Clinical trials: Contrast Induced Acute Kidney Injury
Acute Ischemic Stroke, Contrast-induced Nephropathy
Serum Electrolytes and Contrast-Induced Nephropathy in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment
This study aims to evaluate the relationship between serum electrolyte levels and the development of contrast-induced acute kidney injury (CI-AKI) in patients with acute ischemic stroke undergoing endovascular therapy (EVT).
- Conditions
- Acute Ischemic Stroke, Contrast-induced Nephropathy, Acute Kidney Injury
- Trial name
- NCT07546448
- Testing
- No intervention (observational cohort study)
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Contrast-induced Acute Kidney Injury
Remote Ischemic Preconditioning to Prevent Contrast-Induced Kidney Injury in Diabetic Patients (PRINCES)
This study investigates whether remote ischemic preconditioning (RIPC)-a non-invasive technique involving brief cycles of blood flow restriction to the arm-can prevent contrast-induced nephropathy (CIN) in diabetic patients…
- Trial name
- PRINCES (NCT07179874)
- Testing
- Remote Ischemic Preconditioning
- Volunteers
- 71 people
- Sponsor
- Universidad de Murcia
Acute Myocardial Infarction, Acute Kidney Injury
Sodium Bicarbonate and N-Acetylcysteine for Nephroprotection in Acute Myocardial Infarction
Contrast-induced nephropathy (CIN) represents a potential complication of diagnostic and therapeutic procedures in interventional cardiology, especially in the acute setting of primary PCI.
- Trial name
- BINARIO (NCT01218178)
- Testing
- Sodium bicarbonate plus NAC, Saline hydration plus NAC
- Where
- Italy
- Volunteers
- 520 people
- Sponsor
- Catholic University of the Sacred Heart
Acute Kidney Injury
Double-Blind Placebo-Controlled CIN Trial
This double-blinded placebo-controlled study will examine the incidence and significance of contrast-induced acute kidney injury following IV iodine-based contrast material administration in subjects with stage IIIB or stage IV…
- Trial name
- NCT02467075
- Testing
- Iopamidol 300 (Contrast)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Michigan
Coronary Artery Disease, Chronic Kidney Disease
Hydration Guided by Remote Dielectric Sensing (ReDS) System for Preventing Acute Kidney Injury in Elderly Patients With Renal Insufficiency for Coronary Angiography and Intervention
Explore the effectiveness and safety of tailored hydration guided by lung water index monitor system for prevention of acute kidney injury after percutaneous coronary intervention for elderly patients with renal insufficiency.
- Conditions
- Coronary Artery Disease, Chronic Kidney Disease, Elderly
- Trial name
- HISTORY (NCT07394959)
- Testing
- Tailored hydration guided by ReDS system
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Chinese PLA General Hospital
Aortic Valve Disease, Chronic Kidney Disease
Preventing contrAst Induced Nephropathy After TranscathEter Aortic Valve Replacement
Chronic kidney disease (CKD) and (subsequent) acute kidney injury are frequent in patients undergoing transcatheter aortic valve implantation (TAVI).
- Conditions
- Aortic Valve Disease, Chronic Kidney Disease, Contrast Induced Nephropathy, Acute Kidney Injury
- Trial name
- PANTER (NCT03121053)
- Testing
- sodium bicarbonate, hypotone saline
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- St. Antonius Hospital
Cardio-Renal Syndrome, Coronary Angiography
Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention
As a single center, retrospective observation study in Guangdong Institute of Cardiovascular Diseases, this study included the main study population of patients who underwent coronary angiography and / or coronary intervention…
- Conditions
- Cardio-Renal Syndrome, Coronary Angiography, Coronary Artery Disease, Kidney Diseases
- Trial name
- NCT04407936
- Where
- China
- Volunteers
- 88,938 people
- Sponsor
- Guangdong Provincial People's Hospital
Contrast Induced Nephropathy
Erythropoietin in Radiocontrast Induced Nephropathy (ERIN) Trial
Full Title: A Randomized Controlled Trial of Procrit for the Prevention of Acute Renal Failure in Patients Receiving Intravenous Contrast Primary Objective: To evaluate the efficacy of a one-time dose of intravenous…
- Trial name
- ERIN (NCT00476619)
- Testing
- erythropoeitin
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Brigham and Women's Hospital
Acute Kidney Injury
Oral Salt and Water to Prevent Contrast Nephropathy
The purpose of this pilot trial is to determine the safety and feasibility of using oral salt and water loading compared to intravenous saline for the prevention of contrast-induced acute kidney injury in patients with chronic…
- Trial name
- NCT02084771
- Testing
- Intravenous Saline, Oral Salt and Water
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Contrast Induced Nephropathy, Acute Kidney Injury
A Maastricht Contrast-Induced Nephropathy Guidelines Study: CIN Prevention Guidelines: Appropriate & Cost-effective?
