Sponsor
- Thomas Jefferson University
Breast Cancer, Postsurgical Acquired Absence of Organ
Non-contrast Magnetic Resonance Angiography in Deep Inferior Epigastric Perforator Flap Breast Reconstruction Planning
The aim of this study is to evaluate the efficacy and safety of contrast-free magnetic resonance angiography (MRA) for deep inferior epigastric perforator flap planning.
- Trial name
- NCT06061835
- Testing
- Non-contrast MRA in preoperative perforator vessels mapping for deep inferior epigastric perforator (DIEP) flap breast reconstruction planning., CTA with iodine contrast in preoperative perforator vessels mapping for deep inferior epigastric perforator (DIEP) flap breast reconstruction planning.
- Where
- 2 sites in Russia
- Volunteers
- 135 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Carcinoma, Renal Cell, Diagnostic Imaging
Deep Learning for Automated Discrimination Between Stage T1-T2 and T3 Renal Cell Carcinoma on Contrast-Enhanced CT
This study aims to develop and validate a contrast-enhanced CT-based deep-learning model for automatic and accurate preoperative discrimination between T1-T2 and T3 renal cell carcinoma.
- Conditions
- Carcinoma, Renal Cell, Diagnostic Imaging, Pathology, Deep Learning
- Trial name
- NCT07166445
- Testing
- None intervention
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Cystic Fibrosis
Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis
Cystic fibrosis (CF) results in the thickening of mucus in the lungs and other organs due to dysfunction of a transmembrane conductance protein.
- Trial name
- NCT04467957
- Testing
- Initiation of CFTR Modulator, Hyperpolarized Xenon 129
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
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