Clinical trials: Contrast-Induced Nephropathy
Cardio-Renal Syndrome
Contrast-induced Nephropathy: Incidence,Risk Factors,Effective Prevention and Management Method
This review article have included about ten thousand patients undergoing percutaneous coronary intervention (PCI), aim to identify the incidence of CIN in actual, find some new risk factors and the protecting methods for these…
- Trial name
- NCT02664246
- Testing
- percutaneous coronary intervention
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Coronary Artery Disease
IVUS Guided PCI in Patients With Chronic Kidney Disease
The incidence of contrast-induced nephropathy (CIN) is high (> 25%) in patients with severe chronic renal disease (CKD) who undergo a percutaneous coronary procedure.
- Trial name
- SPEED (NCT06813534)
- Testing
- Intravascular Ultrasound guided PCI
- Where
- 2 sites in France
- Volunteers
- 170 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aortic Valve Disease, Chronic Kidney Disease
Preventing contrAst Induced Nephropathy After TranscathEter Aortic Valve Replacement
Chronic kidney disease (CKD) and (subsequent) acute kidney injury are frequent in patients undergoing transcatheter aortic valve implantation (TAVI).
- Conditions
- Aortic Valve Disease, Chronic Kidney Disease, Contrast Induced Nephropathy, Acute Kidney Injury
- Trial name
- PANTER (NCT03121053)
- Testing
- sodium bicarbonate, hypotone saline
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- St. Antonius Hospital
Cardio-Renal Syndrome, Coronary Angiography
Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention
As a single center, retrospective observation study in Guangdong Institute of Cardiovascular Diseases, this study included the main study population of patients who underwent coronary angiography and / or coronary intervention…
- Conditions
- Cardio-Renal Syndrome, Coronary Angiography, Coronary Artery Disease, Kidney Diseases
- Trial name
- NCT04407936
- Where
- China
- Volunteers
- 88,938 people
- Sponsor
- Guangdong Provincial People's Hospital
Contract Induced Nephropathy
Study of Contrast - Induced Nephropathy After Intravenous Contrast Procedures at Sohag University Hospitals
Contrast-induced nephropathy (CIN) is a serious complication of angiographic procedures and results from administration of iodinated contrast media (CM).
- Trial name
- NCT06965764
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Kidney; Obstruction, Renal Obstruction
Contrast Enhanced Ultrasound for Renal Obstruction
This research is studying Definity ultrasound contrast agent, which is already approved by the Food and Drug Administration (FDA) for the ultrasound evaluation of the liver and heart.
- Trial name
- NCT05090800
- Testing
- Definity contrast during ultrasound
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Michigan
Contrast Induced Nephropathy
Erythropoietin in Radiocontrast Induced Nephropathy (ERIN) Trial
Full Title: A Randomized Controlled Trial of Procrit for the Prevention of Acute Renal Failure in Patients Receiving Intravenous Contrast Primary Objective: To evaluate the efficacy of a one-time dose of intravenous…
- Trial name
- ERIN (NCT00476619)
- Testing
- erythropoeitin
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Brigham and Women's Hospital
Radiographic Contrast Agent Nephropathy
Does Bicarbonate in Addition to Theophylline Reduce CIN?
Contrast-induced nephropathy (CIN) is the third most frequent cause of hospital-acquired acute renal failure. Different regimes in the prophylaxis of CIN have been investigated in the last years.
- Trial name
- NCT02643602
- Testing
- Hydration with bicarbonate in addition to theophylline, Hydration with sodium chloride in addition to theophylline
- Volunteers
- 152 people
- Sponsor
- Technical University of Munich
Acute Kidney Injury
Oral Salt and Water to Prevent Contrast Nephropathy
The purpose of this pilot trial is to determine the safety and feasibility of using oral salt and water loading compared to intravenous saline for the prevention of contrast-induced acute kidney injury in patients with chronic…
- Trial name
- NCT02084771
- Testing
- Intravenous Saline, Oral Salt and Water
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Contrast Induced Nephropathy, Acute Kidney Injury
A Maastricht Contrast-Induced Nephropathy Guidelines Study: CIN Prevention Guidelines: Appropriate & Cost-effective?
Contrast-induced nephropathy (CIN) is a side-effect of intravascular administration of iodinated contrast material. It is defined as an absolute (>44μmol/l) or relative (>25%) increase in serum creatinine from baseline values…
- Trial name
- AMACING (NCT02106234)
- Testing
- No prophylactic iv hydration
- Where
- Netherlands
- Volunteers
- 660 people
- Sponsor
- Maastricht University Medical Center
Emergent Coronary Procedure
Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate Bolus Injection
This study is to investigate the effect of Sodium Bicarbonate bolus injection in patients undergoing an emergent coronary procedure for prevention of contrast-induced nephropathy.
