Clinical trials: Contrast Agent
Acute Kidney Injury, Contrast Media Toxicity
Curcuminoids and Contrast-induced Acute Kidney Injury
The objective of this study was to evaluate the role of curcuminoids in the prevention of CI-AKI in CKD patients.The result of the study was prophylactic administration with curcuminoids in addition to standard treatment reduce…
- Conditions
- Acute Kidney Injury, Contrast Media Toxicity, Curcuminoid, Chronic Kidney Diseases
- Trial name
- NCT04890704
- Testing
- Curcuminoid
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Acute ST Segment Elevation Myocardial Infarction
Predictive Value of CHA2DS2VASC Score for Contrast-induced Nephropathy After Primary Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction Patients
Contrast induced acute kidney injury has commonly been referred to as contrast induced nephropathy (CIN) defined as an increase in serum creatinine ≥25% or ≥0.5 mg/dl from baseline within 48-72 hours with peak incidence 2-5 days…
- Trial name
- NCT04730778
- Testing
- serum creatinine and estimated glomerular filtration rate, on daily basis
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Skin Diseases, Healthy Skin
An Observational Study to Assess Objective Skin Pigmentation Variation.
Accurate assessment of skin pigmentation is essential in dermatology for properly diagnosing and managing a wide range of skin conditions.
- Trial name
- SKIN-IMAGING (NCT07091604)
- Where
- Netherlands
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Aortic Dissection
Hemodynamic Changes in the Aorta After Endovascular Treatment of the Aortic Dissection
Aortic dissection (AD) is a serious pathology affecting one person for 300 000 habitants per year. In case of complicated AD on the descending aorta, it is necessary to perform an endovascular surgery in association with medical…
- Trial name
- 4DAo (NCT03669055)
- Testing
- Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Hospices Civils de Lyon
Acute Ischemic Stroke
CHinese ischEmic Stroke Beyond 4.5 Hours With TeNecteplase Under Optimized Non-Contrast CT Selection
The CHESTNUT trial is a multicenter, open-label, blinded-endpoint, randomized, controlled, phase 3 trial. The primary objective of this study is to explore the efficacy and safety of the dose of 0.25 mg/kg tenecteplase (TNK) in…
- Trial name
- CHESTNUT (NCT06994975)
- Testing
- 0.25mg/kg TNK, Standard medical treatment
- Where
- 2 sites in China
- Volunteers
- 890 people
- Sponsor
- Huashan Hospital
Emergent Coronary Procedure
Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate Bolus Injection
This study is to investigate the effect of Sodium Bicarbonate bolus injection in patients undergoing an emergent coronary procedure for prevention of contrast-induced nephropathy.
- Trial name
- NCT00700375
- Testing
- Sodium bicarbonate, Sodium Chloride
- Where
- Japan
- Volunteers
- 59 people
- Sponsor
- Osaka General Medical Center
Contrast Induced Nephropathy
Patients With Renal Impairment Undergoing CT
The purpose of the study is to compare the incidence of contrast induced nephrotoxicity following the administration of Isovue or Visipaque in patients with mild to moderate renal impairment who undergo a clinically indicated IV…
- Trial name
- NCT00292487
- Testing
- Iopamidol 370 mgI/mL
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Bracco Diagnostics, Inc
Breast Cancer
Contrast-Enhanced MRI for the Characterization of Ductal Carcinoma in Situ (DCIS)
*REFERRALS TO THIS TRIAL MUST BE THROUGH BREAST CARE CLINICIANS ONLY* RATIONALE: Diagnostic procedures, such as contrast-enhanced MRI, may help find and diagnose ductal carcinoma in situ.
- Trial name
- NCT00804128
- Testing
- Magnetic Resonance Imaging (MRI), Gadavist
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of California, San Francisco
Lymph Node Metastases, Breast Cancer
A Prospective Validation Cohort Study of a Prediction System on nSLN Metastasis in Early Breast Cancer
In the previous study, the investigator established a predictive model for non-sentinel lymph node involvement in early breast cancer (cT1-2cN0, 1-2 SLNs involvement).
- Conditions
- Lymph Node Metastases, Breast Cancer, Predictive Cancer Model
- Trial name
- NCT03280134
- Testing
- axillary lymph node dissection (ALND)
- Where
- China
- Volunteers
- 388 people
- Sponsor
- Zhejiang Cancer Hospital
Myelomeningocele, Neurogenic Bladder
Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies
The investigators will assess the feasibility of replacing fluoroscopy/iodinated contrast with ultrasound/sulfur hexafluoride lipid-type A microspheres during routine urodynamic studies.
