Clinical trials: Controlled Diabetes
Gastroparesis, Diabetes Mellitus
A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis Study 03
A 46-week study to compare the efficacy of relamorelin with that of placebo in participants with diabetic gastroparesis (DG). At the end of the 40-week Treatment Period, participants will either continue on relamorelin or placebo…
- Trial name
- NCT03420781
- Testing
- Relamorelin
- Where
- 337 sites in United States, Argentina and 24 more
- Volunteers
- 467 people
- Sponsor
- Allergan
Type2 Diabetes
The Blood Glucose Control in Patients With Type 2 Diabetes Treated With Glargine
Glargine is commonly used in insulin supplemental therapy in patients with type 2 diabetes(T2D) at present. This study aims to investigate the current status of blood glucose control in patients with T2D treated with glargine.
- Trial name
- NCT03566472
- Testing
- Continuous Glucose Monitoring System
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Diabete Mellitus
Clinical Trial to Evaluate the Efficacy and Safety of DA-5218 in Patients With Type 2 Diabetes
This study is a multicenter, double-blind, active-controlled, randomized, parallel, phase IV clinical trial to evaluate the efficacy and safety of DA-5218 in patients with type 2 diabetes who have inadequate glycemic control with…
- Trial name
- NCT07229534
- Testing
- DA-5218, DA-5218-C
- Volunteers
- 238 people
- Sponsor
- Dong-A ST Co., Ltd.
Diabetic Retinopathy
Assessment of Retinal Microvascular Changes by OCT Angiography in Diabetic Retinopathy
This observational cross-sectional study aims to assess retinal microvascular changes using optical coherence tomography angiography (OCTA) in patients with diabetic retinopathy.
- Trial name
- NCT07747428
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Type 1 Diabetes
Physical Activity and Glycemic Control in Adolescents
The purpose of this pilot study is to evaluate the initial efficacy of a reinforcement intervention to enhance physical activity levels in sedentary adolescents and young adults with type 1 diabetes (T1D).
- Trial name
- NCT02674828
- Testing
- Reinforcement for meeting targeted physical activity goals, Standard of Care
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Yale University
End Stage Kidney Disease (ESKD)
A Phase 1b Study to Evaluate the PK of CSL300 (Clazakizumab) in Chinese Subjects With End Stage Kidney Disease (ESKD)
This is a phase 1b, partial-blind (Sponsor unblinded), randomized, multicenter, placebo-controlled study. The primary objective of this study is to evaluate the pharmacokinetics (PK) of CSL300 after single and multiple doses in…
- Trial name
- NCT07619820
- Testing
- CSL300
- Where
- China
- Volunteers
- 24 people
- Sponsor
- CSL Behring
Type 1 Diabetes Mellitus With Hypoglycemia
A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes
The goal of this clinical trial is to learn about the effect of the study drug (ZT-01) on low blood sugar (hypoglycemia) in adults with type 1 diabetes (T1D) who have been having low blood sugars ("hypos") at night.
- Trial name
- ZONE (NCT05762107)
- Testing
- ZT-01, 7 mg, ZT-01, 15 mg, ZT-01, 22 mg
- Where
- 46 sites in United States, Canada
- Volunteers
- 186 people
- Sponsor
- Zucara Therapeutics Inc.
Obesity, Diabetes
Effect of Pomegranate Extract Intake on Body Composition and Blood Pressure.
Pomegranate has gained widespread popularity since the health effects of the whole fruit, as well as its juices and extracts, have been studied in relation to a variety of chronic conditions such as hypertension, diabetes…
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- NCT02017132
- Testing
- Pomegranate extract
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Cystic Fibrosis, Pancreatic Insufficiency
Effect of Chronic Incretin-based Therapy in Cystic Fibrosis
In recent years, diabetes has emerged as one of the most significant co-diseases that many Cystic Fibrosis (CF) patients develop.
- Trial name
- NCT01879228
- Testing
- Sitagliptin
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Pennsylvania
Diabetes
Improved Glycemic Control in Adult Subjects With Type 1 Diabetes on MDI Using Insulin Guidance Software
140 subjects will be enrolled into the clinical study and randomized into the Control Group or the Experimental Group by block randomization. The subjects must meet all inclusion and none of the exclusion criteria.