- Trial name
- NCT00700375
- Testing
- Sodium bicarbonate, Sodium Chloride
- Where
- Japan
- Volunteers
- 59 people
- Sponsor
- Osaka General Medical Center
Contrast-Induced Nephropathy
Theophylline, N-acetylcysteine, and Theophylline Plus N-acetylcysteine in Preventing Contrast-induced Nephropathy
The aim of this study is to determine the efficacy of Theophylline, N-Acetylcysteine and, and Theophylline plus N-acetylcysteine in the prevention of contrast-induced nephropathy.
- Trial name
- NCT02088502
- Testing
- N-acetylcysteine, Theophylline, 0.9% sodium chloride
- Where
- Iran
- Volunteers
- 96 people
- Sponsor
- Isfahan University of Medical Sciences
Acute Kidney Injury
Efficacy and Safety of Deferiprone in Patients With Chronic Kidney Disease Undergoing a Cardiac Catheterization and Receiving Contrast Agent
This trial will evaluate whether treatment with CRMD001 (unique formulations of the iron chelator, Deferiprone) will reduce morbidity and mortality in subjects with Chronic Kidney Disease (CKD) and additional risk factors.
- Trial name
- NCT01391520
- Testing
- deferiprone
- Sponsor
- CorMedix Therapeutics
Acute ST Segment Elevation Myocardial Infarction
Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention
The aim of this study is to evaluate the effects of N-acetyl cysteine on major cardiac and cerebral events in patients undergoing primary percutaneous coronary intervention who have moderate to high risk for contrast induced…
- Trial name
- EASE-PRM-PCI (NCT01878344)
- Testing
- NAC, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Suleyman Demirel University
Kidney Injury, Contrast-induced Nephropathy
Early Diagnosis as Strategy in Reducing the Incidence of Contrast-induced Nephropathy
Renal damage due to contrast media (CM) administration is one of the main complications of cardiac intervention and is called contrast-induced nephropathy (CIN).
- Trial name
- NCT04225013
- Testing
- Early kidney damage biomarkers, Predisposition to kidney injury biomarkers
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- R. Laura Vicente Vicente
Renal Insufficiency
Comparative Study of the Efficacy of Oral Versus Intravenous Hydration as a Preventive Measure of Contrast-induced Nephropathy (CIN) in Patients With Renal Insufficiency (RI) Grade III Under Study Conducting Computed Tomography (CT)
This study evaluates if oral hydratation is as effective as endovenous hydratation in the prophylaxis of contrast-induced nephropathy in patients renal insufficiency grade III under study conducting contrasted computed tomography.
- Trial name
- NICIR (NCT02872155)
- Testing
- Oral hydratation, Bicarbonate endovenous hydratation, Saline endovenous hydratation
- Where
- Spain
- Volunteers
- 264 people
- Sponsor
- David Garcia Cinca
Serum Cystatin C Before and After Coronary Angiogram, Serum Creatinine Before and After Coronary Angiogram
Limb Ischemic Preconditioning for Prevention of Contrast Media Induced Nephropathy in Diabetic Kidney Patient
Contrast media induced nephropathy (CIN) is considered to be a serious complication in patient who underwent coronary angiogram (CAG). The pathogenesis of CIN does not well understood.
- Trial name
- NCT01763034
- Testing
- limb ischemic preconditioning
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Ramathibodi Hospital
Non STEMI, Unstable Angina
Safety and Efficacy of CMX-2043 for Protection of the Heart and Kidneys in Subjects Undergoing Coronary Angiography
The objective of this study is to evaluate CMX-2043 for prevention of renal and cardiac injury associated with coronary angiography in patients with acute coronary syndrome (ACS), but excluding ST-elevation myocardial infarction…
- Trial name
- CARIN (NCT02103959)
- Testing
- CMX-2043
- Volunteers
- 361 people
- Sponsor
- Ischemix, LLC
Atherosclerosis, Contrast Induced Nephropathy
The CASABLANCA Study: Catheter Sampled Blood Archive in Cardiovascular Diseases
The purpose of this research is to determine the relationship between novel blood tests for heart function (including hormones and heart enzymes measured in the blood), and assess for kidney damage before and after angiography…
- Conditions
- Atherosclerosis, Contrast Induced Nephropathy, Renal Impairment
- Trial name
- CASABLANCA (NCT00842868)
- Where
- United States
- Volunteers
- 1,298 people
- Sponsor
- Massachusetts General Hospital
Kidney Failure, Chronic
A Safety Comparison of Iopromide and Iodixanol in Renal Impaired Patients
The investigators intend to find out which contrast agent has less kidney toxicity in renal impaired patients undergoing cardiac angiography or percutaneous coronary intervention (PCI).
- Trial name
- DIRECT (NCT00926562)
- Testing
- Iopromide (Ultravist), Iodixanol (Visipaque)
- Where
- 19 sites in China
- Volunteers
- 592 people
- Sponsor
- Chinese PLA General Hospital