Clinical trials: Control
Intermittent Explosive Disorder
Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Intermittent Explosive Disorder
This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate AVP-786 for the treatment of Intermittent Explosive Disorder (IED).
- Trial name
- NCT03420222
- Testing
- AVP-786
- Where
- 9 sites in United States
- Volunteers
- 10 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Pain Control
To Evaluate the Food Effect and the Absorption Profile of Ibuprofen Controlled-Release Tablets 600 mg in Comparison to the Reference Standard Ibuprofen Tablets in Normal Healthy Volunteers
To evaluate the food effect of Ibuprofen CR Tablets 600 mg (IBUCR), and its bioavailability comparison versus 3 doses of the reference arms including Advil® Ibuprofen Tablets 200 mg (IBUAdv) and Motrin® IB Ibuprofen Tablets 200…
- Trial name
- NCT03418805
- Testing
- Advil Ibuprofen table 200 mg, Motrin IB Ibuprofen Tablets 200 mg, Ibuprofen CR Tablets 600 mg
- Where
- Taiwan
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Overseas Pharmaceuticals, Ltd.
Pain Control
Efficacy of Local Anesthetic Through Continuous Infusion
Efficacy of using continuous infusion of local anesthetic for post operative pain control following laparotomy.
- Trial name
- NCT04173312
- Testing
- Bupivacaine infusion, Saline
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Ascension Health
Improved Glycemic Control in Patients With Type 2 Diabetes
A Trial of HR17031 Injection With Hepatic Insufficiency
This study used a single-dose, open design to compare the pharmacokinetics of subjects with mild and moderate liver impairment and subjects with normal liver function.
- Trial name
- NCT05151705
- Testing
- HR17031 injection
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Control of Pregnancy, Prevention of Sexually Transmitted Infections
A Clinical Investigation to Assess the Performance of a Polyurethane Condom Versus a Latex Condom in Healthy Monogamous Couples
This investigation is designed to evaluate the performance rate of a polyurethane (PU) condom versus a standard natural rubber latex (NRL) condom.
- Trial name
- NCT04134039
- Testing
- Polyurethane (PU) condom, Natural Rubber Latex (NRL) condom
- Where
- Thailand
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Patients Needing Glucose Control
Effectiveness and Safety of the Dexcom G6 Continuous Glucose Monitoring System in Non-Critically Ill Patients in the Inpatient Setting
Effectiveness and Safety of the Dexcom G6 Continuous Glucose Monitoring System in Non-Critically Ill Patients in the Inpatient Setting
- Trial name
- NCT04879693
- Testing
- Continuous Glucose Monitoring System
- Volunteers
- 250 people
- Sponsor
- DexCom, Inc.
Impulse Control Disorder
Remission of ICD by Switching Dopamine Agonist to Levodopa/Carbidopa
The purpose of this study is to see whether the ICDs(Impulse Control Disorder) are improved and neuropsychiatric traits related to ICD are changed or not when switching dopamine agonist to levodopa/carbidopa in patients with…
- Trial name
- REIN-PD (NCT01683253)
- Testing
- Levodopa/Carbidopa(200mg/50mg), Dopaminergic Agonists
- Where
- 5 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Sandoz
Impulse Control Disorders
Restoring Cognitive Control (ReCon) in Acute Nicotine Withdrawal
The purpose of this study is to explore the safety, tolerability and activity of SXC-2023 or placebo when dosed for 5 days in adults with tobacco use disorder who voluntarily abstain from the use of cigarettes.
- Trial name
- NCT03887429
- Testing
- SXC-2023
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Promentis Pharmaceuticals, Inc.
ADHD, Controls
Validating a New Non-invasive Approach to Testing Lidocaine Effectiveness
This work will assess the reliability of a simple painless test for the effectiveness of the commonly used local anesthetic lidocaine
- Trial name
- NCT03680885
- Testing
- Lidocaine gel, Injected lidocaine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- PhenoSolve, LLC
T2DM With Inadequate Glycemic Control
CS02 vs Placebo With Metformin in Type 2 Diabetes Mellitus (T2DM)
The objective of the study is to compare the efficacy and safety of 3 doses CS02 Tablet in combination with a stable dose of metformin monotherapy against CS02 PTM (placebo) Tablet in combination with a stable dose of metformin…
- Trial name
- NCT03317028
- Where
- 13 sites in United States, Taiwan
- Volunteers
- 201 people
- Sponsor
- Center Laboratories, Inc.
