Clinical trials: Contrast Media
Contrast Enhancement in Magnetic Resonance Imaging, Healthy Volunteers
A Study to Learn More About the Safety and the Blood Level of BAY1747846 Given as Injection Into the Vein at Increasing Single Doses in Chinese Healthy Male Participants
The goal of this clinical study was to learn more about BAY1747846 compared to placebo when given as an injection into the vein in Chinese healthy male participants: the safety of BAY1747846 when given at increasing single doses…
- Trial name
- NCT06135181
- Testing
- Gadoquatrane (BAY1747846) 0.03 mmol Gd/kg, Gadoquatrane (BAY1747846) 0.1 mmol Gd/kg
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Melanoma
High-resolution Magnetic Resonance Imaging (MRI) Scans to Look for Spread of Melanoma to Nearby Lymph Nodes
The study is designed to see if a high-resolution MRI scan of lymph node areas near where a melanoma has been removed from the skin can pick up the spread of melanoma to those lymph nodes with a high degree of accuracy.
- Trial name
- NCT00463892
- Testing
- High-resolution contrast-enhanced MRI scan
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Redwood Regional Medical Group
Coronary Artery Disease (CAD), Renal Impairment
Renal Effects of Three Iodinated Contrast Media (CM) in Patients at Risk Undergoing Coronary Angiography
The study is to evaluate and compare the effects on kidney function of three iodinated contrast media (CM) in patients at risk of kidney damage evaluating serum creatinine (Scr) concentrations up to three days after CM…
- Conditions
- Coronary Artery Disease (CAD), Renal Impairment, Diabetes Mellitus
- Trial name
- NCT00335101
- Testing
- Iodixanol, Ioversol, Iopromide
- Where
- 2 sites in United States, Germany
- Sponsor
- GE Healthcare
Chronic Renal Insufficiency, Coronary Angiography
Contrast-medium Induced Nephrotoxicity in Patients Undergoing Coronary Angiography - Iodixanol Versus Iopromide
In the treatment of coronary heart disease which is the major cause of heart attack, direct mechanical treatment with catheters such as the coronary angiography, coronary balloon intervention and stenting intervention are the…
- Trial name
- NCT00823628
- Testing
- contrast agent (iopromide), contrast agent (iodixanol)
- Where
- South Korea
- Volunteers
- 420 people
- Sponsor
- Seoul National University Bundang Hospital
Renal Neoplasms, Renal Cyst
AI for Renal Tumors Using Non-Contrast CT
The goal of this observational study is to learn whether the artificial intelligence method can automatically identify and diagnose renal lesions using non-contrast CT or opportunistic screening.
- Trial name
- NCT07304492
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Fudan University
Breast Cancer
Feasibility of Blood Oxygenation Level-Dependent Contrast (BOLD) Breast MRI Induced by Breath- Holding
In this study, investigators intend to measure changes in BOLD contrast in the breast induced by breath-holding for subjects receiving radiation therapy to the breast.
- Trial name
- BOLD (NCT01898533)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Duke University
Thoracic Aortic Aneurysm
Thoracoabdominal Arortic CTA Study
The purpose of this study is to compare the contrast agents and imaging techniques used for thoracoabdominal aortic imaging in CT.
- Trial name
- NCT02291718
- Testing
- Isovue
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Duke University
Coronary Disease
Atorvastatin Effect on Contrast Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary Intervention
Investigate of the potential benefit of acute pretreatment with high dose atorvastatin (80 mg) in reduction of the incidence of CIN in diabetic patients indicated for elective coronary intervention.
- Trial name
- NCT04375787
- Testing
- Atorvastatin
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mohamed Abdelfatah
Breast Neoplasms, Artificial Intelligence (AI)
Non-Contrast Breast MRI Diagnosis and Risk Stratification Using DWI-Generated Synthetic Contrast Enhancement
This study is conducted under the ethics-approved project titled "Artificial Intelligence Solution for Simplifying the Diagnostic Workflow of Breast MRI''.The goal of this observational study is to develop an integrated breast…
- Conditions
- Breast Neoplasms, Artificial Intelligence (AI), Magnetic Resonance Imaging (MRI), Diffusion Magnetic Resonance Imaging
- Trial name
- NCT07598084
- Testing
- Non-contrast breast MRI diagnostic model
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Endometriosis, Sigmoid, Endometriosis, Rectum
Three-dimensional (3D) Rectal Water Contrast Transvaginal Ultrasonography Versus Computed Colonography in the Diagnosis of Rectosigmoid Endometriosis
Rectosigmoid involvement by endometriosis causes intestinal symptoms such as constipation, diarrhea, and dyschezia. A non-invasive diagnosis of bowel endometriosis is relevant to provide the patients information on the potential…
- Trial name
- NCT04295343
- Testing
- Three-dimensional (3D) rectal water contrast transvaginal ultrasonography, Computed colonography
- Where
- Italy
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ospedale Policlinico San Martino
Cerebral Arterial Diseases
Carotid and Vertebral Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time Of Flight (TOF)
The study will evaluate the efficacy and safety of Dotarem enhanced MRA in patients suffering from carotid or vertebral arterial disease.
