Clinical trials: Contrast-Induced Nephropathy
Contrast Induced Nephropathy, Remote Ischaemic Preconditioning
Can Remote Ischaemic Preconditioning Reduce Contrast Induced Nephropathy in Patients Receiving Contrast for Computed Tomography?
Computated tomography (CT) is an invaluable medical resource for both physicians and surgeons. Contrast media are an aid to improve the diagnostic yield of CT.
- Trial name
- CT RIPC CIN (NCT01741896)
- Testing
- Remote ischaemic preconditioning
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mid Western Regional Hospital, Ireland
Contrast Induced Nephropathy
Prevention of Contrast-Induced Nephropathy in Diabetic Patients With Undergoing Coronary Angiography
The aim of this study is to determine whether sodium bicarbonate is superior to sodium chloride in preventing contrast induced nephropathy in diabetic patients undergoing coronary angiography or intervention.
- Trial name
- NCT00950079
- Testing
- Sodium bicarbonate, saline
- Where
- 9 sites in South Korea
- Volunteers
- 368 people
- Sponsor
- CardioVascular Research Foundation, Korea
Ischaemic Heart Disease, Contrast-induced Nephropathy
Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients
A large number of patients with symptomatic ischaemic heart disease undergo coronary artery bypass grafting (CABG) to alleviate their symptoms and improve prognosis.
- Trial name
- BYPASS-CTCA (NCT07022626)
- Testing
- CTCA
- Where
- 2 sites in United Kingdom
- Volunteers
- 688 people
- Sponsor
- Barts & The London NHS Trust
Contrast Induced Nephropathy
Assessment of the Effect of Atorvastatin on Prevention of CIN in Patients Undergoing Coronary Angiography
As the effect of statin use before the angiography to prevent contrast induced nephropathy (CIN) is not well-known, the aim of the current study is to assess the effect of atorvastatin on prevention of CIN in patients undergoing…
- Trial name
- CIN (NCT02113540)
- Testing
- Atorvastatin
- Where
- Iran
- Sponsor
- Isfahan University of Medical Sciences
Acute Kidney Injury, Contrast Media Toxicity
Curcuminoids and Contrast-induced Acute Kidney Injury
The objective of this study was to evaluate the role of curcuminoids in the prevention of CI-AKI in CKD patients.The result of the study was prophylactic administration with curcuminoids in addition to standard treatment reduce…
- Conditions
- Acute Kidney Injury, Contrast Media Toxicity, Curcuminoid, Chronic Kidney Diseases
- Trial name
- NCT04890704
- Testing
- Curcuminoid
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Remote Ischaemic Preconditioning, Contrast Induced Nephropathy
Use of Remote Ischaemic Preconditioning in the Prevention of Contrast Induced Nephropathy
With an increasingly ageing population the incidence of peripheral arterial disease (PAD) is rising. With approximately one quarter of all PAD patients ultimately progressing to Critical Limb Ischaemia (CLI), increased demands…
- Trial name
- NCT02516072
- Testing
- RIPC
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Changi General Hospital
Renal Failure
Sodium Bicarbonate for Prevention of Contrast-Induced Nephropathy
The purpose of this study is to determine whether hydration with sodium bicarbonate is superior to hydration with saline to prevent contrast-induced nephropathy.
- Trial name
- NCT01172353
- Testing
- sodium bicarbonate, saline
- Where
- Brazil
- Volunteers
- 301 people
- Sponsor
- Hospital Sao Lucas da PUCRS
Contrast Induced Acute Kidney Injury
The Effect of Remote Ischemic Preconditioning on Elective Percutaneous Coronary Intervention in Diabetic Nephropathy
Contrast-induced acute kidney injury (CI-AKI) is a significant iatrogenic complication of contrast media use associated with prolonged hospitalization, cardiovascular events, persistent kidney damage and increased risk of…
- Trial name
- NCT02329444
- Testing
- Remote ischemic preconditioning
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ulsan University Hospital
Atherosclerosis, Stable Angina
Remote Ischemic Preconditioning as a Method Against Subclinical Renal Injury and Contrast-induced Nephropathy
Contrast-induced nephropathy (CIN) has remained significant and severe complication of angiographic procedures despite the increasing use of preventative methods.
