Clinical trials: Control Group, active
Impaired Fasting Glucose (IFG), Impaired Glucose Tolerance (Prediabetes)
Effect of a Food Supplement on Glycemic Parameters in Patients With Impaired Glucose Metabolism
The primary objective will be to evaluate the efficacy of GlycoDual in reducing fasting plasma glucose (FPG) and post-prandial plasma glucose (PPG) levels compared to placebo after 90 days of treatment.
- Trial name
- NCT07263802
- Testing
- GlycoDual
- Volunteers
- 90 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Mental Disorders, Substance Use Disorders
Promoting Recovery by Overcoming Self-stigma in Mental Health Disorders With a Narrative Enhancement and Cognitive Therapy (NECT) Group Intervention
This study will evaluate whether Narrative Enhancement and Cognitive Therapy (NECT) can promote recovery among adults living with severe mental health disorders, including substance use disorders.
- Trial name
- NCT07735481
- Testing
- Narrative Enhancement Cognitive Therapy, Control Group Sessions
- Where
- Switzerland
- Volunteers
- 106 people
- Sponsor
- Louise Penzenstadler
Parkinson's Disease, Progressive Supranuclear Palsy(PSP)
Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers
This research employs AI to analyze facial expressions and speech patterns, aiming to develop new digital tools for diagnosing and differentiating Parkinson's disease and similar disorders.
- Conditions
- Parkinson's Disease, Progressive Supranuclear Palsy(PSP), Multiple System Atrophy, Healthy Control
- Trial name
- NCT07392411
- Testing
- video recording
- Where
- China
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Severe Asthma
Tezepelumab in the Treatment of Emergency Room Asthma in Adults (TERAA)
Adults with severe asthma may have sudden worsening shortness of breath that results in their going to Emergency Department for urgent care.
- Trial name
- TERAA (NCT06705764)
- Testing
- Tezepelumab
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Left Ventricular Thrombus, Myocardial Infarction
Anticoagulation in Post MI LV Thrombus Trial in Nepal
Introduction: The prevalence of left ventricular(LV) thrombus after acute myocardial infarction has decreased with thrombolysis and primary angioplasty intervention worldwide.
- Trial name
- WaRMIN (NCT05794399)
- Testing
- Rivaroxaban, Warfarin
- Where
- Nepal
- Volunteers
- 196 people
- Sponsor
- Shahid Gangalal National Heart Centre
Hysterosalpingography-Related Pain
Pain Control During Hysterosalpingography: A Three-Arm Randomized Trial
Hysterosalpingography (HSG) is commonly performed during infertility evaluation and may cause pain during cervical manipulation, uterine distension, and contrast-medium injection.
- Trial name
- HSG-PAIN (NCT07792668)
- Testing
- Indomethacin 100Mg Suppository, Lidocaine %2 ampoule
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Diabetes Mellitus, Acupressure
Effect of Acupressure on Blood Glucose And Anxiety in Elderly With Diabetes
This study aims to evaluate the effects of acupressure on blood glucose levels and anxiety in older adults with diabetes. A three-arm randomized controlled trial will be conducted, comparing acupressure, sham acupressure, and…
- Trial name
- NCT07356024
- Testing
- Acupressure, Routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Type 1 Diabetes
Evaluating the InPen in Pediatric Type 1 Diabetes
Type 1 Diabetes (T1D) is the most common form of diabetes affecting children, requiring lifelong administration of insulin to prevent complications.
- Trial name
- EMPoWER (NCT05515939)
- Testing
- InPen Insulin Pen
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Wayne State University
Type 2 Diabetes, Appetite Regulation
GLycaemic Outcomes With Whey Protein in ageING
The goal of this placebo-controlled, partial crossover design study is to identify the impact of consuming whey protein before meals on free-living glucose control in older adults living with type 2 diabetes.
- Conditions
- Type 2 Diabetes, Appetite Regulation, Whey Protein, Ageing and Geriatric Health
- Trial name
- GLOWING (NCT07285811)
- Testing
- Glycaemic control with whey protein, Glycaemic control with different doses of whey protein
- Where
- 2 sites in United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Bilateral Breast Carcinoma, Breast Inflammatory Carcinoma
Multi-epitope Folate Receptor Alpha Peptide Vaccine, GM-CSF, and Cyclophosphamide in Treating Patients With Triple Negative Breast Cancer
This randomized phase II trial studies how well multi-epitope folate receptor alpha peptide vaccine, sargramostim (GM-CSF), and cyclophosphamide work to prevent the recurrence of stage 1-3 triple negative breast cancer.
- Conditions
- Bilateral Breast Carcinoma, Breast Inflammatory Carcinoma, Stage IB Breast Cancer AJCC v7, Stage II Breast Cancer AJCC v6 and v7
- Trial name
- NCT03012100
- Testing
- Cyclophosphamide, Laboratory Biomarker Analysis, Multi-epitope Folate Receptor Alpha Peptide Vaccine
- Where
- 12 sites in United States
- Volunteers
- 280 people
- Sponsor
- Academic and Community Cancer Research United
HİP FRACTURE, Hip Surgery (Lateral Incision)
Perioperative Analgesic Effects of PENG Versus PENG Plus LFCN Block in Hip Surgeries
This study is designed to find the best way to control pain after hip surgery performed through a side (lateral) incision. Two different types of nerve blocks used before the operation will be compared.
