Clinical trials: Control, open to volunteers
Idiopathic Fetal Growth Restriction
Fetal Growth Restriction a Case Control Study
The study aims to investigate the responsible factors that leads to idiopathic fetal growth restriction.
- Trial name
- NCT07025031
- Where
- 2 sites in Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Myasthenia Gravis, Generalized
Study of Aritinercept in Patients With Generalized Myasthenia Gravis
This clinical study will enroll patients with generalized myasthenia gravis (gMG). The goal of this clinical study is to assess the safety, tolerability, effectiveness, pharmacokinetics (how the body processes the drug) and…
- Trial name
- NCT07596901
- Testing
- Aritinercept
- Where
- 11 sites in United States
- Volunteers
- 81 people
- Sponsor
- Aurinia Pharmaceuticals Inc.
Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE)
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
The purpose of this global, multicenter, Phase 3 study is to evaluate the efficacy and safety of enpatoran over 24 weeks in participants with active cutaneous manifestations of lupus erythematosus with or without systemic…
- Trial name
- ELOWEN-1 (NCT07332481)
- Testing
- Enpatoran, Standard of care (SoC)
- Where
- 74 sites in United States, Australia and 18 more
- Volunteers
- 202 people
- Sponsor
- EMD Serono Research & Development Institute, Inc.
Breast Cancer, Colorectal Cancer
AI-Assisted Chemotherapy Side Effect Management
This two-stage adaptive randomized controlled trial evaluates the feasibility and preliminary efficacy of large language model (LLM)-assisted intervention for managing chemotherapy side effects in patients with solid tumors.
- Trial name
- ALLIANCE (NCT07198581)
- Testing
- LLM-assisted chemotherapy side effect management
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Incheon St.Mary's Hospital
Fallopian Tube Adhesion
Effect of Shockwaves on Fallopian Tubes Adhesion
The purpose of this study is to determine the effect of shock waves on fallopian tube adhesions.
- Trial name
- NCT06755528
- Testing
- Chitosan, shockwave therapy
- Volunteers
- 40 people
- Sponsor
- Cairo University
Neck Pain, Neck Pain Musculoskeletal
The Effectiveness of Dynamic Neuromuscular Stabilization (DNS) Exercises Compared to Localized Exercises and Standard Care on Pain Intensity, Neck Dysfunction, and Upper Cervical Range of Motion in Patients With Chronic Neck Pain: A Pilot Randomized Controlled Trial (RCT)
Many people experience long-lasting neck pain, which can affect daily life, work, and overall well-being. This study aims to find out which type of exercise program is most effective in reducing neck pain, improving neck…
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Chronic Neck Pain, Neck Disease
- Trial name
- DYNEX (NCT07395011)
- Testing
- Dynamic Neuromuscular Stabilization (DNS) Exercises, Local Exercises, Usual Care
- Volunteers
- 45 people
- Sponsor
- Hochschule Osnabruck
Metastatic Bone Disease
Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial
The goal of this clinical trial is to find out if removing and replacing part of the hip bone works better than using metal hardware to stabilize the bone in patients whose cancer has spread to the hip. The main questions are: 1.
- Trial name
- PERFORM (NCT06863129)
- Testing
- Internal Fixation, Resection and reconstruction
- Where
- 13 sites in United States, Austria and 2 more
- Volunteers
- 334 people
- Sponsor
- Michelle Ghert, MD
Healthy Adult Participants
Safety, Tolerability, and Pharmacokinetic Evaluation of ADB116 for Injection
A Phase I Study of ADB116 for Injection in Healthy Chinese Adults. This study aims as follows: Primary Objective: To evaluate the safety and tolerability of a single intravenous bolus dose of ADB116 for injection in healthy…
- Trial name
- NCT07729839
- Testing
- ADB116 for Injection
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Jiangsu Aidea Pharmaceutical Group Co., Ltd.
Painful Diabetic Neuropathy
Low-Dose Naltrexone for the Treatment of Painful Diabetic Neuropathy
Diabetes affects more than 30 million people in the United States and is a leading cause of morbidity. Over 25% diabetics also suffer from debilitating painful diabetic neuropathy in the lower legs and feet.
- Trial name
- NCT04678895
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Nicotine Dependence, Nicotine Withdrawal
Auricular Stimulation for Nicotine Withdrawal in Psychiatric Inpatients
The goal of this clinical trial is to evaluate the feasibility and preliminary effectiveness of auricular acupressure (ear seeds) combined with nicotine replacement therapy (NRT) in psychiatric inpatients (both male and female…
- Conditions
- Nicotine Dependence, Nicotine Withdrawal, Tobacco Use Disorder, Anxiety
- Trial name
- NCT07466875
- Testing
- Auricular acupressure, Nicotine Replacement Therapy (Nicotine patch plus NRT gum or lozenge)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chiao-Chiao Liao
Adaptive Support Condition, Standard Training Condition
EDA-Based Adaptive Support in VR ALS Training
This randomized controlled study aims to investigate the effects of an electrodermal activity (EDA)-based adaptive support system on performance during virtual reality (VR)-based advanced life support (ALS) training.
