Clinical trials: Contrast-Induced Nephropathy
CIN
To Compare Intravenous and Oral Hydration of the Prevention for CIN in Elderly Patients Undergoing Intravenous CECT
To Compare Intravenous and Oral Hydration of the Prevention for Contrast-induced Nephropathy in Elderly Patients Undergoing Intravenous Contrast-enhanced Computed Tomography.
- Trial name
- CINOECT (NCT03872739)
- Testing
- enhanced computed tomography
- Where
- China
- Volunteers
- 1,368 people
- Sponsor
- Yu Danqing
Contrast-induced Nephropathy, Acute Renal Failure
Prevention of Contrast-Induced Nephropathy
Patients with pre-existing kidney disease are at high risk of acute renal failure when exposed to radio-contrast dyes, for example during a cardiac angiogram.
- Conditions
- Contrast-induced Nephropathy, Acute Renal Failure, Chronic Renal Failure
- Trial name
- NCT00175227
- Testing
- intravenous saline hydration + mannitol + furosemide, intravenous saline hydration
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta
Contrast Induced Kidney Injury.
Evaluation of Sodium Bicarbonate to Reduce the Incidence of Contrast Induced Chronic Kidney Injury in Patients With Kidney Disease
Patients with Stage 3B, 4,or 5 Chronic Kidney Disease who are to undergo an angiography procedure with contrast agent will be asked if they are willing to join the trial.
- Trial name
- BOSS (NCT00930436)
- Testing
- sodium bicarbonate
- Where
- 17 sites in United States
- Volunteers
- 391 people
- Sponsor
- MD Scientific
Contrast-induced Nephropathy
Use of Urinary Cell-Cycle Arrest Biomarkers in Contrast-Associated Nephropathy After Coronary Angiography
Radiological examinations that require the administration of iodinated contrasts (IC) for diagnostic and therapeutic purposes are essential in current clinical practice, and their use in interventional procedures has been…
- Trial name
- NCT04163250
- Testing
- Urinary determination of TIMP-2/ IGFBP7
- Where
- Spain
- Volunteers
- 194 people
- Sponsor
- Eva de Miguel Balsa
Contrast Induced Nephropathy
Evaluation of RenalGuard® System to Reduce the Incidence of Contrast Induced Nephropathy in At-Risk Patients
Contrast-Induced Nephropathy (CIN) can occur when patients with pre-existing kidney problems undergo procedures that use iodinated contrast media, such as cardiac catheterizations.
- Trial name
- CIN-RG (NCT01456013)
- Testing
- RenalGuard Therapy, Standard Therapy
- Where
- 30 sites in United States
- Volunteers
- 326 people
- Sponsor
- CardioRenal Systems, Inc.
Contrast Induced Nephropathy
REduction of rIsk for Contrast Induced Nephropathy
The REduction of rIsk for Contrast-Induced Nephropathy (REICIN) study is the largest prospective multicenter data base for CIN flowing coronary angiography (CAG) or percutaneous coronary intervention (PCI).
- Trial name
- REICIN-RESCIND (NCT01402232)
- Where
- 12 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Contrast-induced Nephropathy
Ischemic Preconditioning for Prevention of Contrast Nephropathy in The Emergency Department
The purpose of this study is to demonstrate the effectiveness of ischemic preconditioning in the emergency department to prevent contrast induced nephropathy
- Trial name
- NCT03238391
- Testing
- Ischemic preconditioning
- Volunteers
- 350 people
- Sponsor
- Derince Training and Research Hospital
Stable Angina, Acute Kidney Injury
CI-AKI in Patients With Stable CAD and Comorbidities. Are we Doing Better?
Patients aged 18-89 with stable CAD and comorbidities receiving optimal medical treatment requiring PCI with iodinated contrast media.
- Conditions
- Stable Angina, Acute Kidney Injury, Contrast-induced Nephropathy
- Trial name
- NCT04014153
- Testing
- Iodinated contrast media
- Volunteers
- 1,023 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Contrast-induced Nephropathy
Coenzyme Q10 Role in Prevention of Contrast Induced Nephropathy in Acute Coronary Syndrome Patients.
In this study the investigators aim to study the effect of supplementation of CoQ10 in decreasing the incidence of contrast induced acute kidney injury in patients with acute coronary syndrome undergoing coronary angiography.
- Trial name
- NCT06429345
- Testing
- Coenzyme Q10 100 Milligrams Oral Capsule
- Where
- 2 sites in Egypt
- Volunteers
- 250 people
- Sponsor
- Ain Shams University
Contrast Induced Nephropathy
Induced Diuresis With Matched Hydration Compared to Standard Hydration for Contrast Induced Nephropathy (CIN) Prevention
This study is being proposed with the objective to assess the potential benefits of induced diuresis by furosemide with matched hydration therapy compared to standard hydration in the prevention of contrast-induced nephropathy…
- Trial name
- MYTHOS (NCT00702728)
- Testing
- Furosemide and matched saline hydration, isotonic saline solution
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Centro Cardiologico Monzino
Acute Kidney Injury, Pulmonary Embolism
Acute Kidney Injury in Patients Undergoing Contrast Exposure: VQ vs. CT
Both, CT scans and VQ scans, are used by doctors to look for pulmonary embolism. The most common reason to order a VQ scan is to avoid the IV dye.
