Clinical trials: Control, open to volunteers
Anaemia
Tranexamic Acid for Anaemia Trial
Anaemia is when the body does not have enough healthy red blood cells to carry oxygen. It is common in women because they lose blood every month during their periods.
- Trial name
- WOMAN-3 (NCT06519422)
- Testing
- Tranexamic Acid 500 MG
- Where
- 3 sites in Nigeria, Pakistan and 1 more
- Volunteers
- 4,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Pregnancy Related, Anemia, Iron Deficiency
Early Antenatal Support for Iron Deficiency Anemia
This is a randomized, controlled multi-site trial of iron therapy in pregnancy. The purpose of this research is to see if second trimester initiation of intravenous (IV) iron therapy is better than oral iron therapy for treatment…
- Conditions
- Pregnancy Related, Anemia, Iron Deficiency, Anemia of Pregnancy
- Trial name
- EASI-A (NCT04278651)
- Testing
- Ferumoxytol, Ferrous Sulfate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Thomas Jefferson University
Cystic Fibrosis
Impact of a Coordinated Dietetic-adapted Physical Activity Program on the Percentage of Lean Body Mass in Adults With Cystic Fibrosis Treated With Elexacaftor-Tezacaftor-Ivacaftor: Multicentre Randomised Controlled Trial
Cystic fibrosis is an autosomal recessive inherited disease linked to various mutations in the gene coding for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, with respiratory and digestive disorders…
- Trial name
- DIAPASOM (NCT06457451)
- Testing
- DIAPASOM program
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Testicular Abnominalies
Study to Evaluate the Effect of Zoliflodacin on Testicular Function in Healthy Adult Men
This study is a randomized, double-blind, placebo-controlled clinical trial to evaluate the effect of zoliflodacin on testicular function in healthy adult men.
- Trial name
- NCT07640477
- Testing
- Zoliflodacin
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Global Antibiotics Research and Development Partnership
Gastric Cancer (GC), Stomach Neoplasms
TEAS Timing for Gastrectomy Recovery (TEAS-TIME Trial)
The goal of this clinical trial is to learn if transcutaneous electrical acupoint stimulation (TEAS) works to help people recover faster after laparoscopic surgery for stomach cancer.
- Trial name
- NCT07714980
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- 13 sites in China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Major Depressive Disorder
Magnesium Bisglycinate in Major Depressive Disorder
Depression is a common illness that can affect a person's mood, sleep, energy, ability to work, and overall quality of life. While medicines are available to treat depression, many people do not get complete relief from their…
- Trial name
- DReAM-BiG (NCT07633080)
- Testing
- Magnesium Bisglycinate, Microcrystalline cellulose
- Where
- India
- Volunteers
- 84 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Stroke, Sabacute Stroke
Bilateral Robot-assisted Upper Extremity Rehabilitation on Motor Recovery in People With Subacute Stroke
The goal of this clinical trial is to study the clinical effects of a robotic rehabilitation treatment through a bilateral exoskeleton (Bilateral Robot-Assisted Therapy-BRAT) during standard rehabilitation, on motor recovery…
- Trial name
- BILAX (NCT06906588)
- Testing
- Experimental, Control
- Where
- 3 sites in Italy
- Volunteers
- 70 people
- Sponsor
- IRCCS San Raffaele Roma
Moderate Depression, Severe Depressive Episode Without Psychotic Symptoms
A Randomized Clinical Trial Comparing Active Versus Sham T-PEMF Headband Treatment for Depression
An 8-week, two-armed, randomized-controlled trial that examines the antidepressant effect of treatment with transcranial pulsed electromagnetic fields (T-PEMF) in patients diagnosed with moderate to severe depression using using…
- Conditions
- Moderate Depression, Severe Depressive Episode Without Psychotic Symptoms, Recurrent Depressive Disorder, Current Episode Moderate, Recurrent Depressive Disorder, Current Episode Severe Without Psychotic Symptoms
- Trial name
- NCT06005103
- Testing
- Treatment with MoodHeadBand (T-PEMF treatment)
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Advanced Non-Small Cell Lung Cancer (NSCLC)
Immunodynamics-Guided Optimization of Individualized Immunochemotherapy in Advanced Driver-Negative NSCLC: A Randomized Trial
The goal of this clinical trial is to evaluate whether individualized sequencing of immunotherapy and chemotherapy based on immune dynamics can improve treatment outcomes in adults with advanced non-small cell lung cancer (NSCLC)…
- Trial name
- NCT07190027
- Testing
- Arm 1: Standard Synchronous Group, Arm 2:Fixed Delay Group, Arm 3: Individualized Delay Group
- Volunteers
- 246 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Anxiety Disorders
The Efficacy of an AI-Based Rehabilitation Treatment in Patients With Anxiety Disorders
The trail aimed to test the efficacy of AI-based rehabilitation treatment in patients with anxiety disorders. Specifically, the objective of this trial is to determine whether the AI-based rehabilitation combined with treatment…
- Trial name
- NCT07545070
- Testing
- AI-based rehabilitation treatment combined with standard treatment, Treatment as Usual (TAU)
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Shanghai Mental Health Center
Vitiligo
A Proof of Concept, Phase 1 Study of CGB-600 for the Topical Treatment of Non-Segmented Facial Vitiligo
The goal of this clinical trial is to learn if drug CGB-600 works to treat vitiligo on the face and neck in participants between 18-60 years of age. It will also learn about the safety of CGB-600.
