Clinical trials: Controlled Diabetes
Type 2 Diabetes Mellitus
Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus
Determine the safety and efficacy of MK-0431/ONO-5435 in patients with Type 2 diabetes mellitus who have inadequate glycemic control on diet/exercise therapy
- Trial name
- NCT00363844
- Testing
- Sitagliptin phosphate
- Where
- 8 sites in Japan
- Volunteers
- 209 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Diabetes, Diabetes Mellitus, Type 2
Comparison of NN1250 Versus Insulin Glargine in Subjects With Type 2 Diabetes
This trial is conducted in Europe and the United States of America (USA). The aim of this trial is to compare NN1250 (insulin degludec (IDeg)) with insulin glargine (IGlar) in subjects with type 2 diabetes never treated with…
- Trial name
- BEGIN™ (NCT00982644)
- Testing
- insulin degludec, insulin glargine
- Where
- 187 sites in United States, Austria and 13 more
- Volunteers
- 1,030 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus
Using Digital Health, Financial Incentives, and Community Health Worker Support to Change Health Behavior
This randomized controlled trial tests how digital health monitoring with financial incentives (DFI) and community health worker (CHW) support may affect how a person manages their diabetes.
- Trial name
- NCT03939793
- Testing
- IMPaCT Community Health Worker, Digital health monitoring with financial incentives, Usual Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pennsylvania
Type 2 Diabetes Mellitus
Effect of Dihydromirycetin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes Mellitus
Dihydromyricetin has demonstrated promising effects in glycemic control, insulin sensitivity and insulin secretion, that above mentioned findings show that dihydromyricetin has an excellent potential effect in the treatment of…
- Trial name
- NCT03606694
- Testing
- Dihydromyricetin, Metformin
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- University of Guadalajara
Diabetes, Diabete Mellitus
Empowerment-Based Health Education and Type 2 Diabetes Mellitus
Empowerment-based education may offer a sustainable approach to type 2 diabetes management, yet rigorous evidence within the Chinese healthcare context was lacking.
- Conditions
- Diabetes, Diabete Mellitus, Diabetes Mellitus, Type 2
- Trial name
- NCT07524166
- Testing
- Empowerment-Based Health Education
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eotvos Lorand University
Diabetes Mellitus
Turkish Nationwide SurvEy of Glycemic and Other Metabolic Parameters of Patients With Diabetes Mellitus-2 (TEMD-2 Study)
This study evaluates the metabolic control status, cardiovascular risk and frequency of comorbidities in diabetic patients followed in tertiary treatment centers in Turkey.
- Trial name
- TEMD-2 (NCT06347445)
- Testing
- There is no intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 5,707 people
- Sponsor
- Gulhane School of Medicine
Diabetes Mellitus, Type 1
Psychosocial Factors Affecting Glycemic Control in Children and Adolescents With Type 1 Diabetes Mellitus
The aim of the study is to research psychosocial and socioeconomic factors among families that might affect glycemic control in children and adolescent with type 1 diabetes mellitus.
- Trial name
- NCT04186195
- Where
- Finland
- Volunteers
- 191 people
- Sponsor
- Tampere University Hospital
Diabetes, Diabetes Mellitus, Type 1
Observational Study to Evaluate the Safety of Levemir® in Diabetes
This study is conducted in Africa, Asia, Europe, Japan and South America. The aim of this observational study is to evaluate the incidence of serious adverse reactions (SARs) while using Levemir® (insulin detemir) under normal…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- PREDICTIVE™ (NCT00659295)
- Testing
- insulin detemir
- Where
- 13 sites in Belgium, Czechia and 11 more
- Volunteers
- 51,170 people
- Sponsor
- Novo Nordisk A/S
Type II Diabetes Mellitus, Mixed Dyslipidemia
Diabetes and Combined Lipid Therapy Regimen (DIACOR) Study
The primary study hypothesis of this study is to determine whether there is a greater percentage of patients achieving a triglyceride level of <200 mg/dL with the combination of simvastatin 20 mg and fenofibrate 160mg than with…
- Trial name
- NCT00309712
- Testing
- fenofibrate 160 mg and simvastatin 20 mg
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Intermountain Health Care, Inc.
Diabetes, Diabetes Mellitus, Type 2
Observational Study in Type 2 Diabetes Treated by an Intensive Insulin Treatment (ICT) Containing Once Daily Levemir® (Insulin Detemir)
This study is conducted in Europe. The aim of this observational study is to gain practical experience with once-daily Levemir administration in type 2 diabetes patients who were previously treated with Insulatard®, Humulin® N…
- Trial name
- LEONCET2 (NCT00657930)
- Testing
- insulin detemir
- Where
- Hungary
- Volunteers
- 2,289 people
- Sponsor
- Novo Nordisk A/S
Diabetic Foot Ulcer
Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.