- Trial name
- NCT01012674
- Testing
- Dotarem, TOF MRA
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Guerbet
Hydrocephalus in Infants, Hydrocephalus Acquired
CEUS Evaluation of Hydrocephalus in Neonates and Infants
Hydrocephalus affects up to 2 out of every 500 births and results in long-term disability in up to 78% of those affected. The standard treatment of hydrocephalus is cerebrospinal fluid (CSF) diversion via placement of an invasive…
- Trial name
- NCT06693752
- Testing
- Sulfur Hexafluoride Lipid Type A Microspheres 25 mg Injection Powder for Suspension [LUMASON]
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Philadelphia
Oropharyngeal Squamous Cell Carcinoma (OPSCC), HPV
Prognostic Biomarkers for Patients With Human Papillomavirus (HPV) Positive Oropharyngeal Squamous Cell Carcinoma
The purpose of this research study is to investigate the relationship between vascular habitats and treatment response AND to investigate the potential utility of dynamic contrast enhanced (DCE)-MRI derived parameters in…
- Conditions
- Oropharyngeal Squamous Cell Carcinoma (OPSCC), HPV, HPV Positive Oropharyngeal Squamous Cell Carcinoma
- Trial name
- OPSCC (NCT07797738)
- Testing
- MRI
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Contrast Induced Nephropathy
Assessment of the Effect of Atorvastatin on Prevention of CIN in Patients Undergoing Coronary Angiography
As the effect of statin use before the angiography to prevent contrast induced nephropathy (CIN) is not well-known, the aim of the current study is to assess the effect of atorvastatin on prevention of CIN in patients undergoing…
- Trial name
- CIN (NCT02113540)
- Testing
- Atorvastatin
- Where
- Iran
- Sponsor
- Isfahan University of Medical Sciences
Nephropathy
Normobaric Hyperoxygenation for Prevention of Contrast Induced Nephropathy
Acute renal failure induced by radiographic contrast agents is a known complication of coronary angiography.hypoxia plays a major role in the pathogenesis of Contrast induced nephropathy.
- Trial name
- NCT01448889
- Testing
- 100% oxigen
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Assaf-Harofeh Medical Center
Coronary Artery Disease
Acquiring Consensus for Contrast Echocardiography System Settings - ACCESS Study
This study evaluated and optimized settings for, and evaluated the performance of, AI-700-enhanced echocardiographic imaging on several ultrasound imaging platforms, as well as collected additional safety data for AI-700 in…
- Trial name
- NCT00669851
- Testing
- AI-700
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Acusphere
Coronary Disease
Lipid Rich Necrotic Core Lesion Detected by Cardiac Magnetic Resonance Imaging (CMR)
The purpose of this study is to evaluate whether some features of plaques in coronary arteries predispose the heart muscle to injuries during angioplasty in patients with a narrowing in at least one of the arteries that may need…
- Trial name
- Hawaii (NCT01284270)
- Testing
- Cardiac MRI
- Sponsor
- Piedmont Healthcare
Coronary Artery Disease
Comparison of Image Quality of Coronary Computed Tomography Angiography bEtweeN High concenTRATion and Low concEntration Contrast Agents(CONCENTRATE Trial)
According to CT technology development, cardiac CT is very useful examination as noninvasive examination and the accuracy in locating lesions has increased to 95%.
- Trial name
- NCT02549794
- Testing
- CT angiography with high concentration contrast agent, CT angiography with low concentration contrast agent (320), CT angiography with low concentration contrast agent (270)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Intracranial Pressure, Cerebral Blood Flows
Combined Flow and Pressure Study of Craniospinal Dynamic
Normal pressure hydrocephalus (NPH) can cause a type of dementia. However, this type of dementia is the only one that is reversible.
- Conditions
- Intracranial Pressure, Cerebral Blood Flows, Infusion Test, Phase Contrast MRI
- Trial name
- REVERT (NCT05068128)
- Testing
- Flow MRI, PERFUSION TEST
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Breast Cancer
Contrast-Enhanced MRI for the Characterization of Ductal Carcinoma in Situ (DCIS)
*REFERRALS TO THIS TRIAL MUST BE THROUGH BREAST CARE CLINICIANS ONLY* RATIONALE: Diagnostic procedures, such as contrast-enhanced MRI, may help find and diagnose ductal carcinoma in situ.
- Trial name
- NCT00804128
- Testing
- Magnetic Resonance Imaging (MRI), Gadavist
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of California, San Francisco