- Trial name
- NCT07650019
- Testing
- EDA-Based Adaptive Support System, Standard VR-Based Training
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Stroke
Implementation of a HABIT-ILE Intervention at Home for Chronic Stroke
This study will use a randomized controlled trial design to assess the possible difference between two intensive treatment programs: a classic "Hand and Arm Bimanual Intensive Therapy Including Lower Extremities" (HABIT-ILE)…
- Trial name
- HABITILEhome (NCT05727111)
- Testing
- Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) implemented at the patient home, Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE), Follow-up Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) at the patient's home
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Université Catholique de Louvain
Postoperative Pain, Postoperative Nausea and Vomiting (PONV)
Transauricular Vagus Nerve Stimulation Frequencies for Postoperative Pain
The goal of this clinical trial is to learn whether different frequencies of transauricular vagus nerve stimulation (tVNS) can reduce postoperative pain and opioid consumption in adults undergoing abdominal or urologic surgery.
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting (PONV), Opioid Consumption, Postoperative
- Trial name
- TVNS-PAIN (NCT07633444)
- Testing
- Transauricular Vagus Nerve Stimulation (tVNS)
- Where
- Brazil
- Volunteers
- 174 people
- Sponsor
- Federal University of Bahia
Patients With Cardiovascular Disease, Healthy Participants
OCTA in Cardiovascular Disease and Healthy Controls
This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy…
- Trial name
- NCT07359664
- Testing
- Retinal vascular assessment using OCTA and SLDF
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Chronic Kidney Disease Stage 3, Chronic Kidney Disease
Clinical Effectiveness of MyNutriKidney®
This study is a 6-month, pragmatic, multi-center, sequentially recruited, stratified, open-label randomized controlled trial (RCT) conducted in Malaysia.
- Conditions
- Chronic Kidney Disease Stage 3, Chronic Kidney Disease, Chronic Kidney Disease Stage 5, Chronic Kidney Disease Stage 4
- Trial name
- NCT06956872
- Testing
- Counseling, Renal Diet App, Printed Nutrition Pamphlet
- Where
- Malaysia
- Volunteers
- 200 people
- Sponsor
- Universiti Putra Malaysia
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Renal Stones
Efficacy and Safety of Flexible Ureteroscopy Versus Percutaneous Nephrolithotomy in Management of Staghorn Stones
Percutaneous nephrolithotomy (PCNL) is considered the treatment of choice for management of large renal calculi larger than 2 cm based on the yearly updated European Association of Urology (EAU) guidelines.
- Trial name
- NCT07322471
- Testing
- Percutaneous nephrolithotomy, Flexible ureteroscopy
- Where
- Egypt
- Volunteers
- 138 people
- Sponsor
- Menoufia University
Intrauterine Adhesions
Clinical Study of i-PRF Intrauterine Perfusion for Endometrial Regeneration and Repair in Moderate to Severe Intrauterine Adhesions
Intrauterine adhesions (IUA) caused by endometrial basal layer injury can lead to reduced menstrual flow, infertility, recurrent pregnancy loss, and poor reproductive outcomes.
- Trial name
- IPRF-IUA (NCT07536971)
- Testing
- Injectable Platelet-Rich Fibrin, Sodium Hyaluronate
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Obstetrics and Gynecology Hospital
Skin Wound
To Evaluate The Skin Closure Time, Parents' Satisfaction, Post Operative Mental Health, Wound Cosmesis and Wound Complication Of Skin Closure Using Adhesive Glue, Adhesive Tape And Suture In Paediatric Surgery Patients
This study is a randomised controlled trial to evaluate the skin closure time, parents' satisfaction, post operative mental health, wound cosmesis and wound complication of skin closure using adhesive glue, adhesive tape and…
- Trial name
- NCT06713772
- Testing
- Dermabond Mini, 0.36ml, Ethicon Johnson and Johnson, Somerville, New Jersey, USA, Steri-StripsTM (3M, St. Paul, Minnesota, USA, Monosyn, B.Braun, 118 Pfieffewiesen, Melsungen, Germany
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- National University of Malaysia
Lipedema
Mind-Body Chair Yoga for Functional Mobility in Individuals With Lipedema
Lipedema is a chronic condition characterized by abnormal accumulation and distribution of adipose tissue, most commonly affecting the lower extremities, and may be associated with swelling, discomfort, reduced mobility, and…
- Trial name
- LIP-MOVE (NCT07917195)
- Testing
- Mind-Body Chair Yoga + Support Group, Support Group
- Volunteers
- 73 people
- Sponsor
- Cynthia Beers
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