- Conditions
- Acute Kidney Injury, Pulmonary Embolism, Contrast-induced Nephropathy
- Trial name
- VQ/CT (NCT03116139)
- Testing
- V/Q imaging, Computed tomography scan
- Where
- 5 sites in United States
- Volunteers
- 253 people
- Sponsor
- Indiana University
Nephropathy
Evaluating the Protective Effect of Pentoxifylline on Contrast Induced Nephropathy
Contrast induced nephropathy (CIN) is of great concern when using contrast media in the new era of medicine. CIN is defined as 25-50% relative increase, 0.5-1 absolute increase in serum creatinin value or 25% fall in GFR.
- Trial name
- NCT01469624
- Testing
- Pentoxifylline
- Where
- Iran
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Renal Impairment
Effects of Contrast Media on Subjects With Stable Reduced Renal Function Undergoing Contrast-Enhanced Computed Tomography
The purpose of this study is to evaluate the contrast-induced nephropathy (CIN) rate in subjects randomized to receive either Ioversol or Iodixanol for contrast-enhanced computed tomography.
- Trial name
- CINOPSIS CT (NCT00793182)
- Testing
- Ioversol 320 mgI/mL, Iodixanol 320 mgI/mL
- Where
- 13 sites in United States
- Volunteers
- 6 people
- Sponsor
- Guerbet
Contrast-induced Nephropathy
Efficacy Study of Vitamin D to Treat Contrast-induced Nephropathy
The investigators planned to research the effect of vitamin D supplementation on the incidence of contrast-induced nephropathy in patients undergoing coronary angiography.
- Trial name
- NCT02489240
- Testing
- vitamin D3 tablets
- Where
- China
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Contrast Induced Nephropathy, Metabolic Syndrome
Metabolic Syndrome and Contrast Induced Nephropathy
Prevention of contrast induced nephropathy after interventional cardiologic procedures deserves close interest because of its association with prolonged hospitalization, increased cost and increased in hospital and long term…
- Trial name
- NCT02192372
- Where
- Turkey (Türkiye)
- Volunteers
- 599 people
- Sponsor
- Ankara University
Myocardial Infarction, Death
Prognostic Impact of Organ Damage in STEMI Patients
Besides contrast-induced acute kidney injury (CI-AKI), adscititious vital organ damage such as hypoxic liver injury (HLI) may affect the survival in patients with ST-elevation myocardial infarction (STEMI).
- Conditions
- Myocardial Infarction, Death, Acute Kidney Injury, Hepatic Insufficiency
- Trial name
- NCT02800421
- Volunteers
- 668 people
- Sponsor
- Inha University Hospital
Diabetes Mellitus, Coronary Artery Disease
Metformin in Diabetic Patients Undergoing Coronary Angiography
The present study aims to evaluate the strict application of the 2018 European Society of Cardiology guidelines on myocardial revascularization, that recommends to check renal function if patients have taken metformin immediately…
- Conditions
- Diabetes Mellitus, Coronary Artery Disease, Lactic Acidosis With Diabetes Mellitus, Contrast-induced Nephropathy
- Trial name
- NO-STOP (NCT04766008)
- Testing
- Metformin
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Humanitas Hospital, Italy
Kidney Diseases, Urologic Diseases
Folic Acid for Prevention of Contrast Induced Nephropathy
The purpose of this study is to determine whether periprocedural administration of folic acid is effective in the prevention of contrast induced nephropathy in patients undergoing coronary CTA/angiography/angioplasty.
- Trial name
- FAPCIN (NCT02444013)
- Testing
- Folic acid
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Coronary Atherosclerosis, Coronary Artery Disease
Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality Imaging
In a prospective international multicenter observational study, 1080 stable chest pain patients (REALITY Advanced registry of CCTA patients) with the suspected chronic coronary syndrome will be enrolled.
- Conditions
- Coronary Atherosclerosis, Coronary Artery Disease, Contrast-induced Nephropathy, Cerebrovascular Disease
- Trial name
- REALITY (NCT02440646)
- Testing
- Coronary computed tomography angiography, Quantitative coronary angiography, intravascular imaging with percutaneous intervention
- Where
- 4 sites in Estonia, Netherlands and 1 more
- Volunteers
- 1,080 people
- Sponsor
- Central Clinical Hospital of the Russian Academy of Sciences
Coronary Artery Disease, Angina, Unstable
Contrast-associated Acute Kidney Injury in Patients With Different Types of Coronary Artery Disease
The goal of the study is to assess the prevalence of contrast-associated acute kidney injury in patients with stable coronary artery disease, ST-elevation myocardial infarction and unstable angina/NSTEMI, assess the risk factors…
- Conditions
- Coronary Artery Disease, Angina, Unstable, Angina, Stable, STEMI - ST Elevation Myocardial Infarction
- Trial name
- NCT04163484
- Testing
- Iodinated contrast
- Where
- Russia
- Volunteers
- 156 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University