Contrast-induced nephropathy (CIN) is a side-effect of intravascular administration of iodinated contrast material. It is defined as an absolute (>44μmol/l) or relative (>25%) increase in serum creatinine from baseline values…
- Trial name
- AMACING (NCT02106234)
- Testing
- No prophylactic iv hydration
- Where
- Netherlands
- Volunteers
- 660 people
- Sponsor
- Maastricht University Medical Center
CIN
Risk Factors,PREvention and OutComes for CI-AKI in PatientS undErgoing PCI at Intensive Care Unit(PRECISE-ICU)
A retrospective, observational study included all consecutively critically ill patients undergoing percutaneous coronary intervention(PCI) at intensive care unit (ICU) in Fujian Provincial Hospital from January 1st 2012 to…
- Trial name
- PRECISE-ICU (NCT03791606)
- Where
- China
- Volunteers
- 755 people
- Sponsor
- Kaiyang Lin
Acute Kidney Injury
Efficacy and Safety of Deferiprone in Patients With Chronic Kidney Disease Undergoing a Cardiac Catheterization and Receiving Contrast Agent
This trial will evaluate whether treatment with CRMD001 (unique formulations of the iron chelator, Deferiprone) will reduce morbidity and mortality in subjects with Chronic Kidney Disease (CKD) and additional risk factors.
- Trial name
- NCT01391520
- Testing
- deferiprone
- Sponsor
- CorMedix Therapeutics
Contrast-Induced Acute Kidney Injury in ST-Segment Elevation Myocardial Infarction, Contrast Induced AKI
The Effect of Hydration on the Prevention of CI-AKI in STEMI Patients Undergoing Primary PCI (Hydro-AKI Trial)
The goal of this clinical trial is to determine whether a structured oral hydration regimen reduces the incidence of contrast-induced acute kidney injury (CI-AKI) in patients with ST-segment elevation myocardial infarction…
- Trial name
- Hydro-AKI (NCT07761754)
- Testing
- oral hydration protocol
- Volunteers
- 384 people
- Sponsor
- Assiut University
Kidney Injury, Contrast-induced Nephropathy
Early Diagnosis as Strategy in Reducing the Incidence of Contrast-induced Nephropathy
Renal damage due to contrast media (CM) administration is one of the main complications of cardiac intervention and is called contrast-induced nephropathy (CIN).
- Trial name
- NCT04225013
- Testing
- Early kidney damage biomarkers, Predisposition to kidney injury biomarkers
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- R. Laura Vicente Vicente
X-ray Contrast Media Adverse Reaction
Bioimpedance Analysis Guided Volume Expansion for the Prevention of Contrast Induced-acute Kidney Injury
Bioelectrical impedance analysis guided volume expansion for the prevention of contrast induced-acute kidney injury
- Trial name
- BELIEVE (NCT02449317)
- Testing
- Bioimpedance guided, standard hydration
- Volunteers
- 56 people
- Sponsor
- Mahidol University
Acute Kidney Injury
Tailored Hydration Based on Bioimpedance Analysis for Prevention of Contrast Induced Acute Kidney Injury
The aim of this study was to evaluate, in patients with "normal fluid status" assessed by the bio-impedance analysis, whether two different protocol of IV isotonic saline infusion are associated with different volume expansion…
- Trial name
- Hydra2 (NCT04215042)
- Testing
- sodium chloride infusion
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Ospedale Misericordia e Dolce
Acute Kidney Injury (Nontraumatic), Contrast-induced Nephropathy
Data on the Prevention of Complications of Prophylactic Intravenous Hydration in Patients With eGFR < 30
At Maastricht University Medical Centre (Maastricht UMC+) a specialised unit was established where a dual screening process including both renal and cardiac parameters is used to minimize the risk of contrast-induced acute kidney…
- Trial name
- CVP (NCT04592406)
- Testing
- CVP screening
- Where
- Netherlands
- Volunteers
- 443 people
- Sponsor
- Maastricht University Medical Center
Induced Acute Kidney Injury, High-risk Percutaneous Coronary Intervention
Protect Kidney Trial
This trial is a randomized, controlled, open-label, parallel study. Patients at high risk for contrast induced acute kidney injury (CI AKI) and planned high-risk percutaneous coronary intervention (PCI) will be randomized to…
- Trial name
- NCT04321148
- Testing
- standard of care PCI, Impella-protected PCI
- Where
- Germany
- Volunteers
- 224 people
- Sponsor
- Heinrich-Heine University, Duesseldorf