Clinical trials: Controlled Diabetes
Diabete Mellitus, Foot Ulcer
Efficacy and Safety of Stimulan® for the Treatment of Diabetic Foot Osteomyelitis. The BIG D-FOOT Study
This study is designed as a double-blind, placebo-controlled, parallel series randomized trial aimed at verifying the effiicacy and safety of a local calcium-sulphate bio-absorbable antibiotic delivery (tobramicina+vancomicina)…
- Conditions
- Diabete Mellitus, Foot Ulcer, Osteomyelitis - Foot, Surgical Procedure, Unspecified
- Trial name
- BIG D-FOOT (NCT06262854)
- Testing
- Calcium-sulphate granules with tobramicina+vancomicina
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Heart Diseases, Stroke
The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women
This study will test whether a culturally-tailored nutrition and exercise intervention designed for African-American women will lead to sustained improvements in exercise and healthy eating through improvements in self-management…
- Conditions
- Heart Diseases, Stroke, Pre-diabetes, Hypertension
- Trial name
- NCT04705779
- Testing
- HARMONY, Nutrition and Exercise Education (NEEW)
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of North Carolina, Chapel Hill
Dental Implant, Diabetes Mellitus, Type 2
Bioactive Microstructured Anti Microbial Precoated Surface Implant Versus Non-coated Surface Implant in Type 2 Diabetic Patients in the Mandible
Dental implant's surface properties significantly influence both biological and mechanical integration. Surface bio-treatment could accelerate and enhance bone regeneration, ensuring successful implantation.
- Trial name
- NCT06528327
- Testing
- Pre coated impants, Non coated implant surface
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Hams Hamed Abdelrahman
PreDiabetes, Overweight and Obesity
Effect of a Probiotic on the Glycemic Profile and the Fecal Microbiota of Prediabetic Subjects (PREDIABETCARE)
According to the data from the Di@bet.es study, which is part of the National Diabetes Strategy, the prevalence of type 2 diabetes among Spanish population is 13.8%.
- Trial name
- PREDIABETCAR (NCT04863313)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Type 1 Diabetes Mellitus
Study of IMCY-0098 in Patients With Recent Onset Type 1 Diabetes
This clinical study will evaluate the safety of an innovative approach expected to be disease-modifying by stopping the auto-immune-mediated destruction of islet β-cells in the pancreas.
- Trial name
- NCT03272269
- Testing
- IMCY-0098
- Where
- 17 sites in Belgium, Denmark and 5 more
- Volunteers
- 41 people
- Sponsor
- Imcyse SA
Type 2 Diabetes Mellitus
Multiple Ascending Dose Trial of BYK324677 in Healthy Volunteers
This monocenter trial is conducted to obtain first data on safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) after multiple ascending doses of BYK324677 in humans.
- Trial name
- NCT01386541
- Testing
- BYK324677
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Nycomed
Gingival Scaling, Metabolic Control
The Effect of Oral Hygiene and Full Mouth Scaling on Metabolic Control in Patients With Type II Diabetes
The aim of the study is to evaluate the effect of non-surgical periodontal therapy, consisting of oral hygiene instruction, full mouth scaling and an antimicrobial rinse on the metabolic control of chronic periodontitis patients…
- Trial name
- NCT01255254
- Testing
- Gingival scaling
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rambam Health Care Campus
Diabetes Mellitus, Type 2
The Effect of Diabetes Coaching on Distress and Diabetes Self-Management
This research is a randomized controlled, experimental study planned to evaluate the effect of diabetes coaching on diabetes self-management, glycosylated hemoglobin and diabetes distress levels in individuals with type 2…
- Trial name
- NCT06265181
- Testing
- Diabetes coaching
- Volunteers
- 64 people
- Sponsor
- Abant Izzet Baysal University
Type 2 Diabetes Mellitus (T2DM)
Interventional Study of Active Weight Management in Patients With Type 2 Diabetes and Obesity in Routine Clinical Practice During 12 Months.
This study was aimed to achieve of long-term weight loss in T2DM patients by use of comprehensive lifestyle changes program, providing patients with structured diet, exercise plan, group behavioral support and group education.