The goal of this clinical trial is to learn if using perinatal tissue allografts improves healing of chronic, non-healing foot ulcers in diabetic patients.
- Trial name
- NCT06437028
- Testing
- Dual-layer perinatal tissue allograft, Three-layer fenestrated perinatal tissue allograft, Standard of care
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Samaritan Biologics
Prediabetes, Obesity & Overweight
Human Pilot Study for the Investigation of the Role of Bilberry and Olive Bioactives on Oxidative Stress Parameters and Inflammatory Markers.
Numerous plant-based foods contain bioactive compounds, in particular polyphenols, which have antioxidant, anti-inflammatory, and metabolic regulatory effects.
- Conditions
- Prediabetes, Obesity & Overweight, Inflamation, Oxidative Stress
- Trial name
- BIOTRANSFORM (NCT07659028)
- Testing
- supplementation, food
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Diabetes Mellitus, Type 1, Child
Comparison Between Insulin Pump Treatment and Multiple Daily Insulin Injections in Diabetic Type 1 Children
Comparison between insulin pump treatment and multiple daily insulin injections in 38 children with type 1 diabetes4-16 years old. Outcome metabolic control, quality of life, impact of disease and cost effectiveness.
- Trial name
- NCT00462371
- Testing
- Insulin pump (CSII)
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Erasmus Medical Center
Type 2 Diabetes Mellitus
A Study of DBPR108 and Metformin Hydrochloride Combination Therapy in Patients With T2DM
This study aims to evaluate the efficacy and safety of DBPR108 tablets in combination with metformin hydrochloride in the treatment of type 2 diabetes mellitus.
- Trial name
- NCT04218734
- Testing
- DBPR108, metformin hydrochloride, placepo
- Where
- China
- Volunteers
- 214 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Type 2 Diabetes Mellitus
Effect of Conjugated Linoleic Acid Alone and in Conjunction With Vitamin E in Patients With Type 2 Diabetes Mellitus
Conjugated linoleic acids (CLAs) comprise a family of linoleic acid (18:2n-6; LA) isomers that are formed by biohydrogenation and oxidation processes in nature.
- Trial name
- NCT01099163
- Testing
- Tonalin SG1000T FFA
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Diabetic Polyneuropathy
Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Diabetic Polyneuropathy (Stage 1 or 2)
To assess clinical efficacy and safety of long-term orally administered thioctic acid in the treatment of diabetic polyneuropathy.
- Trial name
- NATHAN1 (NCT00977483)
- Testing
- Thioctic Acid
- Where
- 38 sites in United States, Croatia and 7 more
- Volunteers
- 460 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Colon Cancer Liver Metastasis, Inflammatory Response
Argipressin's Influence on Blood Loss During Hepatic Resection
Infusion of Argipressin during hepatic resection surgery may reduce blood loss. It may also reduce transfusion requirements, and mitigate the perioperative inflammatory response compared to placebo.
- Conditions
- Colon Cancer Liver Metastasis, Inflammatory Response, Vasopressin Causing Adverse Effects in Therapeutic Use
- Trial name
- ARG-01 (NCT05293041)
- Testing
- Argipressin
- Where
- Sweden
- Volunteers
- 248 people
- Sponsor
- Kristina Svennerholm
Pain, Neuropathic, Epilepsy
Cancer in Patients With Gabapentin (GPRD)
High doses of gabapentin are associated with pancreatic acinar cell tumors in rats, but there has been no post marketing pancreatic carcinogenicity signal with gabapentin as reported by spontaneous reports in AERS or in the…
- Conditions
- Pain, Neuropathic, Epilepsy, Renal Pelvis Cancer, Pancreatic Cancer
- Trial name
- NCT01236053
- Testing
- Gabapentin prescriptions
- Volunteers
- 2,323,608 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 2
PF-06291874 Multiple Ascending Dose Study In Type 2 Diabetes Mellitus Patients
The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending doses of PF-06291874 in Type 2 Diabetes patients.
- Trial name
- NCT01856595
- Testing
- PF-06291874
- Where
- 3 sites in United States
- Volunteers
- 117 people
- Sponsor
- Pfizer
Diabetes Mellitus Type 2
Multiple Dose Safety Tolerability, Pharmacokinetics And Midazolam Interaction In Healthy Overweight And Obese Subjects
This study is designed to assess the safety, tolerability and pharmacokinetics of multiple oral 200-mg doses of PF-05175157 administered twice daily for 14 days in healthy overweight and obese subjects.
- Trial name
- NCT01807377
- Testing
- PF-05175157, Midazolam
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Pfizer
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