- Trial name
- NCT00552734
- Testing
- Insulin Guidance Software
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes
The Effectiveness of Resistance Exercise for Glycemic Control in Type 2 Diabetes Mellitus Patients
Resistance exercise is effective in improving glycemic control in diabetes patients. The effectiveness of a home-based resistance exercise program has not been establish.
- Trial name
- RE (NCT01387334)
- Testing
- Resistance Exercise Training Program With Rubber Bands
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Diabetes Mellitus, Type 2
A Study to Evaluate the Efficacy and Safety of the Addition of Canagliflozin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin and Sitagliptin
The purpose of this study is to assess the effect of canagliflozin (JNJ-28431754) compared to placebo in the treatment of participants with Type 2 Diabetes Mellitus (T2DM), who have inadequate glycemic control on maximally or…
- Trial name
- NCT02025907
- Testing
- Canagliflozin, 100 mg, Canagliflozin, 300 mg
- Where
- 57 sites in United States, Australia and 3 more
- Volunteers
- 218 people
- Sponsor
- Janssen Research & Development, LLC
Type 1 Diabetes (T1D), Nutrition Therapy
Meal Frequency and Glycemic Control in Individuals With Type 1 Diabetes
The goal of this clinical trial is to examine the effect of 3 versus 6 daily meals of isocaloric diets on glycemic control and variability in individuals with type 1 diabetes.
- Conditions
- Type 1 Diabetes (T1D), Nutrition Therapy, Glycemic Control for Diabetes Mellitus
- Trial name
- NCT06934707
- Testing
- Three meals a day, Six meals a day
- Where
- Brazil
- Volunteers
- 27 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Type 2 Diabetes
A Clinical Study of Insulin Degludec Injection in Subjects With Type 2 Diabetes
This study is a multi-center, randomized, open-label, parallel, positive-controlled registered clinical study,to evaluate the efficacy and safety of insulin degludec injection developed by Chia Tai Tianqing Pharmaceutical Group…
- Trial name
- NCT04955834
- Testing
- Insulin degludec injection, Tresiba®
- Where
- 2 sites in China
- Volunteers
- 344 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Diabetes Mellitus, Type 2
Determining the Effect on Patients of Internet-Based Diabetes Disease Management
This grant supports a 12-month randomized controlled trial comparing usual care versus collaborative disease management over the Internet among disadvantaged African-Americans with Type 2 diabetes.
- Trial name
- NCT00220207
- Testing
- Internet co-management module
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Robert Wood Johnson Foundation
Type 2 Diabetes Mellitus (T2DM)
Spiritual Care for Psychological and Glycemic Outcomes in Type 2 Diabetes
This study aims to evaluate the effects of integrating spiritual care into the management of patients with type 2 diabetes mellitus.
- Trial name
- SC-DMT2 (NCT07333625)
- Testing
- Spiritual Care Program, Standard Diabetes Care
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Noor Huda Mustofa
Type 2 Diabetes Mellitus
Study of Multiple Oral Doses of PF-07081532 in Adult Participants With Type 2 Diabetes Mellitus
This is a Phase 1, randomized, placebo-controlled, double-blind (investigator- and participant-blinded), sponsor-open study of PF-07081532.
- Trial name
- NCT05158244
- Testing
- PF-07081532
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Pfizer
Diabetes Mellitus 2 Type
Comparison of Two Insulin Regimens in Optimally-controlled Patients With DM2.
Intensive Insulin Therapy (IIT) may be given in Type 2 Diabetes (T2DM) in two different ways : as Basal/bolus therapy (B/B) in four-five injections per day . as Modern Premixed Insulins( MPI's) three times per day .
- Trial name
- NCT01627509
- Where
- 2 sites in Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Type 1 Diabetes
The Effect of Improved Glycemic Control on the Composition and Function of High-Density Lipoproteins (HDL) in Patients With Type 1 Diabetes
The HAGI-T1D study aims to determine the effect of improved glycemic control on the composition and function of high-density lipoproteins (HDL) in patients with type 1 diabetes (T1D).
- Trial name
- HAGI-T1D (NCT07564752)
- Testing
- Blood test, Urine sample
- Where
- France
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Patients With Cardiovascular Disease, Healthy Participants
OCTA in Cardiovascular Disease and Healthy Controls
This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy…
- Trial name
- NCT07359664
- Testing
- Retinal vascular assessment using OCTA and SLDF
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
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