- Trial name
- NCT07357870
- Testing
- Drug: CGB-600 gel, experimental drug
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- CAGE Bio Inc.
Laparoscopic Surgical Procedures, Airway Control
Evaluation of SaCo VLMA for General Anesthesia for Laparoscopic Procedures
Evaluation of new supraglottic device SaCo VLMA for laparoscopic procedures under general anesthesia in comparison with other airway management methods including other supraglottic devices.
- Conditions
- Laparoscopic Surgical Procedures, Airway Control, Anesthesia
- Trial name
- NCT07391969
- Testing
- SaCo VLM or SAD or ET for airway control for laparoscopy
- Volunteers
- 20 people
- Sponsor
- Medical University of Lodz
Brain Insulin Sensitivity, Healthy Controls
Do Antipsychotics Block Insulin Action in the Brain: is it a Class Effect?
This study aimed at helping researchers understand how a medication called haloperidol can affect insulin action in the brain. Insulin is a hormone in the body that controls sugar levels in part by lowering the amount of glucose…
- Conditions
- Brain Insulin Sensitivity, Healthy Controls, Cognition
- Trial name
- NCT07109245
- Testing
- Haloperidol, Insulin Lispro, Saline
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Aerobic Physical Exercise, Traditional Strength Exercise
Acute Effects of Exercise in Peripheral Arterial Disease Patients
Peripheral arterial disease (PAD) affects over 200 million people worldwide and is caused by narrowing of the arteries. Intermittent claudication, characterized by pain when walking, is its main symptom.
- Conditions
- Aerobic Physical Exercise, Traditional Strength Exercise, Circuit Strength Exercise, Control
- Trial name
- VESSEL-FIT (NCT07248137)
- Testing
- Aerobic exercise, Traditional strength exercise, Circuit strength exercise
- Volunteers
- 16 people
- Sponsor
- European University Miguel de Cervantes
Minor, Scoliosis; Juvenile
Evaluation of a Prehabilitation Program in Patients Requiring Scoliosis Surgery.
Scoliosis is a curvature of the spine that, in the most severe cases, may require surgical treatment. This surgery is invasive and complex, causing anxiety for children, adolescents, and their parents.
- Conditions
- Minor, Scoliosis; Juvenile, Scoliosis; Adolescence, Surgery
- Trial name
- PHYPSYSCOL (NCT07852286)
- Testing
- Pre-habilitation program
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Electromagnetic Radiation (5GFR2)
The Effects of 5G Radiation on Skin
The current 5G waves used on the daily life are ranging from 410 MHz to 7125 MHz and are called FR1. The next deployed 5G waves will be FR2, from 24.45 GHz to 52.6 GHz.
- Trial name
- SEAwave (NCT05933954)
- Testing
- 5GFR2 non ionizing EMW exposure
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Prof. Olivier Gaide, MD-PhD
Diaphragm Thickness, Dyspnoea
Abdominal Air-Pressure Resistance Versus Abdominal Weight Training for Improving Diaphragm Function in Healthy Young Adults
This study aims to compare the effects of abdominal air pressure resistance training, abdominal weight training, and breathing exercises on diaphragmatic strength, endurance, and physiological responses in young healthy adults.
- Trial name
- NCT07795905
- Testing
- Abdominal Air Pressure Resistance Training, Abdominal Weight Training (AWT), Breathing Exercise Control (BE)
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Influenza, COVID-19
Routine Application of Point-of-care PCR Test to Identify and Direct Therapy for Acute Respiratory Infection in the Emergency Department Trial
The RAPID-ARIED Trial is a pragmatic, single-centre, parallel group, open-label, randomised controlled trial to be conducted in the Accident and Emergency Department of Queen Mary Hospital in Hong Kong.
- Conditions
- Influenza, COVID-19, Acute Respiratory Infections (ARIs)
- Trial name
- RAPID-ARIED (NCT06780566)
- Testing
- Point-of-care PCR testing for respiratory viruses, Laboratory PCR testing for respiratory viruses
- Where
- Hong Kong
- Volunteers
- 1,050 people
- Sponsor
- The University of Hong Kong
STEMI - ST Elevation Myocardial Infarction
Reperfusion Approach in Predicted In-hospital Delay for Primary PCI in STEMI
This study aims at evaluating of the effectiveness of in-hospital thrombolysis for ST-segment elevation myocardial infarction in PCI centers under conditions of predicted in-hospital delay (>60 min after admission in PCI-center)…
- Trial name
- RAPID-STEMI (NCT07641231)
- Testing
- Single, weight-adjusted i.v. bolus of tenecteplase, catheterisation
- Where
- Russia
- Volunteers
- 240 people
- Sponsor
- National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus
Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery
Study Objectives This study aims to investigate the effects of preoperative stellate ganglion block and intraoperative intravenous dexmedetomidine on postoperative sleep disturbance in patients undergoing laparoscopic gynecologic…
- Conditions
- Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus, Endometriosis, Endometrial Cancer
- Trial name
- NCT07860203
- Testing
- DEX 0.2 μg/kg/h., SGB
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Catherin Zhang
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