Control of Pregnancy, Prevention of Sexually Transmitted Infections
A Clinical Investigation to Assess the Performance of Natural Rubber Latex Condoms in Couples
This investigation is designed to evaluate the performance rate of a new natural rubber latex (NRL) male condom.
- Trial name
- NCT03739190
- Testing
- NRL Condom
- Where
- Thailand
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Glycemic Control
Evaluation of Glucose Control in Patients With Diabetes
A randomized, multicenter, open-labeled, parallel, three group pilot study to evaluate the impact of a diabetes-specific nutritional shake on glucose control.
- Trial name
- NCT04230889
- Testing
- Usual Diet Group, Group 1 Nutritional Shake, Group 2 Nutritional Shake
- Where
- 8 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Healthy Controls
Normative Data of Brain Network Activation in Adolescents and Young Adults
Establish normative data of ElMindA's Brain Network Activation (BNA) using evoked response in two age groups: adolescents and young adults.
- Trial name
- NCT01460394
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- ElMindA Ltd
Asthma Control Level
Assessment of Asthma Control Level in Primary Care Setting in Malaysia
A prospective observational multi center study to assess the level of asthma control at Primary Care Setting; government health clinics (Klinik Kesihatan) in Malaysia.
- Trial name
- ASCOPE (NCT03804632)
- Where
- 10 sites in Malaysia
- Volunteers
- 1,011 people
- Sponsor
- AstraZeneca
Type 2 Diabetes Mellitus, Inadequate Glycaemic Control
Efficacy and Safety of Dapagliflozin and Dapagliflozin Plus Saxagliptin in Combination With Metformin in Type 2 Diabetes Patients Compared With Sulphonylurea
This study is being carried out to see if dapagliflozin and dapagliflozin plus saxagliptin as an addition to metformin is effective and safe in treating patients with type 2 diabetes when compared to glimepiride (sulphonylurea)…
- Trial name
- NCT02471404
- Testing
- Dapagliflozin, Saxagliptin, Glimepiride
- Where
- 173 sites in Czechia, Germany and 3 more
- Volunteers
- 939 people
- Sponsor
- AstraZeneca
Type 2 Diabetes Mellitus, Inadequate Glycaemic Control
A Multi-Center, Randomized, Double-Blind, Phase III Trial to Evaluate the Safety and Efficacy of Saxagliptin Co-administered With Dapagliflozin Compared to Saxagliptin or Dapagliflozin All Given as add-on Therapy to Metformin in Subject With Type 2 Diabetes
The aim of this study is to evaluate safety and efficacy of therapy with saxagliptin 5mg co-administered with dapagliflozin 5mg, compared to therapy with saxagliptin 5mg or dapagliflozin 5mg in patients who are inadequately…
- Trial name
- NCT02681094
- Testing
- Dapagliflozin, Saxagliptin
- Where
- 110 sites in United States, Canada and 4 more
- Volunteers
- 905 people
- Sponsor
- AstraZeneca
Impulse Control Disorders
Fingerprinting of Impulsivity
The study aims to examine a battery of behavioral and questionnaire measures in 4 disorders clinically associated with impulsivity and in health controls, to: 1) investigate if the different populations have a distinct behavioral…
- Trial name
- NCT02722174
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Impulse Control Disorders, Borderline Personality Disorder
fMRI in Impulsivity
This study aims to use resting-state and task based functional Magnetic Resonance Imaging (fMRI) as a tool to evaluate trait characteristics of impulsivity in subjects with borderline personality disorder.
- Trial name
- NCT02755181
- Testing
- Experimental
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Asthma Control Level
Assessment of Asthma Control Level in Malaysia
A Non-Interventional Retrospective Study To Assess The Level Of Asthma Control Among Adults at 2 Tertiary Care Centres In Malaysia; Institute Of Respiratory Medicine (IPR) And Hospital Serdang.
- Trial name
- ASCORE (NCT03295331)
- Where
- 2 sites in Malaysia
- Volunteers
- 398 people
- Sponsor
- AstraZeneca
Anti-Psychotic, Management of Manifestations of Psychotic Disorders
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
Cycle Pharmaceuticals Ltd. (Cycle) is developing an oral tablet formulation of Chlorpromazine Hydrochloride and intends to conduct bioequivalence trials to demonstrate its similarity to the RLD.
- Conditions
- Anti-Psychotic, Management of Manifestations of Psychotic Disorders, Treatment of Schizophrenia, Control Nausea and Vomiting
- Trial name
- NCT02943213
- Testing
- Chlorpromazine Hydrochloride
- Where
- South Africa
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cycle Pharmaceuticals Ltd.