- Conditions
- HİP FRACTURE, Hip Surgery (Lateral Incision), Postoperative Pain Management, Analgesia, Postoperative
- Trial name
- NCT07329829
- Testing
- Pericapsular nerve group (PENG) block, Lateral Femoral Cutaneous Nerve (LFCN) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Coeliac Disease, Celiac Disease
A Phase 2a/b Study of the Efficacy and Safety of Subcutaneous Amlitelimab in Adults With Nonresponsive Celiac Disease
This is a Phase 2a/b, randomized, double-blind, placebo-controlled, parallel-group, 6-arm study to evaluate the efficacy and safety of amlitelimab in adult participants with non-responsive celiac disease (NRCD) who are on a…
- Trial name
- NCT06557772
- Testing
- Amlitelimab, SIGE, Gluten-free product (GFP)
- Where
- 118 sites in United States, Argentina and 19 more
- Volunteers
- 229 people
- Sponsor
- Sanofi
Schizophrenia and Schizoaffective Disorder
A Trial of Group Cognitive Behavioral Therapy for Psychosis (the Feeling Safe Programme)
Schizophrenia is a serious psychiatric disorder characterized by delusions, hallucinations, negative symptoms and disorganized behaviour.
- Trial name
- NCT07408934
- Testing
- Cognitive Behavioral Therapy for Psychosis
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
PARKINSON DISEASE (Disorder), Parkinsonism or Parkinson's Disease Nos
Strength and Dual-Task on Sarcopenia in People With Parkinson's Disease
Parkinson´s disease and parkinsonian syndromes are associated with progressive motor and non-motor impairments that may compromise functional independence and quality of life.
- Trial name
- SARCOPARKINSON (NCT07907302)
- Testing
- Nutricional Education and General Exercise Guidelines, Progressive Resistance Training With Cognitive Dual-Task Training, Progressive Resistance Training With Cognitive Dual-Task and Inestability Training
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Valencia
Treatment-resistant Schizophrenia
Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant Schizophrenia
This is a prospective, 12-week, randomized, double-blind, placebo-controlled study, designed to evaluate the efficacy, safety, and tolerability of a dose of evenamide of 15 mg bid, compared to placebo, as add-on treatment in…
- Trial name
- ENIGMA-TRS 2 (NCT07184619)
- Testing
- Evenamide 15 mg bid
- Where
- 19 sites in United States, Argentina and 2 more
- Volunteers
- 400 people
- Sponsor
- Newron Pharmaceuticals SPA
Chronic Spinal Pain
Protocol for a Randomized Controlled Trial Comparing the Effectiveness of Mechanical Diagnosis and Therapy Versus Generalized Exercise for Reducing Pain in Surgeons With Chronic Spinal Pain
Surgeons frequently experience chronic spinal pain due to prolonged static postures and repetitive movements during surgical procedures.
- Trial name
- NCT07293130
- Testing
- Mechanical Diagnosis and Therapy (MDT), Generalized Exercise
- Where
- Denmark
- Volunteers
- 62 people
- Sponsor
- Claus Kjærgaard
Respiratory Synctial Virus Infections
Evaluation of the Effect of Nirsevimab on Hospitalizations Due to RSV Infection in Infants Under One Year of Age.
This study aims to evaluate the impact of Nirsevimab, a monoclonal antibody used for RSV prophylaxis, on reducing RSV- related hospitalizations. It will be conducted at 8 pediatric departments in Tuscany, Italy.
- Trial name
- NCT06856967
- Testing
- Nirsevimab
- Where
- 8 sites in Italy
- Volunteers
- 138 people
- Sponsor
- Meyer Children's Hospital IRCCS
Cognitive Decline, Mild, Alzheimer Disease
Fasudil Trial for Treatment of Early Alzheimer's Disease (FEAD)
The goal of this placebo-controlled double-blind Phase 2 clinical trial is to test in people with early Alzheimer's Disease. The main questions it aims to answer are: Does treatment with fasudil, a ROCK-inhibitor, lead to…
- Trial name
- FEAD (NCT06362707)
- Testing
- Fasudil
- Where
- 6 sites in Norway
- Volunteers
- 200 people
- Sponsor
- Helse Stavanger HF
Bipolar Disorder
Metacognitive Training With Bipolar Disorder Patients.
The guiding question of this project is to evaluate the effectiveness of MCT as a form of ToM rehabilitation in patients diagnosed with BD who have deficits in this domain of social cognition.
- Trial name
- NCT04447807
- Testing
- Metacognitive Training, Treatment as Usual
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- University of Sao Paulo
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