- Trial name
- NCT02670928
- Testing
- Lifestyle intervention
- Where
- 2 sites in Russia
- Volunteers
- 130 people
- Sponsor
- Novartis Pharmaceuticals
Hypertriglyceridemia, Type 2 Diabetes
Assess Efficacy and Safety of Epeleuton in Patients With Hypertriglyceridemia and Type 2 Diabetes
To assess the efficacy and safety of orally administered Epeleuton capsules versus placebo, in the treatment of adult patients with hypertriglyceridemia and type 2 diabetes
- Trial name
- TRIAGE (NCT04365400)
- Testing
- DS102
- Where
- 56 sites in United States, Georgia and 4 more
- Volunteers
- 233 people
- Sponsor
- Afimmune
Type 2 Diabetes
Digital Health Navigation for Latino Patients With Type II Diabetes
The goal of this clinical trial is to learn about digital literacy training in adult, Latino patient with type II diabetes. The main question it aims to answer is: Can providing digital literacy training during a hospital…
- Trial name
- NCT06283992
- Testing
- Digital Navigation
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Brigham and Women's Hospital
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Diabetes
A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of Oral ZYGK1 in Healthy Volunteers
The purpose of this study is to determine (1) whether ZYGK1 is safe and well tolerated, (2) the pharmacokinetics (what body does to ZYGK1) and (3) pharmacodynamics (what drugs does to the body) in the healthy and diabetic subject.
- Trial name
- NCT01472809
- Testing
- ZYGK1
- Where
- India
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Zydus Lifesciences Limited
Diabetes Mellitus, Diabetic Foot Ulcer
Relaxation Intervention in Patients With Diabetic Foot Ulcer
Diabetic foot ulcers (DFU) are one of the most serious complications of diabetes and can lead to amputations in 85% of cases, resulting in physical, psychological, family, social and economic consequences.
- Trial name
- NCT04652999
- Testing
- Muscle Relaxation with Guided Imagery, Neutral Guided Imagery
- Where
- 2 sites in Portugal
- Volunteers
- 54 people
- Sponsor
- University of Minho
Type 1 Diabetes Mellitus
Study Assessing an Insulin Pump-controlling Algorithm to Minimize Hypo and Hyper in Type 1 During CRC Setting
Feasibility study assessing the ability of an insulin pump-controlling algorithm to minimize hypoglycemia and hyperglycemia in patients with type 1 diabetes in a clinical research setting.
- Trial name
- NCT01638299
- Testing
- Hypo-Hyper Minimizer (HHM) System
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Animas Corporation
Type 2 Diabetes Mellitus
Study of Rivoglitazone in Type 2 Diabetes Mellitus
This is a 26-week study in subjects with type 2 diabetes currently sub-optimally controlled by diet and exercise or with non-thiazolidinedione antihyperglycemic monotherapy.
- Trial name
- NCT00484198
- Testing
- Pioglitazone, Rivoglitazone
- Where
- 183 sites in United States, Argentina and 16 more
- Volunteers
- 1,912 people
- Sponsor
- Daiichi Sankyo
Type 2 Diabetes Mellitus
Omarigliptin (MK-3102) Clinical Trial - Placebo- and Sitagliptin-Controlled Monotherapy Study in Japanese Patients With Type 2 Diabetes Mellitus (MK-3102-020)
The purpose of this study is to assess the efficacy of omarigliptin 25 mg weekly (as monotherapy) compared with sitagliptin 50 mg daily and placebo, and the long term safety (up to 52 weeks) of omarigliptin 25 mg weekly.
- Trial name
- NCT01703221
- Testing
- Omarigliptin, Sitagliptin
- Volunteers
- 414 people
- Sponsor
- Merck Sharp & Dohme LLC
Gestational Diabetes Mellitus
The Impact of Vitamin D Supplementation on Glucose Metabolism in Chinese Women With Former Gestational Diabetes Mellitus
Vitamin D deficiency are related to insulin resistance and impaired beta-cell function.It is reported that the level of vitamin D is lower during pregnancy and postpartum in the women with Gestational Diabetes Mellitus.
- Trial name
- NCT03138616
- Testing
- vitamin D
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Diabetes
Evaluation of Glucose Monitoring Methods: Characterizing Glycemic Control in Subjects With Diabetes
Evaluate the usefulness of continuous glucose monitoring devices in terms of their ability to identify periods throughout the day when glucose varies significantly.
- Trial name
- NCT00805506
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- HealthPartners Institute
Diabetic Polyneuropathy
A Double-Blind, Placebo-Controlled Study of Fermented Deglycyrrhizinated Licorice Extract
This double-blind, placebo-controlled study evaluated the efficacy of oral α-amylase enzyme replacement therapy in treating early-stage diabetic polyneuropathy (DPN).
- Trial name
- NCT07148804
- Testing
- Fermented Deglycyrrhizinated Licorice, Non-fermented Deglycyrrhizinated Licorice
- Where
- Egypt
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Helwan University
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