- Conditions
- Atherosclerosis, Stable Angina, Peripheral Artery Disease, Contrast-induced Nephropathy
- Trial name
- NCT02700958
- Testing
- Remote ischemic preconditioning
- Where
- Estonia
- Volunteers
- 160 people
- Sponsor
- Tartu University Hospital
Acute Kidney Injury
Aminophylline and Contrast Induced Nephropathy in Acute Myocardial Infarction
The purpose of this study is to determine whether additional therapy with Aminophylline to hydration with sodium bicarbonate and administration of N-acetylcysteine is more effective to prevent contrast induced acute kidney injury…
- Trial name
- NCT01594489
- Testing
- Aminophylline, Hydration plus N-acetylcisteine
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Ospedale Misericordia e Dolce
Contrast Induced Nephropathy
Contrast Medium Volume and Contrast-induced Nephropathy After Percutaneous Coronary Intervention
To investigate the predictive value of the contrast media volume to creatinine clearance (V/CrCl) ratio for the risk of contrast-induced nephropathy (CIN) (i.e., within 48-72 h) and to determine a relatively safe V/CrCl cut-off…
- Trial name
- CONVIN (NCT01399203)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Guangdong Provincial People's Hospital
ST Elevation Myocardial Infarction
Aggressive hydraTion in Patients With ST -Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention to prevenT Contrast-Induced Nephropathy
To compare the efficacy of 2 different hydration strategies, hydration according to clinical guideline and adequate hydration, on contrast-induced nephropathy in patients with STEMI undergoing primary PCI to investigate the…
- Trial name
- ATTEMPT (NCT02067195)
- Testing
- Receiving hydration with a 1 mL/kg bolus of intravenous isotonic saline (0.9% sodium chloride), 3 mL/kg.hour bolus of intravenous isotonic saline (0.9% sodium chloride)
- Where
- China
- Volunteers
- 560 people
- Sponsor
- Guangdong Provincial People's Hospital
Contrast-induced Acute Kidney Injury (CI-AKI) Following Coronary Angiogram (CI-AKI), Contrast-induced Nephropathy Following Coronary Angiogram (CIN)
Effectiveness of Remote Ischemic Preconditioning for Prevention of Contrast Induced Acute Kidney Injury in Patients Undergoing Coronary Angiograms.
The use of imaging is increasing in clinical practice, either for diagnosis or intervention. In these imaging processes, contrast medium (CM) is widely used.
- Trial name
- RIP-CI-AKI (NCT05147831)
- Testing
- Remote Ischemic Preconditioning
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Aortic Valve Stenosis, Renal Insufficiency
Remote Ischemic Preconditioning for Renal Protection in TAVI
Severe aortic stenosis remains a major cause of morbidity and mortality of the elderly affecting approximately 3% of elderly patients with an increasing number of patients undergoing transcatheter aortic valve interventions.
- Conditions
- Aortic Valve Stenosis, Renal Insufficiency, Contrast-induced Nephropathy
- Trial name
- NCT03347032
- Testing
- Remote ischemic preconditioning, Control
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Henry Ford Health System
Nephropathy
A Prospective, Randomized TrialComparing Oral N-Acetylcysteine and Intravenous Sodium Bicarbonate
The purpose of this study is to compare the efficacy of oral N-acetylcysteine and intravenous sodium bicarbonate for the prevention of Contrast-Induced Nephropathy (CIN) after cardiac catheterization.
- Trial name
- PROTECt (NCT00579995)
- Testing
- Oral N-Acetylcysteine, Sodium Bicarbonate
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Radiographic Contrast Agent Nephropathy
RenalGuard System for Prevention of Contrast Induced Nephropathy
The purpose of this study is to determine whether hydration with intravenous saline matched with urine output, using the device RenalGuard is superior to standard hydration with saline to prevent contrast-induced nephropathy.
- Trial name
- REPRECIN (NCT02029820)
- Testing
- RenalGuard
- Where
- Brazil
- Volunteers
- 210 people
- Sponsor
- Hospital Sao Lucas da PUCRS
Acute Kidney Injury, Renal Insufficiency
Preventing Contrast-induced Nephropathy: Evaluating Hydration Strategies and L-carnitine Administration
The general objective of this open, pilot study is to characterize biological parameters related to acute kidney injury among patients undergoing a programmed coronarography with injection of contrast material.
- Trial name
- CinBiCarn (NCT01786824)
- Testing
- Hydration strategy using saline, Hydration strategy using sodium bicarbonate, L-carnitine
- Where
- 5 sites in France
- Volunteers
- 9 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Contrast Induced Nephropathy
Prevention of Contrast Induced Nephropathy With Sodium Bicarbonate
This will be a randomized controlled trial closely following the original protocol in the previous study published in JAMA 2004 by Merten et al. Patients will be randomly assigned to one of two treatment groups.
- Trial name
- NCT00392405
- Testing
- 3 amps of sodium bicarbonate mixed in one liter of D5W
- Where
- United States
- Volunteers
- 656 people
- Sponsor
- Norton Community Hospital
Nephrotoxicity
Evaluation of Intravenous N-acetylcysteine to Prevent Contrast Media Induced Nephrotoxicity in an Emergency Center
The aim of the present study is to determine whether a high dose of intravenous NAC is efficient in preventing CN after emergency contrast injection in patients with renal failure.
- Trial name
- NCT01467154
- Volunteers
- 124 people
- Sponsor
- University Hospital, Geneva
Radiographic Contrast Agent Nephropathy
Renin-angiotensin-aldosterone System (RAAS) Blockade and Contrast Induced Nephropathy
The aim of the current study is to evaluate prospectively whether concomitant administration of renin-angiotensin-aldosterone system (RAAS) blockers (namely ACE-I and ARBs') influence the change in estimated glomerular filtration…
- Trial name
- NCT01525888
- Testing
- stop angiotensin converting enzyme inhibitor or angiotensin receptor blocker (ACE-I/ARB)
- Volunteers
- 100 people
- Sponsor
- Soroka University Medical Center