- Conditions
- Myelomeningocele, Neurogenic Bladder, Tethered Cord Syndrome, Bladder, Neurogenic
- Trial name
- NCT04738539
- Testing
- Contrast Enhanced Voiding Urosonography with Urodynamic Testing, Urodynamic Testing
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Lenses, Intraocular, Glistenings
Impact of Glistenings in AcrySof Intraocular Lenses on Visual Quality
This study will assess the impact of IOL glistenings on visual quality and function in patients implanted with a single-piece AcrySof intraocular lens (IOL) that exhibits glistening formations.
- Conditions
- Lenses, Intraocular, Glistenings, Visual Quality
- Trial name
- NCT01202981
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Utah
Kidney; Obstruction, Renal Obstruction
Contrast Enhanced Ultrasound for Renal Obstruction
This research is studying Definity ultrasound contrast agent, which is already approved by the Food and Drug Administration (FDA) for the ultrasound evaluation of the liver and heart.
- Trial name
- NCT05090800
- Testing
- Definity contrast during ultrasound
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Michigan
Appendicitis Acute
Low-dose Contrast Media for Low-kVp Abdomen CT
The purpose of this clinical study is to test the performance of low radiation dose abdominal CT combined with low dose contrast media for the diagnosis of acute appendicitis in young patients.
- Trial name
- NCT05878665
- Testing
- Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Bohyun Kim
Malaria, Pyelonephritis
Contrast-Enhanced US of Spleen, Liver and Kidney
To evaluate the changes in the microcirculation of the liver, kidney and spleen during acute infection in patients with malaria (cohorts 1 and 3) and other infectious diseases such as acute pyelonephritis at day 0 (within 8 hours…
- Conditions
- Malaria, Pyelonephritis, Bacterial Infections
- Trial name
- NCT00190281
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Right-To-Left Shunt
Comparing the Safety and Efficacy of ASI-02 to Agitated Saline for Suspected Right-to-left Shunt
This is a phase 3, multicenter, open-label, blinded, crossover trial in which each participant will undergo a randomized sequence of ASI-02 and agitated saline standard of care (SoC) via a saline contrast transthoracic…
- Trial name
- ENHANCE (NCT06938347)
- Testing
- Agitated Saline SoC, ASI-02
- Where
- 8 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- Agitated Solutions, Inc.
Coronary Artery Disease
A Low-dose Radiation and Contrast Agent Exposure Protocol for Coronary CTA in Diabetic Patients
To assess diagnostic accuracy,image quality and renal safety of a double low-dose coronary CTA protocol at coronary artery evaluation in patients with diabetes by using invasive coronary angiography(ICA) as the reference method…
- Trial name
- NCT04342455
- Testing
- double-low scanning
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Acute Kidney Injury
Double-Blind Placebo-Controlled CIN Trial
This double-blinded placebo-controlled study will examine the incidence and significance of contrast-induced acute kidney injury following IV iodine-based contrast material administration in subjects with stage IIIB or stage IV…
- Trial name
- NCT02467075
- Testing
- Iopamidol 300 (Contrast)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Michigan
Hepatocellular Carcinoma, Contrast-enhanced Ultrasound
Clinical Decision Biological Biomarker and Prognosis Prediction of Hepatocellular Carcinoma by Deep Learning
Developing a deep learning model based on contrast-enhanced ultrasound (CEUS) to predict the prognosis of hepatocellular carcinoma (HCC) and aid choose operation decisions
- Conditions
- Hepatocellular Carcinoma, Contrast-enhanced Ultrasound, Prognosis, Surgery
- Trial name
- NCT05257694
- Testing
- Surgery, Ablation (Microwave ablation or Radiofrequency ablation)
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Ping Liang
Liver Cancer
Contrast-Enhanced CT and MRI in Diagnosing and Staging Liver Cancer Using UNOS Policy
RATIONALE: Diagnostic procedures, such as contrast-enhanced CT scan and contrast-enhanced MRI, may help find liver cancer and find out how far the disease has spread.
- Trial name
- ACRIN6690 (NCT01082224)
- Testing
- iodinated contrast dye, motexafin gadolinium, Eovist-enhanced MRI
- Where
- 9 sites in United States
- Volunteers
- 440 people
- Sponsor
- American College of Radiology Imaging Network
Acute Kidney Failure
Ioxaglate Versus Iodixanol for the Prevention of Contrast-induced Nephropathy in High-risk Patients (IDPC Trial)
Contrast media-induced nephropathy following diagnostic and therapeutic cardiac catheterization.
- Trial name
- IDPC (NCT02991742)
- Testing
- contrast media
- Volunteers
- 2,262 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
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